每日简报

PanelMatch：时间序列截面数据因果推断的匹配方法AI 解读

Analyzing time-series cross-sectional (also known as longitudinal or panel) data is an important process across a number of fields, including the social sciences, economics, finance, and medicine. PanelMatch is an R package that implements a set of tools enabling researchers to apply matching methods for causal inference with time-series cross-sectional data. Relative to other commonly used methods for longitudinal analyses, like regression with fixed effects, the…

大语言模型能否辅助因果发现的实验设计？AI 解读

Designing proper experiments and selecting optimal intervention targets is a longstanding problem in scientific or causal discovery. Identifying the underlying causal structure from observational data alone is inherently difficult. Obtaining interventional data, on the other hand, is crucial to causal discovery, yet it is usually expensive and time-consuming to gather sufficient interventional data to facilitate causal discovery. Previous approaches commonly utilize…

因果协变量应当平衡到什么程度？AI 解读

Covariate balancing is a popular technique for controlling confounding in observational studies. It finds weights for the treatment group which are close to uniform, but make the group's covariate means (approximately) equal to those of the entire sample. A crucial question is: how approximate should the balancing be, in order to minimize the error of the final estimate? Current guidance is derived from heuristic or asymptotic analyses, which are uninformative when the size…

层级纵向研究中的半参数生长曲线建模AI 解读

Modeling of growth (or decay) curves arises in many fields such as microbiology, epidemiology, marketing, and econometrics. Parametric forms like Logistic and Gompertz are often used for modeling such monotonic patterns. While useful for compact description, the real-life growth curves rarely follow these parametric forms perfectly. Therefore, the curve estimation methods that strike a balance between prior information in the parametric form and fidelity with the observed…

利用有效工具变量与机器学习推断异质处理效应AI 解读

We introduce a new instrumental variable (IV) estimator for heterogeneous treatment effects in the presence of endogeneity. Our estimator is based on double/debiased machine learning (DML) and uses efficient machine learning instruments (MLIV) and kernel smoothing. We prove consistency and asymptotic normality of our estimator and also construct confidence sets that are more robust towards weak IV. Along the way, we also provide an accessible discussion of the corresponding…

随机对照试验中存在竞争性伴发事件的处理效应估计AI 解读

The analysis of randomized controlled trials is often complicated by intercurrent events (IEs) -- events that occur after treatment initiation and affect either the interpretation or existence of outcome measurements. Examples include treatment discontinuation or the use of additional medications. In two recent clinical trials for systemic lupus erythematosus with complications of IEs, we classify the IEs into two broad categories: effect-informative (e.g., treatment…

消费者如何选择：用混合专家模型揭示潜在偏好AI 解读

Understanding consumer choice is fundamental to marketing and management research, as firms increasingly seek to personalize offerings and optimize customer engagement. Traditional choice modeling frameworks, such as multinomial logit (MNL) and mixed logit models, impose rigid parametric assumptions that limit their ability to capture the complexity of consumer decision-making. This study introduces the Mixture of Experts (MoE) framework as a machine learning-driven…

整合误分类电子病历结局与非概率样本中的验证结局AI 解读

Although increasingly used for research, electronic health records (EHR) often lack gold-standard assessment of key data elements. Linking EHRs to other data sources with higher-quality measurements can improve statistical inference, but such analyses must account for selection bias if the linked data source arises from a non-probability sample. We propose a set of novel estimators targeting the average treatment effect (ATE) that combine information from binary outcomes…

可用于决策的治疗效应异质性：评估与检验AI 解读

Developing tools for estimating heterogeneous treatment effects (HTE) and individualized treatment effects has been an area of active research in recent years. While these tools have proven to be useful in many contexts, a concern when deploying such methods is the degree to which incorporating HTE into a prediction model provides an advantage over predictive methods which do not allow for variation in treatment effect across individuals. To address this concern, we propose…

小样本断点回归设计的部分线性估计量AI 解读

Regression discontinuity (RD) designs are a popular approach to estimating a treatment effect of cutoff-based interventions. Two current estimation approaches dominate the literature. One fits separate regressions on either side of the cutoff, and the other performs finite sample inference based on a local randomization assumption. Recent developments of these approaches have often focused on asymptotic properties and large sample sizes. Educational applications often…

何时可以使用双向固定效应回归？AI 解读

The use of the two-way fixed effects regression in empirical social science was historically motivated by folk wisdom that it uncovers the Average Treatment effect on the Treated (ATT) as in the canonical two-period two-group case. This belief has come under scrutiny recently due to recent results in applied econometrics showing that it fails to uncover meaningful averages of heterogeneous treatment effects in the presence of effect heterogeneity over time and across…

通过逆向加权将汇总数据纳入可作因果解释的元分析AI 解读

Obtaining causally interpretable meta-analysis results is challenging when there are differences in the distribution of effect modifiers between eligible trials. To overcome this, recent work on transportability methods has considered standardizing results of individual studies over the case-mix of a target population, prior to pooling them as in a classical random-effect meta-analysis. One practical challenge, however, is that case-mix standardization often requires…

黑箱因果推断：通过元预测估计效应AI 解读

Causal inference and the estimation of causal effects plays a central role in decision-making across many areas, including healthcare and economics. Estimating causal effects typically requires an estimator that is tailored to each problem of interest. But developing estimators can take significant effort for even a single causal inference setting. For example, algorithms for regression-based estimators, propensity score methods, and doubly robust methods were designed…

结构因果模型的极端行为AI 解读

The behavior of extreme observations is well-understood for time series or spatial data, but little is known if the data generating process is a structural causal model (SCM). We study the behavior of extremes in this model class, both for the observational distribution and under extremal interventions. We show that under suitable regularity conditions on the structure functions, the extremal behavior is described by a multivariate Pareto distribution, which can be…

利用伪观测进行协变量调整的限制平均生存时间贝叶斯分析AI 解读

The difference in restricted mean survival time (RMST) is a clinically meaningful measure to quantify treatment effect in randomized controlled trials, especially when the proportional hazards assumption does not hold. Several frequentist methods exist to estimate RMST adjusted for covariates based on modeling and integrating the survival function. A more natural approach may be a regression model on RMST using pseudo-observations, which allows for a direct estimation…

函数型因果效应的核估计方法AI 解读

We propose causal effect estimators based on empirical Fréchet means and operator-valued kernels, tailored to functional data spaces. These methods address the challenges of high-dimensionality, sequential ordering, and model complexity while preserving robustness to treatment misspecification. Using structural assumptions, we obtain compact representations of potential outcomes, enabling scalable estimation of causal effects over time and across covariates. We provide both…

非正态变换模型下的协变量调整边际推断AI 解读

Although treatment effects can be estimated from observed outcome distributions obtained from proper randomization in clinical trials, covariate adjustment is recommended to increase precision. For important treatment effects, such as odds or hazard ratios, conditioning on covariates in binary logistic or proportional hazards models changes the interpretation of the treatment effect and conditioning on different sets of covariates renders the resulting effect estimates…

带软单纯形约束的贝叶斯合成控制AI 解读

The challenges posed by high-dimensional data and use of the simplex constraint are two major concerns in the empirical application of the synthetic control method (SCM) in econometric studies. To address both issues simultaneously, we propose a Bayesian SCM that integrates a soft simplex constraint within spike-and-slab variable selection. The hierarchical prior structure captures the extent to which the data supports the simplex constraint, allowing for more efficient and…

数百种机器学习分类器与离散选择模型的出行预测比较：实证基准AI 解读

Numerous studies have compared machine learning (ML) and discrete choice models (DCMs) in predicting travel demand. However, these studies often lack generalizability as they compare models deterministically without considering contextual variations. To address this limitation, our study develops an empirical benchmark by designing a tournament model, thus efficiently summarizing a large number of experiments, quantifying the randomness in model comparisons, and using formal…

网络干扰下的邻域自适应因果效应估计AI 解读

Estimating causal effects has become an integral part of most applied fields. In this work we consider the violation of the classical no-interference assumption with units connected by a network. For tractability, we consider a known network that describes how interference may spread. Unlike previous work the radius (and intensity) of the interference experienced by a unit is unknown and can depend on different (local) sub-networks and the assigned treatments. We study…

估计平均处理效应的双重机器学习方法：比较研究AI 解读

Observational cohort studies are increasingly being used for comparative effectiveness research to assess the safety of therapeutics. Recently, various doubly robust methods have been proposed for average treatment effect estimation by combining the treatment model and the outcome model via different vehicles, such as matching, weighting, and regression. The key advantage of doubly robust estimators is that they require either the treatment model or the outcome model to be…

lpcde：局部多项式条件密度估计与推断AI 解读

This paper discusses the R package lpcde, which stands for local polynomial conditional density estimation. It implements the kernel-based local polynomial smoothing methods introduced in Cattaneo, Chandak, Jansson, Ma (2024) for statistical estimation and inference of conditional distributions, densities, and derivatives thereof. The package offers mean square error optimal bandwidth selection and associated point estimators, as well as uncertainty quantification based on…

通过主成分网络回归估计网络中介因果效应AI 解读

We develop a method to decompose causal effects on a social network into an indirect effect mediated by the network, and a direct effect independent of the social network. To handle the complexity of network structures, we assume that latent social groups act as causal mediators. We develop principal components network regression models to differentiate the social effect from the non-social effect. Fitting the regression models is as simple as principal components analysis…

分位数积分的非参数统计推断基础AI 解读

We present a general non-parametric statistical inference theory for integrals of quantiles without assuming any specific sampling design or dependence structure. Technical considerations are accompanied by examples and discussions, including those pertaining to the bias of empirical estimators. To illustrate how the general results can be adapted to specific situations, we derive - at a stroke and under minimal conditions - consistency and asymptotic normality of the…