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Exposure Effects on Count Outcomes with Observational Data, with Application to Incarcerated Women

观察数据中暴露对计数结果的效应:以被监禁女性为例

Causal inference methods can be applied to estimate the effect of a point exposure or treatment on an outcome of interest using data from observational studies. For example, in the Women's Interagency HIV Study, it is of interest to understand the effects of incarceration on the number of sexual partners and the number of cigarettes smoked after incarceration. In settings like this where the outcome is a count, the estimand is often the causal mean ratio, i.e., the ratio of…

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A Ridge-Regularised Jackknifed Anderson-Rubin Test

岭正则化的刀切 Anderson–Rubin 检验

We consider hypothesis testing in instrumental variable regression models with few included exogenous covariates but many instruments -- possibly more than the number of observations. We show that a ridge-regularised version of the jackknifed Anderson Rubin (1949, henceforth AR) test controls asymptotic size in the presence of heteroskedasticity, and when the instruments may be arbitrarily weak. Asymptotic size control is established under weaker assumptions than those…

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Graphical tools for selecting conditional instrumental sets

选择条件工具变量集合的图形工具

We consider the efficient estimation of total causal effects in the presence of unmeasured confounding using conditional instrumental sets. Specifically, we consider the two-stage least squares estimator in the setting of a linear structural equation model with correlated errors that is compatible with a known acyclic directed mixed graph. To set the stage for our results, we characterize the class of linearly valid conditional instrumental sets that yield consistent…

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Estimation and inference for transfer learning with high-dimensional quantile regression

高维分位数回归中的迁移学习估计与推断

Transfer learning has become an essential technique to exploit information from the source domain to boost performance of the target task. Despite the prevalence in high-dimensional data, heterogeneity and heavy tails are insufficiently accounted for by current transfer learning approaches and thus may undermine the resulting performance. We propose a transfer learning procedure in the framework of high-dimensional quantile regression models to accommodate heterogeneity and…

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Optimal Treatment Allocation for Efficient Policy Evaluation in Sequential Decision Making

序贯决策中用于高效政策评估的最优处理分配

A/B testing is critical for modern technological companies to evaluate the effectiveness of newly developed products against standard baselines. This paper studies optimal designs that aim to maximize the amount of information obtained from online experiments to estimate treatment effects accurately. We propose three optimal allocation strategies in a dynamic setting where treatments are sequentially assigned over time. These strategies are designed to minimize the variance…

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Identification of time-varying counterfactual parameters in nonlinear panel models

非线性面板模型中时变反事实参数的识别

We develop a general framework for the identification of counterfactual parameters in a class of nonlinear semiparametric panel models with fixed effects and time effects. Our method applies to models for discrete outcomes (e.g., two-way fixed effects binary choice) or continuous outcomes (e.g., censored regression), with discrete or continuous regressors. Our results do not require parametric assumptions on the error terms or time-homogeneity on the outcome equation. Our…

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Regularised optimal self-transport is approximate Gaussian mixture maximum likelihood

正则化最优自传输近似高斯混合模型极大似然

We investigate the link between regularised self-transport problems and maximum likelihood estimation in Gaussian mixture models (GMM). This link suggests that self-transport followed by a clustering technique leads to principled estimators at a reasonable computational cost. Also, robustness, sparsity and stability properties of the optimal transport plan arguably make the regularised self-transport a statistical tool of choice for the GMM.

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Detecting hidden confounding in observational data using multiple environments

利用多个环境的观测数据检测隐藏混杂

A common assumption in causal inference from observational data is that there is no hidden confounding. Yet it is, in general, impossible to verify this assumption from a single dataset. Under the assumption of independent causal mechanisms underlying the data-generating process, we demonstrate a way to detect unobserved confounders when having multiple observational datasets coming from different environments. We present a theory for testable conditional independencies that…

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Pooled Bewley Estimator of Long Run Relationships in Dynamic Heterogenous Panels

动态异质面板长期关系的合并 Bewley 估计量

Using a transformation of the autoregressive distributed lag model due to Bewley, a novel pooled Bewley (PB) estimator of long-run coefficients for dynamic panels with heterogeneous short-run dynamics is proposed. The PB estimator is directly comparable to the widely used Pooled Mean Group (PMG) estimator, and is shown to be consistent and asymptotically normal. Monte Carlo simulations show good small sample performance of PB compared to the existing estimators in the…

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Robust Parameter Estimation for the Lee-Carter Family: A Probabilistic Principal Component Approach

Lee–Carter 模型族的稳健参数估计:概率主成分方法

The well-known Lee-Carter model uses a bilinear form $\log(m_{x,t})=a_x+b_xk_t$ to represent the log mortality rate and has been widely researched and developed over the past thirty years. However, there has been little attention being paid to the robustness of the parameters against outliers, especially when estimating $b_x$. In response, we propose a robust estimation method for a wide family of Lee-Carter-type models, treating the problem as a Probabilistic Principal…

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High Precision Causal Model Evaluation with Conditional Randomization

条件随机化下的高精度因果模型评估

The gold standard for causal model evaluation involves comparing model predictions with true effects estimated from randomized controlled trials (RCT). However, RCTs are not always feasible or ethical to perform. In contrast, conditionally randomized experiments based on inverse probability weighting (IPW) offer a more realistic approach but may suffer from high estimation variance. To tackle this challenge and enhance causal model evaluation in real-world conditional…

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The use of restricted mean survival time to estimate treatment effect under model misspecification, a simulation study

模型误设下利用限制平均生存时间估计治疗效应:模拟研究

The use of the non-parametric Restricted Mean Survival Time endpoint (RMST) has grown in popularity as trialists look to analyse time-to-event outcomes without the restrictions of the proportional hazards assumption. In this paper, we evaluate the power and type I error rate of the parametric and non-parametric RMST estimators when treatment effect is explained by multiple covariates, including an interaction term. Utilising the RMST estimator in this way allows the combined…

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Sketching for Convex and Nonconvex Regularized Least Squares with Sharp Guarantees

凸与非凸正则化最小二乘的草图算法及其精确保证

Randomized algorithms are important for solving large-scale optimization problems. In this paper, we propose a fast sketching algorithm for least square problems regularized by convex or nonconvex regularization functions, Sketching for Regularized Optimization (SRO). Our SRO algorithm first generates a sketch of the original data matrix, then solves the sketched problem. Different from existing randomized algorithms, our algorithm handles general Frechet subdifferentiable…

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Causal inference with Machine Learning-Based Covariate Representation

基于机器学习协变量表示的因果推断

Utilizing covariate information has been a powerful approach to improve the efficiency and accuracy for causal inference, which support massive amount of randomized experiments run on data-driven enterprises. However, state-of-art approaches can become practically unreliable when the dimension of covariate increases to just 50, whereas experiments on large platforms can observe even higher dimension of covariate. We propose a machine-learning-assisted covariate…

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Proportional Response: Contextual Bandits for Simple and Cumulative Regret Minimization

比例响应:兼顾简单遗憾与累积遗憾的上下文老虎机

In many applications, e.g. in healthcare and e-commerce, the goal of a contextual bandit may be to learn an optimal treatment assignment policy at the end of the experiment. That is, to minimize simple regret. However, this objective remains understudied. We propose a new family of computationally efficient bandit algorithms for the stochastic contextual bandit setting, where a tuning parameter determines the weight placed on cumulative regret minimization (where we…

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Phase transitions in nonparametric regressions

非参数回归中的相变

When the unknown regression function of a single variable is known to have derivatives up to the $(γ+1)$th order bounded in absolute values by a common constant everywhere or a.e. (i.e., $(γ+1)$th degree of smoothness), the minimax optimal rate of the mean integrated squared error (MISE) is stated as $\left(\frac{1}{n}\right)^{\frac{2γ+2}{2γ+3}}$ in the literature. This paper shows that: (i) if $n\leq\left(γ+1\right)^{2γ+3}$, the minimax optimal MISE rate is $\frac{\log n}{n\log(\log n)}$…

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Inference for Matched Tuples and Fully Blocked Factorial Designs

匹配元组与完全区组析因设计的统计推断

This paper studies inference in randomized controlled trials with multiple treatments, where treatment status is determined according to a "matched tuples" design. Here, by a matched tuples design, we mean an experimental design where units are sampled i.i.d. from the population of interest, grouped into "homogeneous" blocks with cardinality equal to the number of treatments, and finally, within each block, each treatment is assigned exactly once uniformly at random. We…

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Comparison of methods for analyzing environmental mixtures effects on survival outcomes and application to a population-based cohort study

环境混合暴露对生存结局影响的分析方法比较及人群队列应用

The estimation of the effect of environmental exposures and overall mixtures on a survival time outcome is common in environmental epidemiological studies. While advanced statistical methods are increasingly being used for mixture analyses, their applicability and performance for survival outcomes has yet to be explored. We identified readily available methods for analyzing an environmental mixture's effect on a survival outcome and assessed their performance via simulations…

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Kernel-based Joint Independence Tests for Multivariate Stationary and Non-stationary Time Series

多变量平稳与非平稳时间序列的核联合独立性检验

Multivariate time series data that capture the temporal evolution of interconnected systems are ubiquitous in diverse areas. Understanding the complex relationships and potential dependencies among co-observed variables is crucial for the accurate statistical modelling and analysis of such systems. Here, we introduce kernel-based statistical tests of joint independence in multivariate time series by extending the $d$-variable Hilbert-Schmidt independence criterion (dHSIC) to…

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Scalable Counterfactual Distribution Estimation in Multivariate Causal Models

多变量因果模型中可扩展的反事实分布估计

We consider the problem of estimating the counterfactual joint distribution of multiple quantities of interests (e.g., outcomes) in a multivariate causal model extended from the classical difference-in-difference design. Existing methods for this task either ignore the correlation structures among dimensions of the multivariate outcome by considering univariate causal models on each dimension separately and hence produce incorrect counterfactual distributions, or poorly…

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Inference on the intraday spot volatility from high-frequency order prices with irregular microstructure noise

不规则微观结构噪声下基于高频订单价格的日内瞬时波动率推断

We consider estimation of the spot volatility in a stochastic boundary model with one-sided microstructure noise for high-frequency limit order prices. Based on discrete, noisy observations of an Itô semimartingale with jumps and general stochastic volatility, we present a simple and explicit estimator using local order statistics. We establish consistency and stable central limit theorems as asymptotic properties. The asymptotic analysis builds upon an expansion of tail…

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Personalized Assignment to One of Many Treatment Arms via Regularized and Clustered Joint Assignment Forests

通过正则化与聚类联合分配森林实现多处理臂个性化分配

We consider learning personalized assignments to one of many treatment arms from a randomized controlled trial. Standard methods that estimate heterogeneous treatment effects separately for each arm may perform poorly in this case due to excess variance. We instead propose methods that pool information across treatment arms: First, we consider a regularized forest-based assignment algorithm based on greedy recursive partitioning that shrinks effect estimates across arms.…

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Inferring Stochastic Group Interactions within Structured Populations via Coupled Autoregression

通过耦合自回归推断结构化种群中的随机群体互动

The internal behaviour of a population is an important feature to take account of when modelling their dynamics. In line with kin selection theory, many social species tend to cluster into distinct groups in order to enhance their overall population fitness. Temporal interactions between populations are often modelled using classical mathematical models, but these sometimes fail to delve deeper into the, often uncertain, relationships within populations. Here, we introduce a…

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On Learning Necessary and Sufficient Causal Graphs

必要且充分因果图的学习

The causal revolution has stimulated interest in understanding complex relationships in various fields. Most of the existing methods aim to discover causal relationships among all variables within a complex large-scale graph. However, in practice, only a small subset of variables in the graph are relevant to the outcomes of interest. Consequently, causal estimation with the full causal graph -- particularly given limited data -- could lead to numerous falsely discovered,…

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