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Finite-Sample Risk Approximation and Risk-Consistent Tuning for Generalized Ridge Estimation in Nonlinear Models: Controlling Extreme Realizations

非线性模型中广义岭估计的有限样本风险近似与风险一致调参

Maximum likelihood estimation in nonlinear models can exhibit substantial instability in finite samples when the data provide limited information about certain parameters. Such instability is driven by rare but extreme realizations of the estimator, which can dominate mean squared error (MSE) and lead to poor performance of conventional estimators. To address this issue, we consider ridge estimators that directly target MSE through regularization and thereby control extreme…

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Robust Spatial-Sign-Based Testing of High-Dimensional Alpha in Conditional Factor Models

条件因子模型中高维 Alpha 的稳健空间符号检验

This paper develops a new framework for alpha testing in high-dimensional factor pricing models with time-varying coefficients. To detect sparse alternatives, we propose a spatial-sign-based max-type test and derive its limiting null distribution. A key theoretical result is that our statistic is asymptotically independent of the spatial-sign-based sum-type test proposed by Zhao (2023). Exploiting this independence, we construct an adaptive testing procedure via the Cauchy…

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Quantifying structural uncertainty in chemical reaction network inference

量化化学反应网络推断中的结构不确定性

Dynamical systems in biology are complex, and one often does not have comprehensive knowledge about the interactions involved. Chemical reaction network (CRN) inference aims to identify, from observing species concentrations over time, the unknown reactions between the species. Existing approaches such as sparse regularisation largely focus on identifying a single, most likely CRN, without addressing uncertainty about the network structure. However, it is important to…

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Causal inference for spatiotemporal point processes in the presence of outcome spillover and carryover

存在结果溢出与延续效应时的时空点过程因果推断

We develop a framework for causal inference with continuous spatiotemporal point-process outcomes under cell-level interventions and outcome spillover. Potential outcomes are indexed by full treatment allocations, and the observed post-treatment process is represented as an unlabelled superposition of latent control and treatment components. On the observed design support, expected post-treatment event counts in any spacetime region under a given treatment allocation are…

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Sharp Hybrid Confidence Bands for Partially Identified Treatment Effects under Tail Uncertainty with an Application to Workforce Gender Diversity and Firm Performance

尾部不确定性下部分识别处理效应的混合置信带及企业性别多样性应用

Manski's nonparametric bounds partially identify the average treatment effects (ATEs) under minimal assumptions, yielding an interval-valued estimand with endpoints that depend on the outcome support - typically treated as known or fixed. In many empirical settings, however, credible bounds on the outcome support are often unavailable and outcomes may be heavy-tailed, so common empirical implementations that rely on ad-hoc truncation or observed extrema can compromise…

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Convolutional Maximum Mean Discrepancy for Inference in Noisy Data

卷积最大均值差异:噪声数据中的推断

Modern data analyses frequently encounter settings where samples of variables are contaminated by measurement error. Ignoring measurement noise can substantially degrade statistical inference, while existing correction techniques are often computationally costly and inefficient. Recent advances in kernel methods, particularly those based on Maximum Mean Discrepancy (MMD), have enabled flexible, distribution-free inference, yet typically assume precise data and overlook…

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Inferring Change Points in Regression via Sample Weighting

通过样本加权推断回归中的变点

We study the problem of identifying change points in high-dimensional generalized linear models, and propose an approach based on sample-weighted empirical risk minimization. Our method, Weighted ERM, encodes priors on the change points via weights assigned to each sample, to obtain weighted versions of standard estimators such as M-estimators and maximum-likelihood estimators. Under mild assumptions on the data, we obtain a precise asymptotic characterization of the…

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Principled Inference in Dense High-Dimensional Linear Models via Local Conditional Sparsity

基于局部条件稀疏性的稠密高维线性模型原则化推断

High-dimensional inference methods often rely on coefficient sparsity, an assumption that can be restrictive when signals are dense but individually weak. In such settings, valid inference may still be possible if the covariates exhibit sparse conditional dependence. Motivated by this observation, we propose Neighborhood-Localized Nested Regression (NLNR), a framework for coordinatewise inference in high-dimensional linear models with potentially dense coefficients. The…

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Average Marginal Effects in One-Step Partially Linear Instrumental Regressions

一步部分线性工具变量回归中的平均边际效应

We propose a novel procedure for estimating and conducting inference on average marginal effects in partially linear instrumental regressions using Reproducing Kernel Hilbert Space methods. Our procedure relies on a single regularization parameter. We obtain the consistency and asymptotic normality of our estimator. Since the variance of the limiting distribution has a complex analytical form, we propose a Bayesian bootstrap method to conduct inference and establish its…

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Detecting critical treatment effect bias in small subgroups

小子群中关键处理效应偏差的检测

Randomized trials are considered the gold standard for making informed decisions in medicine, yet they often lack generalizability to the patient populations in clinical practice. Observational studies, on the other hand, cover a broader patient population but are prone to various biases. Thus, before using an observational study for decision-making, it is crucial to benchmark its treatment effect estimates against those derived from a randomized trial. We propose a novel…

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Prediction decomposition for causal analysis

用于因果分析的预测分解

There is rising interest in using Machine Learning (ML) model predictions as outcomes in causal analysis. However, these methods have faced challenges in finding the true treatment effects. It is also challenging to make choices about which prediction models to choose, since we are interested not only in the accuracy of the prediction but in its ability to produce the correct causal effect in the analysis. In this paper I propose a decomposition of the prediction into…

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Quantifying Individual Risk for Binary Outcomes

二元结果下的个体风险量化

Understanding treatment effect heterogeneity is crucial for reliable decision-making in treatment evaluation and selection. The conditional average treatment effect (CATE) is widely used to capture treatment effect heterogeneity induced by observed covariates and to design individualized treatment policies. However, it is an average metric within subpopulations, which prevents it from revealing individual risk, potentially leading to misleading results. This article fills…

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A Strict Gap Between Relaxed and Partition-Constrained Spectral Compression in a Six-State Lumpable Markov Chain

六状态可聚合马尔可夫链中松弛谱压缩与分割约束压缩的严格差距

This paper studies a finite reversible lumpable Markov chain for which relaxed spectral compression yields a larger determinant than partition-constrained compression. For a symmetric six-state lumpable chain and the positive operator $T=P^2$, I compare the relaxed benchmark \begin{equation*} \mathfrak D^{\mathrm{rel}}_3(T):=\sup_{U^*U=I_3}\det(U^*TU) \end{equation*} and the partition-constrained benchmark \begin{equation*} \sup_{\mathcal A\,\mathrm{3\text{-}partition}}\det Q_{\mathcal A}(T), \qquad Q_{\mathcal A}(T)=H_{\mathcal A}^*TH_{\mathcal A}. \end{equation*}…

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Variable-Length Markov Chains on Finite Quivers: Boundary-Window Identifiability, Exact Depth, and Local Rank Comparison

有限箭图上的变长马尔可夫链:边界窗口识别、精确深度与局部秩比较

Variable-length Markov chains on finite quivers provide a natural framework for context-dependent stochastic growth under incidence constraints. I study quiver-valued variable-length Markov chains observed through finite boundary windows and develop a first-order theory of visible-depth identifiability via stationary visible one-step transition laws and their restricted differentials on prescribed tangent blocks. For visible depth $m$, the main object is the stationary…

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Econometric Inference with Machine-Learned Proxies: Partial Identification via Data Combination

机器学习代理变量下的计量推断:通过数据组合实现部分识别

Empirical researchers increasingly use upstream machine-learning (ML) methods to construct proxies for latent target variables from complex, unstructured data. A naive plug-in use of such proxies in downstream econometric models, however, can lead to biased estimation and invalid inference. This paper develops a framework for partial identification and inference in general moment models with ML-generated proxies. Our approach does not require restrictive assumptions on the…

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Causal mediation in cluster-randomized trials with multiple mediators: spillover-aware decomposition, identification, and semiparametric efficient inference

多中介整群随机试验的因果中介分析:溢出分解、识别与有效推断

Causal mediation analysis in cluster-randomized trials (CRTs) is complicated by the presence of multiple mediators, intracluster correlation, and within-cluster interference. Existing mediation methods often fall short in accommodating these features simultaneously, and semiparametric efficient estimators that fully address them remain unavailable. We develop a unified framework that defines a class of mediation effect estimands, including exit indirect effects, exit…

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Transfer Learning for Moderate-Dimensional Ridge-Regularized Robust Linear Regression

中等维度岭正则化稳健线性回归的迁移学习

This paper studies transfer learning for ridge-regularized robust linear regression in the moderate-dimensional regime, where the number of predictors is of the same order as the sample size and the regression coefficients are not assumed to be sparse. We propose Trans-RR, which combines a robust ridge estimator from a source study with a robust ridge correction based on the target study. Under mild assumptions, we characterize the asymptotic estimation error of the proposed…

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Orthogonal machine learning for conditional odds and risk ratios

条件优势比与风险比的正交机器学习

Conditional effects are commonly used measures for understanding how treatment effects vary across different groups, and are often used to target treatments/interventions to groups who benefit most. In this work we review existing methods and propose novel ones, focusing on the odds ratio (OR) and the risk ratio (RR). While estimation of the conditional average treatment effect (ATE) has been widely studied, estimators for the OR and RR lag behind, and cutting edge…

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Estimating heterogeneous treatment effects with survival outcomes via a deep survival learner

利用深度生存学习器估计生存结局的异质性处理效应

Estimating heterogeneous treatment effects in survival settings is complicated by right censoring as well as the time-varying nature of the estimand. While the conditional average treatment effect (CATE) provides a natural target, most existing approaches focus on a single prespecified time point and do not account for the temporal trajectory, leading to instability in estimation. We propose a deep survival learner (DSL) for estimating heterogeneous treatment effects with…

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Gaussian Graphical Models for Functional Connectivity Analysis: A Statistical Review with Applications to Alzheimer's Disease

高斯图模型用于功能连接分析:面向阿尔茨海默病的统计综述

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a promising statistical framework for estimating functional connectivity by capturing conditional dependence relationships among brain regions. Although a variety of regularized precision matrix estimators have been proposed to estimate…

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crumble: A comprehensive framework for modern causal mediation analysis with intermediate confounding

crumble:存在中间混杂时的现代因果中介分析框架

Causal mediation analysis is widely used to investigate how causal effects operate through specific pathways linking treatments or exposures to outcomes. Recently, \texttt{crumble} was developed to enable nonparametric estimation of several mediation parameters, even when mediators are continuous and/or multi-dimensional or when treatments are non-binary. But a practical and accessible guide to using \texttt{crumble} -- one that does not require deep familiarity with…

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Differentially Private Estimation and Inference in High-Dimensional Regression with FDR Control

高维回归中的差分隐私估计与推断及FDR控制

This paper proposes new methodologies for conducting practical differentially private (DP) estimation and inference in high-dimensional linear regression. We first introduce a DP Bayesian Information Criterion (DP-BIC) for selecting the unknown sparsity parameter in differentially private sparse linear regression (DP-SLR), eliminating the need for prior knowledge of model sparsity, which is a requisite in the existing literature. Next, we develop the DP debiased algorithm…

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The Cascade Identity: 2SLS as a Policy Parameter in Capacity-Constrained Settings

级联恒等式:容量约束情境下作为政策参数的 2SLS

Governments routinely adjust capacity in rationed programs such as university fields, medical training and public housing, where admitting one individual displaces others and triggers chains of reallocation. We show that in such settings, the standard multi-treatment two-stage least squares (2SLS) coefficient identifies exactly the total societal effect of a marginal expansion, including all downstream reallocations. The result is an algebraic identity: under instrument…

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Large SVARs

大型结构向量自回归模型

We develop a new algorithm for inference in structural vector autoregressions (SVARs) identified with sign restrictions that can accommodate big data and modern identification schemes. The key innovation of our approach is to move beyond the traditional accept-reject framework commonly used in sign-identified SVARs. We show that an elliptical slice within Gibbs sampler can deliver dramatic gains in computational speed and render previously infeasible applications tractable.…

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