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Semi-parametric estimation of biomarker age trends with endogenous medication use in longitudinal data

内生用药下纵向生物标志物年龄趋势的半参数估计

In cohort studies, non-random medication use can pose barriers to estimation of the natural history trend in a mean biomarker value (namely, the association between a predictor of interest and a biomarker outcome that would be observed in the absence of biomarker-specific treatment). Common causes of treatment and outcomes are often unmeasured, obscuring our ability to easily account for medication use with commonly invoked assumptions such as ignorability. Further, absent…

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When the ends don't justify the means: Learning a treatment strategy to prevent harmful indirect effects

当结果不足以证明手段合理:学习避免有害间接效应的治疗策略

There is a growing literature on finding so-called optimal treatment rules, which are rules by which to assign treatment to individuals based on an individual's characteristics, such that a desired outcome is maximized. A related goal entails identifying individuals who are predicted to have a harmful indirect effect (the effect of treatment on an outcome through mediators) even in the presence of an overall beneficial effect of the treatment on the outcome. In some cases,…

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Kernel-Distance-Based Covariate Balancing

基于核距离的协变量平衡

A common concern in observational studies focuses on properly evaluating the causal effect, which usually refers to the average treatment effect or the average treatment effect on the treated. In this paper, we propose a data preprocessing method, the Kernel-distance-based covariate balancing, for observational studies with binary treatments. This proposed method yields a set of unit weights for the treatment and control groups, respectively, such that the reweighted…

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Regression Discontinuity Design with Many Thresholds

具有多个阈值的断点回归设计

Numerous empirical studies employ regression discontinuity designs with multiple cutoffs and heterogeneous treatments. A common practice is to normalize all the cutoffs to zero and estimate one effect. This procedure identifies the average treatment effect (ATE) on the observed distribution of individuals local to existing cutoffs. However, researchers often want to make inferences on more meaningful ATEs, computed over general counterfactual distributions of individuals,…

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COVID-19 spreading in financial networks: A semiparametric matrix regression model

COVID-19 在金融网络中的传播:半参数矩阵回归模型

Network models represent a useful tool to describe the complex set of financial relationships among heterogeneous firms in the system. In this paper, we propose a new semiparametric model for temporal multilayer causal networks with both intra- and inter-layer connectivity. A Bayesian model with a hierarchical mixture prior distribution is assumed to capture heterogeneity in the response of the network edges to a set of risk factors including the European COVID-19 cases. We…

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Average Density Estimators: Efficiency and Bootstrap Consistency

平均密度估计量:效率与 Bootstrap 一致性

This paper highlights a tension between semiparametric efficiency and bootstrap consistency in the context of a canonical semiparametric estimation problem, namely the problem of estimating the average density. It is shown that although simple plug-in estimators suffer from bias problems preventing them from achieving semiparametric efficiency under minimal smoothness conditions, the nonparametric bootstrap automatically corrects for this bias and that, as a result, these…

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Robust Forecasting

稳健预测

We use a decision-theoretic framework to study the problem of forecasting discrete outcomes when the forecaster is unable to discriminate among a set of plausible forecast distributions because of partial identification or concerns about model misspecification or structural breaks. We derive "robust" forecasts which minimize maximum risk or regret over the set of forecast distributions. We show that for a large class of models including semiparametric panel data models for…

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Boosting: Why You Can Use the HP Filter

Boosting:为何可以使用 HP 滤波器

The Hodrick-Prescott (HP) filter is one of the most widely used econometric methods in applied macroeconomic research. Like all nonparametric methods, the HP filter depends critically on a tuning parameter that controls the degree of smoothing. Yet in contrast to modern nonparametric methods and applied work with these procedures, empirical practice with the HP filter almost universally relies on standard settings for the tuning parameter that have been suggested largely by…

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Local Linear Forests

局部线性森林

Random forests are a powerful method for non-parametric regression, but are limited in their ability to fit smooth signals, and can show poor predictive performance in the presence of strong, smooth effects. Taking the perspective of random forests as an adaptive kernel method, we pair the forest kernel with a local linear regression adjustment to better capture smoothness. The resulting procedure, local linear forests, enables us to improve on asymptotic rates of…

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Quasi-Oracle Estimation of Heterogeneous Treatment Effects

异质性处理效应的准预言机估计

Flexible estimation of heterogeneous treatment effects lies at the heart of many statistical challenges, such as personalized medicine and optimal resource allocation. In this paper, we develop a general class of two-step algorithms for heterogeneous treatment effect estimation in observational studies. We first estimate marginal effects and treatment propensities in order to form an objective function that isolates the causal component of the signal. Then, we optimize this…

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Locally Robust Semiparametric Estimation

局部稳健的半参数估计

Many economic and causal parameters depend on nonparametric or high dimensional first steps. We give a general construction of locally robust/orthogonal moment functions for GMM, where moment conditions have zero derivative with respect to first steps. We show that orthogonal moment functions can be constructed by adding to identifying moments the nonparametric influence function for the effect of the first step on identifying moments. Orthogonal moments reduce model…

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Bootstrap-Based Inference for Cube Root Asymptotics

立方根渐近下的自助法推断

This paper proposes a valid bootstrap-based distributional approximation for M-estimators exhibiting a Chernoff (1964)-type limiting distribution. For estimators of this kind, the standard nonparametric bootstrap is inconsistent. The method proposed herein is based on the nonparametric bootstrap, but restores consistency by altering the shape of the criterion function defining the estimator whose distribution we seek to approximate. This modification leads to a generic and…

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Doubly Robust Difference-in-Differences Estimators

双重稳健的双重差分估计量

This article proposes doubly robust estimators for the average treatment effect on the treated (ATT) in difference-in-differences (DID) research designs. In contrast to alternative DID estimators, the proposed estimators are consistent if either (but not necessarily both) a propensity score or outcome regression working models are correctly specified. We also derive the semiparametric efficiency bound for the ATT in DID designs when either panel or repeated cross-section…

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Covariate Distribution Balance via Propensity Scores

通过倾向得分实现协变量分布平衡

This paper proposes new estimators for the propensity score that aim to maximize the covariate distribution balance among different treatment groups. Heuristically, our proposed procedure attempts to estimate a propensity score model by making the underlying covariate distribution of different treatment groups as close to each other as possible. Our estimators are data-driven, do not rely on tuning parameters such as bandwidths, admit an asymptotic linear representation, and…

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Nonparametric Tests for Treatment Effect Heterogeneity with Duration Outcomes

持续时间结果下处理效应异质性的非参数检验

This article proposes different tests for treatment effect heterogeneity when the outcome of interest, typically a duration variable, may be right-censored. The proposed tests study whether a policy 1) has zero distributional (average) effect for all subpopulations defined by covariate values, and 2) has homogeneous average effect across different subpopulations. The proposed tests are based on two-step Kaplan-Meier integrals and do not rely on parametric distributional…

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Optimal Bandwidth Choice for Robust Bias Corrected Inference in Regression Discontinuity Designs

断点回归中稳健偏差修正推断的最优带宽选择

Modern empirical work in Regression Discontinuity (RD) designs often employs local polynomial estimation and inference with a mean square error (MSE) optimal bandwidth choice. This bandwidth yields an MSE-optimal RD treatment effect estimator, but is by construction invalid for inference. Robust bias corrected (RBC) inference methods are valid when using the MSE-optimal bandwidth, but we show they yield suboptimal confidence intervals in terms of coverage error. We establish…

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Boosting High Dimensional Predictive Regressions with Time Varying Parameters

时变参数高维预测回归的提升算法

High dimensional predictive regressions are useful in wide range of applications. However, the theory is mainly developed assuming that the model is stationary with time invariant parameters. This is at odds with the prevalent evidence for parameter instability in economic time series, but theories for parameter instability are mainly developed for models with a small number of covariates. In this paper, we present two $L_2$ boosting algorithms for estimating high…

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Characteristic-Sorted Portfolios: Estimation and Inference

按特征排序的投资组合:估计与推断

Portfolio sorting is ubiquitous in the empirical finance literature, where it has been widely used to identify pricing anomalies. Despite its popularity, little attention has been paid to the statistical properties of the procedure. We develop a general framework for portfolio sorting by casting it as a nonparametric estimator. We present valid asymptotic inference methods and a valid mean square error expansion of the estimator leading to an optimal choice for the number of…

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Semiparametric Estimation of Structural Functions in Nonseparable Triangular Models

非可分三角模型中结构函数的半参数估计

Triangular systems with nonadditively separable unobserved heterogeneity provide a theoretically appealing framework for the modelling of complex structural relationships. However, they are not commonly used in practice due to the need for exogenous variables with large support for identification, the curse of dimensionality in estimation, and the lack of inferential tools. This paper introduces two classes of semiparametric nonseparable triangular models that address these…

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Cross-Validation, Risk Estimation, and Model Selection

交叉验证、风险估计与模型选择

Cross-validation is a popular non-parametric method for evaluating the accuracy of a predictive rule. The usefulness of cross-validation depends on the task we want to employ it for. In this note, I discuss a simple non-parametric setting, and find that cross-validation is asymptotically uninformative about the expected test error of any given predictive rule, but allows for asymptotically consistent model selection. The reason for this phenomenon is that the leading-order…

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A Random Attention Model

随机注意力模型

This paper illustrates how one can deduce preference from observed choices when attention is not only limited but also random. In contrast to earlier approaches, we introduce a Random Attention Model (RAM) where we abstain from any particular attention formation, and instead consider a large class of nonparametric random attention rules. Our model imposes one intuitive condition, termed Monotonic Attention, which captures the idea that each consideration set competes for the…

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lspartition: Partitioning-Based Least Squares Regression

lspartition:基于分区的最小二乘回归

Nonparametric partitioning-based least squares regression is an important tool in empirical work. Common examples include regressions based on splines, wavelets, and piecewise polynomials. This article discusses the main methodological and numerical features of the R software package lspartition, which implements modern estimation and inference results for partitioning-based least squares (series) regression estimation. This article discusses the main methodological and…

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Semi-Parametric Efficient Policy Learning with Continuous Actions

连续行动下的半参数有效策略学习

We consider off-policy evaluation and optimization with continuous action spaces. We focus on observational data where the data collection policy is unknown and needs to be estimated. We take a semi-parametric approach where the value function takes a known parametric form in the treatment, but we are agnostic on how it depends on the observed contexts. We propose a doubly robust off-policy estimate for this setting and show that off-policy optimization based on this…

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Simple Local Polynomial Density Estimators

简便的局部多项式密度估计量

This paper introduces an intuitive and easy-to-implement nonparametric density estimator based on local polynomial techniques. The estimator is fully boundary adaptive and automatic, but does not require pre-binning or any other transformation of the data. We study the main asymptotic properties of the estimator, and use these results to provide principled estimation, inference, and bandwidth selection methods. As a substantive application of our results, we develop a novel…

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