每日简报

多变量孟德尔随机化的一种更稳健方法AI 解读

Multivariable Mendelian randomization (MVMR) uses genetic variants as instrumental variables to infer the direct effects of multiple exposures on an outcome. However, unlike univariable Mendelian randomization, MVMR often faces greater challenges with many weak instruments, which can lead to bias not necessarily toward zero and inflation of type I errors. In this work, we introduce a new asymptotic regime that allows exposures to have varying degrees of instrument strength,…

将大语言模型融入因果发现：统计因果方法AI 解读

In practical statistical causal discovery (SCD), embedding domain expert knowledge as constraints into the algorithm is important for reasonable causal models reflecting the broad knowledge of domain experts, despite the challenges in the systematic acquisition of background knowledge. To overcome these challenges, this paper proposes a novel method for causal inference, in which SCD and knowledge-based causal inference (KBCI) with a large language model (LLM) are…

重复结果结构嵌套均值模型中效应修饰变量选择的惩罚 G 估计AI 解读

Effect modification occurs when the impact of the treatment on an outcome varies based on the levels of other covariates known as effect modifiers. Modeling these effect differences is important for etiological goals and for purposes of optimizing treatment. Structural nested mean models (SNMMs) are useful causal models for estimating the potentially heterogeneous effect of a time-varying exposure on the mean of an outcome in the presence of time-varying confounding. A…

通过序贯调整混杂与样本流失恢复因果效应并开展推断AI 解读

Confounding bias and selection bias bring two significant challenges to the validity of conclusions drawn from applied causal inference. The latter can stem from informative missingness, such as in cases of attrition. We introduce the Sequential Adjustment Criteria (SAC), which extend available graphical conditions for recovering causal effects from confounding and attrition using sequential regressions, allowing for the inclusion of post-exposure and forbidden variables in…

DoubleMLDeep：利用多模态数据估计因果效应AI 解读

This paper explores the use of unstructured, multimodal data, namely text and images, in causal inference and treatment effect estimation. We propose a neural network architecture that is adapted to the double machine learning (DML) framework, specifically the partially linear model. An additional contribution of our paper is a new method to generate a semi-synthetic dataset which can be used to evaluate the performance of causal effect estimation in the presence of text and…

处理时变混杂的灵活贝叶斯生存分析 g 公式AI 解读

In longitudinal observational studies with time-to-event outcomes, a common objective in causal analysis is to estimate the causal survival curve under hypothetical intervention scenarios. The g-formula is a useful tool for this analysis. To enhance the traditional parametric g-formula, we developed an alternative g-formula estimator, which incorporates the Bayesian Additive Regression Trees (BART) into the modeling of the time-evolving generative components, aiming to…

结合 T-learning 与 DR-learning：因果对比的 oracle 有效估计框架AI 解读

We introduce efficient plug-in (EP) learning, a novel framework for the estimation of heterogeneous causal contrasts, such as the conditional average treatment effect and conditional relative risk. The EP-learning framework enjoys the same oracle efficiency as Neyman-orthogonal learning strategies, such as DR-learning and R-learning, while addressing some of their primary drawbacks: (i) their practical applicability can be hindered by non-convex loss functions; and (ii) they…

动态线性面板模型的 Arellano–Bond LASSO 估计量AI 解读

The Arellano-Bond estimator is a fundamental method for dynamic panel data models, widely used in practice. It can be severely biased when the time series dimension of the data, $T$, is long. The source of the bias is the large degree of overidentification. We propose a simple two-step approach to deal with this problem. The first step applies LASSO to the cross-section data at each time period to select the most informative moment conditions, exploiting the approximately…

基于高斯过程网络的贝叶斯因果推断AI 解读

Causal discovery and inference from observational data is an essential problem in statistics posing both modeling and computational challenges. These are typically addressed by imposing strict assumptions on the joint distribution such as linearity. We consider the problem of the Bayesian estimation of the effects of hypothetical interventions in the Gaussian Process Network (GPN) model, a flexible causal framework which allows describing the causal relationships…

分层随机实验中的锐方差估计与因果自助法AI 解读

Randomized experiments are the gold standard for estimating treatment effects, and randomization serves as a reasoned basis for inference. In widely used stratified randomized experiments, randomization-based finite-population asymptotic theory enables valid inference for the average treatment effect, relying on normal approximation and a Neyman-type conservative variance estimator. However, when the sample size is small or the outcomes are skewed, the Neyman-type variance…

图神经网络估计理论及其网络异质性应用AI 解读

This paper presents a novel application of graph neural networks for modeling and estimating network heterogeneity. Network heterogeneity is characterized by variations in unit's decisions or outcomes that depend not only on its own attributes but also on the conditions of its surrounding neighborhood. We delineate the convergence rate of the graph neural networks estimator, as well as its applicability in semiparametric causal inference with heterogeneous treatment effects.…

结果误报下二元选择模型的部分识别AI 解读

This paper provides partial identification of various binary choice models with misreported dependent variables. We propose two distinct approaches by exploiting different instrumental variables respectively. In the first approach, the instrument is assumed to only affect the true dependent variable but not misreporting probabilities. The second approach uses an instrument that influences misreporting probabilities monotonically while having no effect on the true dependent…

用于可解释因果效应估计的分层偏差驱动分层方法AI 解读

Interpretability and transparency are essential for incorporating causal effect models from observational data into policy decision-making. They can provide trust for the model in the absence of ground truth labels to evaluate the accuracy of such models. To date, attempts at transparent causal effect estimation consist of applying post hoc explanation methods to black-box models, which are not interpretable. Here, we present BICauseTree: an interpretable balancing method…

多项分布数据下排名的有限样本与大样本推断：政党排名应用AI 解读

It is common to rank different categories by means of preferences that are revealed through data on choices. A prominent example is the ranking of political candidates or parties using the estimated share of support each one receives in surveys or polls about political attitudes. Since these rankings are computed using estimates of the share of support rather than the true share of support, there may be considerable uncertainty concerning the true ranking of the political…

多重重复测量的多变量有序回归AI 解读

In this paper we propose a multivariate ordinal regression model which allows the joint modeling of three-dimensional panel data containing both repeated and multiple measurements for a collection of subjects. This is achieved by a multivariate autoregressive structure on the errors of the latent variables underlying the ordinal responses, where we distinguish between the correlations at a single point in time and the persistence over time. The error distribution is assumed…

因果面板模型矩阵补全方法中的数据驱动模型选择AI 解读

Matrix completion estimators are employed in causal panel data models to regulate the rank of the underlying factor model using nuclear norm minimization. This convex optimization problem enables concurrent regularization of a potentially high-dimensional set of covariates to shrink the model size. For valid finite sample inference, we adopt a permutation-based approach and prove its validity for any treatment assignment mechanism. Simulations illustrate the consistency of…

利用局部分布开展孟德尔随机化：不确定的意见无效AI 解读

Mendelian randomization (MR) considers using genetic variants as instrumental variables (IVs) to infer causal effects in observational studies. However, the validity of causal inference in MR can be compromised when the IVs are potentially invalid. In this work, we propose a new method, MR-Local, to infer the causal effect in the existence of possibly invalid IVs. By leveraging the distribution of ratio estimates around the true causal effect, MR-Local selects the cluster of…

分布一致性结构因果模型AI 解读

In the field of causal modeling, potential outcomes (PO) and structural causal models (SCMs) stand as the predominant frameworks. However, these frameworks face notable challenges in practically modeling counterfactuals, formalized as parameters of the joint distribution of potential outcomes. Counterfactual reasoning holds paramount importance in contemporary decision-making processes, especially in scenarios that demand personalized incentives based on the joint values of $(Y(0), Y(1))$…

利用替代结局估计连续处理效应AI 解读

In many real-world causal inference applications, the primary outcomes (labels) are often partially missing, especially if they are expensive or difficult to collect. If the missingness depends on covariates (i.e., missingness is not completely at random), analyses based on fully observed samples alone may be biased. Incorporating surrogates, which are fully observed post-treatment variables related to the primary outcome, can improve estimation in this case. In this paper,…

基于回归的近端因果推断AI 解读

Negative controls are increasingly used to evaluate the presence of potential unmeasured confounding in observational studies. Beyond the use of negative controls to detect the presence of residual confounding, proximal causal inference (PCI) was recently proposed to de-bias confounded causal effect estimates, by leveraging a pair of treatment and outcome negative control or confounding proxy variables. While formal methods for statistical inference have been developed for…

生存试验中治疗交叉分析的统一三状态模型框架AI 解读

We present a unified three-state model (TSM) framework for evaluating treatment effects in clinical trials in the presence of treatment crossover. Researchers have proposed diverse methodologies to estimate the treatment effect that would have hypothetically been observed if treatment crossover had not occurred. However, there is little work on understanding the connections between these different approaches from a statistical point of view. The proposed TSM framework…

利用共享神经元 RBF 网络估计个体化多处理响应曲线AI 解读

Heterogeneous treatment effect estimation is an important problem in precision medicine. Specific interests lie in identifying the differential effect of different treatments based on some external covariates. We propose a novel non-parametric treatment effect estimation method in a multi-treatment setting. Our non-parametric modeling of the response curves relies on radial basis function (RBF)-nets with shared hidden neurons. Our model thus facilitates modeling commonality…

费舍尔市场均衡与一价拍卖预算调节均衡的自助法推断AI 解读

The linear Fisher market (LFM) is a basic equilibrium model from economics, which also has applications in fair and efficient resource allocation. First-price pacing equilibrium (FPPE) is a model capturing budget-management mechanisms in first-price auctions. In certain practical settings such as advertising auctions, there is an interest in performing statistical inference over these models. A popular methodology for general statistical inference is the bootstrap procedure.…

具有分布目标的最优政策学习中的公平性正则化AI 解读

A decision maker typically (i) incorporates training data to learn about the relative effectiveness of treatments, and (ii) chooses an implementation mechanism that implies an ``optimal'' predicted outcome distribution according to some target functional. Nevertheless, a fairness-aware decision maker may not be satisfied achieving said optimality at the cost of being ``unfair" against a subgroup of the population, in the sense that the outcome distribution in that subgroup…