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Variable selection in frailty mixture cure models via penalized likelihood estimation

脆弱混合治愈模型中的惩罚似然变量选择

Variable selection naturally arises as a useful subject when faced with data with massive predictor space. In addition to the massive dimensionality, the data may be characterized by intra-subject correlation, and cure fraction, which are ubiquitous in longitudinal studies with recurrent events defining the endpoint of interest. However, variable selection methods simultaneously adjusting for intra-subject correlation, and cure fraction are rare. We propose a comprehensive…

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Inference in High-Dimensional Panel Models: Two-Way Dependence and Unobserved Heterogeneity

高维面板模型的推断:双向依赖与未观测异质性

Panel data allows for the modeling of unobserved heterogeneity, significantly raising the number of nuisance parameters and making high dimensionality a practical issue. Meanwhile, temporal and cross-sectional dependence in panel data further complicates high-dimensional estimation and inference. This paper proposes a toolkit for high-dimensional panel models with large cross-sectional and time sample sizes. To reduce the dimensionality, I propose a variant of LASSO for…

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Optimal Decision Rules when Payoffs are Partially Identified

收益部分识别时的最优决策规则

We derive asymptotically optimal statistical decision rules for discrete choice problems when payoffs depend on a partially-identified parameter $θ$ and the decision maker can use a point-identified parameter $μ$ to deduce restrictions on $θ$. Examples include treatment choice under partial identification and pricing with rich unobserved heterogeneity. Our notion of optimality combines a minimax approach to handle the ambiguity from partial identification of $θ$ given $μ$ wit…

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Semiparametric inference for impulse response functions using double/debiased machine learning

用双重/去偏机器学习对脉冲响应函数进行半参数推断

We introduce a double/debiased machine learning estimator for the impulse response function in settings where a time series of interest is subjected to multiple discrete treatments, assigned over time, which can have a causal effect on future outcomes. The proposed estimator can rely on fully nonparametric relations between treatment and outcome variables, opening up the possibility to use flexible machine learning approaches to estimate impulse response functions. To this…

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Undersmoothed LASSO Models for Propensity Score Weighting and Synthetic Negative Control Exposures for Bias Detection

倾向得分加权中的欠平滑LASSO与合成负对照暴露偏差检测

The propensity score (PS) is often used to control for large numbers of covariates in high-dimensional healthcare database studies. The least absolute shrinkage and selection operator (LASSO) has become the most widely used tool for fitting large-scale PS models in these settings. LASSO uses L1 regularized regression to prevent overfitting by shrinking coefficients toward zero (setting some exactly to zero). The degree of regularization is typically selected using…

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Testing Shape Restrictions with Continuous Treatment: A Transformation Model Approach

连续处理下的形状限制检验:变换模型方法

We propose tests for the convexity/linearity/concavity of a transformation of the dependent variable in a semiparametric transformation model. These tests can be used to verify monotonicity of the treatment effect, or, equivalently, concavity/convexity of the outcome with respect to the treatment, in (quasi-)experimental settings. Our procedure does not require estimation of the transformation or the distribution of the error terms. The statistic takes the form of a U…

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Assumption-Lean Post-Integrated Inference with Surrogate Control Outcomes

利用替代控制结果进行弱假设数据整合后推断

Data integration methods aim to extract low-dimensional embeddings from high-dimensional outcomes to remove unwanted variations, such as batch effects and unmeasured covariates, across heterogeneous datasets. However, multiple hypothesis testing after integration can be biased due to data-dependent processes. We introduce a robust post-integrated inference method that accounts for latent heterogeneity by utilizing control outcomes. Leveraging causal interpretations, we…

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Augmented match weighted estimators for average treatment effects

平均处理效应的增广匹配加权估计量

Propensity score matching (PSM) and augmented inverse propensity weighting (AIPW) are widely used in observational studies to estimate causal effects. The two approaches present complementary features. The AIPW estimator is doubly robust and locally efficient but can be unstable when the propensity scores are close to zero or one due to weighting by the inverse of the propensity score. On the other hand, PSM circumvents the instability of propensity score weighting but it…

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The causal effects of modified treatment policies under network interference

网络干扰下修正处理政策的因果效应

Modified treatment policies are a widely applicable class of interventions useful for studying the causal effects of continuous exposures. Approaches to evaluating their causal effects assume no interference, meaning that such effects cannot be learned from data in settings where the exposure of one unit affects the outcomes of others, as is common in spatial or network data. We introduce a new class of intervention, induced modified treatment policies, which we show…

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Marginal Interventional Effects

边际干预效应

Conventional causal estimands, such as the average treatment effect (ATE), capture how the mean outcome in a population or subpopulation would change if all units were assigned to treatment versus control. Real-world policy changes, however, are often incremental, changing treatment status for only a small segment of the population -- those at or near the "margin of participation." To formalize this idea, two parallel literatures in economics and in statistics and…

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Balancing Weights for Causal Mediation Analysis

因果中介分析的平衡权重

This paper develops methods for estimating the natural direct and indirect effects in causal mediation analysis. The efficient influence function-based estimator (EIF-based estimator) and the inverse probability weighting estimator (IPW estimator), which are standard in causal mediation analysis, both rely on the inverse of the estimated propensity scores, and thus they are vulnerable to two key issues (i) instability and (ii) finite-sample covariate imbalance. We propose…

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SLOACI: Surrogate-Leveraged Online Adaptive Causal Inference

SLOACI:利用替代结局的在线自适应因果推断

Adaptive experimental designs have gained increasing attention across a range of domains. In this paper, we propose a new methodological framework, surrogate-leveraged online adaptive causal inference (SLOACI), which integrates predictive surrogate outcomes into adaptive designs to enhance efficiency. For downstream analysis, we construct the adaptive augmented inverse probability weighting estimator for the average treatment effect using collected data. Our procedure…

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Estimation of Semiparametric Factor Models with Missing Data

缺失数据下半参数因子模型的估计

We study semiparametric factor models in high-dimensional panels where the factor loadings consist of a nonparametric component explained by observed covariates and an idiosyncratic component capturing unobserved heterogeneity. A key challenge in empirical applications is the presence of missing observations, which can distort both factor recovery and loading estimation. To address this issue, we develop a projected principal component analysis (PPCA) procedure that…

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Unobserved Heterogeneous Spillover Effects in Instrumental Variable Models

工具变量模型中不可观测的异质溢出效应

This paper develops a general framework for identifying causal effects in settings with spillovers, where both outcomes and endogenous treatment decisions are influenced by peers within a known group. It introduces the generalized local average controlled spillover and direct effects (LACSEs and LACDEs), which extend the local average treatment effect framework to settings with spillovers and establish sufficient conditions for their point identification without restricting…

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Auto-Doubly Robust Estimation of Causal Effects on a Network

网络因果效应的自回归双重稳健估计

This paper develops new methods for causal inference in observational studies on a single large network of interconnected units, addressing two key challenges: long-range dependence among units and the presence of general interference. We introduce a novel network version of Augmented Inverse Propensity Weighted, which combines propensity score and outcome models defined on the network to achieve doubly robust identification and estimation of both direct and spillover causal…

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Heterogeneity-Aware Federated Causal Inference Leveraging Effect-Measure Transportability

利用效应度量可迁移性的异质性感知联邦因果推断

Federated learning of causal estimands offers a powerful strategy to improve estimation efficiency by leveraging data from multiple study sites while preserving privacy. Existing literature has primarily focused on the average treatment effect using single data source, whereas our work addresses a broader class of causal measures across multiple sources. We derive and compare semiparametrically efficient estimators under two transportability assumptions, which impose…

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Bayesian Semiparametric Causal Inference: Targeted Doubly Robust Estimation of Treatment Effects

贝叶斯半参数因果推断:处理效应的目标化双重稳健估计

We propose a semiparametric Bayesian methodology for estimating the average treatment effect (ATE) within the potential outcomes framework using observational data with high-dimensional nuisance parameters. Our method introduces a Bayesian debiasing procedure that corrects for bias arising from nuisance estimation and employs a targeted modeling strategy based on summary statistics rather than the full data. These summary statistics are identified in a debiased manner,…

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Causal Inference on Sequential Treatments via Tensor Completion

通过张量补全推断序贯处理的因果效应

Marginal Structural Models (MSMs) are popular for causal inference of sequential treatments in longitudinal observational studies, which however are sensitive to model misspecification. To achieve flexible modeling, we envision the potential outcomes to form a three-dimensional tensor indexed by subject, time, and treatment regime and propose a tensorized history-restricted MSM (HRMSM). The semi-parametric tensor factor model allows us to leverage the underlying low-rank…

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Towards a Unified Theory for Semiparametric Data Fusion with Individual-Level Data

个体数据半参数融合的统一理论探索

We address the goal of conducting inference about a smooth finite-dimensional parameter by utilizing individual-level data from various independent sources. Recent advancements have led to the development of a comprehensive theory capable of handling scenarios where different data sources align with, possibly distinct subsets of, conditional distributions of a single factorization of the joint target distribution. While this theory proves effective in many significant…

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Double machine learning for causal inference in a multivariate sample selection model

多变量样本选择模型中的因果推断与双重机器学习

We propose plug-in (PI) and double machine learning (DML) estimators of average treatment effect (ATE), average treatment effect on the treated (ATET) and local average treatment effect (LATE) in the multivariate sample selection model with ordinal selection equations. Our DML estimators are doubly-robust and based on the efficient influence functions. Finite sample properties of the proposed estimators are studied and compared on simulated data. Specifically, the results of…

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Difference-in-Differences with Compositional Changes

存在样本构成变化时的双重差分

This paper studies Difference-in-Differences (DiD) setups with repeated cross-sectional data and potential compositional changes across time periods. We begin our analysis by deriving the efficient influence function and the semiparametric efficiency bound for the average treatment effect on the treated (ATT). We introduce nonparametric estimators that attain the semiparametric efficiency bound under mild rate conditions on the estimators of the nuisance functions,…

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Simple Estimation of Semiparametric Models with Measurement Errors

含测量误差半参数模型的简便估计

We develop a practical way of addressing the Errors-In-Variables (EIV) problem in the Generalized Method of Moments (GMM) framework. We focus on the settings in which the variability of the EIV is a fraction of that of the mismeasured variables, which is typical for empirical applications. For any initial set of moment conditions our approach provides a ``corrected'' set of moment conditions that are robust to the EIV. We show that the GMM estimator based on these moments is…

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Correcting sample selection bias with categorical outcomes

分类结果的样本选择偏差校正

In this paper, I propose a method for correcting sample selection bias when the outcome of interest is categorical, such as occupational choice, health status, or field of study. Classical approaches to sample selection rely on strong parametric distributional assumptions, which may be restrictive in practice. I develop a local representation that decomposes each joint probability into marginal probabilities and a category-specific association parameter that captures how…

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Rates of Convergence of Maximum Smoothed Log-Likelihood Estimators for Semi-Parametric Multivariate Mixtures

半参数多元混合模型的最大平滑对数似然估计量的收敛速率

Theoretical guarantees are established for a standard estimator in a semi-parametric finite mixture model, where each component density is modeled as a product of univariate densities under a conditional independence assumption. The focus is on the estimator that maximizes a smoothed log-likelihood function, which can be efficiently computed using a majorization-minimization algorithm. This smoothed likelihood applies a nonlinear regularization operator defined as the…

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