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Weighted Euclidean balancing for a matrix exposure in estimating causal effect

矩阵型暴露因果效应估计中的加权欧氏平衡

In many scientific fields such as biology, psychology and sociology, there is an increasing interest in estimating the causal effect of a matrix exposure on an outcome. Covariate balancing is crucial in causal inference and both exact balancing and approximate balancing methods have been proposed in the past decades. However, due to the large number of constraints, it is difficult to achieve exact balance or to select the threshold parameters for approximate balancing…

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Counterfactual Copula and Its Application to the Effects of College Education on Intergenerational Mobility

反事实 Copula 及其在大学教育与代际流动研究中的应用

This paper proposes a nonparametric estimator of the counterfactual copula of two outcome variables that would be affected by a policy intervention. The proposed estimator allows policymakers to conduct ex-ante evaluations by comparing the estimated counterfactual and actual copulas as well as their corresponding measures of association. Asymptotic properties of the counterfactual copula estimator are established under regularity conditions. These conditions are also used to…

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Estimation of the Directions for Unknown Parameters in Semiparametric Models

半参数模型中未知参数方向的估计

Semiparametric models are useful in econometrics, social sciences and medicine application. In this paper, a new estimator based on least square methods is proposed to estimate the direction of unknown parameters in semi-parametric models. The proposed estimator is consistent and has asymptotic distribution under mild conditions without the knowledge of the form of link function. Simulations show that the proposed estimator is significantly superior to maximum score…

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Detecting long-range dependence for time-varying linear models

时变线性模型的长程依赖检测

We consider the problem of testing for long-range dependence in time-varying coefficient regression models, where the covariates and errors are locally stationary, allowing complex temporal dynamics and heteroscedasticity. We develop KPSS, R/S, V/S, and K/S-type statistics based on the nonparametric residuals. Under the null hypothesis, the local alternatives as well as the fixed alternatives, we derive the limiting distributions of the test statistics. As the four types of…

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Estimating heterogeneous treatment effects with right-censored data via causal survival forests

利用因果生存森林估计右删失数据中的异质性处理效应

Forest-based methods have recently gained in popularity for non-parametric treatment effect estimation. Building on this line of work, we introduce causal survival forests, which can be used to estimate heterogeneous treatment effects in a survival and observational setting where outcomes may be right-censored. Our approach relies on orthogonal estimating equations to robustly adjust for both censoring and selection effects under unconfoundedness. In our experiments, we find…

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Nonparametric Conditional Local Independence Testing

非参数条件局部独立性检验

Conditional local independence is an asymmetric independence relation among continuous time stochastic processes. It describes whether the evolution of one process is directly influenced by another process given the histories of additional processes, and it is important for the description and learning of causal relations among processes. We develop a model-free framework for testing the hypothesis that a counting process is conditionally locally independent of another…

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Local Gaussian process extrapolation for BART models with applications to causal inference

BART 模型的局部高斯过程外推及因果推断应用

Bayesian additive regression trees (BART) is a semi-parametric regression model offering state-of-the-art performance on out-of-sample prediction. Despite this success, standard implementations of BART typically provide inaccurate prediction and overly narrow prediction intervals at points outside the range of the training data. This paper proposes a novel extrapolation strategy that grafts Gaussian processes to the leaf nodes in BART for predicting points outside the range…

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Patient stratification in multi-arm trials: a two-stage procedure with Bayesian profile regression

多臂试验中的患者分层:贝叶斯画像回归两阶段方法

Precision medicine is an emerging field that takes into account individual heterogeneity to inform better clinical practice. In clinical trials, the evaluation of treatment effect heterogeneity is an important component, and recently, many statistical methods have been proposed for stratifying patients into different subgroups based on such heterogeneity. However, the majority of existing methods developed for this purpose focus on the case with a dichotomous treatment and…

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Estimating High Dimensional Monotone Index Models by Iterative Convex Optimization1

通过迭代凸优化估计高维单调指数模型

In this paper we propose new approaches to estimating large dimensional monotone index models. This class of models has been popular in the applied and theoretical econometrics literatures as it includes discrete choice, nonparametric transformation, and duration models. A main advantage of our approach is computational. For instance, rank estimation procedures such as those proposed in Han (1987) and Cavanagh and Sherman (1998) that optimize a nonsmooth, non convex…

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Contrasting Identifying Assumptions of Average Causal Effects: Robustness and Semiparametric Efficiency

平均因果效应识别假设的比较:稳健性与半参数效率

Semiparametric inference on average causal effects from observational data is based on assumptions yielding identification of the effects. In practice, several distinct identifying assumptions may be plausible; an analyst has to make a delicate choice between these models. In this paper, we study three identifying assumptions based on the potential outcome framework: the back-door assumption, which uses pre-treatment covariates, the front-door assumption, which uses…

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The Lauritzen-Chen Likelihood For Graphical Models

图模型的 Lauritzen–Chen 似然

Graphical models such as Markov random fields (MRFs) that are associated with undirected graphs, and Bayesian networks (BNs) that are associated with directed acyclic graphs, have proven to be a very popular approach for reasoning under uncertainty, prediction problems and causal inference. Parametric MRF likelihoods are well-studied for Gaussian and categorical data. However, in more complicated parametric and semi-parametric settings, likelihoods specified via clique…

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New $\sqrt{n}$-consistent, numerically stable higher-order influence function estimators

新的根号 n 一致且数值稳定的高阶影响函数估计量

Higher-Order Influence Functions (HOIFs) provide a unified theory for constructing rate-optimal estimators for a large class of low-dimensional (smooth) statistical functionals/parameters (and sometimes even infinite-dimensional functions) that arise in substantive fields including epidemiology, economics, and the social sciences. Since the introduction of HOIFs by Robins et al. (2008), they have been viewed mostly as a theoretical benchmark rather than a useful tool for…

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Inference on Individual Treatment Effects in Nonseparable Triangular Models

非可分三角模型中个体处理效应的统计推断

In nonseparable triangular models with a binary endogenous treatment and a binary instrumental variable, Vuong and Xu (2017) established identification results for individual treatment effects (ITEs) under the rank invariance assumption. Using their approach, Feng, Vuong, and Xu (2019) proposed a uniformly consistent kernel estimator for the density of the ITE that utilizes estimated ITEs. In this paper, we establish the asymptotic normality of the density estimator of Feng,…

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Nonparametric estimation of multivariate hidden Markov models using tensor-product B-splines

基于张量积 B 样条的多元隐马尔可夫模型非参数估计

For multivariate time series driven by underlying states, hidden Markov models (HMMs) constitute a powerful framework which can be flexibly tailored to the situation at hand. However, in practice it can be challenging to choose an adequate emission distribution for multivariate observation vectors. For example, the marginal data distribution may not immediately reveal the within-state distributional form, and also the different data streams may operate on different supports,…

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Deep Neural Networks for Nonparametric Interaction Models with Diverging Dimension

维度增长下非参数交互模型的深度神经网络估计

Deep neural networks have achieved tremendous success due to their representation power and adaptation to low-dimensional structures. Their potential for estimating structured regression functions has been recently established in the literature. However, most of the studies require the input dimension to be fixed and consequently ignore the effect of dimension on the rate of convergence and hamper their applications to modern big data with high dimensionality. In this paper,…

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De-confounding causal inference using latent multiple-mediator pathways

利用潜在多中介路径进行因果去混杂

Causal effect estimation from observational data is one of the essential problems in causal inference. However, most estimation methods rely on the strong assumption that all confounders are observed, which is impractical and untestable in the real world. We develop a mediation analysis framework inferring the latent confounder for debiasing both direct and indirect causal effects. Specifically, we introduce generalized structural equation modeling that incorporates…

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Minimax Instrumental Variable Regression and $L_2$ Convergence Guarantees without Identification or Closedness

无需唯一识别或闭合条件的极小极大工具变量回归及 L₂ 收敛保证

In this paper, we study nonparametric estimation of instrumental variable (IV) regressions. Recently, many flexible machine learning methods have been developed for instrumental variable estimation. However, these methods have at least one of the following limitations: (1) restricting the IV regression to be uniquely identified; (2) only obtaining estimation error rates in terms of pseudometrics (\emph{e.g.,} projected norm) rather than valid metrics (\emph{e.g.,} $L_2$ norm)…

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Time-varying correlation network analysis of non-stationary multivariate time series with complex trends

具有复杂趋势的非平稳多元时间序列时变相关网络分析

This paper proposes a flexible framework for inferring large-scale time-varying and time-lagged correlation networks from multivariate or high-dimensional non-stationary time series with piecewise smooth trends. Built on a novel and unified multiple-testing procedure of time-lagged cross-correlation functions with a fixed or diverging number of lags, our method can accurately disclose flexible time-varying network structures associated with complex functional structures at…

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On semiparametric estimation of the intercept of the sample selection model: a kernel approach

样本选择模型截距的半参数估计:核方法

This paper presents a new perspective on the identification at infinity for the intercept of the sample selection model as identification at the boundary via a transformation of the selection index. This perspective suggests generalizations of estimation at infinity to kernel regression estimation at the boundary and further to local linear estimation at the boundary. The proposed kernel-type estimators with an estimated transformation are proven to be nonparametric-rate…

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Estimating Longitudinal Causal Effects with Unobserved Noncompliance Using a Semi-Parametric G-computation Algorithm

用半参数 G 计算估计依从性不可观测时的纵向因果效应

Participant noncompliance, in which participants do not follow their assigned treatment protocol, often obscures the causal relationship between treatment and treatment effect in randomized trials. In the longitudinal setting, the G-computation algorithm can adjust for confounding to estimate causal effects. Typically, G-computation assumes that both 1) compliance is observed; and 2) the densities of the confounders can be correctly specified. We aim to develop a…

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Estimating Time-Varying Networks for High-Dimensional Time Series

高维时间序列的时变网络估计

We explore time-varying networks for high-dimensional locally stationary time series, using the large VAR model framework with both the transition and (error) precision matrices evolving smoothly over time. Two types of time-varying graphs are investigated: one containing directed edges of Granger causality linkages, and the other containing undirected edges of partial correlation linkages. Under the sparse structural assumption, we propose a penalised local linear method…

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Factorial survival analysis for treatment effects under dependent censoring

依赖删失下治疗效应的析因生存分析

Factorial analyses offer a powerful nonparametric means to detect main or interaction effects among multiple treatments. For survival outcomes, e.g. from clinical trials, such techniques can be adopted for comparing reasonable quantifications of treatment effects. The key difficulty to solve in survival analysis concerns the proper handling of censoring. So far, all existing factorial analyses for survival data were developed under the independent censoring assumption, which…

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Augmented Learning of Heterogeneous Treatment Effects via Gradient Boosting Trees

基于梯度提升树的异质性处理效应增广学习

Heterogeneous treatment effects (HTE) based on patients' genetic or clinical factors are of significant interest to precision medicine. Simultaneously modeling HTE and corresponding main effects for randomized clinical trials with high-dimensional predictive markers is challenging. Motivated by the modified covariates approach, we propose a two-stage statistical learning procedure for estimating HTE with optimal efficiency augmentation, generalizing to arbitrary interaction…

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Nonparametric calibration for stochastic reaction-diffusion equations based on discrete observations

基于离散观测的随机反应扩散方程非参数校准

Nonparametric estimation for semilinear SPDEs, namely stochastic reaction-diffusion equations in one space dimension, is studied. We consider observations of the solution field on a discrete grid in time and space with infill asymptotics in both coordinates. Firstly, we derive a nonparametric estimator for the reaction function of the underlying equation. The estimate is chosen from a finite-dimensional function space based on a least squares criterion. Oracle inequalities…

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