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An Efficient Doubly-Robust Test for the Kernel Treatment Effect

核处理效应的高效双重稳健检验

The average treatment effect, which is the difference in expectation of the counterfactuals, is probably the most popular target effect in causal inference with binary treatments. However, treatments may have effects beyond the mean, for instance decreasing or increasing the variance. We propose a new kernel-based test for distributional effects of the treatment. It is, to the best of our knowledge, the first kernel-based, doubly-robust test with provably valid type-I error.…

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PAM-HC: A Bayesian Nonparametric Construction of Hybrid Control for Randomized Clinical Trials Using External Data

PAM-HC:利用外部数据构建随机临床试验混合对照的贝叶斯非参数方法

It is highly desirable to borrow information from external data to augment a control arm in a randomized clinical trial, especially in settings where the sample size for the control arm is limited. However, a main challenge in borrowing information from external data is to accommodate potential heterogeneous subpopulations across the external and trial data. We apply a Bayesian nonparametric model called Plaid Atoms Model (PAM) to identify overlapping and unique…

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Learning Invariant Representations under General Interventions on the Response

响应变量受到一般干预时的不变表示学习

It has become increasingly common nowadays to collect observations of feature and response pairs from different environments. As a consequence, one has to apply learned predictors to data with a different distribution due to distribution shifts. One principled approach is to adopt the structural causal models to describe training and test models, following the invariance principle which says that the conditional distribution of the response given its predictors remains the…

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Incorporating Prior Knowledge of Latent Group Structure in Panel Data Models

在面板模型中纳入潜在分组结构的先验知识

The assumption of group heterogeneity has become popular in panel data models. We develop a constrained Bayesian grouped estimator that exploits researchers' prior beliefs on groups in a form of pairwise constraints, indicating whether a pair of units is likely to belong to a same group or different groups. We propose a prior to incorporate the pairwise constraints with varying degrees of confidence. The whole framework is built on the nonparametric Bayesian method, which…

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Stochastic Learning of Semiparametric Monotone Index Models with Large Sample Size

超大样本半参数单调指数模型的随机学习

I study the estimation of semiparametric monotone index models in the scenario where the number of observation points $n$ is extremely large and conventional approaches fail to work due to heavy computational burdens. Motivated by the mini-batch gradient descent algorithm (MBGD) that is widely used as a stochastic optimization tool in the machine learning field, I proposes a novel subsample- and iteration-based estimation procedure. In particular, starting from any initial…

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Cross-temporal probabilistic forecast reconciliation: Methodological and practical issues

横截面与时间联合概率预测协调:方法与实践问题

Forecast reconciliation is a post-forecasting process that involves transforming a set of incoherent forecasts into coherent forecasts which satisfy a given set of linear constraints for a multivariate time series. In this paper we extend the current state-of-the-art cross-sectional probabilistic forecast reconciliation approach to encompass a cross-temporal framework, where temporal constraints are also applied. Our proposed methodology employs both parametric Gaussian and…

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Dynamic treatment effect phenotyping through functional survival analysis

通过函数型生存分析刻画动态处理效应类型

In recent years, research interest in personalised treatments has been growing. However, treatment effect heterogeneity and possibly time-varying treatment effects are still often overlooked in clinical studies. Statistical tools are needed for the identification of treatment response patterns, taking into account that treatment response is not constant over time. We aim to provide an innovative method to obtain dynamic treatment effect phenotypes on a time-to-event outcome,…

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A Bootstrap Specification Test for Semiparametric Models with Generated Regressors

含生成回归变量的半参数模型自助法设定检验

This paper provides a specification test for semiparametric models with nonparametrically generated regressors. Such variables are not observed by the researcher but are nonparametrically identified and estimable. Applications of the test include models with endogenous regressors identified by control functions, semiparametric sample selection models, or binary games with incomplete information. The statistic is built from the residuals of the semiparametric model. A novel…

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Encompassing Tests for Nonparametric Regressions

非参数回归的涵盖检验

We set up a formal framework to characterize encompassing of nonparametric models through the L2 distance. We contrast it to previous literature on the comparison of nonparametric regression models. We then develop testing procedures for the encompassing hypothesis that are fully nonparametric. Our test statistics depend on kernel regression, raising the issue of bandwidth's choice. We investigate two alternative approaches to obtain a "small bias property" for our test…

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Partly Linear Instrumental Variables Regressions without Smoothing on the Instruments

无需对工具变量平滑的部分线性工具变量回归

We consider a semiparametric partly linear model identified by instrumental variables. We propose an estimation method that does not smooth on the instruments and we extend the Landweber-Fridman regularization scheme to the estimation of this semiparametric model. We then show the asymptotic normality of the parametric estimator and obtain the convergence rate for the nonparametric estimator. Our estimator that does not smooth on the instruments coincides with a typical…

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Causal Inference with Noncompliance and Unknown Interference

不依从与未知干扰下的因果推断

We consider a causal inference model in which individuals interact in a social network and they may not comply with the assigned treatments. In particular, we suppose that the form of network interference is unknown to researchers. To estimate meaningful causal parameters in this situation, we introduce a new concept of exposure mapping, which summarizes potentially complicated spillover effects into a fixed dimensional statistic of instrumental variables. We investigate…

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causalBETA: An R Package for Bayesian Semiparametric Causal Inference with Event-Time Outcomes

causalBETA:事件时间结局的贝叶斯半参数因果推断 R 包

Observational studies are often conducted to estimate causal effects of treatments or exposures on event-time outcomes. Since treatments are not randomized in observational studies, techniques from causal inference are required to adjust for confounding. Bayesian approaches to causal estimates are desirable because they provide 1) prior smoothing provides useful regularization of causal effect estimates, 2) flexible models that are robust to misspecification, 3) full…

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Conservative Inference for Counterfactuals

反事实的保守推断

In causal inference, the joint law of a set of counterfactual random variables is generally not identified. We show that a conservative version of the joint law - corresponding to the smallest treatment effect - is identified. Finding this law uses recent results from optimal transport theory. Under this conservative law we can bound causal effects and we may construct inferences for each individual's counterfactual dose-response curve. Intuitively, this is the flattest…

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Covariate Adjustment in Experiments with Matched Pairs

配对随机实验中的协变量调整

This paper studies inference on the average treatment effect in experiments in which treatment status is determined according to "matched pairs" and it is additionally desired to adjust for observed, baseline covariates to gain further precision. By a "matched pairs" design, we mean that units are sampled i.i.d. from the population of interest, paired according to observed, baseline covariates and finally, within each pair, one unit is selected at random for treatment.…

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Machine Learning for Staggered Difference-in-Differences and Dynamic Treatment Effect Heterogeneity

错位实施双重差分中的机器学习与动态处理效应异质性

We combine two recently proposed nonparametric difference-in-differences methods, extending them to enable the examination of treatment effect heterogeneity in the staggered adoption setting using machine learning. The proposed method, machine learning difference-in-differences (MLDID), allows for estimation of time-varying conditional average treatment effects on the treated, which can be used to conduct detailed inference on drivers of treatment effect heterogeneity. We…

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Partial identification for discrete data with nonignorable missing outcomes

结局非可忽略缺失下离散数据的部分识别

Nonignorable missing outcomes are common in real world datasets and often require strong parametric assumptions to achieve identification. These assumptions can be implausible or untestable, and so we may forgo them in favour of partially identified models that narrow the set of a priori possible values to an identification region. Here we propose a new nonparametric Bayes method that allows for the incorporation of multiple clinically relevant restrictions of the parameter…

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Locally Private Causal Inference for Randomized Experiments

随机实验中局部差分隐私数据的因果推断

Local differential privacy is a differential privacy paradigm in which individuals first apply a privacy mechanism to their data (often by adding noise) before transmitting the result to a curator. The noise for privacy results in additional bias and variance in their analyses. Thus it is of great importance for analysts to incorporate the privacy noise into valid inference. In this article, we develop methodologies to infer causal effects from locally privatized data under…

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A Semiparametric Instrumented Difference-in-Differences Approach to Policy Learning

用于政策学习的半参数工具变量双重差分方法

Recently, there has been a surge in methodological development for the difference-in-differences (DiD) approach to evaluate causal effects. Standard methods in the literature rely on the parallel trends assumption to identify the average treatment effect on the treated. However, the parallel trends assumption may be violated in the presence of unmeasured confounding, and the average treatment effect on the treated may not be useful in learning a treatment assignment policy…

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Uniform Inference for Kernel Density Estimators with Dyadic Data

成对关系数据核密度估计的一致推断

Dyadic data is often encountered when quantities of interest are associated with the edges of a network. As such it plays an important role in statistics, econometrics and many other data science disciplines. We consider the problem of uniformly estimating a dyadic Lebesgue density function, focusing on nonparametric kernel-based estimators taking the form of dyadic empirical processes. Our main contributions include the minimax-optimal uniform convergence rate of the dyadic…

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Factor Augmented Sparse Throughput Deep ReLU Neural Networks for High Dimensional Regression

用于高维回归的因子增强稀疏直通深度 ReLU 神经网络

This paper introduces a Factor Augmented Sparse Throughput (FAST) model that utilizes both latent factors and sparse idiosyncratic components for nonparametric regression. The FAST model bridges factor models on one end and sparse nonparametric models on the other end. It encompasses structured nonparametric models such as factor augmented additive models and sparse low-dimensional nonparametric interaction models and covers the cases where the covariates do not admit factor…

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G-formula for causal inference via multiple imputation

通过多重插补实现因果推断中的 G 公式

G-formula is a popular approach for estimating treatment or exposure effects from longitudinal data that are subject to time-varying confounding. G-formula estimation is typically performed by Monte-Carlo simulation, with non-parametric bootstrapping used for inference. We show that G-formula can be implemented by exploiting existing methods for multiple imputation (MI) for synthetic data. This involves using an existing modified version of Rubin's variance estimator. In…

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Positivity-free Policy Learning with Observational Data

无需正值性假设的观察数据政策学习

Policy learning utilizing observational data is pivotal across various domains, with the objective of learning the optimal treatment assignment policy while adhering to specific constraints such as fairness, budget, and simplicity. This study introduces a novel positivity-free (stochastic) policy learning framework designed to address the challenges posed by the impracticality of the positivity assumption in real-world scenarios. This framework leverages incremental…

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A neutral comparison of statistical methods for time-to-event analyses under non-proportional hazards

非比例风险下生存分析统计方法的中立比较

While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best inferential approach under non-proportional hazards (NPH). However, a wide range of parametric and non-parametric methods for testing and estimation in this scenario have been proposed. To provide recommendations on the statistical analysis of clinical trials where non proportional hazards are expected, we conducted a…

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Identification and Estimation in a Class of Potential Outcomes Models

一类潜在结果模型的识别与估计

This paper develops a class of potential outcomes models characterized by three main features: (i) Unobserved heterogeneity can be represented by a vector of potential outcomes and a type describing the manner in which an instrument determines the choice of treatment; (ii) The availability of an instrumental variable that is conditionally independent of unobserved heterogeneity; and (iii) The imposition of convex restrictions on the distribution of unobserved heterogeneity.…

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