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Measuring Diagnostic Test Performance Using Imperfect Reference Tests: A Partial Identification Approach

不完美参照检测下诊断性能的部分识别

Diagnostic tests are almost never perfect. Studies quantifying their performance use knowledge of the true health status, measured with a reference diagnostic test. Researchers commonly assume that the reference test is perfect, which is often not the case in practice. When the assumption fails, conventional studies identify "apparent" performance or performance with respect to the reference, but not true performance. This paper provides the smallest possible bounds on the…

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Branch and Bound to Assess Stability of Regression Coefficients in Uncertain Models

用分支定界法评估不确定模型中回归系数的稳定性

It can be difficult to interpret a coefficient of an uncertain model. A slope coefficient of a regression model may change as covariates are added or removed from the model. In the context of high-dimensional data, there are too many model extensions to check. However, as we show here, it is possible to efficiently search, with a branch and bound algorithm, for maximum and minimum values of that adjusted slope coefficient over a discrete space of regularized regression…

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Deep Learning for the Estimation of Heterogeneous Parameters in Discrete Choice Models

离散选择模型异质参数估计中的深度学习

This paper studies the finite sample performance of the flexible estimation approach of Farrell, Liang, and Misra (2021a), who propose to use deep learning for the estimation of heterogeneous parameters in economic models, in the context of discrete choice models. The approach combines the structure imposed by economic models with the flexibility of deep learning, which assures the interpretebility of results on the one hand, and allows estimating flexible functional forms…

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Off-policy Evaluation in Doubly Inhomogeneous Environments

时间与个体双重异质环境中的离策略评估

This work aims to study off-policy evaluation (OPE) under scenarios where two key reinforcement learning (RL) assumptions -- temporal stationarity and individual homogeneity are both violated. To handle the ``double inhomogeneities", we propose a class of latent factor models for the reward and observation transition functions, under which we develop a general OPE framework that consists of both model-based and model-free approaches. To our knowledge, this is the first paper…

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An exhaustive selection of sufficient adjustment sets for causal inference

因果推断中充分调整集的穷尽选择

A subvector of predictor that satisfies the ignorability assumption, whose index set is called a sufficient adjustment set, is crucial for conducting reliable causal inference based on observational data. In this paper, we propose a general family of methods to detect all such sets for the first time in the literature, with no parametric assumptions on the outcome models and with flexible parametric and semiparametric assumptions on the predictor within the treatment groups;…

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Ridge detection for nonstationary multicomponent signals with time-varying wave-shape functions and its applications

时变波形多分量非平稳信号的脊线检测及其应用

We introduce a novel ridge detection algorithm for time-frequency (TF) analysis, particularly tailored for intricate nonstationary time series encompassing multiple non-sinusoidal oscillatory components. The algorithm is rooted in the distinctive geometric patterns that emerge in the TF domain due to such non-sinusoidal oscillations. We term this method \textit{shape-adaptive mode decomposition-based multiple harmonic ridge detection} (\textsf{SAMD-MHRD}). A swift…

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Method of Moments Estimation for Affine Stochastic Volatility Models

仿射随机波动率模型的矩估计

We develop moment estimators for the parameters of affine stochastic volatility models. We first address the challenge of calculating moments for the models by introducing a recursive equation for deriving closed-form expressions for moments of any order. Consequently, we propose our moment estimators. We then establish a central limit theorem for our estimators and derive the explicit formulas for the asymptotic covariance matrix. Finally, we provide numerical results to…

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On Doubly Robust Estimation with Nonignorable Missing Data Using Instrumental Variables

利用工具变量处理不可忽略缺失的双重稳健估计

Suppose we are interested in the mean of an outcome that is subject to nonignorable nonresponse. This paper develops new semiparametric estimation methods with instrumental variables which affect nonresponse, but not the outcome. The proposed estimators remain consistent and asymptotically normal even under partial model misspecifications for two variation independent nuisance components. We evaluate the performance of the proposed estimators via a simulation study, and…

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Augmented Binary Method for Basket Trials (ABBA)

篮式试验的增强二元方法(ABBA)

In several clinical areas, traditional clinical trials often use a responder outcome, a composite endpoint that involves dichotomising a continuous measure. An augmented binary method that improves power whilst retaining the original responder endpoint has previously been proposed. The method leverages information from the the undichotomised component to improve power. We extend this method for basket trials, which are gaining popularity in many clinical areas. For clinical…

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Causal Inference on Process Graphs, Part I: The Structural Equation Process Representation

过程图上的因果推断(一):结构方程过程表示

When dealing with time series data, causal inference methods often employ structural vector autoregressive (SVAR) processes to model time-evolving random systems. In this work, we rephrase recursive SVAR processes with possible latent component processes as a linear Structural Causal Model (SCM) of stochastic processes on a simple causal graph, the process graph, that models every process as a single node. Using this reformulation, we generalise Wright's well-known path-rule…

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Causal Inference on Process Graphs, Part II: Causal Structure and Effect Identification

过程图上的因果推断(二):因果结构与效应识别

A structural vector autoregressive (SVAR) process is a linear causal model for variables that evolve over a discrete set of time points and between which there may be lagged and instantaneous effects. The qualitative causal structure of an SVAR process can be represented by its finite and directed process graph, in which a directed link connects two processes whenever there is a lagged or instantaneous effect between them. At the process graph level, the causal structure of…

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Estimating Causal Effects for Binary Outcomes Using Per-Decision Inverse Probability Weighting

用逐决策逆概率加权估计二元结局因果效应

Micro-randomized trials are commonly conducted for optimizing mobile health interventions such as push notifications for behavior change. In analyzing such trials, causal excursion effects are often of primary interest, and their estimation typically involves inverse probability weighting (IPW). However, in a micro-randomized trial, additional treatments can often occur during the time window over which an outcome is defined, and this can greatly inflate the variance of the…

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Anytime-valid off-policy inference for contextual bandits

情境赌博机的任意时刻有效离策略推断

Contextual bandit algorithms are ubiquitous tools for active sequential experimentation in healthcare and the tech industry. They involve online learning algorithms that adaptively learn policies over time to map observed contexts $X_t$ to actions $A_t$ in an attempt to maximize stochastic rewards $R_t$. This adaptivity raises interesting but hard statistical inference questions, especially counterfactual ones: for example, it is often of interest to estimate the properties…

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Classification of High-dimensional Time Series in Spectral Domain using Explainable Features

利用可解释频域特征分类高维时间序列

Interpretable classification of time series presents significant challenges in high dimensions. Traditional feature selection methods in the frequency domain often assume sparsity in spectral density matrices (SDMs) or their inverses, which can be restrictive for real-world applications. In this article, we propose a model-based approach for classifying high-dimensional stationary time series by assuming sparsity in the difference between inverse SDMs. Our approach…

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Probabilistic Quantile Factor Analysis

概率分位数因子分析

This paper extends quantile factor analysis to a probabilistic variant that incorporates regularization and computationally efficient variational approximations. We establish through synthetic and real data experiments that the proposed estimator can, in many cases, achieve better accuracy than a recently proposed loss-based estimator. We contribute to the factor analysis literature by extracting new indexes of \emph{low}, \emph{medium}, and \emph{high} economic policy…

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On the effect of noise on fitting linear regression models

噪声对线性回归模型拟合的影响

In this study, we explore the effects of including noise predictors and noise observations when fitting linear regression models. We present empirical and theoretical results that show that double descent occurs in both cases, albeit with contradictory implications: the implication for noise predictors is that complex models are often better than simple ones, while the implication for noise observations is that simple models are often better than complex ones. We resolve…

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Inverting estimating equations for causal inference on quantiles

通过反演估计方程进行分位数因果推断

The causal inference literature frequently focuses on estimating the mean of the potential outcome, whereas quantiles of the potential outcome may carry important additional information. We propose a unified approach, based on the inverse estimating equations, to generalize a class of causal inference solutions from estimating the mean of the potential outcome to its quantiles. We assume that a moment function is available to identify the mean of the threshold-transformed…

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Your MMM is Broken: Identification of Nonlinear and Time-varying Effects in Marketing Mix Models

营销组合模型的识别困境:非线性与时变效应

Recent years have seen a resurgence in interest in marketing mix models (MMMs), which are aggregate-level models of marketing effectiveness. Often these models incorporate nonlinear effects, and either implicitly or explicitly assume that marketing effectiveness varies over time. In this paper, we show that nonlinear and time-varying effects are often not identifiable from standard marketing mix data: while certain data patterns may be suggestive of nonlinear effects, such…

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A General Framework for Treatment Effect Estimation in Semi-Supervised and High Dimensional Settings

半监督与高维环境下处理效应估计的一般框架

In this article, we aim to provide a general and complete understanding of semi-supervised (SS) causal inference for treatment effects. Specifically, we consider two such estimands: (a) the average treatment effect and (b) the quantile treatment effect, as prototype cases, in an SS setting, characterized by two available data sets: (i) a labeled data set of size $n$, providing observations for a response and a set of high dimensional covariates, as well as a binary treatment…

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Estimation of the Number Needed to Treat, the Number Needed to be Exposed, and the Exposure Impact Number with Instrumental Variables

使用工具变量估计需治疗人数、需暴露人数与暴露影响人数

The Number needed to treat (NNT) is an efficacy index defined as the average number of patients needed to treat to attain one additional treatment benefit. In observational studies, specifically in epidemiology, the adequacy of the populationwise NNT is questionable since the exposed group characteristics may substantially differ from the unexposed. To address this issue, groupwise efficacy indices were defined: the Exposure Impact Number (EIN) for the exposed group and the…

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Causal Effect Estimation using identifiable Variational AutoEncoder with Latent Confounders and Post-Treatment Variables

利用可识别变分自编码器处理潜在混杂与处理后变量的因果效应估计

Estimating causal effects from observational data is challenging, especially in the presence of latent confounders. Much work has been done on addressing this challenge, but most of the existing research ignores the bias introduced by the post-treatment variables. In this paper, we propose a novel method of joint Variational AutoEncoder (VAE) and identifiable Variational AutoEncoder (iVAE) for learning the representations of latent confounders and latent post-treatment…

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Inference for Local Projections

局部投影的推断

Inference for impulse responses estimated with local projections presents interesting challenges and opportunities. Analysts typically want to assess the precision of individual estimates, explore the dynamic evolution of the response over particular regions, and generally determine whether the impulse generates a response that is any different from the null of no effect. Each of these goals requires a different approach to inference. In this article, we provide an overview…

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A Sparse Grid Approach for the Nonparametric Estimation of High-Dimensional Random Coefficient Models

高维随机系数模型非参数估计的稀疏网格方法

A severe limitation of many nonparametric estimators for random coefficient models is the exponential increase of the number of parameters in the number of random coefficients included into the model. This property, known as the curse of dimensionality, restricts the application of such estimators to models with moderately few random coefficients. This paper proposes a scalable nonparametric estimator for high-dimensional random coefficient models. The estimator uses a…

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Quadratic functional estimation from observations with multiplicative measurement error

乘性测量误差下二次泛函的非参数估计

We consider the nonparametric estimation of the value of a quadratic functional evaluated at the density of a strictly positive random variable $X$ based on an iid. sample from an observation $Y$ of $X$ corrupted by an independent multiplicative error $U$. Quadratic functionals of the density covered are the $\mathbb{L}^2$-norm of the density and its derivatives or the survival function. We construct a fully data-driven estimator when the error density is known. The plug-in…

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