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A Predictor-Informed Multi-Subject Bayesian Approach for Dynamic Functional Connectivity

融合预测变量的多受试者动态功能连接贝叶斯方法

Time Varying Functional Connectivity (TVFC) investigates how the interactions among brain regions vary over the course of an fMRI experiment. The transitions between different individual connectivity states can be modulated by changes in underlying physiological mechanisms that drive functional network dynamics, e.g., changes in attention or cognitive effort as measured by pupil dilation. In this paper, we develop a multi-subject Bayesian framework for estimating dynamic…

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Frequency Band Analysis of Nonstationary Multivariate Time Series

非平稳多元时间序列的频带分析

Information from frequency bands in biomedical time series provides useful summaries of the observed signal. Many existing methods consider summaries of the time series obtained over a few well-known, pre-defined frequency bands of interest. However, these methods do not provide data-driven methods for identifying frequency bands that optimally summarize frequency-domain information in the time series. A new method to identify partition points in the frequency space of a…

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Granger causality test for heteroskedastic and structural-break time series using generalized least squares

异方差与结构突变时间序列的广义最小二乘 Granger 检验

This paper proposes a novel method (GLS Granger test) to determine causal relationships between time series based on the estimation of the autocovariance matrix and generalized least squares. We show the effectiveness of proposed autocovariance matrix estimator (the sliding autocovariance matrix) and we compare the proposed method with the classical Granger F-test with via a synthetic dataset and a real dataset composed by cryptocurrencies. The simulations show that the…

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Measuring tail risk at high-frequency: An $L_1$-regularized extreme value regression approach with unit-root predictors

高频尾部风险测度:含单位根预测变量的 L1 正则化极值回归

We study tail risk dynamics in high-frequency financial markets and their connection with trading activity and market uncertainty. We introduce a dynamic extreme value regression model accommodating both stationary and local unit-root predictors to appropriately capture the time-varying behaviour of the distribution of high-frequency extreme losses. To characterize trading activity and market uncertainty, we consider several volatility and liquidity predictors, and propose a…

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Inference for Low-Rank Models

低秩模型的统计推断

This paper studies inference in linear models with a high-dimensional parameter matrix that can be well-approximated by a ``spiked low-rank matrix.'' A spiked low-rank matrix has rank that grows slowly compared to its dimensions and nonzero singular values that diverge to infinity. We show that this framework covers a broad class of models of latent-variables which can accommodate matrix completion problems, factor models, varying coefficient models, and heterogeneous…

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A smooth transition autoregressive model for matrix-variate time series

矩阵值时间序列的平滑转换自回归模型

In many applications, data are observed as matrices with temporal dependence. Matrix-variate time series modeling is a new branch of econometrics. Although stylized facts in several fields, the existing models do not account for regime switches in the dynamics of matrices that are not abrupt. In this paper, we extend linear matrix-variate autoregressive models by introducing a regime-switching model capable of accounting for smooth changes, the matrix smooth transition…

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Some recent trends in embeddings of time series and dynamic networks

时间序列与动态网络嵌入的近期发展

We give a review of some recent developments in embeddings of time series and dynamic networks. We start out with traditional principal components and then look at extensions to dynamic factor models for time series. Unlike principal components for time series, the literature on time-varying nonlinear embedding is rather sparse. The most promising approaches in the literature is neural network based, and has recently performed well in forecasting competitions. We also touch…

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Individual causal effects from observational longitudinal studies with time-varying exposures

时变暴露观测性纵向研究中的个体因果效应

Causal effects may vary among individuals and can even be of opposite signs. When significant effect heterogeneity exists, the population average causal effect might be uninformative for an individual. Due to the fundamental problem of causality, individual causal effects (ICEs) cannot be retrieved from cross-sectional data. However, in crossover studies, it is accepted that ICEs can be estimated under the assumptions of no carryover effects and time invariance of potential…

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Generalized Varying Coefficient Mediation Models

广义变系数中介模型

Motivated by an analysis of causal mechanism from economic stress to entrepreneurial withdrawals through depressed affect, we develop a two-layer generalized varying coefficient mediation model. This model captures the bridging effects of mediators that may vary with another variable, by treating them as smooth functions of this variable. It also allows various response types by introducing the generalized varying coefficient model in the first layer. The varying direct and…

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Estimating Time-Varying Direct and Indirect Causal Excursion Effects with Longitudinal Binary Outcomes

纵向二元结局的时变直接与间接因果偏离效应估计

Construction of just-in-time adaptive interventions, such as prompts delivered by mobile apps to promote and maintain behavioral change, requires knowledge about time-varying moderated effects to inform when and how we deliver intervention options. Micro-randomized trials (MRT) have emerged as a sequentially randomized design to gather requisite data for effect estimation. The existing literature (Qian et al., 2020; Boruvka et al., 2018; Dempsey et al., 2020) has defined a…

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Functional estimation and change detection for nonstationary time series

非平稳时间序列的泛函估计与变化检测

Tests for structural breaks in time series should ideally be sensitive to breaks in the parameter of interest, while being robust to nuisance changes. Statistical analysis thus needs to allow for some form of nonstationarity under the null hypothesis of no change. In this paper, estimators for integrated parameters of locally stationary time series are constructed and a corresponding functional central limit theorem is established, enabling change-point inference for a broad…

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Detecting Abrupt Changes in Sequential Pairwise Comparison Data

序贯成对比较数据中突变的检测

The Bradley-Terry-Luce (BTL) model is a classic and very popular statistical approach for eliciting a global ranking among a collection of items using pairwise comparison data. In applications in which the comparison outcomes are observed as a time series, it is often the case that data are non-stationary, in the sense that the true underlying ranking changes over time. In this paper we are concerned with localizing the change points in a high-dimensional BTL model with…

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Causal identification for continuous-time stochastic processes

连续时间随机过程的因果识别

Many real-world processes are trajectories that may be regarded as continuous-time "functional data". Examples include patients' biomarker concentrations, environmental pollutant levels, and prices of stocks. Corresponding advances in data collection have yielded near continuous-time measurements, from e.g. physiological monitors, wearable digital devices, and environmental sensors. Statistical methodology for estimating the causal effect of a time-varying treatment,…

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Projection inference for high-dimensional covariance matrices with structured shrinkage targets

结构化收缩目标下高维协方差矩阵的投影推断

Analyzing large samples of high-dimensional data under dependence is a challenging statistical problem as long time series may have change points, most importantly in the mean and the marginal covariances, for which one needs valid tests. Inference for large covariance matrices is especially difficult due to noise accumulation, resulting in singular estimates and poor power of related tests. The singularity of the sample covariance matrix in high dimensions can be overcome…

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Bias of the additive hazard model in the presence of causal effect heterogeneity

因果效应异质性下加性风险模型的偏差

Hazard ratios are prone to selection bias, compromising their use as causal estimands. On the other hand, the hazard difference has been shown to remain unaffected by the selection of frailty factors over time. Therefore, observed hazard differences can be used as an unbiased estimator for the causal hazard differences in the absence of confounding. However, in the presence of effect (on the hazard) heterogeneity, the hazard difference is also affected by selection. In this…

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Dynamic Survival Transformers for Causal Inference with Electronic Health Records

用于电子健康记录因果推断的动态生存 Transformer

In medicine, researchers often seek to infer the effects of a given treatment on patients' outcomes. However, the standard methods for causal survival analysis make simplistic assumptions about the data-generating process and cannot capture complex interactions among patient covariates. We introduce the Dynamic Survival Transformer (DynST), a deep survival model that trains on electronic health records (EHRs). Unlike previous transformers used in survival analysis, DynST can…

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Temporally Disentangled Representation Learning

时间解耦的表征学习

Recently in the field of unsupervised representation learning, strong identifiability results for disentanglement of causally-related latent variables have been established by exploiting certain side information, such as class labels, in addition to independence. However, most existing work is constrained by functional form assumptions such as independent sources or further with linear transitions, and distribution assumptions such as stationary, exponential family…

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Bayesian Causal Inference: A Critical Review

贝叶斯因果推断:批判性综述

This paper provides a critical review of the Bayesian perspective of causal inference based on the potential outcomes framework. We review the causal estimands, identification assumptions, the general structure of Bayesian inference of causal effects, and sensitivity analysis. We highlight issues that are unique to Bayesian causal inference, including the role of the propensity score, definition of identifiability, the choice of priors in both low and high dimensional…

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A Semiparametric Approach to the Detection of Change-points in Volatility Dynamics of Financial Data

金融数据波动动态变点检测的半参数方法

One of the most important features of financial time series data is volatility. There are often structural changes in volatility over time, and an accurate estimation of the volatility of financial time series requires careful identification of change-points. A common approach to modeling the volatility of time series data is the well-known GARCH model. Although the problem of change-point estimation of volatility dynamics derived from the GARCH model has been considered in…

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Bayesian estimation of the autocovariance of a model error in time series

时间序列模型误差自协方差的贝叶斯估计

Autocovariance of the error term in a time series model plays a key role in the estimation and inference for the model that it belongs to. Typically, some arbitrary parametric structure is assumed upon the error to simplify the estimation, which inevitably introduces potential model-misspecification. We thus conduct nonparametric estimation of it. To avoid the difficult bandwidth selection issue under the traditional nonparametric truncation approach, this paper conducts the…

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Fast Estimation of Bayesian State Space Models Using Amortized Simulation-Based Inference

利用摊销式模拟推断快速估计贝叶斯状态空间模型

This paper presents a fast algorithm for estimating hidden states of Bayesian state space models. The algorithm is a variation of amortized simulation-based inference algorithms, where a large number of artificial datasets are generated at the first stage, and then a flexible model is trained to predict the variables of interest. In contrast to those proposed earlier, the procedure described in this paper makes it possible to train estimators for hidden states by…

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Sensitivity Analysis for Marginal Structural Models

边际结构模型的敏感性分析

We introduce several methods for assessing sensitivity to unmeasured confounding in marginal structural models; importantly we allow treatments to be discrete or continuous, static or time-varying. We consider three sensitivity models: a propensity-based model, an outcome-based model, and a subset confounding model, in which only a fraction of the population is subject to unmeasured confounding. In each case we develop efficient estimators and confidence intervals for bounds…

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Robust multiscale estimation of time-average variance for time series segmentation

用于时间序列分段的稳健多尺度时间平均方差估计

There exist several methods developed for the canonical change point problem of detecting multiple mean shifts, which search for changes over sections of the data at multiple scales. In such methods, estimation of the noise level is often required in order to distinguish genuine changes from random fluctuations due to the noise. When serial dependence is present, using a single estimator of the noise level may not be appropriate. Instead, it is proposed to adopt a…

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Weighted hazard ratio estimation for delayed and diminishing treatment effect

延迟及递减处理效应下的加权风险比估计

Non-proportional hazards (NPH) have been observed in confirmatory clinical trials with time to event outcomes. Under NPH, the hazard ratio does not stay constant over time and the log-rank test is no longer the most powerful test. The weighted log-rank test (WLRT) has been introduced to deal with the presence of non-proportionality. We focus our attention on the WLRT and the complementary Cox model based on the time-varying treatment effect proposed by Lin and León (2017)…

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