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正则化与变量选择:Lasso、惩罚估计、稀疏模型与变量选择。
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Proportional asymptotics of piecewise exponential proportional hazards models

分段指数比例风险模型的比例渐近理论

We study the flexible piecewise exponential model in a high dimensional setting where the number of covariates $p$ grows proportionally to the number of observations $n$ and under the hypothesis of random uncorrelated Gaussian designs. We prove rigorously that the optimal ridge penalized log-likelihood of the model converges in probability to the saddle point of a surrogate objective function. The technique of proof is the Convex Gaussian Min-Max theorem of Thrampoulidis,…

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Recent advances in doubly-robust weighted ordinary least squares techniques for dynamic treatment regime estimation

动态治疗方案估计中双稳健加权最小二乘技术的最新进展

A dynamic treatment regime (DTR) is an approach to delivering precision medicine that uses patient characteristics to guide treatment decisions for optimal health outcomes. Numerous methods have been proposed for DTR estimation, including dynamic weighted ordinary least squares (dWOLS), a regression-based approach that affords double robustness to model misspecification within an easy to implement analytical framework. Initially, the dWOLS approach was developed under the…

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Bayesian Variable Selection in Distributed Lag Models: A Focus on Binary Quantile and Count Data Regressions

分布滞后模型的贝叶斯变量选择:二元分位数与计数回归

Distributed Lag Models (DLMs) and similar regression approaches such as MIDAS have been used for many decades in econometrics and more recently to investigate how poor air quality adversely affects human health. In this paper we describe how to expand the utility of these models for Bayesian inference by leveraging latent variables. In particular we explain how to perform binary regression to better handle imbalanced data, how to incorporate negative binomial regression, and…

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Fundamental Computational Limits in Pursuing Invariant Causal Prediction and Invariance-Guided Regularization

不变因果预测与不变性引导正则化的基本计算极限

Pursuing invariant prediction from heterogeneous environments opens the door to learning causality in a purely data-driven way and has several applications in causal discovery and robust transfer learning. However, existing methods such as ICP [Peters et al., 2016] and EILLS [Fan et al., 2024] that can attain sample-efficient estimation are based on exponential time algorithms. In this paper, we show that such a problem is intrinsically hard in computation: the decision…

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Consistent support recovery for high-dimensional diffusions

高维扩散过程的一致支撑恢复

Statistical inference for stochastic processes has advanced significantly due to applications in diverse fields, but challenges remain in high-dimensional settings where parameters are allowed to grow with the sample size. This paper analyzes a d-dimensional ergodic diffusion process under sparsity constraints, focusing on the adaptive Lasso estimator, which improves variable selection and bias over the standard Lasso. We derive conditions under which the adaptive Lasso…

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Beyond Fixed Restriction Time: Adaptive Restricted Mean Survival Time Methods in Clinical Trials

超越固定截断时间:临床试验中的自适应限制平均生存时间方法

Restricted mean survival time (RMST) offers a compelling nonparametric alternative to hazard ratios for right-censored time-to-event data, particularly when the proportional hazards assumption is violated. By capturing the total event-free time over a specified horizon, RMST provides an intuitive and clinically meaningful measure of absolute treatment benefit. Nonetheless, selecting the restriction time $L$ poses challenges: choosing a small $L$ can overlook late-emerging…

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Cardinality-Regularized Hawkes-Granger Model

基数正则化的 Hawkes–Granger 模型

We propose a new sparse Granger-causal learning framework for temporal event data. We focus on a specific class of point processes called the Hawkes process. We begin by pointing out that most of the existing sparse causal learning algorithms for the Hawkes process suffer from a singularity in maximum likelihood estimation. As a result, their sparse solutions can appear only as numerical artifacts. In this paper, we propose a mathematically well-defined sparse causal…

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Generalized Reduced-Rank Regression with Homogeneity Pursuit

广义降秩回归中的同质性追踪

Homogeneity, low rank, and sparsity are three widely adopted assumptions in multi-response regression models to address the curse of dimensionality and improve estimation accuracy. However, there is limited literature that examines these assumptions within a unified framework. In this paper, we investigate the homogeneity, low rank, and sparsity assumptions under the generalized linear model with high-dimensional responses and covariates, encompassing a wide range of…

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The typicality principle and its implications for statistics and data science

典型性原则及其对统计学与数据科学的启示

A central focus of data science is the transformation of empirical evidence into knowledge. As such, the key insights and scientific attitudes of deep thinkers like Fisher, Popper, and Tukey are expected to inspire exciting new advances in machine learning and artificial intelligence in years to come. Along these lines, the present paper advances a novel {\em typicality principle} which states, roughly, that if the observed data is sufficiently ``atypical'' in a certain…

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Quantitative Theory of Money or Prices? A Historical, Theoretical, and Econometric Analysis

货币数量论还是价格数量论?历史、理论与计量分析

This research studies the relation between money and prices and its practical implications analyzing quarterly data from United States (1959-2022), Canada (1961-2022), United Kingdom (1986-2022), and Brazil (1996-2022). The historical, logical, and econometric consistency of the logical core of the two main theories of money is analyzed using objective bayesian and frequentist machine learning models, bayesian regularized artificial neural networks, and ensemble learning. It…

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Signal-to-noise ratio aware minimax analysis of sparse linear regression

稀疏线性回归的信噪比感知极小极大分析

We consider parameter estimation under sparse linear regression -- an extensively studied problem in high-dimensional statistics and compressed sensing. While the minimax framework has been one of the most fundamental approaches for studying statistical optimality in this problem, we identify two important issues that the existing minimax analyses face: (i) The signal-to-noise ratio appears to have no effect on the minimax optimality, while it shows a major impact in…

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Robust Bayesian graphical modeling using $γ$-divergence

基于γ散度的稳健贝叶斯图模型

Gaussian graphical model is one of the powerful tools to analyze conditional independence between two variables for multivariate Gaussian-distributed observations. When the dimension of data is moderate or high, penalized likelihood methods such as the graphical lasso are useful to detect significant conditional independence structures. However, the estimates are affected by outliers due to the Gaussian assumption. This paper proposes a novel robust posterior distribution…

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Sparse factor models of high dimension

高维稀疏因子模型

We consider the estimation of a sparse factor model where the factor loading matrix is assumed sparse. The estimation problem is reformulated as a penalized M-estimation criterion, while the restrictions for identifying the factor loading matrix accommodate a wide range of sparsity patterns. We prove the sparsistency property of the penalized estimator when the number of parameters is diverging, that is the consistency of the estimator and the recovery of the true zeros…

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Sparsity meets correlation in Gaussian sequence model

高斯序列模型中的稀疏性与相关性

We study estimation of an $s$-sparse signal in the $p$-dimensional Gaussian sequence model with equicorrelated observations and derive the minimax rate. A new phenomenon emerges from correlation, namely the rate scales with respect to $p-2s$ and exhibits a phase transition at $p-2s \asymp \sqrt{p}$. Correlation is shown to be a blessing provided it is sufficiently strong, and the critical correlation level exhibits a delicate dependence on the sparsity level. Due to…

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Envelope-Guided Regularization for Improved Prediction in High-Dimensional Multivariate Regression

包络引导正则化:高维多元回归预测改进

Envelope methods perform dimension reduction of predictors or responses in multivariate regression, exploiting the relationship between them to improve estimation efficiency. While most research on envelopes has focused on their estimation properties, certain envelope estimators have been shown to excel at prediction in both low and high dimensions. In this paper, we propose to further improve prediction through envelope-guided regularization (EgReg), a novel method which…

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Estimating Heterogeneous Causal Effects of High-Dimensional Treatments: Application to Conjoint Analysis

高维处理的异质性因果效应估计:联合分析应用

Estimation of heterogeneous treatment effects is an active area of research. Most of the existing methods, however, focus on estimating the conditional average treatment effects of a single, binary treatment given a set of pre-treatment covariates. In this paper, we propose a method to estimate the heterogeneous causal effects of high-dimensional treatments, which poses unique challenges in terms of estimation and interpretation. The proposed approach finds maximally…

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Penalized G-estimation for effect modifier selection in a structural nested mean model for repeated outcomes

重复结果结构嵌套均值模型中效应修饰变量选择的惩罚 G 估计

Effect modification occurs when the impact of the treatment on an outcome varies based on the levels of other covariates known as effect modifiers. Modeling these effect differences is important for etiological goals and for purposes of optimizing treatment. Structural nested mean models (SNMMs) are useful causal models for estimating the potentially heterogeneous effect of a time-varying exposure on the mean of an outcome in the presence of time-varying confounding. A…

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Penalized generalized linear mixed models for longitudinal outcomes in genetic association studies

遗传关联研究中纵向结果的惩罚广义线性混合模型

This work is motivated by analyses of longitudinal data collected from participants in the Quebec Longitudinal Study of Child Development (QLSCD) and the Quebec Newborn Twin Study (QNTS) to identify important genetic predictors for emotional and behavioral difficulties in childhood and adolescence. We propose a lasso penalized mixed model for continuous and binary longitudinal traits that allows the inclusion of multiple random effects to account for random individual…

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An Online Algorithm for Bayesian Variable Selection in Logistic Regression Models With Streaming Data

流式数据下逻辑回归贝叶斯变量选择的在线算法

In several modern applications, data are generated continuously over time, such as data generated from smartwatches. We assume data are collected and analyzed sequentially, in batches. Since traditional or offline methods can be extremely slow, Ghosh et al. (2025) proposed an online method for Bayesian model averaging (BMA). Inspired by the literature on renewable estimation, they developed an online Bayesian method for generalized linear models (GLMs) that reduces storage…

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Reconstructing East Asian Temperatures from 1368 to 1911 Using Historical Documents, Climate Models, and Data Assimilation

结合历史文献、气候模型与数据同化重建1368—1911年东亚气温

We propose a novel approach for reconstructing annual temperatures in East Asia from 1368 to 1911, leveraging the Reconstructed East Asian Climate Historical Encoded Series (REACHES). The lack of instrumental data during this period poses significant challenges to understanding past climate conditions. REACHES digitizes historical documents from the Ming and Qing dynasties of China, converting qualitative descriptions into a four-level ordinal temperature scale. However,…

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Recovering latent linkage structures and spillover effects with structural breaks in panel data models

面板模型结构突变下潜在联系结构与溢出效应的恢复

This paper introduces a framework to analyze time-varying spillover effects in panel data. We consider panel models where a unit's outcome depends not only on its own characteristics (private effects) but also on the characteristics of other units (spillover effects). The linkage of units is allowed to be latent and may shift at an unknown breakpoint. We propose a novel procedure to estimate the breakpoint, linkage structure, spillover and private effects. We address the…

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Supervised Kernel Thinning

监督式核稀疏化:加速核回归的压缩方法

The kernel thinning algorithm of Dwivedi & Mackey (2024) provides a better-than-i.i.d. compression of a generic set of points. By generating high-fidelity coresets of size significantly smaller than the input points, KT is known to speed up unsupervised tasks like Monte Carlo integration, uncertainty quantification, and non-parametric hypothesis testing, with minimal loss in statistical accuracy. In this work, we generalize the KT algorithm to speed up supervised learning…

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Functional Linear Cox Regression Model with Frailty

带脆弱性的函数型线性Cox回归模型

This paper presents a functional linear Cox regression model with frailty to tackle unobserved heterogeneity in survival data with functional covariates. While traditional Cox models are common, they struggle to incorporate frailty effects that represent individual differences not captured by observed covariates. Our model combines scalar and functional covariates with a frailty term to address these unmeasured influences, creating a robust framework for high-dimensional…

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A comparative study of augmented inverse propensity weighted estimators using outcome-oriented covariate selection via penalization with outcome-adaptive lasso

结合结局自适应 Lasso 的增广逆概率加权估计量比较

When estimating causal effects from observational data with numerous covariates, employing penalized covariate selection can improve the estimation efficiency. Outcome-oriented covariate selection, which involves selecting covariates related to the outcome, can enhance efficiency, even for propensity score (PS) methods. For outcome-oriented covariate selection in PS models, outcome-adaptive lasso (OAL) can be used for penalization with the oracle property. The performance of…

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