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Multidimensional Distributional Neural Network Output Demonstrated in Super-Resolution of Surface Wind Speed

多维分布神经网络输出及其在地表风速超分辨率中的应用

Accurate quantification of uncertainty in neural network predictions remains a central challenge for scientific applications involving high-dimensional, correlated data. While existing methods capture either aleatoric or epistemic uncertainty, few offer closed-form, multidimensional distributions that preserve spatial correlation while remaining computationally tractable. In this work, we present a framework for training neural networks with a multidimensional Gaussian loss,…

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High-dimensional Asymptotics of Generalization Performance in Continual Ridge Regression

持续岭回归泛化性能的高维渐近理论

Continual learning is motivated by the need to adapt to real-world dynamics in tasks and data distribution while mitigating catastrophic forgetting. Despite significant advances in continual learning techniques, the theoretical understanding of their generalization performance lags behind. This paper examines the theoretical properties of continual ridge regression in high-dimensional linear models, where the dimension is proportional to the sample size in each task. Using…

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Regularized e-processes: anytime valid inference with knowledge-based efficiency gains

正则化 e-过程:具有知识驱动效率增益的任意时刻有效推断

Classical statistical methods have theoretical justification when the sample size is predetermined. In applications, however, it's often the case that sample sizes are data-dependent rather than predetermined. The aforementioned methods aren't reliable in this latter case, hence the recent interest in e-processes and methods that are anytime valid, i.e., reliable for any dynamic data-collection plan. But if the investigator has relevant-yet-incomplete prior information about…

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Joint Quantile Shrinkage: A State-Space Approach toward Non-Crossing Bayesian Quantile Models

联合分位数收缩:面向非交叉贝叶斯分位数模型的状态空间方法

Crossing of fitted conditional quantiles is a prevalent problem for quantile regression models. We propose a new Bayesian modelling framework that penalises multiple quantile regression functions toward the desired non-crossing space. We achieve this by estimating multiple quantiles jointly with a prior on variation across quantiles, a fused shrinkage prior with quantile adaptivity. The posterior is derived from a decision-theoretic general Bayes perspective, whose form…

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Simultaneous Modeling of Disease Screening and Severity Prediction: A Multi-task and Sparse Regularization Approach

疾病筛查与严重程度预测的联合建模:多任务与稀疏正则化方法

Identifying clinically relevant biomarkers and developing predictive models are central challenges in biomedical research. Biomarkers are commonly used for disease screening, and some provide information not only on the presence or absence of a disease but also on its severity. Such biomarkers can contribute to treatment prioritization and support clinical decision-making. To address both disease screening and severity prediction, this paper focuses on regression modeling…

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Diffusion-Driven High-Dimensional Variable Selection

扩散模型驱动的高维变量选择

Variable selection for high-dimensional, highly correlated data has long been a challenging problem, often yielding unstable and unreliable models. We propose a resample-aggregate framework that exploits diffusion models' ability to generate high-fidelity synthetic data. Specifically, we draw multiple pseudo-data sets from a diffusion model fitted to the original data, apply any off-the-shelf selector (e.g., lasso or SCAD), and store the resulting inclusion indicators and…

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Parallel Network Reconstruction with Multi-directional Regularization

基于多方向正则化的并行网络重构

Reconstructing large-scale latent networks from observed dynamics is crucial for understanding complex systems. However, the existing methods based on compressive sensing are often rendered infeasible in practice by prohibitive computational and memory costs. To address this challenge, we introduce a new distributed computing framework for efficient large-scale network reconstruction with parallel computing, namely PALMS (Parallel Adaptive Lasso with Multi-directional…

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An Improved Solution to the Two Normal Means Problem via Regularization

正则化改进的两正态均值问题解

The many-normal-means problem is a classic example that motivates the development of many important inferential procedures in the history of statistics. In this short note, we consider a further special case of the problem, which involves only two normally distributed data points with a constraint that the pair of means are not too far apart from one another. Starting with a regularized ML estimator, we construct a novel possibilistic IM for marginal inference on one of the…

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Bayesian Double Machine Learning for Causal Inference

用于因果推断的贝叶斯双重机器学习

This paper proposes a simple, novel, and fully-Bayesian approach for causal inference in partially linear models with high-dimensional control variables. Off-the-shelf machine learning methods can introduce biases in the causal parameter known as regularization-induced confounding. To address this, we propose a Bayesian Double Machine Learning (BDML) method, which modifies a standard Bayesian multivariate regression model and recovers the causal effect of interest from the…

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A More Robust Approach to Multivariable Mendelian Randomization

多变量孟德尔随机化的一种更稳健方法

Multivariable Mendelian randomization (MVMR) uses genetic variants as instrumental variables to infer the direct effects of multiple exposures on an outcome. However, unlike univariable Mendelian randomization, MVMR often faces greater challenges with many weak instruments, which can lead to bias not necessarily toward zero and inflation of type I errors. In this work, we introduce a new asymptotic regime that allows exposures to have varying degrees of instrument strength,…

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A Consistent and Scalable Algorithm for Best Subset Selection in Single Index Models

单指标模型中最佳子集选择的一致且可扩展算法

Analysis of high-dimensional data has led to increased interest in both single index models (SIMs) and the best-subset selection. SIMs provide an interpretable and flexible modeling framework for high-dimensional data, while the best-subset selection aims to find a sparse model from a large set of predictors. However, the best-subset selection in high-dimensional models is known to be computationally intractable. Existing proxy algorithms are appealing but do not yield the…

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Asymptotic Optimism of Random-Design Linear and Kernel Regression Models

随机设计下线性与核回归模型的渐近乐观度

We derived the closed-form asymptotic optimism of linear regression models under random designs, and generalizes it to kernel ridge regression. Using scaled asymptotic optimism as a generic predictive model complexity measure, we studied the fundamental different behaviors of linear regression model, tangent kernel (NTK) regression model and three-layer fully connected neural networks (NN). Our contribution is two-fold: we provided theoretical ground for using scaled…

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Adaptive sparsening and smoothing of the treatment model for longitudinal causal inference using outcome-adaptive LASSO and marginal fused LASSO

纵向因果推断中治疗模型的自适应稀疏化与平滑

Causal variable selection in time-varying treatment settings is challenging due to evolving confounding effects. Existing methods mainly focus on time-fixed exposures and are not directly applicable to time-varying scenarios. We propose a novel two-step procedure for variable selection when modeling the treatment probability at each time point. We first introduce a novel approach to longitudinal confounder selection using a Longitudinal Outcome Adaptive LASSO (LOAL) that…

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Bayesian Models for Joint Selection of Features and Auto-Regressive Lags: Theory and Applications in Environmental and Financial Forecasting

特征与自回归滞后的贝叶斯联合选择:环境与金融预测应用

We develop a Bayesian framework for variable selection in linear regression with autocorrelated errors, accommodating lagged covariates and autoregressive structures. This setting occurs in time series applications where responses depend on contemporaneous or past explanatory variables and persistent stochastic shocks, including financial modeling, hydrological forecasting, and meteorological applications requiring temporal dependency capture. Our methodology uses…

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Partial identification via conditional linear programs: estimation and policy learning

基于条件线性规划的部分识别:估计与政策学习

Many important quantities of interest are only partially identified from observable data: the data can limit them to a set of plausible values, but not uniquely determine them. This paper develops a unified framework for covariate-assisted estimation, inference, and decision making in partial identification problems where the parameter of interest satisfies a series of linear constraints, conditional on covariates. In such settings, bounds on the parameter can be written as…

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High-dimensional Longitudinal Inference via a De-sparsified Dantzig-Selector

高维纵向数据下基于去稀疏化 Dantzig 选择器的统计推断

In this paper, we consider statistical inference with generalized linear models in high dimensions under a longitudinal clustered data framework. Specifically, we propose a de-sparsified version of an initial Dantzig-type regularized estimator in regression settings and provide theoretical justification for both linear and generalized linear models. We present extensive numerical simulations demonstrating the effectiveness of our method for continuous and binary data. For…

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A causal fused lasso for interpretable heterogeneous treatment effects estimation

用于可解释异质性处理效应估计的因果融合lasso

We propose a novel method for estimating heterogeneous treatment effects based on the fused lasso. By first ordering samples based on the propensity or prognostic score, we match units from the treatment and control groups. We then run the fused lasso to obtain piecewise constant treatment effects with respect to the ordering defined by the score. Similar to the existing methods based on discretizing the score, our methods yield interpretable subgroup effects. However,…

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Estimation and Inference in High-Dimensional Panel Data Models with Interactive Fixed Effects

含交互固定效应的高维面板数据模型:估计与推断

We develop new econometric methods for estimation and inference in high-dimensional panel data models with interactive fixed effects. Our approach can be regarded as a non-trivial extension of the very popular common correlated effects (CCE) approach. Roughly speaking, we proceed as follows: We first construct a projection device to eliminate the unobserved factors from the model by applying a dimensionality reduction transform to the matrix of cross-sectionally averaged…

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Bayesian MI-LASSO for Variable Selection on Multiply-Imputed Data

多重插补数据的贝叶斯MI-LASSO变量选择

Multiple imputation is widely used for handling missing data in real-world applications. For variable selection on multiply-imputed datasets, however, if selection is performed on each imputed dataset separately, it can result in different sets of selected variables across datasets. MI-LASSO, one of the most commonly used approaches to this problem, regards the same variable across all separate imputed datasets as a group variable and exploits the group LASSO to yield a…

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A New Perspective on High Dimensional Confidence Intervals

高维置信区间的新视角

Classically, confidence intervals are required to have consistent coverage across all values of the parameter. However, this will inevitably break down if the underlying estimation procedure is biased. For this reason, many efforts have focused on debiased versions of the lasso for interval construction. In the process of debiasing, however, the connection to the original estimates are often obscured. In this work, we offer a different perspective focused on average coverage…

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Estimation and variable selection in high dimension in a causal joint model of survival times and longitudinal outcomes with random effects

带随机效应的生存时间与纵向结果因果联合模型:高维估计与变量选择

We consider a joint survival and mixed-effects model to explain the survival time from longitudinal data and high-dimensional covariates in a population. The longitudinal data is modeled using a non linear mixed-effects model to account for the inter-individual variability in the population. The corresponding regression function serves as a link function incorporated into the survival model. In that way, the longitudinal data is related to the survival time. We consider a…

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Estimation and variable selection in high dimension in nonlinear mixed-effects models

高维非线性混合效应模型中的估计与变量选择

We consider nonlinear mixed effects models including high-dimensional covariates to model individual parameters variability. The objective is to identify relevant covariates among a large set under sparsity assumption and to estimate model parameters. To face the high dimensional setting we consider a regularized estimator namely the maximum likelihood estimator penalized with the l1-penalty. We rely on the use of the eBIC model choice criteria to select an optimal reduced…

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Bagged Regularized $k$-Distances for Anomaly Detection

基于Bagged正则化k距离的异常检测

We consider the paradigm of unsupervised anomaly detection, which involves the identification of anomalies within a dataset in the absence of labeled examples. Though distance-based methods are top-performing for unsupervised anomaly detection, they suffer heavily from the sensitivity to the choice of the number of the nearest neighbors. In this paper, we propose a new distance-based algorithm called bagged regularized $k$-distances for anomaly detection (BRDAD), converting…

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Graph-based Square-Root Estimation for Sparse Linear Regression

基于图的平方根估计用于稀疏线性回归

Sparse linear regression is one of the classic problems in the field of statistics, which has deep connections and high intersections with optimization, computation, and machine learning. To address the effective handling of high-dimensional data, the diversity of real noise, and the challenges in estimating standard deviation of the noise, we propose a novel and general graph-based square-root estimation (GSRE) model for sparse linear regression. Specifically, we use…

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