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Treatment Choice, Mean Square Regret and Partial Identification

处理选择、均方遗憾与部分识别

We consider a decision maker who faces a binary treatment choice when their welfare is only partially identified from data. We contribute to the literature by anchoring our finite-sample analysis on mean square regret, a decision criterion advocated by Kitagawa, Lee, and Qiu (2022). We find that optimal rules are always fractional, irrespective of the width of the identified set and precision of its estimate. The optimal treatment fraction is a simple logistic transformation…

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Learning domain-specific causal discovery from time series

从时间序列学习领域特定的因果发现方法

Causal discovery (CD) from time-varying data is important in neuroscience, medicine, and machine learning. Techniques for CD encompass randomized experiments, which are generally unbiased but expensive, and algorithms such as Granger causality, conditional-independence-based, structural-equation-based, and score-based methods that are only accurate under strong assumptions made by human designers. However, as demonstrated in other areas of machine learning, human expertise…

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Spectral norm bounds for high-dimensional realized covariance matrices and application to weak factor models

高维已实现协方差矩阵的谱范数界及弱因子模型应用

Motivated by statistical analysis of latent factor models for high-frequency financial data, we develop sharp upper bounds for the spectral norm of the realized covariance matrix of a high-dimensional Itô semimartingale with possibly infinite activity jumps. For this purpose, we develop Burkholder-Gundy type inequalities for matrix martingales with the help of the theory of non-commutative $L^p$ spaces. The obtained bounds are applied to estimating the number of (relevant)…

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SURE-tuned Bridge Regression

SURE 调参的 Bridge 回归

Consider the {$\ell_α$} regularized linear regression, also termed Bridge regression. For $α\in (0,1)$, Bridge regression enjoys several statistical properties of interest such as sparsity and near-unbiasedness of the estimates (Fan and Li, 2001). However, the main difficulty lies in the non-convex nature of the penalty for these values of $α$, which makes an optimization procedure challenging and usually it is only possible to find a local optimum. To address this issue,…

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Robust Minimum Distance Inference in Structural Models

结构模型中的稳健最小距离推断

This paper proposes minimum distance inference for a structural parameter of interest, which is robust to the lack of identification of other structural nuisance parameters. Some choices of the weighting matrix lead to asymptotic chi-squared distributions with degrees of freedom that can be consistently estimated from the data, even under partial identification. In any case, knowledge of the level of under-identification is not required. We study the power of our robust…

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A neutral comparison of statistical methods for time-to-event analyses under non-proportional hazards

非比例风险下生存分析统计方法的中立比较

While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best inferential approach under non-proportional hazards (NPH). However, a wide range of parametric and non-parametric methods for testing and estimation in this scenario have been proposed. To provide recommendations on the statistical analysis of clinical trials where non proportional hazards are expected, we conducted a…

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Projecting infinite time series graphs to finite marginal graphs using number theory

用数论将无限时间序列图投影为有限边际图

In recent years, a growing number of method and application works have adapted and applied the causal-graphical-model framework to time series data. Many of these works employ time-resolved causal graphs that extend infinitely into the past and future and whose edges are repetitive in time, thereby reflecting the assumption of stationary causal relationships. However, most results and algorithms from the causal-graphical-model framework are not designed for infinite graphs.…

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On the mixed-model analysis of covariance in cluster-randomized trials

整群随机试验中的混合模型协方差分析

In the analyses of cluster-randomized trials, mixed-model analysis of covariance (ANCOVA) is a standard approach for covariate adjustment and handling within-cluster correlations. However, when the normality, linearity, or the random-intercept assumption is violated, the validity and efficiency of the mixed-model ANCOVA estimators for estimating the average treatment effect remain unclear. Under the potential outcomes framework, we prove that the mixed-model ANCOVA…

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Identification and Estimation in a Class of Potential Outcomes Models

一类潜在结果模型的识别与估计

This paper develops a class of potential outcomes models characterized by three main features: (i) Unobserved heterogeneity can be represented by a vector of potential outcomes and a type describing the manner in which an instrument determines the choice of treatment; (ii) The availability of an instrumental variable that is conditionally independent of unobserved heterogeneity; and (iii) The imposition of convex restrictions on the distribution of unobserved heterogeneity.…

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Estimating the minimizer and the minimum value of a regression function under passive design

被动设计下回归函数最小值点与最小值的估计

We propose a new method for estimating the minimizer $\boldsymbol{x}^*$ and the minimum value $f^*$ of a smooth and strongly convex regression function $f$ from the observations contaminated by random noise. Our estimator $\boldsymbol{z}_n$ of the minimizer $\boldsymbol{x}^*$ is based on a version of the projected gradient descent with the gradient estimated by a regularized local polynomial algorithm. Next, we propose a two-stage procedure for estimation of the minimum…

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Constructing High Frequency Economic Indicators by Imputation

通过插补构建高频经济指标

Monthly and weekly economic indicators are often taken to be the largest common factor estimated from high and low frequency data, either separately or jointly. To incorporate mixed frequency information without directly modeling them, we target a low frequency diffusion index that is already available, and treat high frequency values as missing. We impute these values using multiple factors estimated from the high frequency data. In the empirical examples considered, static…

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Learning and scoring Gaussian latent variable causal models with unknown additive interventions

未知加性干预下高斯潜变量因果模型的学习与评分

With observational data alone, causal structure learning is a challenging problem. The task becomes easier when having access to data collected from perturbations of the underlying system, even when the nature of these is unknown. Existing methods either do not allow for the presence of latent variables or assume that these remain unperturbed. However, these assumptions are hard to justify if the nature of the perturbations is unknown. We provide results that enable scoring…

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Modern Non-Linear Function-on-Function Regression

现代非线性函数型-函数型回归

We introduce a new class of non-linear function-on-function regression models for functional data using neural networks. We propose a framework using a hidden layer consisting of continuous neurons, called a continuous hidden layer, for functional response modeling and give two model fitting strategies, Functional Direct Neural Network (FDNN) and Functional Basis Neural Network (FBNN). Both are designed explicitly to exploit the structure inherent in functional data and…

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Identifying regime switches through Bayesian wavelet estimation: evidence from flood detection in the Taquari River Valley

通过贝叶斯小波估计识别状态切换:塔夸里河谷洪水检测

Two-component mixture models have proved to be a powerful tool for modeling heterogeneity in several cluster analysis contexts. However, most methods based on these models assume a constant behavior for the mixture weights, which can be restrictive and unsuitable for some applications. In this paper, we relax this assumption and allow the mixture weights to vary according to the index (e.g., time) to make the model more adaptive to a broader range of data sets. We propose an…

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On changepoint detection in functional data using empirical energy distance

利用经验能量距离检测函数型数据的变点

We propose a novel family of test statistics to detect the presence of changepoints in a sequence of dependent, possibly multivariate, functional-valued observations. Our approach allows to test for a very general class of changepoints, including the "classical" case of changes in the mean, and even changes in the whole distribution. Our statistics are based on a generalisation of the empirical energy distance; we propose weighted functionals of the energy distance process,…

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Estimating marginal treatment effects from observational studies and indirect treatment comparisons: When are standardization-based methods preferable to those based on propensity score weighting?

边际处理效应估计:何时标准化优于倾向得分加权?

In light of newly developed standardization methods, we evaluate, via simulation study, how propensity score weighting and standardization -based approaches compare for obtaining estimates of the marginal odds ratio and the marginal hazard ratio. Specifically, we consider how the two approaches compare in two different scenarios: (1) in a single observational study, and (2) in an anchored indirect treatment comparison (ITC) of randomized controlled trials. We present the…

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Time-dependent mediators in survival analysis: Graphical representation of causal assumptions

生存分析中的时变中介:因果假设的图形表示

We study time-dependent mediators in survival analysis using a treatment separation approach due to Didelez [2019] and based on earlier work by Robins and Richardson [2011]. This approach avoids nested counterfactuals and crossworld assumptions which are otherwise common in mediation analysis. The causal model of treatment, mediators, covariates, confounders and outcome is represented by causal directed acyclic graphs (DAGs). However, the DAGs tend to be very complex when we…

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Sparse high-dimensional linear regression with a partitioned empirical Bayes ECM algorithm

带分区经验贝叶斯 ECM 算法的稀疏高维线性回归

Bayesian variable selection methods are powerful techniques for fitting and inferring on sparse high-dimensional linear regression models. However, many are computationally intensive or require restrictive prior distributions on model parameters. In this paper, we proposed a computationally efficient and powerful Bayesian approach for sparse high-dimensional linear regression. Minimal prior assumptions on the parameters are required through the use of plug-in empirical Bayes…

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Asymptotics of the Sketched Pseudoinverse

随机草图伪逆的渐近理论

We take a random matrix theory approach to random sketching and show an asymptotic first-order equivalence of the regularized sketched pseudoinverse of a positive semidefinite matrix to a certain evaluation of the resolvent of the same matrix. We focus on real-valued regularization and extend previous results on an asymptotic equivalence of random matrices to the real setting, providing a precise characterization of the equivalence even under negative regularization,…

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Robust inference with GhostKnockoffs in genome-wide association studies

全基因组关联研究中 GhostKnockoffs 的稳健推断

Genome-wide association studies (GWASs) have been extensively adopted to depict the underlying genetic architecture of complex diseases. Motivated by GWASs' limitations in identifying small effect loci to understand complex traits' polygenicity and fine-mapping putative causal variants from proxy ones, we propose a knockoff-based method which only requires summary statistics from GWASs and demonstrate its validity in the presence of relatedness. We show that GhostKnockoffs…

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Ultimate limit on learning non-Markovian behavior: Fisher information rate and excess information

学习非马尔可夫行为的极限:费舍尔信息率与超额信息

We address the fundamental limits of learning unknown parameters of any stochastic process from time-series data, and discover exact closed-form expressions for how optimal inference scales with observation length. Given a parametrized class of candidate models, the Fisher information of observed sequence probabilities lower-bounds the variance in model estimation from finite data. As sequence-length increases, the minimal variance scales as the square inverse of the length…

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Conformal Inference for Online Prediction with Arbitrary Distribution Shifts

任意分布漂移下在线预测的保形推断

We consider the problem of forming prediction sets in an online setting where the distribution generating the data is allowed to vary over time. Previous approaches to this problem suffer from over-weighting historical data and thus may fail to quickly react to the underlying dynamics. Here we correct this issue and develop a novel procedure with provably small regret over all local time intervals of a given width. We achieve this by modifying the adaptive conformal…

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Federated Adaptive Causal Estimation (FACE) of Target Treatment Effects

目标人群处理效应的联邦自适应因果估计(FACE)

Federated learning of causal estimands may greatly improve estimation efficiency by leveraging data from multiple study sites, but robustness to heterogeneity and model misspecifications is vital for ensuring validity. We develop a Federated Adaptive Causal Estimation (FACE) framework to incorporate heterogeneous data from multiple sites to provide treatment effect estimation and inference for a flexibly specified target population of interest. FACE accounts for site-level…

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Characterization of causal ancestral graphs for time series with latent confounders

含潜在混杂的时间序列因果祖先图刻画

In this paper, we introduce a novel class of graphical models for representing time lag specific causal relationships and independencies of multivariate time series with unobserved confounders. We completely characterize these graphs and show that they constitute proper subsets of the currently employed model classes. As we show, from the novel graphs one can thus draw stronger causal inferences -- without additional assumptions. We further introduce a graphical…

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