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postcard: An R Package for Marginal Effect Estimation with or without Prognostic Score Adjustment

postcard:支持预后评分调整的边际效应估计 R 包

Covariate adjustment is a widely used technique in randomized clinical trials (RCTs) for improving the efficiency of treatment effect estimators. By adjusting for predictive baseline covariates, variance can be reduced, enhancing statistical precision and study power. Rosenblum and van der Laan [2010] use the framework of generalized linear models (GLMs) in a plug-in analysis to show efficiency gains using covariate adjustment for marginal effect estimation. Recently the use…

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Deep learning based doubly robust test for Granger causality

基于深度学习的双重稳健格兰杰因果检验

Granger causality is popular for analyzing time series data in many applications from natural science to social science including genomics, neuroscience, economics, and finance. Consequently, the Granger causality test has become one of the main concerns of the econometrician for decades. Taking advantage of the theoretical breakthroughs in deep learning in recent years, we propose a doubly robust Granger causality test (DRGCT). Our method offers several key advantages. The…

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Autoregressive models for panel data causal inference with application to state-level opioid policies

面板因果推断中的自回归模型:州级阿片类药物政策应用

Motivated by the study of state opioid policies, we propose a novel approach that uses autoregressive models for causal effect estimation in settings with panel data and staggered treatment adoption. Specifically, we seek to estimate the impact of key opioid-related policies by quantifying the effects of must access prescription drug monitoring programs (PDMPs), naloxone access laws (NALs), and medical marijuana laws on opioid prescribing. Existing methods, such as…

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Modeling Dependence in Omics Association Analysis via Structured Co-Expression Networks to Improve Power and Replicability

利用结构化共表达网络建模组学关联分析中的依赖性以提升检验功效与可重复性

Accounting for dependence among high-dimensional variables in omics data analysis is critical to obtain accurate and reliable statistical inference. Although latent, omics variables often exhibit structured correlation/co-expression patterns. However, there are few methods explicitly accounting for such structured dependence in the statistical analysis of omics data (e.g., differential expression analysis). To address this methodological gap, we propose a Co-expression…

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Identification and Estimation of Joint Potential Outcome Distributions from a Single Study

从单项研究识别与估计潜在结果的联合分布

Most causal inference methods focus on estimating marginal average treatment effects, but many important causal estimands depend on the joint distribution of potential outcomes, including the probability of causation and proportions benefiting from or harmed by treatment. Wu et al (2025) recently established nonparametric identification of this joint distribution for categorical outcomes under binary treatment by leveraging variation across multiple studies. We demonstrate…

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Causal inference of post-transcriptional regulation timelines from long-read sequencing in Arabidopsis thaliana

利用拟南芥长读长测序推断转录后调控时间线

We propose a novel framework for reconstructing the chronology of genetic regulation using causal inference based on Pearl's theory. The approach proceeds in three main stages: causal discovery, causal inference, and chronology construction. We apply it to the ndhB and ndhD genes of the chloroplast in Arabidopsis thaliana, generating four alternative maturation timeline models per gene, each derived from a different causal discovery algorithm (HC, PC, LiNGAM, or NOTEARS).…

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Regularized Sparse Optimal Discriminant Clustering

正则化稀疏最优判别聚类

We propose a new method based on sparse optimal discriminant clustering (SODC), incorporating a penalty term into the scoring matrix based on convex clustering. With the addition of this penalty term, it is expected to improve the accuracy of cluster identification by pulling points within the same cluster closer together and points from different clusters further apart. When the estimation results are visualized, the clustering structure can be depicted more clearly.…

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Finite-Sample Distortion in Kernel Specification Tests: A Perturbation Analysis of Empirical Directional Components

核设定检验的有限样本失真:经验方向分量的扰动分析

This paper provides a new theoretical lens for understanding the finite-sample performance of kernel-based specification tests, such as the Kernel Conditional Moment (KCM) test. Rather than introducing a fundamentally new test, we isolate and rigorously analyze the finite-sample distortion arising from the discrepancy between the empirical and population eigenspaces of the kernel operator. Using perturbation theory for compact operators, we demonstrate that the estimation…

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Almost Dominance: Inference and Application

近似占优关系:统计推断与应用

This paper proposes a general framework for inference on three types of almost dominances: almost Lorenz dominance, almost inverse stochastic dominance, and almost stochastic dominance. We first generalize almost Lorenz dominance to almost upward and downward Lorenz dominances. We then provide a bootstrap inference procedure for the Lorenz dominance coefficients, which measure the degrees of almost Lorenz dominance. Furthermore, we propose almost upward and downward inverse…

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Effective regions and kernels in continuous sparse regularisation, with application to sketched mixtures

连续稀疏正则化中的有效区域与核:在草图混合模型中的应用

This paper advances the general theory of continuous sparse regularisation on measures with the Beurling-LASSO (BLASSO). This TV-regularised convex program on the space of measures allows to recover a sparse measure using a noisy observation from a measurement operator. While previous works have uncovered the central role played by this operator and its associated kernel in order to get estimation error bounds, the latter requires a technical local positive curvature (LPC)…

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Optimal break tests for large linear time series models

大型线性时间序列模型中的最优结构突变检验

We develop a class of optimal tests for a structural break occurring at an unknown date in infinite and growing-order time series regression models, such as AR($\infty$), linear regression with increasingly many covariates, and nonparametric regression. Under an auxiliary i.i.d. Gaussian error assumption, we derive an average power optimal test, establishing a growing-dimensional analog of the exponential tests of Andrews and Ploberger (1994) to handle identification failure…

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Interactive, Grouped and Non-separable Fixed Effects: A Practitioner's Guide to the New Panel Data Econometrics

交互、分组与非可分固定效应:新面板计量方法的实践指南

The past 20 years have brought fundamental advances in modeling unobserved heterogeneity in panel data. Interactive Fixed Effects (IFE) proved to be a foundational framework, generalizing the standard one-way and two-way fixed effects models by allowing the unit-specific unobserved heterogeneity to be interacted with unobserved time-varying common factors, allowing for more general forms of omitted variables. The IFE framework laid the theoretical foundations for other forms…

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L2-relaxation for Economic Prediction

经济预测中的L2松弛方法

We leverage an ensemble of many regressors, the number of which can exceed the sample size, for economic prediction. An underlying latent factor structure implies a dense regression model with highly correlated covariates. We propose the L2-relaxation method for estimating the regression coefficients and extrapolating the out-of-sample (OOS) outcomes. This framework can be applied to policy evaluation using the panel data approach (PDA), where we further establish inference…

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Constrained Identifiability of Causal Effects

约束条件下因果效应的可识别性

We study the identification of causal effects in the presence of different types of constraints (e.g., logical constraints) in addition to the causal graph. These constraints impose restrictions on the models (parameterizations) induced by the causal graph, reducing the set of models considered by the identifiability problem. We formalize the notion of constrained identifiability, which takes a set of constraints as another input to the classical definition of…

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Gaussian Approximation for High-Dimensional $U$-statistics with Size-Dependent Kernels

样本量依赖核的高维U统计量高斯近似

Motivated by small bandwidth asymptotics for kernel-based semiparametric estimators in econometrics, this paper establishes Gaussian approximation results for high-dimensional fixed-order $U$-statistics whose kernels depend on the sample size. Our results allow for a situation where the dominant component of the Hoeffding decomposition is absent or unknown, including cases with known degrees of degeneracy as special forms. The obtained error bounds for Gaussian…

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Disentangling network dependence among multiple variables

分离多个变量之间的共同网络依赖

When two variables depend on the same or similar underlying network, their shared network dependence structure can lead to spurious associations. While statistical associations between two variables sampled from interconnected subjects are a common inferential goal across various fields, little research has focused on how to disentangle shared dependence for valid statistical inference. We revisit two different approaches from distinct fields that may address shared network…

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The Power of Prognosis: Improving Covariate Balance Tests with Outcome Information

预后信息的力量:利用结局信息改进协变量平衡检验

Scholars frequently use covariate balance tests to test the validity of natural experiments and related designs. Unfortunately, when measured covariates are unrelated to potential outcomes, balance is uninformative about key identification conditions. We show that balance tests can then lead to erroneous conclusions. To build stronger tests, researchers should identify covariates that are jointly predictive of potential outcomes; formally measure and report covariate…

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Developing an information criterion for spatial data analysis through Bayesian generalized fused lasso

面向空间数据分析的贝叶斯广义融合套索信息准则

In the field of spatial data analysis, spatially varying coefficients (SVC) models, which allow regression coefficients to vary by region and flexibly capture spatial heterogeneity, have continued to be developed in various directions. Moreover, the Bayesian generalized fused lasso is often used as a method that efficiently provides estimation under the natural assumption that regression coefficients of adjacent regions tend to take the same value. In most Bayesian methods,…

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Macroeconomic Forecasting and Machine Learning

宏观经济预测与机器学习

We forecast the full conditional distribution of macroeconomic outcomes by systematically integrating three key principles: using high-dimensional data with appropriate regularization, adopting rigorous out-of-sample validation procedures, and incorporating nonlinearities. By exploiting the rich information embedded in a large set of macroeconomic and financial predictors, we produce accurate predictions of the entire profile of macroeconomic risk in real time. Our findings…

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Dimension Reduction for Conditional Density Estimation with Applications to High-Dimensional Causal Inference

条件密度估计的降维及其在高维因果推断中的应用

We propose a novel and computationally efficient approach for nonparametric conditional density estimation in high-dimensional settings that achieves dimension reduction without imposing restrictive distributional or functional form assumptions. To uncover the underlying sparsity structure of the data, we develop an innovative conditional dependence measure and a modified cross-validation procedure that enables data-driven variable selection, thereby circumventing the need…

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Partial Identification of Mean Achievement in ILSA Studies with Multi-Stage Stratified Sample Design and Student Non-Participation

多阶段分层抽样与学生未参与下国际大型测评平均成绩的部分识别

International large-scale assessment (ILSA) studies collect information across education systems with the objective of learning about the population-wide distribution of student achievement in the assessment. In this article, we study one of the most fundamental threats that these studies face when justifying the conclusions reached about these distributions: the identification problem that arises from student non-participation during data collection. Recognizing that ILSA…

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Denoised IPW-Lasso for Heterogeneous Treatment Effect Estimation in Randomized Experiments

随机实验异质性处理效应估计的去噪IPW-Lasso方法

This paper proposes a new method for estimating conditional average treatment effects (CATE) in randomized experiments. We adopt inverse probability weighting (IPW) for identification; however, IPW-transformed outcomes are known to be noisy, even when true propensity scores are used. To address this issue, we introduce a noise reduction procedure and estimate a linear CATE model using Lasso, achieving both accuracy and interpretability. We theoretically show that denoising…

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Identification and Estimation of Heterogeneous Interference Effects under Unknown Network

未知网络下异质性干扰效应的识别与估计

Interference--in which a unit's outcome is affected by the treatment of other units--poses significant challenges for the identification and estimation of causal effects. Most existing methods for estimating interference effects assume that the interference networks are known. In many practical settings, this assumption is unrealistic as such networks are typically latent. To address this challenge, we propose a novel framework for identifying and estimating heterogeneous…

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Density-valued time series: Nonparametric density-on-density regression

密度值时间序列:非参数密度对密度回归

This paper is concerned with forecasting probability density functions. Density functions are nonnegative and have a constrained integral; thus, they do not constitute a vector space. Implementing unconstrained functional time-series forecasting methods is problematic for such nonlinear and constrained data. A novel forecasting method is developed based on a nonparametric function-on-function regression, where both the response and the predictor are probability density…

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