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Semiparametric Estimation of Fractional Integration: An Evaluation of Local Whittle Methods

分数阶单整的半参数估计:局部 Whittle 方法评估

Fractionally integrated time series, exhibiting long memory with slowly decaying autocorrelations, are frequently encountered in economics, finance, and related fields. Since the seminal work of Robinson (1995), a variety of semiparametric local Whittle estimators have been proposed for estimating the memory parameter $d$, each with a distinct range of validity and different robustness properties, leaving applied researchers to decide which to use and under what conditions.…

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Modeling group heterogeneity in spatio-temporal data via physics-informed semiparametric regression

基于物理信息半参数回归的时空数据组异质性建模

In this work we propose a novel approach for modeling spatio-temporal data characterized by group structures. In particular, we extend classical mixed effect regression models by introducing a space-time nonparametric component, regularized through a partial differential equation, to embed the physical dynamics of the underlying process, while random effects capture latent variability associated with the group structure present in the data. We propose a two-step procedure to…

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Testing for correct model specification in copula regression models

Copula 回归模型设定正确性的检验

We propose a goodness-of-fit test for semiparametric copula regression models. Such models express the regression function in terms of marginal distribution functions and copula densities and therefore provide a flexible way to avoid fully nonparametric estimation in high-dimensional regression problems. Their performance, however, depends crucially on the specification of the parametric copula family. Instead of testing the copula model itself, we assess misspecification…

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Difference-in-differences with stochastic policy shifts of a continuous treatment

连续处理随机政策变动下的双重差分

Treatment effects of stochastic policy shifts quantify differences in outcomes across counterfactual scenarios with varying treatment distributions. Stochastic policy shifts may be of interest in settings where it is unrealistic or infeasible to deterministically manipulate treatments. In this paper, methods are developed to draw inference about stochastic policy effects under difference-in-differences (DiD) designs with a continuous treatment. The proposed causal estimand…

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Semiparametric Bayesian structure learning of nonparanormal directed acyclic graphs with local--global shrinkage

采用局部—全局收缩的非正态变换有向无环图半参数贝叶斯结构学习

Bayesian structure learning of directed acyclic graphs (DAGs) is central to high-dimensional causal discovery, yet existing methods mostly assume multivariate Gaussian data, which is routinely violated by measurements displaying heavy tails, skewness, or bounded support. We address this by introducing NPN-DAG-HS, a fully Bayesian semiparametric DAG model coupling the nonparanormal family with horseshoe shrinkage on Cholesky off-diagonals via an extended-rank likelihood. This…

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Robust Weighted Triangulation of Causal Effects Under Model Uncertainty

模型不确定性下因果效应的稳健加权三角验证

A fundamental challenge in causal inference with observational data is correct specification of a causal model. When there is model uncertainty, analysts may seek to use estimates from multiple candidate models that rely on distinct, and possibly partially overlapping, sets of identifying assumptions to infer the causal effect, a process known as triangulation. Principled methods for triangulation, however, remain underdeveloped. Here, we develop a framework for causal…

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Model-robust standardization in stepped wedge cluster randomized trials

阶梯楔形集群随机试验中的模型稳健标准化

Stepped-wedge cluster-randomized trials (SW-CRTs) are widely used in healthcare and implementation science, enabling all clusters to receive the intervention through a staggered rollout. Traditional model-based methods, including generalized estimating equations and mixed models, yield estimates that depend on implicit weighting schemes and parametric assumptions, and therefore may target ambiguous estimands under model misspecification. In this article, we propose a…

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Statistical inference for the probability of necessity for causal attribution

因果归因中必要性概率的统计推断

To answer questions of "causes of effects", the probability of necessity was previously introduced for assessing whether an observed outcome was caused by an earlier treatment. However, statistical inference for the probability of necessity is understudied due to several difficulties, which hinder its application in practice. The evaluation of the probability of necessity involves the joint distribution of potential outcomes, and thus it is generally not point identified and…

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Semiparametric Efficiency Theory as Differential Calculus on a Space of Probability Distributions

半参数效率理论:概率分布空间上的微分学

Semiparametric efficiency theory provides the mathematical foundation for influence-function-based estimation, including one-step estimators, targeted minimum loss estimators, and many modern inferential methods used in causal inference and missing data analysis. Despite its widespread use, the theory is often presented through a collection of technical constructions whose geometric meaning remains opaque. As a result, influence functions are often derived and applied…

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Proximal Mediation Analysis with Unmeasured Treatment-Induced Confounding

存在未测量处理诱发混杂的近端中介分析

Mediation analysis provides a central framework for elucidating causal mechanisms, yet its application is often impeded by treatment-induced confounding, under which the widely used natural mediation effects are generally unidentifiable. Interventional effects have been proposed as an alternative when these confounders are observable; however, identifying and estimating interventional effects remains challenging when confounders are unmeasured. In this paper, we address this…

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Semiparametric Efficiency in Sequential Experiments: Characterization and Design via Average Propensity

序贯实验的半参数效率:基于平均倾向得分的刻画与设计

Modern experiments, including evaluations of AI-enabled services and platform interventions, often depart from independent and identically distributed (i.i.d.) sampling because assignments may be adaptive, balanced across covariates, or subject to rollout constraints such as exposure, fairness, and budget limits. This paper studies the efficiency benchmark for estimating causal targets in such sequential experiments. We show that every non-anticipating design induces an…

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An Instrumental Variable Approach to Account for Informative Treatment Switching in Real-world Evidence

真实世界证据中信息性治疗切换的工具变量方法

Reproducible and generalizable assessment of treatment decisions requires principled handling of subsequent treatment switching that may inform expected outcomes and shift across cohorts and over time. To effectively account for informative treatment switching, we propose an instrumental variable approach that characterizes the poorly documented expected outcomes at switching as unmeasured confounding. After establishing the baseline treatment as a viable instrumental…

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Censored broken adaptive ridge rank regression via induced smoothing

基于诱导平滑的删失断崖自适应岭秩回归

Broken adaptive ridge (BAR) penalty approximates $L_0$-regularization through iterative reweighting of L2 penalties. This penalty enjoys both the oracle property and the grouping effect for highly correlated covariates, making it particularly attractive for penalized regression with complex dependence among predictors. In this paper, we develop a BAR-penalized linear rank regression method for the semiparametric accelerated failure time model with right-censored data.…

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Inferring Comprehensive Cohort Causal Effects in the Presence of Unmeasured Confounding and Missing Outcomes

未测混杂与结局缺失下的综合队列因果效应推断

This paper presents a methodological framework for estimating the comprehensive cohort causal effect (CCCE) in mixed-design clinical studies that combine randomized controlled trials (RCTs) and parallel observational study (OBS). Our approach is designed to evaluate robustness against unmeasured confounding in the OBS arm and to handle outcomes that are missing at random in either the RCT or OBS arm. By employing a semiparametric theory-based sensitivity analysis framework,…

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Choosing the threshold in extreme value analysis

极值分析中的阈值选择

One of the two dominant approaches for univariate extreme value analysis is to model exceedances above a large threshold, the choice of which has a large impact on inference and whose uncertainty is often subsequently ignored. In this article we review more than 40 threshold selection procedures, including semiparametric methods based on Hill's estimator, visual diagnostics, goodness-of-fit tests, and others based on extended generalized Pareto models. Starting with the…

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Semiparametric Off-Policy Inference for Optimal Policy Values under Possible Non-Uniqueness

最优策略可能不唯一时的半参数离策略价值推断

Off-policy evaluation (OPE) constructs confidence intervals for the value of a target policy using data generated under a different behavior policy. Most existing inference methods focus on fixed target policies and may fail when the target policy is estimated as optimal, particularly when the optimal policy is non-unique or nearly deterministic. We study inference for the value of optimal policies in Markov decision processes. In an auxiliary augmented transition-sampling…

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Causal Inference with the Napkin Graph

Napkin 因果图下的因果推断

Unmeasured confounding can render identification strategies based on adjustment functionals invalid. We study the "Napkin" graph, a causal structure that encapsulates features of M-bias, instrumental variables, and classical back-door and front-door settings, yet identifies the average treatment effect through a nonstandard ratio of two g-formulas. We develop influence-function-based estimators for this functional, including doubly-robust one-step and targeted minimum…

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Higher-Order Debiased Estimators for General Treatment Models

一般处理模型中的高阶去偏估计器

It is now well known that estimators based on influence functions can be sub-optimal in terms of convergence rates in various settings. To address this issue, higher-order influence functions (HOIF) are developed, generalizing the classical semiparametric theory. However, most existing results in this regard focus on treatment effect parameters defined in explicit forms, such as average treatment effects (ATE). In applications, economists are often confronted with tasks of…

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Transporting causal effects from a randomized trial without "transportability:" a case study of political advertising during U.S. elections

放宽可迁移性假设的随机试验效应外推:美国选举政治广告案例

During the 2020 U.S. presidential election, Aggarwal et al. (2023) conducted a large-scale randomized experiment to evaluate a digital ad campaign against Trump in five battleground states. While the study found no effect on voter turnout, it's unclear whether this null result generalizes to other battleground states, notably Georgia, which played a unique role in the 2020 election and differs from the battleground states. Inspired by the study, we present a transfer…

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Causal Inference with a Hidden Treatment

真实处理不可观测时的因果推断

In many causal inference settings, the treatment of interest is not directly observed; instead, one or more error-prone proxy measurements are available, creating a fundamental identification challenge. Building on identification methods for hidden treatments with proxies, we develop a general semiparametric framework for causal effect estimation that accommodates several common estimands. Hidden treatment models differ fundamentally from classical missing-data settings,…

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BayesFBHborrow: An R Package for Bayesian borrowing for time-to-event data from a flexible baseline hazard

BayesFBHborrow:基于灵活基线风险的生存数据贝叶斯信息借用 R 包

Statistical methods that leverage external trial information to help accelerate drug development are becoming increasingly popular. Bayesian methods facilitate dynamic borrowing, where the similarity of the response guides how much information is used. We have proposed a semiparametric Bayesian borrowing model for time-to-event data, with smoothing priors that allows the baseline hazard to take any form via an ensemble average. By accurately modelling the baseline hazard,…

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Privacy-preserving Meta-analysis through Low-Rank Basis Hunting

通过低秩基函数搜寻实现保护隐私的元分析

A central challenge of meta-analysis is that the populations underlying existing studies often differ from the target population in unknown ways. We study the problem of predicting function-valued quantities, such as regression and conditional average treatment effect functions, for a new target population using only study-level covariates and study-specific function estimates. We propose MetaHunt, a new meta-analysis methodology based on a shared low-rank structure, in…

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Semi- and non-parametric approaches to individualized treatment regimes in the presence of causal mediation

存在因果中介时个体化治疗规则的半参数与非参数方法

Individualized treatment rules (ITRs) map an individual patient's characteristics to their recommended treatment value. Typically, the optimal ITR is defined as the rule which maximizes a mean counterfactual outcome; the resulting ITR maximizes the effect of treatment along all causal pathways to the outcome, including indirect pathways through mediating variables. Although maximizing the total effect is often sufficient, explicitly incorporating causal mediation in an ITR…

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Exploiting independence constraints for efficient estimation of bounds on causal effects in the presence of unmeasured confounding

利用独立性约束高效估计未测混杂下的因果效应界

Causal graphs may inform covariate adjustment for estimating causal effects and improve estimation efficiency by exploiting the graphical structure. In many applications, however, the target causal parameter may not be point-identified due to the presence of unmeasured confounding. Sensitivity analysis methods address this challenge by characterizing bounds on the causal parameter under varying assumptions about the magnitude or form of unmeasured confounding. We focus on…

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