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Uniform confidence bands for joint angles across different fatigue phases

不同疲劳阶段关节角度的统一置信带

We develop uniform confidence bands for the mean function of stationary time series as a post-hoc analysis of multiple change point detection in functional time series. In particular, the methodology in this work provides bands for those segments where the jump size exceeds a certain threshold $Δ$. In \cite{bastian2024multiplechangepointdetection} such exceedences of $Δ$ were related to fatigue states of a running athlete. The extension to confidence bands stems from an…

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Inference in dynamic models for panel data using the moving block bootstrap

动态面板模型中的移动块自助法推断

Inference in linear panel data models is complicated by the presence of fixed effects when (some of) the regressors are not strictly exogenous. Under asymptotics where the number of cross-sectional observations and time periods grow at the same rate, the within-group estimator is consistent but its limit distribution features a bias term. In this paper we show that a panel version of the moving block bootstrap, where blocks of adjacent cross-sections are resampled with…

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Trend estimation for time series with polynomial-tailed noise

多项式尾部噪声下的时间序列趋势估计

For time series data observed at non-random and possibly non-equidistant time points, we estimate the trend function nonparametrically. Under the assumption of a bounded total variation of the function and low-order moment conditions on the errors we propose a nonlinear wavelet estimator which uses a Haar-type basis adapted to a possibly non-dyadic sample size. An appropriate thresholding scheme for sparse signals with an additive polynomial-tailed noise is first derived in…

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Score-Based Causal Discovery with Temporal Background Information

利用时间背景信息的评分式因果发现

Temporal background information can improve causal discovery algorithms by orienting edges and identifying relevant adjustment sets. We develop the Temporal Greedy Equivalence Search (TGES) algorithm and terminology essential for score-based causal discovery with tiered background knowledge. TGES learns a restricted Markov equivalence class of directed acyclic graphs (DAGs) using observational data and tiered background knowledge. To construct TGES we formulate a scoring…

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Robust Estimation and Inference for High-Dimensional Panel Data Models

高维面板数据模型的稳健估计与推断

This paper provides the relevant literature with a complete toolkit for conducting robust estimation and inference about the parameters of interest involved in a high-dimensional panel data framework. Specifically, (1) we allow for non-Gaussian, serially and cross-sectionally correlated and heteroskedastic error processes, (2) we develop an estimation method for high-dimensional long-run covariance matrix using a thresholded estimator, (3) we also allow for the number of…

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Knowledge-Guided Wasserstein Distributionally Robust Optimization

知识引导的 Wasserstein 分布稳健优化

Transfer learning is a popular strategy to leverage external knowledge and improve statistical efficiency, particularly with a limited target sample. We propose a novel knowledge-guided Wasserstein Distributionally Robust Optimization (KG-WDRO) framework that adaptively incorporates multiple sources of external knowledge to overcome the conservativeness of vanilla WDRO, which often results in overly pessimistic shrinkage toward zero. Our method constructs smaller Wasserstein…

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Bias Mitigation in Matched Observational Studies with Continuous Treatments: Calipered Non-Bipartite Matching and Bias-Corrected Estimation and Inference

连续处理匹配观察研究的偏差缓解:卡尺非二分匹配与偏差修正推断

In matched observational studies with continuous treatments, individuals with different treatment doses but the same or similar covariate values are paired for causal inference. While inexact covariate matching (i.e., covariate imbalance after matching) is common in practice, previous matched studies with continuous treatments have often overlooked this issue as long as post-matching covariate balance meets certain criteria. Through re-analyzing a matched observational study…

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Variational Causal Inference

变分因果推断

Estimating an individual's potential outcomes under counterfactual treatments is a challenging task for traditional causal inference and supervised learning approaches when the outcome is high-dimensional (e.g. gene expressions, impulse responses, human faces) and covariates are relatively limited. In this case, to construct one's outcome under a counterfactual treatment, it is crucial to leverage individual information contained in its observed factual outcome on top of the…

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Predicting Cellular Responses with Variational Causal Inference and Refined Relational Information

结合变分因果推断与细化关系信息预测细胞响应

Predicting the responses of a cell under perturbations may bring important benefits to drug discovery and personalized therapeutics. In this work, we propose a novel graph variational Bayesian causal inference framework to predict a cell's gene expressions under counterfactual perturbations (perturbations that this cell did not factually receive), leveraging information representing biological knowledge in the form of gene regulatory networks (GRNs) to aid individualized…

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Using Multiple Outcomes to Improve the Synthetic Control Method

利用多个结果变量改进合成控制方法

When there are multiple outcome series of interest, Synthetic Control analyses typically proceed by estimating separate weights for each outcome. In this paper, we instead propose estimating a common set of weights across outcomes, by balancing either a vector of all outcomes or an index or average of them. Under a low-rank factor model, we show that these approaches lead to lower bias bounds than separate weights, and that averaging leads to further gains when the number of…

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Bad estimation, good prediction: the Lasso in dense regimes

糟糕的估计,良好的预测:稠密情形下的 Lasso

For high-dimensional omics data, sparsity-inducing regularization methods such as the Lasso are widely used and often yield strong predictive performance, even in settings when the assumption of sparsity is likely violated. We demonstrate that under a specific dense model, namely the high-dimensional joint latent variable model, the Lasso produces sparse prediction rules with favorable prediction error bounds, even when the underlying regression coefficient vector is not…

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Model-free Methods for Event History Analysis and Efficient Adjustment (PhD Thesis)

事件史分析与高效调整的无模型方法:博士论文

This thesis contains a series of independent contributions to statistics, unified by a model-free perspective. The first chapter elaborates on how a model-free perspective can be used to formulate flexible methods that leverage prediction techniques from machine learning. Mathematical insights are obtained from concrete examples, and these insights are generalized to principles that permeate the rest of the thesis. The second chapter studies the concept of local…

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Harmonized Estimation of Subgroup-Specific Treatment Effects in Randomized Trials: The Use of External Control Data

随机试验亚组处理效应的协调估计:外部对照数据的使用

Subgroup analyses of randomized controlled trials (RCTs) constitute an important component of the drug development process in precision medicine. In particular, subgroup analyses of early-stage trials often influence the design and eligibility criteria of subsequent confirmatory trials and ultimately influence which subpopulations will receive the treatment after regulatory approval. However, subgroup analyses are often complicated by small sample sizes, which leads to…

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Isotonic Mechanism for Exponential Family Estimation in Machine Learning Peer Review

机器学习同行评审中用于指数族估计的保序机制

In 2023, the International Conference on Machine Learning (ICML) required authors with multiple submissions to rank their submissions based on perceived quality. In this paper, we aim to employ these author-specified rankings to enhance peer review in machine learning and artificial intelligence conferences by extending the Isotonic Mechanism to exponential family distributions. This mechanism generates adjusted scores that closely align with the original scores while…

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The Variable Multiple Bandpass Periodic Block Bootstrap for Time Series with Multiple Periodic Correlations

多重周期相关时间序列的可变多重带通周期分块自助法

This work introduces a novel block bootstrap method for time series with multiple periodically correlated (MPC) components called the Variable Multiple Bandpass Periodic Block Bootstrap (VMBPBB). While past methodological advancements permitted bootstrapping time series to preserve certain correlations, and then periodically correlated (PC) structures, there does not appear to be adequate or efficient methods to bootstrap estimate the sampling distribution of estimators for…

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Uniform Kernel Prober

均匀核探测子

The ability to identify useful features or representations of the input data based on training data that achieves low prediction error on test data across multiple prediction tasks is considered the key to multitask learning success. In practice, however, one faces the issue of the choice of prediction tasks and the availability of test data from the chosen tasks while comparing the relative performance of different features. In this work, we develop a class of pseudometrics…

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Missing Data in Discrete Time State-Space Modeling of Ecological Momentary Assessment Data: A Monte-Carlo Study of Imputation Methods

生态瞬时评估数据离散时间状态空间建模中的缺失数据:插补方法蒙特卡洛研究

When using ecological momentary assessment data (EMA), missing data is pervasive as participant attrition is a common issue. Thus, any EMA study must have a missing data plan. In this paper, we discuss missingness in time series analysis and the appropriate way to handle missing data when the data is modeled as an idiographic discrete time continuous measure state-space model. We found that Missing Completely At Random, Missing At Random, and Time-dependent Missing At Random…

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Cover It Up! Bipartite Graphs Uncover Identifiability in Sparse Factor Analysis

用二部图揭示稀疏因子分析的可识别性

Despite the popularity of factor models with sparse loading matrices, little attention has been given to formally address identifiability of these models beyond standard rotation-based identification such as the positive lower triangular constraint. To fill this gap, we present a counting rule on the number of nonzero factor loadings that is sufficient for achieving generic uniqueness of the variance decomposition in the factor representation. This is formalized in the…

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Power and sample size calculation for multivariate longitudinal trials using the longitudinal rank sum test

基于纵向秩和检验的多变量纵向试验功效与样本量计算

Neurodegenerative diseases such as Alzheimer's and Parkinson's often exhibit complex, multivariate longitudinal outcomes that require advanced statistical methods to comprehensively evaluate treatment efficacy. The Longitudinal Rank Sum Test (LRST) offers a nonparametric framework to assess global treatment effects across multiple longitudinal endpoints without requiring multiplicity corrections. This study develops a robust methodology for power and sample size estimation…

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Augmented two-stage estimation for treatment crossover in oncology trials: Leveraging external data for improved precision

肿瘤试验处理交叉的增强两阶段估计:利用外部数据提高精度

Randomized controlled trials (RCTs) in oncology often allow control group participants to crossover to experimental treatments, a practice that, while often ethically necessary, complicates the accurate estimation of long-term treatment effects. When crossover rates are high or sample sizes are limited, commonly used methods for crossover adjustment (such as the rank-preserving structural failure time model, inverse probability of censoring weights, and two-stage estimation…

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Shapley-PC: Constraint-based Causal Structure Learning with a Shapley Inspired Framework

Shapley-PC:受 Shapley 值启发的约束型因果结构学习

Causal Structure Learning (CSL), also referred to as causal discovery, amounts to extracting causal relations among variables in data. CSL enables the estimation of causal effects from observational data alone, avoiding the need to perform real life experiments. Constraint-based CSL leverages conditional independence tests to perform causal discovery. We propose Shapley-PC, a novel method to improve constraint-based CSL algorithms by using Shapley values over the possible…

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Analysis of Two-Stage Rollout Designs with Clustering for Causal Inference under Network Interference

网络干扰下带聚类的两阶段逐步投放实验设计分析

Estimating causal effects under interference is pertinent to many real-world settings. Recent work with low-order potential outcomes models uses a rollout design to obtain unbiased estimators that require no interference network information. However, the required extrapolation can lead to prohibitively high variance. To address this, we propose a two-stage experiment that selects a sub-population in the first stage and restricts treatment rollout to this sub-population in…

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Comment on "Generic machine learning inference on heterogeneous treatment effects in randomized experiments."

评《随机实验中异质处理效应的通用机器学习推断》

We analyze the split-sample robust inference (SSRI) methodology proposed by Chernozhukov, Demirer, Duflo, and Fernandez-Val (CDDF) for quantifying uncertainty in heterogeneous treatment effect estimation. While SSRI effectively accounts for randomness in data splitting, its computational cost can be prohibitive when combined with complex machine learning (ML) models. We present an alternative randomization inference (RI) approach that maintains SSRI's generality without…

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Covariates-Adjusted Mixed-Membership Estimation: A Novel Network Model with Optimal Guarantees

协变量调整的混合成员估计:网络模型与最优保证

This paper addresses the problem of mixed-membership estimation in networks, where the goal is to efficiently estimate the latent mixed-membership structure from the observed network. Recognizing the widespread availability and valuable information carried by node covariates, we propose a novel network model that incorporates both community information, as represented by the Degree-Corrected Mixed Membership (DCMM) model, and node covariate similarities to determine…

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