每日简报

含协变量的高斯图回归模型的凸估计AI 解读

Gaussian graphical models (GGMs) are widely used to recover the conditional independence structure among random variables. Recent work has sought to incorporate auxiliary covariates to improve estimation, particularly in applications such as co-expression quantitative trait locus (eQTL) studies, where both gene expression levels and their conditional dependence structure may be influenced by genetic variants. Existing approaches to covariate-adjusted GGMs either restrict…

panelPomp：在 R 中利用部分可观测马尔可夫过程分析面板数据AI 解读

Panel data arise when time series measurements are collected from multiple, dynamically independent but structurally related systems. Each system's time series can be modeled as a partially observed Markov process (POMP), and the ensemble of these models is called a PanelPOMP. If the time series are relatively short, statistical inference for each time series must draw information from across the entire panel. The component systems in the panel are called units; model…

利用替代控制结果进行弱假设数据整合后推断AI 解读

Data integration methods aim to extract low-dimensional embeddings from high-dimensional outcomes to remove unwanted variations, such as batch effects and unmeasured covariates, across heterogeneous datasets. However, multiple hypothesis testing after integration can be biased due to data-dependent processes. We introduce a robust post-integrated inference method that accounts for latent heterogeneity by utilizing control outcomes. Leveraging causal interpretations, we…

交叉试验的统计方法：经典与近期进展综述AI 解读

A comprehensive review of the literature on crossover design is needed to highlight its evolution, applications, and methodological advancements across various fields. Given its widespread use in clinical trials and other research domains, understanding this design's challenges, assumptions, and innovations is essential for optimizing its implementation and ensuring accurate, unbiased results. This article extensively reviews the history and statistical inference methods for…

rdid 与 rdidstag：稳健双重差分的 Stata 命令AI 解读

This article provides a Stata package for the implementation of the robust difference-in-differences (RDID) method developed in Ban and Kédagni (2023). It contains three main commands: $\texttt{rdid}$, $\texttt{rdid_dy}$, $\texttt{rdidstag}$, which we describe in the introduction and the main text. We illustrate these commands through simulations and empirical examples.

解码神经网络：基于因果解释与推理的针对性稳健分析AI 解读

Despite their success and widespread adoption, the opaque nature of deep neural networks (DNNs) continues to hinder trust, especially in critical applications. Current interpretability solutions often yield inconsistent or oversimplified explanations, or require model changes that compromise performance. In this work, we introduce TRACER, a novel method grounded in causal inference theory designed to estimate the causal dynamics underpinning DNN decisions without altering…

跨人群与研究设计比较 HIV 疫苗免疫原性AI 解读

Safe and effective preventive vaccines have the potential to help stem the HIV epidemic. The efficacy of such vaccines is typically measured in randomized, double-blind phase IIb/III trials and described as a reduction in newly acquired HIV infections. However, such trials are often expensive, time-consuming, and/or logistically challenging. These challenges lead to a great interest in immune responses induced by vaccination, and in identifying which immune responses predict…

利用因果不变贝叶斯神经网络实现稳健域泛化AI 解读

Deep neural networks can obtain impressive performance on various tasks under the assumption that their training domain is identical to their target domain. Performance can drop dramatically when this assumption does not hold. One explanation for this discrepancy is the presence of spurious domain-specific correlations in the training data that the network exploits. Causal mechanisms, in the other hand, can be made invariant under distribution changes as they allow…

未测量混杂下异质性处理效应的非参数直接学习方法AI 解读

In many social, behavioral, and biomedical sciences, treatment effect estimation is a crucial step in understanding the impact of an intervention, policy, or treatment. In recent years, an increasing emphasis has been placed on heterogeneity in treatment effects, leading to the development of various methods for estimating Conditional Average Treatment Effects (CATE). These approaches hinge on a crucial identifying condition of no unmeasured confounding, an assumption that…

临床试验常用模式混合模型的直接估计AI 解读

Pattern-mixture models have received increasing attention as they are commonly used to assess treatment effects in primary or sensitivity analyses for clinical trials with nonignorable missing data. Pattern-mixture models have traditionally been implemented using multiple imputation, where the variance estimation may be a challenge because the Rubin's approach of combining between- and within-imputation variance may not provide consistent variance estimation while bootstrap…

利用多来源观察数据开展鲁棒离线策略学习AI 解读

We consider the problem of using observational bandit feedback data from multiple heterogeneous data sources to learn a personalized decision policy that robustly generalizes across diverse target settings. To achieve this, we propose a minimax regret optimization objective to ensure uniformly low regret under general mixtures of the source distributions. We develop a policy learning algorithm tailored to this objective, combining doubly robust offline policy evaluation…

度修正混合成员模型中参数的最优估计AI 解读

With the rise of big data, networks have pervaded many aspects of our daily lives, with applications ranging from the social to natural sciences. Understanding the latent structure of the network is thus an important question. In this paper, we model the network using a Degree-Corrected Mixed Membership (DCMM) model, in which every node $i$ has an affinity parameter $θ_i$, measuring the degree of connectivity, and an intrinsic membership probability vector $π_i = (π_1, \cdots π_K)$…

大规模纵向实验：估计与推断AI 解读

Large-scale randomized experiments are seldom analyzed using panel regression methods because of computational challenges arising from the presence of millions of nuisance parameters. We leverage Mundlak's insight that unit intercepts can be eliminated by using carefully chosen averages of the regressors to rewrite several common estimators in a form that is amenable to weighted-least squares estimation with frequency weights. This renders regressions involving arbitrary…

结局独立的非随机缺失混杂下：因果效应界限与敏感性分析AI 解读

We report assumption-free bounds for any contrast between the probabilities of the potential outcome under exposure and non-exposure when the confounders are missing not at random. We assume that the missingness mechanism is outcome-independent. We also report a sensitivity analysis method to complement our bounds.

利用偏度准则处理因果发现中的异方差噪声AI 解读

Real-world data often violates the equal-variance assumption (homoscedasticity), making it essential to account for heteroscedastic noise in causal discovery. In this work, we explore heteroscedastic symmetric noise models (HSNMs), where the effect $Y$ is modeled as $Y = f(X) + σ(X)N$, with $X$ as the cause and $N$ as independent noise following a symmetric distribution. We introduce a novel criterion for identifying HSNMs based on the skewness of the score (i.e., the…

纵向因果推断中治疗模型的自适应稀疏化与平滑AI 解读

Causal variable selection in time-varying treatment settings is challenging due to evolving confounding effects. Existing methods mainly focus on time-fixed exposures and are not directly applicable to time-varying scenarios. We propose a novel two-step procedure for variable selection when modeling the treatment probability at each time point. We first introduce a novel approach to longitudinal confounder selection using a Longitudinal Outcome Adaptive LASSO (LOAL) that…

多组临床试验中死亡截断结局的双重稳健估计与敏感性分析AI 解读

In clinical trials, the observation of participant outcomes may frequently be hindered by death, leading to ambiguity in defining a scientifically meaningful final outcome for those who die. Principal stratification methods are valuable tools for addressing the average causal effect among always-survivors, i.e., the average treatment effect among a subpopulation defined as those who would survive regardless of treatment assignment. Although robust methods for the…

政策学习中最优福利的置信下界AI 解读

We study inference on the optimal welfare in a policy learning problem and propose reporting a lower confidence band (LCB). A natural approach to constructing an LCB is to invert a one-sided t-test based on an efficient estimator for the optimal welfare. However, we show that for an empirically relevant class of DGPs, such an LCB can be first-order dominated by an LCB based on a welfare estimate for a suitable suboptimal treatment policy. We show that such first-order…

内生网络图上的实验设计与效应估计AI 解读

We study experimentation under endogenous network interference. Interference patterns are mediated by an endogenous graph, where edges can be formed or eliminated as a result of treatment. We show that conventional estimators are biased in these circumstances, and present a class of unbiased, consistent and asymptotically normal estimators of total treatment effects in the presence of such interference. We show via simulation that our estimator outperforms existing…

联立图式动态建模AI 解读

We review theory and methodology of the class of simultaneous graphical dynamic linear models (SGDLMs) that provide flexibility, parsimony and scalability of multivariate time series analysis. Discussion includes core theoretical aspects and summaries of existing Bayesian methodology for forward filtering and forecasting with SGDLMs. The review is complemented by new theory linking dynamic graphical and factor models, and extensions of the Bayesian methodology. This…

结合实验前与实验中数据降低处理效应估计方差AI 解读

Online controlled experiments (A/B testing) are fundamental to data-driven decision-making in many companies. Improving the sensitivity of these experiments under fixed sample size constraints requires reducing the variance of the average treatment effect (ATE) estimator. Existing variance reduction techniques such as CUPED and CUPAC use pre-experiment data, but their effectiveness depends on how predictive those data are for outcomes measured during the experiment.…

Nickell 遇上 Stambaugh：面板预测回归中的双重偏差AI 解读

In panel predictive regressions with persistent covariates, coexistence of the Nickell bias and the Stambaugh bias imposes challenges for estimation and hypothesis testing. This paper introduces an innovative estimator, the Double IVX (DIVX), inspired by the IVX technique in time series. DIVX effectively removes this composite Nickell-Stambaugh bias and reinstates standard inferential procedures based on the t-statistic. This new procedure achieves unified inference across a…

以集中指数为目标的健康不平等因果推断AI 解读

A concentration index, a standardized covariance between a health variable and relative income ranks, is often used to quantify income-related health inequalities. There is a lack of formal approach to study the effect of an exposure, e.g., education, on such measures of inequality. In this paper we contribute by filling this gap and developing the necessary theory and method. Thus, we define a counterfactual concentration index for different levels of an exposure. We give…

空间混杂的因果推断框架AI 解读

Over the past few decades, addressing "spatial confounding" has become a major topic in spatial statistics. However, the literature has provided conflicting definitions, and many proposed solutions are tied to specific analysis models and do not address the issue of confounding as it is understood in causal inference. We offer an analysis-model-agnostic definition of spatial confounding as the existence of an unmeasured causal confounder variable with a spatial structure. We…