How should parallel cluster randomized trials with a baseline period be analyzed? A survey of estimands and common estimators
带基线期的平行整群随机试验:估计目标与常用估计量
The parallel cluster randomized trial with baseline (PB-CRT) is a common variant of the standard parallel cluster randomized trial (P-CRT). We define two natural estimands in the context of PB-CRTs with informative cluster sizes, the participant-average treatment effect (pATE) and cluster-average treatment effect (cATE), to address participant and cluster-level hypotheses. In this work, we theoretically derive the convergence of the unweighted and inverse cluster-period size…