每日简报

误差可预测时的反事实结果插补AI 解读

A crucial input into causal inference is the imputed counterfactual outcome. Imputation error can arise because of sampling uncertainty from estimating the prediction model using the untreated observations, or from out-of-sample information not captured by the model. While the literature has focused on sampling uncertainty, it vanishes with the sample size. Often overlooked is the possibility that the out-of-sample error can be informative about the missing counterfactual…

极端处理效应：向极端处理范围外推剂量反应函数AI 解读

The potential outcomes framework serves as a fundamental tool for quantifying causal effects. The average dose-response function (also called the effect curve), denoted as (μ(t)), is typically of interest when dealing with a continuous treatment variable (exposure). The focus of this work is to determine the impact of an extreme level of treatment, potentially beyond the range of observed values--that is, estimating (μ(t)) for very large (t). Our approach is grounded in the…

双重高维线性混合模型下异质图模型的推断AI 解读

Inferring the structure of population-level functional connectivity networks from multi-subject functional magnetic resonance imaging data is essential for understanding the connectivity patterns underlying cognitive and behavioral functions. Graphical models provide a formal statistical framework for inferring the graph structure. However, the multi-level nature of functional magnetic resonance imaging data---where each level corresponds, for instance, to a…

观察研究因果推断中 Mann–Whitney–Wilcoxon 秩和统计量的双重稳健估计AI 解读

The Mann-Whitney-Wilcoxon rank sum test (MWWRST) is a widely used method for comparing two treatment groups in randomized control trials, particularly when dealing with highly skewed data. However, when applied to observational study data, the MWWRST often yields invalid results for causal inference. To address this limitation, Wu et al. (2014) introduced an approach that incorporates inverse probability weighting (IPW) into this rank-based statistics to mitigate confounding…

中位数处理效应的近似极限AI 解读

Average Treatment Effect (ATE) estimation is a well-studied problem in causal inference. However, it does not necessarily capture the heterogeneity in the data, and several approaches have been proposed to tackle the issue, including estimating the Quantile Treatment Effects. In the finite population setting containing $n$ individuals, with treatment and control values denoted by the potential outcome vectors $\mathbf{a}, \mathbf{b}$, much of the prior work focused on…

用长期平均风险评估免疫治疗的延迟获益AI 解读

Delayed treatment effects on time-to-event outcomes have often been observed in randomized controlled studies of cancer immunotherapies. In the case of delayed onset of treatment effect, the conventional test/estimation approach using the log-rank test for between-group comparison and Cox's hazard ratio to estimate the magnitude of treatment effect is not optimal, because the log-rank test is not the most powerful option, and the interpretation of the resulting hazard ratio…

用于纵向异质性处理效应推断的常微分方程发现AI 解读

Inferring unbiased treatment effects has received widespread attention in the machine learning community. In recent years, our community has proposed numerous solutions in standard settings, high-dimensional treatment settings, and even longitudinal settings. While very diverse, the solution has mostly relied on neural networks for inference and simultaneous correction of assignment bias. New approaches typically build on top of previous approaches by proposing new (or…

重复测量中介与结局的连续时间中介分析AI 解读

Mediation analysis aims to decipher the underlying causal mechanisms between an exposure, an outcome, and intermediate variables called mediators. Initially developed for fixed-time mediator and outcome, it has been extended to the framework of longitudinal data by discretizing the assessment times of mediator and outcome. Yet, processes in play in longitudinal studies are usually defined in continuous time and measured at irregular and subject-specific visits. This is the…

算法化的句法因果识别AI 解读

Causal identification in causal Bayes nets (CBNs) is an important tool in causal inference allowing the derivation of interventional distributions from observational distributions where this is possible in principle. However, most existing formulations of causal identification using techniques such as d-separation and do-calculus are expressed within the mathematical language of classical probability theory on CBNs. However, there are many causal settings where probability…

纵向修正处理政策的中介效应识别与估计AI 解读

We demonstrate a comprehensive semiparametric approach to causal mediation analysis, addressing the complexities inherent in settings with longitudinal and continuous treatments, confounders, and mediators. Our methodology utilizes a nonparametric structural equation model and a cross-fitted sequential regression technique based on doubly robust pseudo-outcomes, yielding an efficient, asymptotically normal estimator without relying on restrictive parametric modeling…

主分层可忽略性下基于 U 统计量的主分层推断AI 解读

Principal stratification is a popular framework for causal inference in the presence of an intermediate outcome. While the principal average treatment effects are the standard target of inference, they may be insufficient when interest lies in the relative ordering of potential outcomes within a principal stratum. We introduce the principal generalized causal effect estimands to accommodate nonlinear contrast functions, providing robust, probability-scale summaries suitable…

基于图机器学习的网络因果效应双重稳健估计AI 解读

We address the challenge of inferring causal effects in social network data. This results in challenges due to interference -- where a unit's outcome is affected by neighbors' treatments -- and network-induced confounding factors. While there is extensive literature focusing on estimating causal effects in social network setups, a majority of them make prior assumptions about the form of network-induced confounding mechanisms. Such strong assumptions are rarely likely to…

贝叶斯博弈中信息结构的识别AI 解读

To what extent can an external observer infer the underlying information structure from an equilibrium action distribution in an incomplete-information game? We investigate this question in a general linear-quadratic-Gaussian framework. A simple class of canonical information structures is offered and proves rich enough to rationalize any equilibrium action distribution that can arise under an arbitrary information structure. Moreover, this class is parsimonious in the sense…

通过 Riesz 回归实现自动去偏机器学习AI 解读

A variety of interesting parameters may depend on high dimensional regressions. Machine learning can be used to estimate such parameters. However estimators based on machine learners can be severely biased by regularization and/or model selection. Debiased machine learning uses Neyman orthogonal estimating equations to reduce such biases. Debiased machine learning generally requires estimation of unknown Riesz representers. A primary innovation of this paper is to provide…

移动健康零膨胀计数结果的因果偏离效应：非参数估计方法AI 解读

In mobile health, tailoring interventions for real-time delivery is of paramount importance. Micro-randomized trials have emerged as the "gold-standard" methodology for developing such interventions. Analyzing data from these trials provides insights into the efficacy of interventions and the potential moderation by specific covariates. The "causal excursion effect", a novel class of causal estimand, addresses these inquiries. Yet, existing research mainly focuses on…

可能相依观测下近乎最优的非参数序贯检验与置信序列AI 解读

Sequential tests and their implied confidence sequences, which are valid at arbitrary stopping times, promise flexible statistical inference and on-the-fly decision making. However, strong guarantees are limited to parametric sequential tests that under-cover in practice or concentration-bound-based sequences that over-cover and have suboptimal rejection times. In this work, we consider classic delayed-start normal-mixture sequential probability ratio tests, and we provide…

时间一致的中心极限定理与渐近置信序列AI 解读

Confidence intervals based on the central limit theorem (CLT) are a cornerstone of classical statistics. Despite being only asymptotically valid, they are ubiquitous because they permit statistical inference under weak assumptions and can often be applied to problems even when nonasymptotic inference is impossible. This paper introduces time-uniform analogues of such asymptotic confidence intervals, adding to the literature on confidence sequences (CS) -- sequences of…

随机试验重加权推广：有限样本误差与变量选择AI 解读

Randomized Controlled Trials (RCTs) may suffer from limited scope. In particular, samples may be unrepresentative: some RCTs over- or under- sample individuals with certain characteristics compared to the target population, for which one wants conclusions on treatment effectiveness. Re-weighting trial individuals to match the target population can improve the treatment effect estimation. In this work, we establish the exact expressions of the bias and variance of such…

自兼容性：在没有真实因果结构时评估因果发现AI 解读

As causal ground truth is incredibly rare, causal discovery algorithms are commonly only evaluated on simulated data. This is concerning, given that simulations reflect preconceptions about generating processes regarding noise distributions, model classes, and more. In this work, we propose a novel method for falsifying the output of a causal discovery algorithm in the absence of ground truth. Our key insight is that while statistical learning seeks stability across subsets…

连续处理下的双重稳健近端因果学习AI 解读

Proximal causal learning is a promising framework for identifying the causal effect under the existence of unmeasured confounders. Within this framework, the doubly robust (DR) estimator was derived and has shown its effectiveness in estimation, especially when the model assumption is violated. However, the current form of the DR estimator is restricted to binary treatments, while the treatment can be continuous in many real-world applications. The primary obstacle to…

马尔可夫等价类中的条件协变量调整AI 解读

We consider the problem of identifying a conditional causal effect through covariate adjustment. We focus on the setting where the causal graph is known up to one of two types of graphs: a maximally oriented partially directed acyclic graph (MPDAG) or a partial ancestral graph (PAG). Both MPDAGs and PAGs represent equivalence classes of possible underlying causal models. After defining adjustment sets in this setting, we provide a necessary and sufficient graphical criterion…

高维观察数据中稳健处理效应评估的两阶段特征选择AI 解读

A Randomized Control Trial (RCT) is considered as the gold standard for evaluating the effect of any intervention or treatment. However, its feasibility is often hindered by ethical, economical, and legal considerations, making observational data a valuable alternative for drawing causal conclusions. Nevertheless, healthcare observational data presents a difficult challenge due to its high dimensionality, requiring careful consideration to ensure unbiased, reliable, and…

用于因果推断的调查校准：协变量分布平衡的简便方法AI 解读

This paper proposes a~simple, yet powerful, method for balancing distributions of covariates for causal inference based on observational studies. The method makes it possible to balance an arbitrary number of quantiles (e.g., medians, quartiles, or deciles) together with means if necessary. The proposed approach is based on the theory of calibration estimators (Deville and Särndal 1992), in particular, calibration estimators for quantiles, proposed by Harms and Duchesne…

利用影子价格降低交易平台的市场干扰偏差AI 解读

Marketplace companies rely heavily on experimentation when making changes to the design or operation of their platforms. The workhorse of experimentation is the randomized controlled trial (RCT), or A/B test, in which users are randomly assigned to treatment or control groups. However, marketplace interference causes the Stable Unit Treatment Value Assumption (SUTVA) to be violated, leading to bias in the standard RCT metric. In this work, we propose techniques for platforms…