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Sensitivity Analysis for Marginal Structural Models

边际结构模型的敏感性分析

We introduce several methods for assessing sensitivity to unmeasured confounding in marginal structural models; importantly we allow treatments to be discrete or continuous, static or time-varying. We consider three sensitivity models: a propensity-based model, an outcome-based model, and a subset confounding model, in which only a fraction of the population is subject to unmeasured confounding. In each case we develop efficient estimators and confidence intervals for bounds…

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Robust multiscale estimation of time-average variance for time series segmentation

用于时间序列分段的稳健多尺度时间平均方差估计

There exist several methods developed for the canonical change point problem of detecting multiple mean shifts, which search for changes over sections of the data at multiple scales. In such methods, estimation of the noise level is often required in order to distinguish genuine changes from random fluctuations due to the noise. When serial dependence is present, using a single estimator of the noise level may not be appropriate. Instead, it is proposed to adopt a…

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Weighted hazard ratio estimation for delayed and diminishing treatment effect

延迟及递减处理效应下的加权风险比估计

Non-proportional hazards (NPH) have been observed in confirmatory clinical trials with time to event outcomes. Under NPH, the hazard ratio does not stay constant over time and the log-rank test is no longer the most powerful test. The weighted log-rank test (WLRT) has been introduced to deal with the presence of non-proportionality. We focus our attention on the WLRT and the complementary Cox model based on the time-varying treatment effect proposed by Lin and León (2017)…

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A Generalized Argmax Theorem with Applications

广义最大值点定理及其应用

The argmax theorem is a useful result for deriving the limiting distribution of estimators in many applications. The conclusion of the argmax theorem states that the argmax of a sequence of stochastic processes converges in distribution to the argmax of a limiting stochastic process. This paper generalizes the argmax theorem to allow the maximization to take place over a sequence of subsets of the domain. If the sequence of subsets converges to a limiting subset, then the…

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Segmenting Time Series via Self-Normalization

通过自归一化分割时间序列

We propose a novel and unified framework for change-point estimation in multivariate time series. The proposed method is fully nonparametric, enjoys effortless tuning and is robust to temporal dependence. One salient and distinct feature of the proposed method is its versatility, where it allows change-point detection for a broad class of parameters (such as mean, variance, correlation and quantile) in a unified fashion. At the core of our method, we couple the…

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On the asymptotic behavior of bubble date estimators

泡沫日期估计量的渐近行为

In this study, we extend the three-regime bubble model of Pang et al. (2021) to allow the forth regime followed by the unit root process after recovery. We provide the asymptotic and finite sample justification of the consistency of the collapse date estimator in the two-regime AR(1) model. The consistency allows us to split the sample before and after the date of collapse and to consider the estimation of the date of exuberation and date of recovery separately. We have also…

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Tree-based Subgroup Discovery In Electronic Health Records: Heterogeneity of Treatment Effects for DTG-containing Therapies

电子健康记录中的树式亚组发现:含 DTG 疗法的治疗效应异质性

The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment effects using EHR data poses several challenges, including time-varying confounding, repeated and temporally non-aligned measurements of covariates, treatment assignments and outcomes, and loss-to-follow-up due to dropout. Here, we develop the Subgroup Discovery for Longitudinal Data (SDLD) algorithm,…

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Assessing the causal effects of a stochastic intervention in time series data: Are heat alerts effective in preventing deaths and hospitalizations?

时间序列中随机干预的因果效应:高温预警能否减少死亡和住院?

The methodological development of this paper is motivated by the need to address the following scientific question: does the issuance of heat alerts prevent adverse health effects? Our goal is to address this question within a causal inference framework in the context of time series data. A key challenge is that causal inference methods require the overlap assumption to hold: each unit (i.e., a day) must have a positive probability of receiving the treatment (i.e., issuing a…

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A Practical Guide to Counterfactual Estimators for Causal Inference with Time-Series Cross-Sectional Data

时间序列截面数据因果推断的反事实估计实用指南

This paper introduces a simple framework of counterfactual estimation for causal inference with time-series cross-sectional data, in which we estimate the average treatment effect on the treated by directly imputing counterfactual outcomes for treated observations. We discuss several novel estimators under this framework, including the fixed effects counterfactual estimator, interactive fixed effects counterfactual estimator, and matrix completion estimator. They provide…

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Detecting frequency modulation in stochastic time series data

随机时间序列中的频率调制检测

We propose a new statistical test to identify non-stationary frequency-modulated stochastic processes from time series data. Our method uses the instantaneous phase as a discriminatory statistics with reliable critical values derived from surrogate data. We simulated an oscillatory second-order autoregressive process to evaluate the size and power of the test. We found that the test we propose is able to correctly identify more than 99% of non-stationary data when the…

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Proximal Causal Inference for Complex Longitudinal Studies

复杂纵向研究中的近端因果推断

A standard assumption for causal inference about the joint effects of time-varying treatment is that one has measured sufficient covariates to ensure that within covariate strata, subjects are exchangeable across observed treatment values, also known as "sequential randomization assumption (SRA)". SRA is often criticized as it requires one to accurately measure all confounders. Realistically, measured covariates can rarely capture all confounders with certainty. Often…

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Concentration inequalities for correlated network-valued processes with applications to community estimation and changepoint analysis

相关网络值过程的集中不等式及其社区与变点估计应用

Network-valued time series are currently a common form of network data. However, the study of the aggregate behavior of network sequences generated from network-valued stochastic processes is relatively rare. Most of the existing research focuses on the simple setup where the networks are independent (or conditionally independent) across time, and all edges are updated synchronously at each time step. In this paper, we study the concentration properties of the aggregated…

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A penalized two-pass regression to predict stock returns with time-varying risk premia

利用时变风险溢价预测股票收益的惩罚两步回归

We develop a penalized two-pass regression with time-varying factor loadings. The penalization in the first pass enforces sparsity for the time-variation drivers while also maintaining compatibility with the no-arbitrage restrictions by regularizing appropriate groups of coefficients. The second pass delivers risk premia estimates to predict equity excess returns. Our Monte Carlo results and our empirical results on a large cross-sectional data set of US individual stocks…

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Interpreting and predicting the economy flows: A time-varying parameter global vector autoregressive integrated the machine learning model

融合机器学习的时变参数全球向量自回归:经济动态解释与预测

The paper proposes a time-varying parameter global vector autoregressive (TVP-GVAR) framework for predicting and analysing developed region economic variables. We want to provide an easily accessible approach for the economy application settings, where a variety of machine learning models can be incorporated for out-of-sample prediction. The LASSO-type technique for numerically efficient model selection of mean squared errors (MSEs) is selected. We show the convincing…

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Modelling Time-Varying Rankings with Autoregressive and Score-Driven Dynamics

结合自回归与得分驱动动态的时变排名模型

We develop a new statistical model to analyse time-varying ranking data. The model can be used with a large number of ranked items, accommodates exogenous time-varying covariates and partial rankings, and is estimated via the maximum likelihood in a straightforward manner. Rankings are modelled using the Plackett-Luce distribution with time-varying worth parameters that follow a mean-reverting time series process. To capture the dependence of the worth parameters on past…

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Sparse Bayesian State-Space and Time-Varying Parameter Models

稀疏贝叶斯状态空间与时变参数模型

In this chapter, we review variance selection for time-varying parameter (TVP) models for univariate and multivariate time series within a Bayesian framework. We show how both continuous as well as discrete spike-and-slab shrinkage priors can be transferred from variable selection for regression models to variance selection for TVP models by using a non-centered parametrization. We discuss efficient MCMC estimation and provide an application to US inflation modeling.

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Time-Varying Poisson Autoregression

时变泊松自回归

In this paper we propose a new time-varying econometric model, called Time-Varying Poisson AutoRegressive with eXogenous covariates (TV-PARX), suited to model and forecast time series of counts. {We show that the score-driven framework is particularly suitable to recover the evolution of time-varying parameters and provides the required flexibility to model and forecast time series of counts characterized by convoluted nonlinear dynamics and structural breaks.} We study the…

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Greykite: Deploying Flexible Forecasting at Scale at LinkedIn

Greykite:在 LinkedIn 大规模部署灵活预测

Forecasts help businesses allocate resources and achieve objectives. At LinkedIn, product owners use forecasts to set business targets, track outlook, and monitor health. Engineers use forecasts to efficiently provision hardware. Developing a forecasting solution to meet these needs requires accurate and interpretable forecasts on diverse time series with sub-hourly to quarterly frequencies. We present Greykite, an open-source Python library for forecasting that has been…

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Data Segmentation for Time Series Based on a General Moving Sum Approach

基于一般移动和方法的时间序列分段

In this paper we propose new methodology for the data segmentation, also known as multiple change point problem, in a general framework including classic mean change scenarios, changes in linear regression but also changes in the time series structure such as in the parameters of Poisson-autoregressive time series. In particular, we derive a general theory based on estimating equations proving consistency for the number of change points as well as rates of convergence for…

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Distribution-free changepoint detection tests based on the breaking of records

基于破纪录事件的分布无关变点检验

The analysis of record-breaking events is of interest in fields such as climatology, hydrology or anthropology. In connection with the record occurrence, we propose three distribution-free statistics for the changepoint detection problem. They are CUSUM-type statistics based on the upper and/or lower record indicators observed in a series. Using a version of the functional central limit theorem, we show that the CUSUM-type statistics are asymptotically Kolmogorov…

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Parametric change point detection with random occurrence of the change point

变点位置随机出现时的参数变点检测

We are concerned with the problem of detecting a single change point in the model parameters of time series data generated from an exponential family. In contrast to the existing literature, we allow that the true location of the change point is itself random, possibly depending on the data. Under the alternative, we study the case when the size of the change point converges to zero while the sample size goes to infinity. Moreover, we concentrate on change points in the…

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Bayesian Circular Lattice Filters for Computationally Efficient Estimation of Multivariate Time-Varying Autoregressive Models

用于高效估计多元时变自回归模型的贝叶斯循环格型滤波器

Nonstationary time series data exist in various scientific disciplines, including environmental science, biology, signal processing, econometrics, among others. Many Bayesian models have been developed to handle nonstationary time series. The time-varying vector autoregressive (TV-VAR) model is a well-established model for multivariate nonstationary time series. Nevertheless, in most cases, the large number of parameters presented by the model results in a high computational…

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Offline Change Detection under Contamination

污染数据下的离线变点检测

In this work, we propose a non-parametric and robust change detection algorithm to detect multiple change points in time series data under contamination. The contamination model is sufficiently general, in that, the most common model used in the context of change detection -- Huber contamination model -- is a special case. Also, the contamination model is oblivious and arbitrary. The change detection algorithm is designed for the offline setting, where the objective is to…

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Doubly-online changepoint detection for monitoring health status during sports activities

运动健康状态监测的双重在线变点检测

We provide an online framework for analyzing data recorded by smart watches during running activities. In particular, we focus on identifying variations in the behavior of one or more measurements caused by changes in physical condition, such as physical discomfort, periods of prolonged de-training, or even the malfunction of measuring devices. Our framework considers data as a sequence of running activities represented by multivariate time series of physical and biometric…

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