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半参数与效率:半参数模型、有效估计与效率界。
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Rate doubly robust estimation for weighted average treatment effects

加权平均处理效应的速率双重稳健估计

The weighted average treatment effect (WATE) defines a versatile class of causal estimands for populations characterized by propensity score weights, including the average treatment effect (ATE), treatment effect on the treated (ATT), on controls (ATC), and for the overlap population (ATO). WATE has broad applicability in social and medical research, as many datasets from these fields align with its framework. However, the literature lacks a systematic investigation into the…

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Semiparametric principal stratification analysis beyond monotonicity

超越单调性假设的半参数主分层分析

Intercurrent events, common in clinical trials and observational studies, affect the existence or interpretation of final outcomes. Principal stratification addresses this challenge by defining local average treatment effect estimands within subpopulations, but often relies on restrictive assumptions such as monotonicity and counterfactual intermediate independence. To overcome these limitations, we propose a semiparametric framework for principal stratification analysis…

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A Review of Statistical Methods for Handling Nonignorable Missing Data using Instrument Approach

利用工具变量处理不可忽略缺失数据的统计方法综述

Nonignorable missing data, where the probability of missingness depends on unobserved values, presents a significant challenge in statistical analysis. Traditional methods often rely on strong parametric assumptions that are difficult to verify and may lead to biased estimates if misspecified. Recent advances have introduced the concept of a nonresponse instrument or shadow variable as a powerful tool to enhance model identifiability without requiring full parametric…

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Canonical correlation analysis of stochastic trends via functional approximation

通过函数逼近对随机趋势进行典型相关分析

This paper proposes a novel approach for semiparametric inference on the number $s$ of common trends and their loading matrix $ψ$ in $I(1)/I(0)$ systems. It combines functional approximation of limits of random walks and canonical correlations analysis, performed between the $p$ observed time series of length $T$ and the first $K$ discretized elements of an $L^2$ basis. Tests and selection criteria on $s$, and estimators and tests on $ψ$ are proposed; their properties are…

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Time-Varying Heterogeneous Treatment Effects in Event Studies

事件研究中的时变异质性处理效应

This paper examines the identification and estimation of heterogeneous treatment effects in event studies, emphasizing the importance of both lagged dependent variables and treatment effect heterogeneity. We show that omitting lagged dependent variables can induce omitted variable bias in the estimated time-varying treatment effects. We develop a novel semiparametric approach based on a short-T dynamic linear panel model with correlated random coefficients, where the…

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Identification and estimation of mediational effects of longitudinal modified treatment policies

纵向修正处理政策的中介效应识别与估计

We demonstrate a comprehensive semiparametric approach to causal mediation analysis, addressing the complexities inherent in settings with longitudinal and continuous treatments, confounders, and mediators. Our methodology utilizes a nonparametric structural equation model and a cross-fitted sequential regression technique based on doubly robust pseudo-outcomes, yielding an efficient, asymptotically normal estimator without relying on restrictive parametric modeling…

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Semiparametric Triple Difference Estimators

半参数三重差分估计量

The triple difference causal inference framework is an extension of the well-known difference-in-differences framework. It relaxes the parallel trends assumption of the difference-in-differences framework through leveraging data from an auxiliary domain. Despite being commonly applied in empirical research, the triple difference framework has received relatively limited attention in the statistics literature. Specifically, investigating the intricacies of identification and…

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Two-Stage Least Squares Instrumental Variable Estimation for Semiparametric Accelerated Failure Time Models with Right-Censored Data

右删失数据下半参数加速失效时间模型的两阶段最小二乘工具变量估计

Instrumental variable (IV) analysis is widely used in fields such as economics and epidemiology to address unobserved confounding and measurement error when estimating the causal effects of intermediate covariates on outcomes. However, extending the commonly used two-stage least squares (TSLS) approach to survival settings is nontrivial due to censoring. This paper introduces a novel extension of TSLS to the semiparametric accelerated failure time (AFT) model with…

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Semiparametric sensitivity analysis: unmeasured confounding in observational studies

半参数敏感性分析:观察性研究中的未测量混杂

Establishing cause-effect relationships from observational data often relies on untestable assumptions. It is crucial to know whether, and to what extent, the conclusions drawn from non-experimental studies are robust to potential unmeasured confounding. In this paper, we focus on the average causal effect (ACE) as our target of inference. We generalize the sensitivity analysis approach developed by Robins et al. (2000), Franks et al. (2020), and Zhou and Yao (2023). We use…

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Average Causal Effect Estimation in DAGs with Hidden Variables: Beyond Back-Door and Front-Door Criteria

隐变量 DAG 中的平均因果效应估计:超越后门与前门准则

The identification theory for causal effects in directed acyclic graphs (DAGs) with hidden variables is well established, but methods for estimating and inferring functionals that extend beyond the g-formula remain underdeveloped. Previous studies have introduced semiparametric estimators for such functionals in a broad class of DAGs with hidden variables. While these estimators exhibit desirable statistical properties such as double robustness in certain cases, they also…

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Improving the Estimation of Lifetime Effects in A/B Testing via Treatment Locality

利用处理局部性改进 A/B 测试中的终身效应估计

Utilizing randomized experiments to evaluate the effect of short-term treatments on the short-term outcomes has been well understood and become the golden standard in industrial practice. However, as service systems become increasingly dynamical and personalized, much focus is shifting toward maximizing long-term outcomes, such as customer lifetime value, through lifetime exposure to interventions. Our goal is to assess the impact of treatment and control policies on…

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Nonparametric estimation of the Patient Weighted While-Alive Estimand

患者加权存活期间估计目标的非参数估计

In clinical trials with recurrent events, such as repeated hospitalizations terminating with death, it is important to consider the patient events overall history for a thorough assessment of treatment effects. The occurrence of fewer events due to early deaths can lead to misinterpretation, emphasizing the importance of a while-alive strategy as suggested in Schmidli et al. (2023). In this study, we focus on the patient weighted while-alive estimand, represented as the…

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Causal Spatial Quantile Regression

因果空间分位数回归

Treatment effects in a wide range of economic, environmental, and epidemiological applications often vary across space, and understanding the heterogeneity of causal effects across space and outcome quantiles is a critical challenge in spatial causal inference. To effectively capture spatial heterogeneity in distributional treatment effects, we propose a novel semiparametric neural network-based causal framework leveraging deep spatial quantile regression and then construct…

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Semiparametric model averaging for high-dimensional quantile regression with nonignorable nonresponse

不可忽略缺失下高维分位数回归的半参数模型平均

Model averaging has demonstrated superior performance for ensemble forecasting in high-dimensional framework, its extension to incomplete datasets remains a critical but underexplored challenge. Moreover, identifying the parsimonious model through averaging procedure in quantile regression demands urgent methodological innovation. In this paper, we propose a novel model averaging method for high-dimensional quantile regression with nonignorable missingness. The idea is to…

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Doubly robust estimation and sensitivity analysis with outcomes truncated by death in multi-arm clinical trials

多组临床试验中死亡截断结局的双重稳健估计与敏感性分析

In clinical trials, the observation of participant outcomes may frequently be hindered by death, leading to ambiguity in defining a scientifically meaningful final outcome for those who die. Principal stratification methods are valuable tools for addressing the average causal effect among always-survivors, i.e., the average treatment effect among a subpopulation defined as those who would survive regardless of treatment assignment. Although robust methods for the…

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Nonlinear Impulse Response Functions and Local Projections

非线性脉冲响应函数与局部投影

The goal of this paper is to extend the nonparametric estimation of Impulse Response Functions (IRF) by means of local projections in the nonlinear dynamic framework. We discuss the existence of a nonlinear autoregressive representation for Markov processes and explain how their IRFs are directly linked to the Nonlinear Local Projection (NLP), as in the case for the linear setting. We present a fully nonparametric LP estimator in the one dimensional nonlinear framework,…

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Tensor-product interactions in Markov-switching models

马尔可夫转换模型中的张量积交互

Markov-switching models are a powerful tool for modelling time series data that are driven by underlying latent states. As such, they are widely used in behavioural ecology, where discrete states can serve as proxies for behavioural modes and enable inference on latent behaviour driving e.g. observed movement. To understand drivers of behavioural changes, it is common to link model parameters to covariates. Over the last decade, nonparametric approaches have gained traction…

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Factor Informed Double Deep Learning For Average Treatment Effect Estimation

用于平均处理效应估计的因子辅助双重深度学习

We investigate the problem of estimating the average treatment effect (ATE) under a very general setup where the covariates can be high-dimensional, highly correlated, and can have sparse nonlinear effects on the propensity and outcome models. We present the use of a Double Deep Learning strategy for estimation, which involves combining recently developed factor-augmented deep learning-based estimators, FAST-NN, for both the response functions and propensity scores to…

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On a Debiased and Semiparametric Efficient Changes-in-Changes Estimator

去偏且具有半参数效率的变化中变化估计量

We present a novel extension of the influential changes-in-changes (CiC) framework of Athey and Imbens (2006) for estimating the average treatment effect on the treated (ATT) and distributional causal effects in panel data with unmeasured confounding. While CiC relaxes the parallel trends assumption in difference-in-differences (DiD), existing methods typically assume a scalar unobserved confounder and monotonic outcome relationships, and lack inference tools that…

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Bayesian Double Machine Learning for Causal Inference

用于因果推断的贝叶斯双重机器学习

This paper proposes a simple, novel, and fully-Bayesian approach for causal inference in partially linear models with high-dimensional control variables. Off-the-shelf machine learning methods can introduce biases in the causal parameter known as regularization-induced confounding. To address this, we propose a Bayesian Double Machine Learning (BDML) method, which modifies a standard Bayesian multivariate regression model and recovers the causal effect of interest from the…

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Efficient Statistical Estimation for Sequential Adaptive Experiments with Implications for Adaptive Designs

序贯自适应实验的有效统计估计及其对自适应设计的启示

Adaptive experimental designs have gained popularity in clinical trials and online experiments. Unlike traditional, fixed experimental designs, adaptive designs can dynamically adjust treatment randomization probabilities and other design features in response to data accumulated sequentially during the experiment. These adaptations are useful to achieve diverse objectives, including reducing uncertainty in the estimation of causal estimands or increasing participants'…

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High-dimensional Longitudinal Inference via a De-sparsified Dantzig-Selector

高维纵向数据下基于去稀疏化 Dantzig 选择器的统计推断

In this paper, we consider statistical inference with generalized linear models in high dimensions under a longitudinal clustered data framework. Specifically, we propose a de-sparsified version of an initial Dantzig-type regularized estimator in regression settings and provide theoretical justification for both linear and generalized linear models. We present extensive numerical simulations demonstrating the effectiveness of our method for continuous and binary data. For…

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Causal Estimation and Inference in Nonlinear Mendelian Randomization Studies

非线性孟德尔随机化研究中的因果估计与推断

Mendelian randomization (MR) is widely used to uncover causal relationships in the presence of unmeasured confounders. However, most existing MR methods presuppose linear causality, risking bias when the true relationships are nonlinear, which is a common empirical scenario. In this paper, we compared two prevalent instrumental variable techniques (the two-stage prediction method and the control function method) under both linear and nonlinear settings, and addressed key…

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Minimax Semiparametric Learning With Approximate Sparsity

近似稀疏下的极小极大半参数学习

Estimating linear, mean-square continuous functionals is a pivotal challenge in statistics. In high-dimensional contexts, this estimation is often performed under the assumption of exact model sparsity, meaning that only a small number of parameters are precisely non-zero. This excludes models where linear formulations only approximate the underlying data distribution, such as nonparametric regression methods that use basis expansion such as splines, kernel methods or…

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