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Eliciting prior information from clinical trials via calibrated Bayes factor

通过校准贝叶斯因子提取临床试验的先验信息

In the Bayesian framework power prior distributions are increasingly adopted in clinical trials and similar studies to incorporate external and past information, typically to inform the parameter associated to a treatment effect. Their use is particularly effective in scenarios with small sample sizes and where robust prior information is actually available. A crucial component of this methodology is represented by its weight parameter, which controls the volume of…

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The typicality principle and its implications for statistics and data science

典型性原则及其对统计学与数据科学的启示

A central focus of data science is the transformation of empirical evidence into knowledge. As such, the key insights and scientific attitudes of deep thinkers like Fisher, Popper, and Tukey are expected to inspire exciting new advances in machine learning and artificial intelligence in years to come. Along these lines, the present paper advances a novel {\em typicality principle} which states, roughly, that if the observed data is sufficiently ``atypical'' in a certain…

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Quantitative Theory of Money or Prices? A Historical, Theoretical, and Econometric Analysis

货币数量论还是价格数量论?历史、理论与计量分析

This research studies the relation between money and prices and its practical implications analyzing quarterly data from United States (1959-2022), Canada (1961-2022), United Kingdom (1986-2022), and Brazil (1996-2022). The historical, logical, and econometric consistency of the logical core of the two main theories of money is analyzed using objective bayesian and frequentist machine learning models, bayesian regularized artificial neural networks, and ensemble learning. It…

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Minimax Optimal Design with Spillover and Carryover Effects

兼顾溢出与延续效应的极小极大最优实验设计

In various applications, the potential outcome of a unit may be influenced by the treatments received by other units, a phenomenon known as interference, as well as by prior treatments, referred to as carryover effects. These phenomena violate the stable unit treatment value assumption and pose significant challenges in causal inference. To address these complexities, we propose a minimax optimal experimental design that simultaneously accounts for both spillover and…

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Triple Instrumented Difference-in-Differences

三重差分工具变量设计

In this paper, we formalize a triple instrumented difference-in-differences (DID-IV). In this design, a triple Wald-DID estimand, which divides the difference-in-difference-in-differences (DDD) estimand of the outcome by the DDD estimand of the treatment, captures the local average treatment effect on the treated. The identifying assumptions mainly comprise a monotonicity assumption, and the common acceleration assumptions in the treatment and the outcome. We extend the…

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Detecting Cointegrating Relations in Non-stationary Matrix-Valued Time Series

非平稳矩阵值时间序列的协整关系检测

This paper proposes a Matrix Error Correction Model to identify cointegration relations in matrix-valued time series. We hereby allow separate cointegrating relations along the rows and columns of the matrix-valued time series and use information criteria to select the cointegration ranks. Through Monte Carlo simulations and a macroeconomic application, we demonstrate that our approach provides a reliable estimation of the number of cointegrating relationships.

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A Semiparametric Bayesian Method for Instrumental Variable Analysis with Partly Interval-Censored Time-to-Event Outcome

部分区间删失事件时间结局的半参数贝叶斯工具变量分析

This paper develops a semiparametric Bayesian instrumental variable analysis method for estimating the causal effect of an endogenous variable when dealing with unobserved confounders and measurement errors with partly interval-censored time-to-event data, where event times are observed exactly for some subjects but left-censored, right-censored, or interval-censored for others. Our method is based on a two-stage Dirichlet process mixture instrumental variable (DPMIV) model…

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Isotonic propensity score matching

保序倾向得分匹配

We propose a one-to-many matching estimator of the average treatment effect based on propensity scores estimated by isotonic regression. This approach is predicated on the assumption of monotonicity in the propensity score function, a condition that can be justified in many economic applications. We show that the nature of the isotonic estimator can help us to fix many problems of existing matching methods, including efficiency, choice of the number of matches, choice of…

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Using negative controls to identify causal effects with invalid instrumental variables

利用负对照识别无效工具变量下的因果效应

Many proposals for the identification of causal effects require an instrumental variable that satisfies strong, untestable unconfoundedness and exclusion restriction assumptions. In this paper, we show how one can potentially identify causal effects under violations of these assumptions by harnessing a negative control population or outcome. This strategy allows one to leverage sub-populations for whom the exposure is degenerate, and requires that the instrument-outcome…

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High-Dimensional Canonical Correlation Analysis

高维典型相关分析

This paper studies high-dimensional canonical correlation analysis (CCA) with an emphasis on the vectors that define canonical variables. The paper shows that when two dimensions of data grow to infinity jointly and proportionally, the classical CCA procedure for estimating those vectors fails to deliver a consistent estimate. This provides the first result on the impossibility of identification of canonical variables in the CCA procedure when all dimensions are large. As a…

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Signal-to-noise ratio aware minimax analysis of sparse linear regression

稀疏线性回归的信噪比感知极小极大分析

We consider parameter estimation under sparse linear regression -- an extensively studied problem in high-dimensional statistics and compressed sensing. While the minimax framework has been one of the most fundamental approaches for studying statistical optimality in this problem, we identify two important issues that the existing minimax analyses face: (i) The signal-to-noise ratio appears to have no effect on the minimax optimality, while it shows a major impact in…

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Robust Bayesian graphical modeling using $γ$-divergence

基于γ散度的稳健贝叶斯图模型

Gaussian graphical model is one of the powerful tools to analyze conditional independence between two variables for multivariate Gaussian-distributed observations. When the dimension of data is moderate or high, penalized likelihood methods such as the graphical lasso are useful to detect significant conditional independence structures. However, the estimates are affected by outliers due to the Gaussian assumption. This paper proposes a novel robust posterior distribution…

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An Adaptive Moving Average for Macroeconomic Monitoring

用于宏观经济监测的自适应移动平均

The use of moving averages is pervasive in macroeconomic monitoring, particularly for tracking noisy series such as inflation. The choice of the look-back window is crucial. Too long of a moving average is not timely enough when faced with rapidly evolving economic conditions. Too narrow averages are noisy, limiting signal extraction capabilities. As is well known, this is a bias-variance trade-off. However, it is a time-varying one: the optimal size of the look-back window…

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The Dynamic Triple Gamma Prior as a Shrinkage Process Prior for Time-Varying Parameter Models

时变参数模型的动态三重伽马收缩过程先验

Many existing shrinkage approaches for time-varying parameter (TVP) models assume constant innovation variances across time points, inducing sparsity by shrinking these variances toward zero. However, this assumption falls short when states exhibit large jumps or structural changes, as often seen in empirical time series analysis. To address this, we propose the dynamic triple gamma prior -- a stochastic process that induces time-dependent shrinkage by modeling dependence…

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Causality for VARMA processes with instantaneous effects: The global Markov property, faithfulness and instrumental variables

含即时效应的 VARMA 过程:全局马尔可夫性、忠实性与工具变量

Causal reasoning has gained great attention over the last half century as it allows (or at least intends) to answer questions which go above those within the capabilities of classical inferential statistics using just observational data. So far, causal research has been focused mostly on the i.i.d. setting. However, many are the situations where there exists a non-trivial dependence structure between sequential observations. Motivated by this fact, the main purpose of this…

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Sparse factor models of high dimension

高维稀疏因子模型

We consider the estimation of a sparse factor model where the factor loading matrix is assumed sparse. The estimation problem is reformulated as a penalized M-estimation criterion, while the restrictions for identifying the factor loading matrix accommodate a wide range of sparsity patterns. We prove the sparsistency property of the penalized estimator when the number of parameters is diverging, that is the consistency of the estimator and the recovery of the true zeros…

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Differentiable Causal Discovery of Linear Non-Gaussian Acyclic Models Under Unmeasured Confounding

未观测混杂下线性非高斯无环模型的可微因果发现

We propose a novel score-based causal discovery method, named ABIC LiNGAM, which extends the linear non-Gaussian acyclic model (LiNGAM) framework to address the challenges of causal structure estimation in scenarios involving unmeasured confounders. By introducing the assumption that error terms follow a multivariate generalized normal distribution, our method leverages continuous optimization techniques to recover acyclic directed mixed graphs (ADMGs), including causal…

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Testing and Estimating Structural Breaks in Time Series and Panel Data in Stata

在 Stata 中检验和估计时间序列与面板数据的结构突变

Identifying structural change is a crucial step in analysis of time series and panel data. The longer the time span, the higher the likelihood that the model parameters have changed as a result of major disruptive events, such as the 2007--2008 financial crisis and the 2020 COVID--19 outbreak. Detecting the existence of breaks, and dating them is therefore necessary, not only for estimation purposes but also for understanding drivers of change and their effect on…

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Sparsity meets correlation in Gaussian sequence model

高斯序列模型中的稀疏性与相关性

We study estimation of an $s$-sparse signal in the $p$-dimensional Gaussian sequence model with equicorrelated observations and derive the minimax rate. A new phenomenon emerges from correlation, namely the rate scales with respect to $p-2s$ and exhibits a phase transition at $p-2s \asymp \sqrt{p}$. Correlation is shown to be a blessing provided it is sufficiently strong, and the critical correlation level exhibits a delicate dependence on the sparsity level. Due to…

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On the Role of Surrogates in Conformal Inference of Individual Causal Effects

替代指标在个体因果效应共形推断中的作用

Learning the Individual Treatment Effect (ITE) is essential for personalized decision-making, yet causal inference has traditionally focused on aggregated treatment effects. While integrating conformal prediction with causal inference can provide valid uncertainty quantification for ITEs, the resulting prediction intervals are often excessively wide, limiting their practical utility. To address this limitation, we introduce \underline{S}urrogate-assisted…

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Minimax Optimal Simple Regret in Two-Armed Best-Arm Identification

双臂最优臂识别中简单遗憾的极小极大最优性

This study investigates an asymptotically minimax optimal algorithm in the two-armed fixed-budget best-arm identification (BAI) problem. Given two treatment arms, the objective is to identify the arm with the highest expected outcome through an adaptive experiment. We focus on the Neyman allocation, where treatment arms are allocated following the ratio of their outcome standard deviations. Our primary contribution is to prove the minimax optimality of the Neyman allocation…

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Outcome-Assisted Multiple Imputation of Missing Treatments

利用结果信息辅助缺失处理状态的多重插补

We provide guidance on multiple imputation of missing at random treatments in observational studies. Specifically, analysts should account for both covariates and outcomes, i.e., not just use propensity scores, when imputing the missing treatments. To do so, we develop outcome-assisted multiple imputation of missing treatments: the analyst fits a regression for the outcome on the treatment indicator and covariates, which is used to sharpen the predictive probabilities for…

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Difference-in-Differences with Multiple Events

存在多个事件的双重差分

This paper studies staggered Difference-in-Differences (DiD) design when there is a second event confounding the target event. When the events are correlated, the treatment and the control group are unevenly exposed to the effects of the second event, causing an omitted event bias. To address this bias, I propose a two-stage DiD design. In the first stage, I estimate the combined effects of both treatments using a control group that is neither treated nor confounded. In the…

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Two-way Matrix Autoregressive Model with Thresholds

具有双向门限的矩阵自回归模型

Recently, matrix-valued time series data have attracted significant attention in the literature with the recognition of threshold nonlinearity representing a significant advance. However, given the fact that a matrix is a two-array structure, it is unfortunate, perhaps even unusual, for the threshold literature to focus on using the same threshold variable for the rows and the columns. In fact, evidence in economic, financial, environmental and other data shows advantages of…

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