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GENIUS-MAWII：应对大量弱且无效工具变量的稳健孟德尔随机化AI 解读

Mendelian randomization (MR) has become a popular approach to study causal effects by using genetic variants as instrumental variables. We propose a new MR method, GENIUS-MAWII, which simultaneously addresses the two salient phenomena that adversely affect MR analyses: many weak instruments and widespread horizontal pleiotropy. Similar to MR GENIUS (Tchetgen Tchetgen et al., 2021), we achieve identification of the treatment effect by leveraging heteroscedasticity of the…

算法辅助人类决策的最优策略AI 解读

We consider optimal regimes for algorithm-assisted human decision-making. Such regimes are decision functions of measured pre-treatment variables and, by leveraging natural treatment values, enjoy a "superoptimality" property whereby they are guaranteed to outperform conventional optimal regimes. When there is unmeasured confounding, the benefit of using superoptimal regimes can be considerable. When there is no unmeasured confounding, superoptimal regimes are identical to…

具有多个接收者的关系事件潜变量模型AI 解读

Directional relational event data, such as email data, often contain unicast messages (i.e., messages of one sender towards one receiver) and multicast messages (i.e., messages of one sender towards multiple receivers). The Enron email data that is the focus in this paper consists of 31% multicast messages. Multicast messages contain important information about the roles of actors in the network, which is needed for better understanding social interaction dynamics. In this…

厘清整群随机试验中的估计目标AI 解读

Estimands can help clarify the interpretation of treatment effects and ensure that estimators are aligned to the study's objectives. Cluster randomised trials require additional attributes to be defined within the estimand compared to individually randomised trials, including whether treatment effects are marginal or cluster specific, and whether they are participant or cluster average. In this paper, we provide formal definitions of estimands encompassing both these…

通过逆协方差矩阵的稀疏分解学习大型因果结构AI 解读

Learning causal structures from observational data is a fundamental problem facing important computational challenges when the number of variables is large. In the context of linear structural equation models (SEMs), this paper focuses on learning causal structures from the inverse covariance matrix. The proposed method, called ICID for Independence-preserving Decomposition from Inverse Covariance matrix, is based on continuous optimization of a matrix decomposition model…

选择模型与置换不变性：差异化产品市场的需求估计AI 解读

Choice modeling is at the core of understanding how changes to the competitive landscape affect consumer choices and reshape market equilibria. In this paper, we propose a fundamental characterization of choice functions that encompasses a wide variety of extant choice models. We demonstrate how non-parametric estimators like neural nets can easily approximate such functionals and overcome the curse of dimensionality that is inherent in the non-parametric estimation of…

存在治疗不依从时构造最优策略的敏感性分析AI 解读

The current body of research on developing optimal treatment strategies often places emphasis on intention-to-treat analyses, which fail to take into account the compliance behavior of individuals. Methods based on instrumental variables have been developed to determine optimal treatment strategies in the presence of endogeneity. However, these existing methods are not applicable when there are two active treatment options and the average causal effects of the treatments…

利用 Bootstrap 集成与置信度度量改进时间序列因果发现AI 解读

Learning causal graphs from multivariate time series is a ubiquitous challenge in all application domains dealing with time-dependent systems, such as in Earth sciences, biology, or engineering, to name a few. Recent developments for this causal discovery learning task have shown considerable skill, notably the specific time-series adaptations of the popular conditional independence-based learning framework. However, uncertainty estimation is challenging for conditional…