NP-LEAP: Nonparametric Latent Exchangeability Prior for Model-Lean Borrowing from Historical Data
NP-LEAP:借用历史数据的非参数潜在可交换性先验
Bayesian dynamic borrowing (BDB) methods leverage historical data to reduce treatment effect uncertainty, yet existing approaches rely on parametric outcome models susceptible to misspecification. We propose the nonparametric latent exchangeability prior (NP-LEAP), an outcome-agnostic, assumption-lean framework to borrow information from historical data. The NP-LEAP performs individual-level exchangeability assessment, inducing Bayesian model averaging over all possible…