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Efficiently Learning Synthetic Control Models for High-dimensional Disaggregated Data

高维细分数据中合成控制模型的高效学习

The Synthetic Control method (SC) has become a valuable tool for estimating causal effects. Originally designed for single-treated unit scenarios, it has recently found applications in high-dimensional disaggregated settings with multiple treated units. However, challenges in practical implementation and computational efficiency arise in such scenarios. To tackle these challenges, we propose a novel approach that integrates the Multivariate Square-root Lasso method into the…

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Causal Effect Estimation with TMLE: Handling Missing Data and Near-Violations of Positivity

TMLE 因果效应估计:缺失数据与近正值性违背

We evaluate the performance of targeted maximum likelihood estimation (TMLE) for estimating the average treatment effect in missing data scenarios under varying levels of positivity violations. We employ model- and design-based simulations, with the latter using undersmoothed highly adaptive lasso on the 'WASH Benefits Bangladesh' dataset to mimic real-world complexities. Five missingness-directed acyclic graphs are considered, capturing common missing data mechanisms in…

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Optimal Nuisance Function Tuning for Estimating a Doubly Robust Functional under Proportional Asymptotics

比例渐近下双重稳健泛函估计的最优干扰函数调参

In this paper, we explore the asymptotically optimal tuning parameter choice in ridge regression for estimating nuisance functions of a statistical functional that has recently gained prominence in conditional independence testing and causal inference. Given a sample of size $n$, we study estimators of the Expected Conditional Covariance (ECC) between variables $Y$ and $A$ given a high-dimensional covariate $X \in \mathbb{R}^p$. Under linear regression models for $Y$ and $A$…

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To MCMC or not to MCMC: Evaluating non-MCMC methods for Bayesian penalized regression

用还是不用 MCMC:贝叶斯惩罚回归中非 MCMC 方法的评估

Markov Chain Monte Carlo (MCMC) sampling is computationally expensive, especially for complex models. Alternative methods make simplifying assumptions about the posterior to reduce computational burden, but their impact on predictive performance remains unclear. This paper compares MCMC and non-MCMC methods for high-dimensional penalized regression, examining when computational shortcuts are justified for prediction tasks. We conduct a comprehensive simulation study using…

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Variable Selection for Fixed and Random Effects in Multilevel Functional Mixed Effects Models

多层函数混合效应模型中的固定效应与随机效应变量选择

We develop a new method for simultaneously selecting fixed and random effects in a multilevel functional regression model. The proposed method is motivated by accelerometer-derived physical activity data from the 2011-12 cohort of the National Health and Nutrition Examination Survey (NHANES), where we are interested in identifying age and race-specific heterogeneity in covariate effects on the diurnal patterns of physical activity across the lifespan. Existing methods for…

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ROTI-GCV: Generalized Cross-Validation for right-ROTationally Invariant Data

ROTI-GCV:面向右旋转不变数据的广义交叉验证

Two key tasks in high-dimensional regularized regression are tuning the regularization strength for accurate predictions and estimating the out-of-sample risk. It is known that the standard approach -- $k$-fold cross-validation -- is inconsistent in modern high-dimensional settings. While leave-one-out and generalized cross-validation remain consistent in some high-dimensional cases, they become inconsistent when samples are dependent or contain heavy-tailed covariates. As a…

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Estimation of causal dose-response functions under data fusion

数据融合下因果剂量反应函数的估计

Estimating the causal dose-response function is challenging, particularly when data from a single source are insufficient to estimate responses precisely across all exposure levels. To overcome this limitation, we propose a data fusion framework that leverages multiple data sources that are partially aligned with the target distribution. Specifically, we derive a Neyman-orthogonal loss function tailored for estimating the dose-response function within data fusion settings.…

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COADVISE: Covariate Adjustment with Variable Selection in Randomized Controlled Trials

COADVISE:随机对照试验中结合变量选择的协变量调整

Adjusting for covariates in randomized controlled trials can enhance the credibility and efficiency of treatment effect estimation. However, handling numerous covariates and their complex (non-linear) transformations poses a challenge. Motivated by the case study of the Best Apnea Interventions for Research (BestAIR) trial data from the National Sleep Research Resource (NSRR), where the number of covariates (p=114) is comparable to the sample size (N=196), we propose a…

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A Unified Framework for Pattern Recovery in Penalized and Thresholded Estimation and its Geometry

惩罚与阈值估计中模式恢复的统一框架及其几何

We consider the framework of penalized estimation where the penalty term is given by a real-valued polyhedral gauge, which encompasses methods such as LASSO, generalized LASSO, SLOPE, OSCAR, PACS and others. Each of these estimators is defined through an optimization problem and can uncover a different structure or ``pattern'' of the unknown parameter vector. We define a novel and general notion of patterns based on subdifferentials and formalize an approach to measure…

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Variable Selection with Broken Adaptive Ridge Regression for Interval-Censored Competing Risks Data

区间删失竞争风险数据的断裂自适应岭回归变量选择

Competing risks data refer to situations where the occurrence of one event pre- cludes the possibility of other events happening, resulting in multiple mutually exclusive events. This data type is commonly encountered in medical research and clinical trials, exploring the interplay between different events and informing decision-making in fields such as healthcare and epidemiology. We develop a penal- ized variable selection procedure to handle such complex data in an…

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Causal Inference in High-Dimensional Generalized Linear Models with Binary Outcomes

二元结果高维广义线性模型中的因果推断

This paper proposes a debiased estimator for causal effects in high-dimensional generalized linear models with binary outcomes and general link functions. The estimator augments a regularized regression plug-in with weights computed from a convex optimization problem that approximately balances link-derivative-weighted covariates and controls variance; it does not rely on estimated propensity scores. Under standard conditions, the estimator is $\sqrt{n}$-consistent and…

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Selecting the Best Arm in One-Shot Multi-Arm RCTs: The Asymptotic Minimax-Regret Decision Framework for the Best-Population Selection Problem

一次性多臂随机试验的最佳方案选择:渐近极小极大遗憾决策框架

We develop a frequentist decision-theoretic framework for selecting the best arm in one-shot, multi-arm randomized controlled trials (RCTs). Our approach characterizes the minimax-regret (MMR) optimal decision rule for any multivariate location family reward distribution with full support. We show that the MMR rule is deterministic, unique, and computationally tractable. We then specialize to the case of multivariate normal (MVN) rewards with an arbitrary covariance matrix,…

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Adaptive Influence Diagnostics in High-Dimensional Regression

高维回归中的自适应影响诊断

An adaptive Cook's distance (ACD) for diagnosing influential observations in high-dimensional single-index models with multicollinearity and outlier contamination is proposed. ACD is a model-free technique built on sparse local linear gradients to temper leverage effects. In simulations spanning low- and high-dimensional design settings with strong correlation, ACD based on LASSO (ACD-LASSO) and SCAD (ACD-SCAD) penalties reduced masking and swamping relative to classical…

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Regression Model Selection Under General Conditions

一般条件下的回归模型选择

Model selection criteria are one of the most important tools in statistics. Proofs showing a model selection criterion is asymptotically optimal are tailored to the type of model (linear regression, quantile regression, penalized regression, etc.), the estimation method (linear smoothers, maximum likelihood, generalized method of moments, etc.), the type of data (i.i.d., dependent, high dimensional, etc.), and the type of model selection criterion. Moreover, assumptions are…

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Treatment Effects Inference with High-Dimensional Instruments and Control Variables

高维工具变量与控制变量下的处理效应推断

Obtaining valid treatment effect inference remains a challenging problem when dealing with numerous instruments and non-sparse control variables. In this paper, we propose a novel ridge regularization-based instrumental variables method for estimation and inference in the presence of both high-dimensional instrumental variables and high-dimensional control variables. These methods are applicable both with and without sparsity assumptions. To remove the estimation bias, we…

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Factor-augmented sparse MIDAS regressions with an application to nowcasting

因子增强的稀疏 MIDAS 回归及即时预测应用

This article investigates factor-augmented sparse MIDAS (Mixed Data Sampling) regressions for high-dimensional time series data, which may be observed at different frequencies. Our novel approach integrates sparse and dense dimensionality reduction techniques. We derive the convergence rate of our estimator under misspecification due to the MIDAS approximation error, $τ$-mixing dependence, and polynomial tails. Our method's finite sample performance is assessed via Monte…

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Constructing Confidence Intervals for Infinite-Dimensional Functional Parameters by Highly Adaptive Lasso

利用高度自适应 Lasso 构造无限维函数参数的置信区间

Estimating the conditional mean function is a central task in statistical learning. In this paper, we consider estimation and inference for a nonparametric class of real-valued cadlag functions with bounded sectional variation (Gill et al., 1995), using the Highly Adaptive Lasso (HAL) (van der Laan, 2015; Benkeser and van der Laan, 2016; van der Laan, 2023), a flexible empirical risk minimizer over linear combinations of tensor products of zero- or higher-order spline basis…

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$\ell_1$-Regularized Generalized Least Squares

ℓ1 正则化广义最小二乘估计

We study an $\ell_{1}$-regularized generalized least-squares (GLS) estimator for high-dimensional regressions with autocorrelated errors. Specifically, we consider the case where errors are assumed to follow an autoregressive process, alongside a feasible variant of GLS that estimates the structure of this process in a data-driven manner. The estimation procedure consists of three steps: performing a LASSO regression, fitting an autoregressive model to the realized…

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Causal inference of post-transcriptional regulation timelines from long-read sequencing in Arabidopsis thaliana

利用拟南芥长读长测序推断转录后调控时间线

We propose a novel framework for reconstructing the chronology of genetic regulation using causal inference based on Pearl's theory. The approach proceeds in three main stages: causal discovery, causal inference, and chronology construction. We apply it to the ndhB and ndhD genes of the chloroplast in Arabidopsis thaliana, generating four alternative maturation timeline models per gene, each derived from a different causal discovery algorithm (HC, PC, LiNGAM, or NOTEARS).…

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Regularized Sparse Optimal Discriminant Clustering

正则化稀疏最优判别聚类

We propose a new method based on sparse optimal discriminant clustering (SODC), incorporating a penalty term into the scoring matrix based on convex clustering. With the addition of this penalty term, it is expected to improve the accuracy of cluster identification by pulling points within the same cluster closer together and points from different clusters further apart. When the estimation results are visualized, the clustering structure can be depicted more clearly.…

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Sliding-Window Signatures for Time Series: Application to Electricity Demand Forecasting

时间序列的滑动窗口签名特征:电力需求预测应用

Nonlinear and delayed effects of covariates often render time series forecasting challenging. To this end, we propose a novel forecasting framework based on ridge regression with signature features calculated on sliding windows. These features capture complex temporal dynamics without relying on learned or hand-crafted representations. Focusing on the discrete-time setting, we establish theoretical guarantees, namely universality of approximation and stationarity of…

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Effective regions and kernels in continuous sparse regularisation, with application to sketched mixtures

连续稀疏正则化中的有效区域与核:在草图混合模型中的应用

This paper advances the general theory of continuous sparse regularisation on measures with the Beurling-LASSO (BLASSO). This TV-regularised convex program on the space of measures allows to recover a sparse measure using a noisy observation from a measurement operator. While previous works have uncovered the central role played by this operator and its associated kernel in order to get estimation error bounds, the latter requires a technical local positive curvature (LPC)…

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Developing an information criterion for spatial data analysis through Bayesian generalized fused lasso

面向空间数据分析的贝叶斯广义融合套索信息准则

In the field of spatial data analysis, spatially varying coefficients (SVC) models, which allow regression coefficients to vary by region and flexibly capture spatial heterogeneity, have continued to be developed in various directions. Moreover, the Bayesian generalized fused lasso is often used as a method that efficiently provides estimation under the natural assumption that regression coefficients of adjacent regions tend to take the same value. In most Bayesian methods,…

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Macroeconomic Forecasting and Machine Learning

宏观经济预测与机器学习

We forecast the full conditional distribution of macroeconomic outcomes by systematically integrating three key principles: using high-dimensional data with appropriate regularization, adopting rigorous out-of-sample validation procedures, and incorporating nonlinearities. By exploiting the rich information embedded in a large set of macroeconomic and financial predictors, we produce accurate predictions of the entire profile of macroeconomic risk in real time. Our findings…

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