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The Conjugate Domain Dichotomy: Exact Risk of M-Estimators under Infinite-Variance Noise in High Dimensions

共轭域二分法:高维无限方差噪声下M估计的精确风险

This paper studies high-dimensional M-estimation in the proportional asymptotic regime (p/n -> gamma > 0) when the noise distribution has infinite variance. For noise with regularly-varying tails of index alpha in (1,2), we establish that the asymptotic behavior of a regularized M-estimator is governed by a single geometric property of the loss function: the boundedness of the domain of its Fenchel conjugate. When this conjugate domain is bounded -- as is the case for the…

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Identifying Genetic Variants for Obesity: A Knowledge Integration Quantile Regression (KIQR) Approach for Ultra-High-Dimensional Data

面向肥胖遗传变异的超高维数据知识整合分位数回归方法

Obesity is widely recognized as a serious and pervasive health concern. We study obesity through body mass index (BMI), which is known to be highly heritable, and identify important genetic risk factors for BMI from hundreds of thousands of single nucleotide polymorphisms (SNPs) in the Framingham Study data. Several challenges arise when using traditional genome-wide association studies (GWAS): (1) They suffer from a low power due to a combination of a limited number of…

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Vertical Consensus Inference for High-Dimensional Random Partition

高维随机划分的纵向共识推断

We review recently proposed Bayesian approaches for clustering high-dimensional data. After identifying the main limitations of available approaches, we introduce an alternative framework based on vertical consensus inference (VCI) to mitigate the curse of dimensionality in high-dimensional Bayesian clustering. VCI builds on the idea of consensus Monte Carlo by dividing the data into multiple shards (smaller subsets of variables), performing posterior inference on each…

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Diffolio: A Diffusion Model for Multivariate Probabilistic Financial Time-Series Forecasting and Portfolio Construction

Diffolio:多变量金融时序概率预测与组合构建的扩散模型

Probabilistic forecasting is crucial in multivariate financial time-series for constructing efficient portfolios that account for complex cross-sectional dependencies. In this paper, we propose Diffolio, a diffusion model designed for multivariate financial time-series forecasting and portfolio construction. Diffolio employs a denoising network with a hierarchical attention architecture, comprising both asset-level and market-level layers. Furthermore, to better reflect…

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Robust regularized covariance matrix estimation: well-posedness and convergent algorithm

稳健正则化协方差矩阵估计:适定性与收敛算法

In this paper, we study properties of penalized and structured M-estimators of multivariate scatter, based on geodesically convex but not necessarily smooth penalty functions. Existence and uniqueness conditions for these penalized and structured estimators are given. However, we show that the standard fixed-point algorithm which is usually applied to an M-estimation problem does not necessarily converge for penalized M-estimation problems. Hence, we develop a new but simple…

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Bayesian Variable Selection for Function-on-Scalar Regression Models: a comparative analysis

函数型因变量回归的贝叶斯变量选择:比较分析

In this work, we developed a new Bayesian method for variable selection in function-on-scalar regression (FOSR). Our method uses a hierarchical Bayesian structure and latent variables to enable an adaptive covariate selection process for FOSR. Extensive simulation studies show the proposed method's main properties, such as its accuracy in estimating the coefficients and high capacity to select variables correctly. Furthermore, we conducted a substantial comparative analysis…

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Mediation analysis with unmeasured confounding between parallel mediators and outcome

平行中介与结果之间存在未测混杂的中介分析

Mediation analysis extending beyond single mediators has gained significant attention in recent years. However, related methods often assume the absence of unmeasured mediator-outcome confounding. To address this, we develop a mediation analysis framework that accounts for such confounding within a linear structural equation model with parallel mediators. Specifically, we introduce a pseudo proxy variable to capture unmeasured confounding, allowing us to identify causal…

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Parameter Estimation in Stochastic Differential Equations via Wiener Chaos Expansion and Stochastic Gradient Descent

基于维纳混沌展开与随机梯度下降的随机微分方程参数估计

This study addresses the inverse problem of parameter estimation for Stochastic Differential Equations (SDEs) by minimizing a regularized discrepancy functional via Stochastic Gradient Descent (SGD). To achieve computational efficiency, we leverage the Wiener Chaos Expansion (WCE), a spectral decomposition technique that projects the stochastic solution onto an orthogonal basis of Hermite polynomials. This transformation effectively maps the stochastic dynamics into a…

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Boosting multi-view association testing via devariation

通过去变异预处理增强多视图关联检验

Understanding the interplay between high-dimensional data from different views is essential in biomedical research, particularly in fields such as genomics, neuroimaging and biobank-scale studies involving high-dimensional features. Existing statistical tests for the association between two random vectors often do not fully capture dependencies between views due to limitations in modeling within-view dependencies, particularly in high-dimensional data without clear…

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Targeted learning of heterogeneous treatment effect curves for right censored or left truncated time-to-event data

右删失或左截断生存数据中异质处理效应曲线的目标学习

In recent years, there has been growing interest in causal machine learning estimators for quantifying subject-specific effects of a binary treatment on time-to-event outcomes. Estimation approaches have been proposed which attenuate the inherent regularisation bias in machine learning predictions, with each of these estimators addressing measured confounding, right censoring, and in some cases, left truncation. However, the existing approaches are found to exhibit…

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Estimation of projection operators with Gaussian noise

高斯噪声下投影算子的估计

This paper focuses on random projection operators when the subspace of projection is estimated. We derive non-asymptotic upper bounds on the error between the projection onto the estimated subspace and the projection onto the underlying subspace. The provided upper bounds depend on the noise and on intrinsic properties of the estimated subspace. Several scenarios are considered according to the distribution of the estimator of the matrix spanning the subspace. The…

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Regularized Regression by Composition: Identifiability, Structured Penalization, and Statistical Guarantees for Multi-Flow Distributional Models

基于复合的正则化回归:多流分布模型的可识别性、结构化惩罚与统计保证

Regression by composition provides a flexible framework for constructing conditional distributions through sequential group actions. However, when multiple flows act on the same distribution, the model becomes non-identifiable, leading to flat likelihood regions and unstable estimates. We introduce a structured regularization framework that resolves this issue by assigning flow-specific penalties. The resulting estimator is defined as a penalized maximum likelihood problem…

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Modeling with Categorical Features via Exact Fusion and Sparsity Regularisation

分类特征的精确融合与稀疏正则化建模

We study the high-dimensional linear regression problem with categorical predictors that have many levels. We propose a new estimation approach, which performs model compression via two mechanisms by simultaneously encouraging (a) clustering of the regression coefficients to collapse some of the categorical levels together; and (b) sparsity of the regression coefficients. We present novel mixed integer programming formulations for our estimator, and develop a custom row…

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Optimization-centric cutting feedback for semiparametric models

半参数模型中以优化为中心的反馈切断方法

Complex statistical models are often built by combining multiple submodels, called modules. Here we consider modular inference where the modules contain both parametric and nonparametric components. In such cases, standard Bayesian inference can be highly sensitive to misspecification in any module, and influential prior specifications for the nonparametric components can compromise inference for the parametric components, and vice versa. We propose a novel…

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Discrete Causal Representation Learning

离散因果表示学习

Causal representation learning seeks to uncover causal relationships among high-level latent variables from low-level, entangled, and noisy observations. Existing approaches often either rely on deep neural networks, which lack interpretability and formal guarantees, or impose restrictive assumptions like linearity, continuous-only observations, and strong structural priors. These limitations particularly challenge applications with a large number of discrete latent…

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Post-selection inference in generalized linear models via parametric programming

广义线性模型中基于参数规划的选择后推断

We propose a unified framework to draw inferences for regression coefficients in a generalized linear model (GLM) following Lasso-based variable selection. We adapt to non-Gaussian GLMs a recently developed parametric programming strategy for post-selection inference in the linear model with a Gaussian response by drawing parallels between maximum likelihood estimation in GLMs and least squares estimation in linear models. We then conduct post-selection inference based on a…

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Robust Matrix Estimation with Side Information

利用辅助信息的稳健矩阵估计

We introduce a flexible framework for high-dimensional matrix estimation to incorporate side information for both rows and columns. Existing approaches, such as inductive matrix completion, often impose restrictive structure-for example, an exact low-rank covariate interaction term, linear covariate effects, and limited ability to exploit components explained only by one side (row or column) or by neither-and frequently omit an explicit noise component. To address these…

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Identification and Bayesian Inference for Synthetic Control Methods with Spillover Effects

存在溢出效应的合成控制方法:识别与贝叶斯推断

The synthetic control method (SCM) is widely used for causal inference with panel data, particularly when the number of treated units is small. It relies on the stable unit treatment value assumption (SUTVA), ruling out spillover effects. However, interventions often affect not only treated but also untreated units. This study proposes a novel panel data method that extends standard SCM to account for spillovers and estimate both treatment and spillover effects. The approach…

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Regularized Estimation of the Loading Matrix in Factor Models for High-Dimensional Time Series

高维时间序列因子模型载荷矩阵的正则化估计

High-dimensional data analysis using traditional models suffers from overparameterization. Two types of techniques are commonly used to reduce the number of parameters - regularization and dimension reduction. In this project, we combine them by imposing a sparse factor structure and propose a regularized estimator to further reduce the number of parameters in factor models. A challenge limiting the widespread application of factor models is that factors are hard to…

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Sparse Learning and Class Probability Estimation with Weighted Support Vector Machines

加权支持向量机的稀疏学习与类别概率估计

Classification and probability estimation are fundamental tasks with broad applications across modern machine learning and data science, spanning fields such as biology, medicine, engineering, and computer science. Recent development of weighted Support Vector Machines (wSVMs) has demonstrated considerable promise in robustly and accurately predicting class probabilities and performing classification across a variety of problems (Wang et al., 2008). However, the existing…

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Bayesian variable selection in sample selection models using spike-and-slab priors

样本选择模型中的贝叶斯变量选择:spike-and-slab 先验

Sample selection models are a widely used approach for correcting bias caused by data that are missing not at random. Their formulation requires specifying the variables that influence the outcome and those that drive the selection process. This specification is often based on expert knowledge, which can result in the inclusion of irrelevant variables or the omission of important ones. Moreover, to avoid inferential problems such as practical non-identifiability,…

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Riesz Regression As Direct Density Ratio Estimation

将 Riesz 回归理解为直接密度比估计

This study clarifies the relationship between Riesz regression [Chernozhukov et al., 2021] and density ratio estimation (DRE) in causal inference problems, such as average treatment effect estimation. We first show that the Riesz representer can be written as a signed density ratio and then demonstrate that the Riesz regression objective coincides with the least-squares importance fitting criterion [Kanamori et al., 2009]. Although Riesz regression applies to a broad class…

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Adversarially Perturbed Precision Matrix Estimation

对抗扰动下的精度矩阵估计

Precision matrix estimation is a fundamental topic in multivariate statistics and modern machine learning. This paper proposes an adversarially perturbed precision matrix estimation framework, motivated by recent developments in adversarial training. The proposed framework is versatile for the precision matrix problem since, by adapting to different perturbation geometries, the proposed framework can not only recover the existing distributionally robust method but also…

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Proof of The TAP Free Energy for High-Dimensional Linear Regression with Spherical Priors at All Temperatures

全温度下球面先验高维线性回归的 TAP 自由能证明

Approximate inference is central to Bayesian learning, with variational inference (VI) providing a scalable framework for posterior approximation. While mean-field VI often fails in high dimensions, the more refined Bethe approximation, equivalent to the Thouless-Anderson-Palmer (TAP) free energy in statistical physics, has long been conjectured to capture Bayes-optimal behavior. We prove that the TAP formula holds for Bayesian linear regression with a uniform spherical…

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