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Median Optimal Treatment Regimes

中位数最优处理规则

Optimal treatment regimes are personalized policies for making a treatment decision based on subject characteristics, with the policy chosen to maximize some value. It is common to aim to maximize the mean outcome in the population, via a regime assigning treatment only to those whose mean outcome is higher under treatment versus control. However, the mean can be an unstable measure of centrality, resulting in imprecise statistical procedures, as well as unrobust decisions…

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Estimation of Tempered Stable Lévy Models of Infinite Variation

无限变差温和稳定 Lévy 模型的估计

We propose a new method for the estimation of a semiparametric tempered stable Lévy model. The estimation procedure combines iteratively an approximate semiparametric method of moment estimator, Truncated Realized Quadratic Variations (TRQV), and a newly found small-time high-order approximation for the optimal threshold of the TRQV of tempered stable processes. The method is tested via simulations to estimate the volatility and the Blumenthal-Getoor index of the generalized…

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Intervention treatment distributions that depend on the observed treatment process and model double robustness in causal survival analysis

依赖观测处理过程的干预分布与因果生存分析中的模型双重稳健性

The generalized g-formula can be used to estimate the probability of survival under a sustained treatment strategy. When treatment strategies are deterministic, estimators derived from the so-called efficient influence function (EIF) for the g-formula will be doubly robust to model misspecification. In recent years, several practical applications have motivated estimation of the g-formula under non-deterministic treatment strategies where treatment assignment at each time…

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Heterogeneous Treatment Effect Estimation based on a Partially Linear Nonparametric Bayes Model

基于部分线性非参数贝叶斯模型的异质性处理效应估计

Recently, conditional average treatment effect (CATE) estimation has been attracting much attention due to its importance in various fields such as statistics, social and biomedical sciences. This study proposes a partially linear nonparametric Bayes model for the heterogeneous treatment effect estimation. A partially linear model is a semiparametric model that consists of linear and nonparametric components in an additive form. A nonparametric Bayes model that uses a…

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Assessing Time-Varying Causal Effect Moderation in the Presence of Cluster-Level Treatment Effect Heterogeneity

群组层面处理效应异质性下的时变因果效应调节评估

The micro-randomized trial (MRT) is a sequential randomized experimental design to empirically evaluate the effectiveness of mobile health (mHealth) intervention components that may be delivered at hundreds or thousands of decision points. MRTs have motivated a new class of causal estimands, termed "causal excursion effects", for which semiparametric inference can be conducted via a weighted, centered least squares criterion (Boruvka et al., 2018). Existing methods assume…

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Efficient counterfactual estimation in semiparametric discrete choice models: a note on Chiong, Hsieh, and Shum (2017)

半参数离散选择模型的高效反事实估计:一则方法补充

I suggest an enhancement of the procedure of Chiong, Hsieh, and Shum (2017) for calculating bounds on counterfactual demand in semiparametric discrete choice models. Their algorithm relies on a system of inequalities indexed by cycles of a large number $M$ of observed markets and hence seems to require computationally infeasible enumeration of all such cycles. I show that such enumeration is unnecessary because solving the "fully efficient" inequality system exploiting…

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Demystifying statistical learning based on efficient influence functions

理解基于有效影响函数的统计学习

Evaluation of treatment effects and more general estimands is typically achieved via parametric modelling, which is unsatisfactory since model misspecification is likely. Data-adaptive model building (e.g. statistical/machine learning) is commonly employed to reduce the risk of misspecification. Naive use of such methods, however, delivers estimators whose bias may shrink too slowly with sample size for inferential methods to perform well, including those based on the…

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Selective Inference in Propensity Score Analysis

倾向得分分析中的选择后推断

Selective inference (post-selection inference) is a methodology that has attracted much attention in recent years in the fields of statistics and machine learning. Naive inference based on data that are also used for model selection tends to show an overestimation, and so the selective inference conditions the event that the model was selected. In this paper, we develop selective inference in propensity score analysis with a semiparametric approach, which has become a…

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Periodic Variable Stars Modulated by Time-Varying Parameters

时变参数调制的周期变星模型

Many astrophysical phenomena are time-varying, in the sense that their brightness change over time. In the case of periodic stars, previous approaches assumed that changes in period, amplitude, and phase are well described by either parametric or piecewise-constant functions. With this paper, we introduce a new mathematical model for the description of the so-called modulated light curves, as found in periodic variable stars that exhibit smoothly time-varying parameters such…

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Nonparametric Scanning For Nonrandom Missing Data With Continuous Instrumental Variables

利用连续工具变量对非随机缺失数据进行非参数扫描

This article introduces a new instrumental variable approach for estimating unknown population parameters with data having nonrandom missing values. With coarse and discrete instruments, Shao and Wang (2016) proposed a semiparametric method that uses the added information to identify the tilting parameter from the missing data propensity model. A naive application of this idea to continuous instruments through arbitrary discretizations is apt to be inefficient, and maybe…

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Generalized Kernel Ridge Regression for Causal Inference with Missing-at-Random Sample Selection

随机缺失样本选择下用于因果推断的广义核岭回归

I propose kernel ridge regression estimators for nonparametric dose response curves and semiparametric treatment effects in the setting where an analyst has access to a selected sample rather than a random sample; only for select observations, the outcome is observed. I assume selection is as good as random conditional on treatment and a sufficiently rich set of observed covariates, where the covariates are allowed to cause treatment or be caused by treatment -- an extension…

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Causal Mediation and Sensitivity Analysis for Mixed-Scale Data

混合尺度数据的因果中介与敏感性分析

The goal of causal mediation analysis, often described within the potential outcomes framework, is to decompose the effect of an exposure on an outcome of interest along different causal pathways. Using the assumption of sequential ignorability to attain non-parametric identification, Imai et al. (2010) proposed a flexible approach to measuring mediation effects, focusing on parametric and semiparametric normal/Bernoulli models for the outcome and mediator. Less attention…

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A framework for causal segmentation analysis with machine learning in large-scale digital experiments

大型数字实验中基于机器学习的因果分群分析框架

We present an end-to-end methodological framework for causal segment discovery that aims to uncover differential impacts of treatments across subgroups of users in large-scale digital experiments. Building on recent developments in causal inference and non/semi-parametric statistics, our approach unifies two objectives: (1) the discovery of user segments that stand to benefit from a candidate treatment based on subgroup-specific treatment effects, and (2) the evaluation of…

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The Balancing Act in Causal Inference

因果推断中的协变量平衡

The idea of covariate balance is at the core of causal inference. Inverse propensity weights play a central role because they are the unique set of weights that balance the covariate distributions of different treatment groups. We discuss two broad approaches to estimating these weights: the more traditional one, which fits a propensity score model and then uses the reciprocal of the estimated propensity score to construct weights, and the balancing approach, which estimates…

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Performance and Application of Estimators for the Value of an Optimal Dynamic Treatment Rule

最优动态治疗规则价值估计量的表现与应用

Given an (optimal) dynamic treatment rule, it may be of interest to evaluate that rule -- that is, to ask the causal question: what is the expected outcome had every subject received treatment according to that rule? In this paper, we study the performance of estimators that approximate the true value of: 1) an $a$ $priori$ known dynamic treatment rule 2) the true, unknown optimal dynamic treatment rule (ODTR); 3) an estimated ODTR, a so-called "data-adaptive parameter,"…

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Bayesian Analysis of Stochastic Volatility Model using Finite Gaussian Mixtures with Unknown Number of Components

使用成分数未知的有限高斯混合进行随机波动模型的贝叶斯分析

Financial studies require volatility based models which provides useful insights on risks related to investments. Stochastic volatility models are one of the most popular approaches to model volatility in such studies. The asset returns under study may come in multiple clusters which are not captured well assuming standard distributions. Mixture distributions are more appropriate in such situations. In this work, an algorithm is demonstrated which is capable of studying…

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Efficient and Robust Semi-supervised Estimation of ATE with Partially Annotated Treatment and Response

处理与结果仅部分标注时平均处理效应的高效稳健半监督估计

A notable challenge of leveraging Electronic Health Records (EHR) for treatment effect assessment is the lack of precise information on important clinical variables, including the treatment received and the response. Both treatment information and response often cannot be accurately captured by readily available EHR features and require labor intensive manual chart review to precisely annotate, which limits the number of available gold standard labels on these key variables.…

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Semi-parametric estimation of the EASI model: Welfare implications of taxes identifying clusters due to unobserved preference heterogeneity

EASI 模型的半参数估计:偏好异质性聚类与税收福利效应

We provide a novel inferential framework to estimate the exact affine Stone index (EASI) model, and analyze welfare implications due to price changes caused by taxes. Our inferential framework is based on a non-parametric specification of the stochastic errors in the EASI incomplete demand system using Dirichlet processes. Our proposal enables to identify consumer clusters due to unobserved preference heterogeneity taking into account, censoring, simultaneous endogeneity and…

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Variance Reduction for Causal Inference

因果推断中的方差降低

Propensity score methods have been shown to be powerful in obtaining efficient estimators of average treatment effect (ATE) from observational data, especially under the existence of confounding factors. When estimating, deciding which type of covariates need to be included in the propensity score function is important, since incorporating some unnecessary covariates may amplify both bias and variance of estimators of ATE. In this paper, we show that including additional…

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Fully Modified Least Squares Cointegrating Parameter Estimation in Multicointegrated Systems

多重协整系统中的完全修正最小二乘协整参数估计

Multicointegration is traditionally defined as a particular long run relationship among variables in a parametric vector autoregressive model that introduces additional cointegrating links between these variables and partial sums of the equilibrium errors. This paper departs from the parametric model, using a semiparametric formulation that reveals the explicit role that singularity of the long run conditional covariance matrix plays in determining multicointegration. The…

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Optimal Covariate Balancing Conditions in Propensity Score Estimation

倾向得分估计中的最优协变量平衡条件

Inverse probability of treatment weighting (IPTW) is a popular method for estimating the average treatment effect (ATE). However, empirical studies show that the IPTW estimators can be sensitive to the misspecification of the propensity score model. To address this problem, researchers have proposed to estimate propensity score by directly optimizing the balance of pre-treatment covariates. While these methods appear to empirically perform well, little is known about how the…

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The Influence Function of Semiparametric Estimators

半参数估计量的影响函数

Many useful parameters depend on nonparametric first steps. Examples include games, dynamic discrete choice, average exact consumer surplus, and treatment effects. Often estimators of these parameters are asymptotically equivalent to a sample average of an object referred to as the influence function. The influence function is useful in local policy analysis, in evaluating local sensitivity of estimators, constructing debiased machine learning estimators, in efficiency…

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Generalized Covariance Estimator

广义协方差估计量

We consider a class of semi-parametric dynamic models with strong white noise errors. This class of processes includes the standard Vector Autoregressive (VAR) model, the nonfundamental structural VAR, the mixed causal-noncausal models, as well as nonlinear dynamic models such as the (multivariate) ARCH-M model. For estimation of processes in this class, we propose the Generalized Covariance (GCov) estimator, which is obtained by minimizing a residual-based multivariate…

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Designing efficient randomized trials: power and sample size calculation when using semiparametric efficient estimators

高效随机试验设计:使用半参数有效估计量时的功效与样本量计算

Trials enroll a large number of subjects in order to attain power, making them expensive and time-consuming. Sample size calculations are often performed with the assumption of an unadjusted analysis, even if the trial analysis plan specifies a more efficient estimator (e.g. ANCOVA). This leads to conservative estimates of required sample sizes and an opportunity for savings. Here we show that a relatively simple formula can be used to estimate the power of any two-arm,…

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