Modern approaches for evaluating treatment effect heterogeneity from clinical trials and observational data
评估临床试验与观察数据中处理效应异质性的现代方法
In this paper we review recent advances in statistical methods for the evaluation of the heterogeneity of treatment effects (HTE), including subgroup identification and estimation of individualized treatment regimens, from randomized clinical trials and observational studies. We identify several types of approaches using the features introduced in Lipkovich, Dmitrienko and D'Agostino (2017) that distinguish the recommended principled methods from basic methods for HTE…