论文检索

基于多元混合效应模型的动态共表达网络估计AI 解读

High-throughput sequencing technologies have enabled the collection of large-scale longitudinal -omics data, providing new opportunities for studying co-expression networks among molecular nodes such as genes and proteins. However, the high dimensionality and temporal dependence inherent in such data require specialized statistical methods. We propose a novel approach to infer dynamic co-expression networks among features over time (DCENt), where each node (feature) is…

使用 R 包 mets 分析生存与竞争风险数据的限制平均损失时间AI 解读

This paper introduces software implemented in the mets R-package for calculating non-parametric and regression estimates of Restricted Mean Survival Time (RMST) and Restricted Mean Time Lost (RMTL), including RMTL due to specific causes. A unique feature is the ability to compute the non-parametric estimates of RMST and RMTL, as well as their standard errors, for all time horizons simultaneously. Regression modeling in mets is based on Inverse Probability of Censoring…

面向复杂计算机模型的收缩约束函数标定AI 解读

We propose a new Bayesian model calibration formalism as an alternative to the Kennedy O'Hagan (KOH) framework which we term integrated bias with full uncertainty (IBFU). In KOH, calibration parameters are modeled as fixed, but unknown distributions with relatively weak prior constraints, and their posteriors are inferred jointly with an additive discrepancy Gaussian Process (GP). This formulation often provides limited regularization and leads to confounding pathologies…

通过矩阵补全改进异质性处理效应估计的理论保证AI 解读

A central goal of modern causal inference is estimating heterogeneous treatment effects to answer questions like "how does an intervention affect each unit," rather than only on average. We study this problem with panel-data where we observe $n$ units across $m$ times under unknown, non-uniform treatment assignments. The data in this setting is naturally represented as a matrix of all unit--time treatment effects. Estimating heterogeneous treatment effects can then be…

高维数据中的测量误差：惩罚回归方法综述与比较AI 解读

In many important statistical analyses, the number of covariates $p$ often exceeds the data size $n$, a regime commonly referred to as high-dimensional. While considerable progress has been made in high-dimensional regression under the assumption of error-free covariates, real-world data frequently involve noisy or corrupted measurements. When left unaddressed, measurement errors can silently distort the analysis and mislead the conclusions. This paper reviews and evaluates…

函数型结局因果效应的半参数推断AI 解读

Difference-in-differences (DiD) is a cornerstone of causal inference, yet extending it to functional outcomes is not a routine scalar generalization; rather, it entails three fundamental challenges in identification, inference, and observation. This paper develops a comprehensive semiparametric inference framework for functional DiD with discretely observed data. First, we define the functional average treatment effect under parallel trends and derive its efficient influence…

凸成对差分估计量的稳健推断AI 解读

This paper develops distribution theory and bootstrap-based inference methods for a broad class of convex pairwise difference estimators. These estimators minimize a kernel-weighted convex-in-parameter function over observation pairs with similar covariates, where the similarity is governed by a localization (bandwidth) parameter. While classical results establish asymptotic normality under restrictive bandwidth conditions, we show that valid Gaussian and bootstrap-based…

修改因果模型以区分暂时与持久的因果效应AI 解读

This paper considers how to classify the effects of interventions in causal models for outcomes and exposures observed over time. First, we demonstrate the limitations of the most common uses of potential outcomes and causal directed acyclic graphs for capturing all possible interventions in a time varying framework, particularly in problems where the key question concerns interventions to maintain or change equilibrium behaviour. Second, we adopt a system and state based…

序贯非单调缺失下的双重稳健 GMM 估计量AI 解读

We study moment-based estimation with two sequentially collected variables subject to non-monotone missingness. The commonly used Missing at Random (MAR) assumption requiring all missingness mechanisms to depend on the same fully observed covariates often fails in such cases. We introduce a sequential MAR assumption that allows asymmetric missingness mechanisms across stages. Based on this assumption, we construct an Augmented Inverse-Probability-Weighted GMM (AIPW-GMM)…

拓扑稳定性指数：持久条形码的方差度量AI 解读

We introduce the \emph{Topological Stability Index} (TSI), a variance-based scalar measure for persistence barcodes that quantifies the dispersion of persistence lifetimes. Unlike persistent entropy, which depends only on normalized weights, the TSI captures absolute variability and is sensitive to heterogeneous feature scales. We establish fundamental properties of the TSI, including its scaling behavior, invariance under lifetime translation and explicit update formulas…

函数型自回归模型的拟合优度检验AI 解读

The proposed Goodness--of--Fit (GoF) test for checking the linear autocorrelation model in a functional time series is based on an empirical process, whose residual marks and covariate index set are in a separable Hilbert space \mathbb{H}. A functional central limit theorem is derived providing the convergence of the empirical process to a time-changed Wiener process evaluated in a separable Hilbert space \mathbb{H}, with subordinator given by the marginal probability of the…

rd2d：边界断点设计中的因果推断软件AI 解读

Boundary Discontinuity (BD) designs are used in empirical research to learn about causal treatment effects along a continuous assignment boundary defined by a bivariate score. These designs are also known as multi-score regression discontinuity (RD) designs, and include geographic RD designs as a prominent example. This article introduces \pkg{rd2d}, a statistical software package for \proglang{R}, \proglang{Python}, and \proglang{Stata} that implements local polynomial…

高斯—柯西卷积模型的精确似然推断与稳健滤波AI 解读

The convolution of a Gaussian and a Cauchy distribution, known as the Voigt distribution, is widely used in spectroscopy and provides a natural framework for modeling heavy-tailed measurement noise. We derive analytical expressions for its density, score, Hessian, Fisher information, and conditional moments using the scaled complementary error function, enabling stable maximum likelihood estimation without numerical convolution, finite-difference derivatives, or pseudo-Voigt…

层级预测中信息的作用AI 解读

In hierarchical forecasting, the process of forecast reconciliation transforms a set of "base" or "raw" forecasts, which do not satisfy the hierarchical aggregation constraints in the real data, into a set of "coherent" forecasts, which do satisfy those constraints. The academic literature provides ample simulation evidence and real-world examples demonstrating the value of forecast reconciliation in improving forecasts of hierarchical time series. This improvement is…

连接最大似然与最优传输：随机块模型的高效推断与模型选择AI 解读

We study inference in stochastic block models (SBMs) through the lens of optimal transport (OT). We first establish that maximum likelihood variational inference (MLVI) can be interpreted as a semi-relaxed Gromov-Wasserstein (srGW) projection with entropic regularization. While this formulation yields accurate clustering, the entropic regularization prevents transport plans to be sparse, hindering intrinsic model selection. Consequently, we investigate unregularized srGW…

基于 Copula 马尔可夫模型的 Weibull 时间序列变点估计AI 解读

We study offline change-point estimation for time series data exhibiting nonlinear serial dependence. To address this problem, we propose a copula-based Markov chain model with Weibull marginal distributions, which is suitable for modeling nonnegative data such as event times and volatility measures. Nonlinear dependence is incorporated through the Clayton and Joe copulas, allowing the model to capture asymmetric lower-tail and upper-tail dependence structures, respectively.…

利用两阶段核岭回归估计连续处理效应AI 解读

We study the problem of estimating the effect function for a continuous treatment, which maps each treatment value to a population-averaged outcome. A central challenge in this setting is confounding: treatment assignment often depends on covariates, creating selection bias that makes direct regression of the response on treatment unreliable. To address this issue, we propose a two-stage kernel ridge regression method. In the first stage, we learn a model for the response as…

采用样本分割的广义谱检验AI 解读

Residual-based goodness-of-fit tests for parametric time-series models are often complicated by parameter-estimation effects, which can alter the limiting behavior of diagnostic statistics. We propose a sample-splitting generalized spectral test (in the spirit of Escanciano(2006)) for assessing conditional mean specification in linear and nonlinear time-series models. The procedure estimates the model parameter on a fitting subsample and constructs a generalized spectral…

利用工具变量交互识别与推断结构加速失效时间模型AI 解读

We study causal inference for time-to-event outcomes under right censoring in the presence of unmeasured confounding. Focusing on structural accelerated failure time models, we develop an identification and inference framework that exploits interactions among instrumental variables. The proposed approach does not rely on classical instrumental variable validity and yields valid causal inference under both valid and invalid instruments, provided that the interaction-based…

结果校准回归与基于预测结果的推断AI 解读

Regression is a fundamental tool in scientific research. Ordinary least squares (OLS), one of the most widely used regression methods, enjoys several desirable properties, including the best linear unbiased estimator (BLUE) property. It is well known that, under the assumptions of the standard model, the OLS is conditionally unbiased given the covariates, i.e., $\mathbb{E}(\widehat Y-Y\mid X=x)=0$. However, an often-overlooked property of OLS is that the prediction error is…

网络混杂下基于图神经网络的广义 Mundlak 估计量AI 解读

This paper proposes a generalized Mundlak estimator based on graph neural networks (GME-GNN). The estimator is designed to mitigate bias arising from group-level heterogeneity and to accommodate within-group dependence among individuals. Traditional fixed-effects models handle group heterogeneity via group-specific intercepts, but require overly strict linear additivity and intra-group independence assumptions, and are confined to within-group comparisons. Rather than…

随机饱和度设计中簇内与簇间溢出效应的估计AI 解读

Randomized saturation designs are two-stage experiments: they first randomly assign treatment probabilities over the clusters and then randomly assign the treatment to the units within the clusters. The existing literature on randomized saturation designs focuses on estimating within-cluster spillover effects by assuming away between-cluster spillover effects. However, the units may interact across clusters in many practical randomized saturation designs. A leading example…

超越准确率：时间序列基础模型是否校准良好？AI 解读

The recent development of foundation models for time series data has generated considerable interest in using such models across a variety of applications. Although foundation models achieve state-of-the-art predictive performance, their calibration properties remain relatively underexplored, despite the fact that calibration can be critical for many practical applications. In this paper, we investigate the calibration-related properties of five recent time series foundation…

含未观测混杂因素的贝叶斯结构化中介分析AI 解读

We explore methods to reduce the impact of unobserved confounders on the causal mediation analysis of high-dimensional mediators with spatially smooth structures, such as brain imaging data. The key approach is to incorporate the latent individual effects, which influence the structured mediators, as unobserved confounders in the outcome model, thereby potentially debiasing the mediation effects. We develop BAyesian Structured Mediation analysis with Unobserved confounders…