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When Is Causal Inference Possible? A Statistical Test for Unmeasured Confounding

何时可以进行因果推断?未测量混杂的统计检验

This paper clarifies a fundamental difference between causal inference and traditional statistical inference by formalizing a mathematical distinction between their respective parameters. We connect two major approaches to causal inference, the potential outcomes framework and causal structure graphs, which are typically studied separately. While the unconfoundedness assumption in the potential outcomes framework cannot be assessed from an observational dataset alone, causal…

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HAL-Based Plug-in Estimation with Pointwise Asymptotic Normality of the Causal Dose-Response Curve

基于 HAL 的因果剂量反应曲线插件估计与逐点渐近正态性

Estimating and obtaining reliable inference for the marginally adjusted causal dose-response curve for continuous treatments without relying on parametric assumptions is a well-known statistical challenge. Parametric models risk introducing significant bias through model misspecification, compromising the accurate representation of the underlying data and dose-response relationship. On the other hand, nonparametric models face difficulties as the dose-response curve is not…

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Bounds in Wasserstein Distance for Locally Stationary Processes

局部平稳过程的 Wasserstein 距离界

Locally stationary (LSPs) constitute an essential modeling paradigm for capturing the nuanced dynamics inherent in time series data whose statistical characteristics, including mean and variance, evolve smoothly across time. In this paper, we introduce a novel conditional probability distribution estimator specifically tailored for LSPs, employing the Nadaraya-Watson (NW) kernel smoothing methodology. The NW estimator, a prominent local averaging technique, leverages kernel…

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Inference on Partially Identified Parameters with Separable Nuisance Parameters: a Two-Stage Method

可分离辅助参数下部分识别参数的两阶段推断

This paper develops a two-stage method for inference on partially identified parameters in moment inequality models with separable nuisance parameters. In the first stage, the nuisance parameters are estimated separately, and in the second stage, the identified set for the parameters of interest is constructed using a refined chi-squared test with variance correction that accounts for the first-stage estimation error. We establish the asymptotic validity of the proposed…

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A mixture logistic model for panel data with a Markov structure

具有马尔可夫结构的面板数据混合逻辑回归模型

In this study, we propose a mixture logistic regression model with a Markov structure, and consider the estimation of model parameters using maximum likelihood estimation. We also provide a forward type variable selection algorithm to choose the important explanatory variables to reduce the number of parameters in the proposed model.

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Network Modeling of Asynchronous Change-Points in Multivariate Time Series

多变量时间序列中异步变点的网络建模

This article introduces a novel Bayesian method for asynchronous change-point detection in multivariate time series. This method allows for change-points to occur earlier in some (leading) series followed, after a short delay, by change-points in some other (lagging) series. Such dynamic dependence structure is common in fields such as seismology and neurology where a latent event such as an earthquake or seizure causes certain sensors to register change-points before…

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The Bayesian Context Trees State Space Model for time series modelling and forecasting

用于时间序列建模与预测的贝叶斯上下文树状态空间模型

A hierarchical Bayesian framework is introduced for developing tree-based mixture models for time series, partly motivated by applications in finance and forecasting. At the top level, meaningful discrete states are identified as appropriately quantised values of some of the most recent samples. At the bottom level, a different, arbitrary base model is associated with each state. This defines a very general framework that can be used in conjunction with any existing model…

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Inspection-Guided Randomization: A Flexible and Transparent Restricted Randomization Framework for Better Experimental Design

检查引导随机化:灵活透明的受限随机化实验设计框架

Randomized experiments are considered the gold standard for estimating causal effects. However, out of the set of possible randomized assignments, some may be likely to produce poor effect estimates and misleading conclusions. Restricted randomization is an experimental design strategy that filters out undesirable treatment assignments, but its application has primarily been limited to ensuring covariate balance in two-arm studies where the target estimand is the average…

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Network inference via approximate Bayesian computation. Illustration on a stochastic multi-population neural mass model

近似贝叶斯计算的网络推断:随机多群体神经质量模型示例

In this article, we propose an adapted sequential Monte Carlo approximate Bayesian computation (SMC-ABC) algorithm for network inference in coupled stochastic differential equations (SDEs) used for multivariate time series modeling. Our approach is motivated by neuroscience, specifically the challenge of estimating brain connectivity before and during epileptic seizures. To this end, we make four key contributions. First, we introduce a 6N-dimensional SDE to model the…

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Estimating the average treatment effect in cluster-randomized trials with misclassified outcomes and non-random validation subsets

结局误分类与非随机验证子集下整群随机试验的平均处理效应估计

Randomized trials are viewed as the benchmark for assessing causal effects of treatments on outcomes of interest. Nonetheless, challenges such as measurement error can undermine the standard causal assumptions for randomized trials. In ASPIRE, a cluster-randomized trial, pediatric primary care clinics were assigned to one of two treatments aimed at promoting clinician delivery of a secure firearm program to parents during well-child visits. A key outcome of interest is thus…

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Sparse minimum Redundancy Maximum Relevance for feature selection

稀疏最小冗余最大相关特征选择方法

We propose a feature screening method that integrates both feature-feature and feature-target relationships. Inactive features are identified via a penalized minimum Redundancy Maximum Relevance (mRMR) procedure, which is the continuous version of the classic mRMR penalized by a non-convex regularizer, and where the parameters estimated as zero coefficients represent the set of inactive features. We establish the conditions under which zero coefficients are correctly…

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Adaptive estimation for nonparametric circular regression with errors in variables

含变量误差的非参数圆形回归自适应估计

This paper investigates the nonparametric estimation of a circular regression function in an errors-in-variables framework. Two settings are studied, depending on whether the covariates are circular or linear. Adaptive estimators are constructed and their theoretical performance is assessed through convergence rates over Sobolev and Hölder smoothness classes. Numerical experiments on simulated and real datasets illustrate the practical relevance of the methodology.

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Matching-Based Nonparametric Estimation of Group Average Treatment Effects

基于匹配的组平均处理效应非参数估计

Heterogeneous treatment effects, which vary according to individual covariates, are crucial in fields such as personalized medicine and tailored treatment strategies. In many applications, rather than considering the heterogeneity induced by all covariates, practitioners focus on a few key covariates to develop tailored treatment decisions. Based on this, we aim to estimate the group average treatment effects (GATEs), which represent heterogeneous treatment effects across…

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Nonlinear Impulse Response Functions and Local Projections

非线性脉冲响应函数与局部投影

The goal of this paper is to extend the nonparametric estimation of Impulse Response Functions (IRF) by means of local projections in the nonlinear dynamic framework. We discuss the existence of a nonlinear autoregressive representation for Markov processes and explain how their IRFs are directly linked to the Nonlinear Local Projection (NLP), as in the case for the linear setting. We present a fully nonparametric LP estimator in the one dimensional nonlinear framework,…

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Causal Inference in Longitudinal Data under Unknown Interference

未知干扰结构下纵向数据的因果推断

In longitudinal studies where units are embedded in space or a social network, interference may arise, meaning that a unit's outcome can depend on treatment histories of others. The presence of interference poses significant challenges for causal inference, particularly when the interference structure -- how a unit's outcome responds to others' influences -- is complex, heterogeneous, and unknown to researchers. This paper develops a general framework for identifying and…

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Utilizing Multiple Testing for Grouping in Singular Spectrum Analysis

利用多重检验进行奇异谱分析分组

A key step in separating signal from noise in time series by means of singular spectrum analysis (SSA) is grouping. We present a multiple testing method for the grouping step in SSA. As separability criterion, we utilize the weighted correlation between the signal and the noise component of the (reconstructed) time series, and we test whether this weighted correlation is equal to zero. This test has to be performed for several possible groupings, resulting in a multiple test…

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Tensor-product interactions in Markov-switching models

马尔可夫转换模型中的张量积交互

Markov-switching models are a powerful tool for modelling time series data that are driven by underlying latent states. As such, they are widely used in behavioural ecology, where discrete states can serve as proxies for behavioural modes and enable inference on latent behaviour driving e.g. observed movement. To understand drivers of behavioural changes, it is common to link model parameters to covariates. Over the last decade, nonparametric approaches have gained traction…

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Testing Simultaneous Diagonalizability

同时可对角化的统计检验

This paper proposes novel methods to test for simultaneous diagonalization of possibly asymmetric matrices. Motivated by various applications, a two-sample test as well as a generalization for multiple matrices are proposed. A partial version of the test is also studied to check whether a partial set of eigenvectors is shared across samples. Additionally, a novel algorithm for the considered testing methods is introduced. Simulation studies demonstrate favorable performance…

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Tracking Temporal Evolution of Topological Features in Image Data

追踪图像数据中拓扑特征的时间演化

Topological Data Analysis (TDA) can be used to detect and characterize holes in an image, such as zero-dimensional holes (connected components) or one-dimensional holes (loops). However, there is currently no widely accepted statistical framework for modeling spatiotemporal dependence in the evolution of topological features, such as holes, within a time series of images. We propose a hypothesis testing framework to identify statistically significant topological features of…

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Causal Effect Identification and Inference with Endogenous Exposures and a Light-tailed Error

内生暴露与轻尾误差下的因果效应识别和推断

Endogeneity poses significant challenges in causal inference across various research domains. This paper proposes a novel approach to identify and estimate causal effects in the presence of endogeneity. We consider a structural equation with endogenous exposures and an additive error term. Assuming the light-tailedness of the error term, we show that the causal effect can be identified by contrasting extreme conditional quantiles of the outcome given the exposures. Unlike…

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Source-Condition Analysis of Kernel Adversarial Estimators

核对抗估计量的源条件分析

In many applications, the target parameter depends on a nuisance function defined by a conditional moment restriction, whose estimation often leads to an ill-posed inverse problem. Classical approaches, such as sieve-based GMM, approximate the restriction using a fixed set of test functions and may fail to capture important aspects of the solution. Adversarial estimators address this limitation by framing estimation as a game between an estimator and an adaptive critic. We…

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Winner's Curse Free Robust Mendelian Randomization with Summary Data

基于汇总数据消除赢家诅咒的稳健孟德尔随机化

In the past decade, the increased availability of genome-wide association studies summary data has popularized Mendelian Randomization (MR) for conducting causal inference. MR analyses, incorporating genetic variants as instrumental variables, are known for their robustness against reverse causation bias and unmeasured confounders. Nevertheless, classical MR analyses utilizing summary data may still produce biased causal effect estimates due to the winner's curse and…

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Factor Informed Double Deep Learning For Average Treatment Effect Estimation

用于平均处理效应估计的因子辅助双重深度学习

We investigate the problem of estimating the average treatment effect (ATE) under a very general setup where the covariates can be high-dimensional, highly correlated, and can have sparse nonlinear effects on the propensity and outcome models. We present the use of a Double Deep Learning strategy for estimation, which involves combining recently developed factor-augmented deep learning-based estimators, FAST-NN, for both the response functions and propensity scores to…

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Challenges in Statistics: A Dozen Challenges in Causality and Causal Inference

统计学的挑战:因果关系与因果推断的十二项挑战

Causality and causal inference have emerged as core research areas at the interface of modern statistics and domains including biomedical sciences, social sciences, computer science, and beyond. The field's inherently interdisciplinary nature -- particularly the central role of incorporating domain knowledge -- creates a rich and varied set of statistical challenges. Much progress has been made, especially in the last three decades, but there remain many open questions. Our…

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