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Extrapolation of Relative Treatment Effects using Change-point Survival Models

利用变点生存模型外推相对治疗效应

Introduction: Modelling of relative treatment effects is an important aspect to consider when extrapolating the long-term survival outcomes of treatments. Flexible parametric models offer the ability to accurately model the observed data, however, the extrapolated relative treatment effects and subsequent survival function may lack face validity. Methods: We investigate the ability of change-point survival models to estimate changes in the relative treatment effects,…

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Unconditional Quantile Partial Effects via Conditional Quantile Regression

通过条件分位数回归估计无条件分位数偏效应

This paper develops a semi-parametric procedure for estimation of unconditional quantile partial effects using quantile regression coefficients. The estimator is based on an identification result showing that, for continuous covariates, unconditional quantile effects are a weighted average of conditional ones at particular quantile levels that depend on the covariates. We propose a two-step estimator for the unconditional effects where in the first step one estimates a…

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LRD spectral analysis of multifractional functional time series on manifolds

流形上多分数阶函数型时间序列的长程依赖谱分析

This paper addresses the estimation of the second-order structure of a manifold cross-time random field (RF) displaying spatially varying Long Range Dependence (LRD), adopting the functional time series framework introduced in Ruiz-Medina (2022). Conditions for the asymptotic unbiasedness of the integrated periodogram operator in the Hilbert-Schmidt operator norm are derived beyond structural assumptions. Weak-consistent estimation of the long-memory operator is achieved…

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Modeling Systemic Risk: A Time-Varying Nonparametric Causal Inference Framework

系统性风险建模:时变非参数因果推断框架

We propose a nonparametric and time-varying directed information graph (TV-DIG) framework to estimate the evolving causal structure in time series networks, thereby addressing the limitations of traditional econometric models in capturing high-dimensional, nonlinear, and time-varying interconnections among series. This framework employs an information-theoretic measure rooted in a generalized version of Granger-causality, which is applicable to both linear and nonlinear…

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Minimax Analysis for Inverse Risk in Nonparametric Planer Invertible Regression

非参数平面可逆回归中逆函数风险的极小极大分析

We study a minimax risk of estimating inverse functions on a plane, while keeping an estimator is also invertible. Learning invertibility from data and exploiting an invertible estimator are used in many domains, such as statistics, econometrics, and machine learning. Although the consistency and universality of invertible estimators have been well investigated, analysis of the efficiency of these methods is still under development. In this study, we study a minimax risk for…

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Causal Discovery from Subsampled Time Series with Proxy Variables

利用代理变量从低频采样时间序列发现因果结构

Inferring causal structures from time series data is the central interest of many scientific inquiries. A major barrier to such inference is the problem of subsampling, i.e., the frequency of measurement is much lower than that of causal influence. To overcome this problem, numerous methods have been proposed, yet either was limited to the linear case or failed to achieve identifiability. In this paper, we propose a constraint-based algorithm that can identify the entire…

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Minimax rates for heterogeneous causal effect estimation

异质性因果效应估计的极小极大收敛速率

Estimation of heterogeneous causal effects - i.e., how effects of policies and treatments vary across subjects - is a fundamental task in causal inference. Many methods for estimating conditional average treatment effects (CATEs) have been proposed in recent years, but questions surrounding optimality have remained largely unanswered. In particular, a minimax theory of optimality has yet to be developed, with the minimax rate of convergence and construction of rate-optimal…

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Causal effects of intervening variables in settings with unmeasured confounding

存在未测混杂时中间变量的因果效应

We present new results on average causal effects in settings with unmeasured exposure-outcome confounding. Our results are motivated by a class of estimands, e.g., frequently of interest in medicine and public health, that are currently not targeted by standard approaches for average causal effects. We recognize these estimands as queries about the average causal effect of an intervening variable. We anchor our introduction of these estimands in an investigation of the role…

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Fair and Robust Estimation of Heterogeneous Treatment Effects for Policy Learning

面向政策学习的公平且稳健的异质处理效应估计

We propose a simple and general framework for nonparametric estimation of heterogeneous treatment effects under fairness constraints. Under standard regularity conditions, we show that the resulting estimators possess the double robustness property. We use this framework to characterize the trade-off between fairness and the maximum welfare achievable by the optimal policy. We evaluate the methods in a simulation study and illustrate them in a real-world case study.

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Distribution Regression with Sample Selection, with an Application to Wage Decompositions in the UK

内生样本选择下的分布回归及英国工资分解

We develop a distribution regression model under endogenous sample selection. This model is a semi-parametric generalization of the Heckman selection model. It accommodates much richer effects of the covariates on outcome distribution and patterns of heterogeneity in the selection process, and allows for drastic departures from the Gaussian error structure, while maintaining the same level tractability as the classical model. The model applies to continuous, discrete and…

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Predicting Financial Literacy via Semi-supervised Learning

用半监督学习预测金融素养

Financial literacy (FL) represents a person's ability to turn assets into income, and understanding digital currencies has been added to the modern definition. FL can be predicted by exploiting unlabelled recorded data in financial networks via semi-supervised learning (SSL). Measuring and predicting FL has not been widely studied, resulting in limited understanding of customer financial engagement consequences. Previous studies have shown that low FL increases the risk of…

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Boundary Adaptive Local Polynomial Conditional Density Estimators

边界自适应的局部多项式条件密度估计

We begin by introducing a class of conditional density estimators based on local polynomial techniques. The estimators are boundary adaptive and easy to implement. We then study the (pointwise and) uniform statistical properties of the estimators, offering characterizations of both probability concentration and distributional approximation. In particular, we establish uniform convergence rates in probability and valid Gaussian distributional approximations for the…

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Uncertainty Quantification in Heterogeneous Treatment Effect Estimation with Gaussian-Process-Based Partially Linear Model

基于高斯过程部分线性模型的异质性处理效应不确定性量化

Estimating heterogeneous treatment effects across individuals has attracted growing attention as a statistical tool for performing critical decision-making. We propose a Bayesian inference framework that quantifies the uncertainty in treatment effect estimation to support decision-making in a relatively small sample size setting. Our proposed model places Gaussian process priors on the nonparametric components of a semiparametric model called a partially linear model. This…

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Debiased inference for a covariate-adjusted regression function

协变量调整回归函数的去偏推断

In this article, we study nonparametric inference for a covariate-adjusted regression function. This parameter captures the average association between a continuous exposure and an outcome after adjusting for other covariates. In particular, under certain causal conditions, this parameter corresponds to the average outcome had all units been assigned to a specific exposure level, known as the causal dose-response curve. We propose a debiased local linear estimator of the…

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Inferring Causality from Time Series data based on Structural Causal Model and its application to Neural Connectomics

基于结构因果模型的时间序列因果推断及其神经连接组应用

Inferring causation from time series data is of scientific interest in different disciplines, particularly in neural connectomics. While different approaches exist in the literature with parametric modeling assumptions, we focus on a non-parametric model for time series satisfying a Markovian structural causal model with stationary distribution and without concurrent effects. We show that the model structure can be used to its advantage to obtain an elegant algorithm for…

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Inference on Optimal Dynamic Policies via Softmax Approximation

通过 Softmax 近似对最优动态政策进行推断

Estimating optimal dynamic policies from offline data is a fundamental problem in dynamic decision making. In the context of causal inference, the problem is known as estimating the optimal dynamic treatment regime. Even though there exists a plethora of methods for estimation, constructing confidence intervals for the value of the optimal regime and structural parameters associated with it is inherently harder, as it involves non-linear and non-differentiable functionals of…

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Multiply robust estimators in longitudinal studies with missing data under control-based imputation

基于对照组插补的纵向缺失数据多重稳健估计

Longitudinal studies are often subject to missing data. The ICH E9(R1) addendum addresses the importance of defining a treatment effect estimand with the consideration of intercurrent events. Jump-to-reference (J2R) is one classically envisioned control-based scenario for the treatment effect evaluation using the hypothetical strategy, where the participants in the treatment group after intercurrent events are assumed to have the same disease progress as those with identical…

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Linking convolutional kernel size to generalization bias in face analysis CNNs

卷积核大小与人脸分析 CNN 泛化偏差的联系

Training dataset biases are by far the most scrutinized factors when explaining algorithmic biases of neural networks. In contrast, hyperparameters related to the neural network architecture have largely been ignored even though different network parameterizations are known to induce different implicit biases over learned features. For example, convolutional kernel size is known to affect the frequency content of features learned in CNNs. In this work, we present a causal…

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A unified framework for covariate adjustment under stratified randomization

分层随机化下协变量调整的统一框架

Randomization, as a key technique in clinical trials, can eliminate sources of bias and produce comparable treatment groups. In randomized experiments, the treatment effect is a parameter of general interest. Researchers have explored the validity of using linear models to estimate the treatment effect and perform covariate adjustment and thus improve the estimation efficiency. However, the relationship between covariates and outcomes is not necessarily linear, and is often…

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Identification in Endogenous Sequential Treatment Regimes

内生序贯处理方案中的识别

This paper develops a novel nonparametric identification method for treatment effects in settings where individuals self-select into treatment sequences. I propose an identification strategy which relies on a dynamic version of standard Instrumental Variables (IV) assumptions and builds on a dynamic version of the Marginal Treatment Effects (MTE) as the fundamental building block for treatment effects. The main contribution of the paper is to relax assumptions on the support…

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On Quantile Treatment Effects, Rank Similarity, and Variation of Instrumental Variables

分位数处理效应、秩相似性与工具变量变异

This paper investigates how certain relationship between observed and counterfactual distributions serves as an identifying condition for treatment effects when the treatment is endogenous, and shows that this condition holds in a range of nonparametric models for treatment effects. To this end, we first provide a novel characterization of the prevalent assumption restricting treatment heterogeneity in the literature, namely rank similarity. Our characterization demonstrates…

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Conditional-mean Multiplicative Operator Models for Count Time Series

计数时间序列的条件均值乘法算子模型

Multiplicative error models (MEMs) are commonly used for real-valued time series, but they cannot be applied to discrete-valued count time series as the involved multiplication would not preserve the integer nature of the data. Thus, the concept of a multiplicative operator for counts is proposed (as well as several specific instances thereof), which are then used to develop a kind of MEMs for count time series (CMEMs). If equipped with a linear conditional mean, the…

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A Sparse Factor Model for Clustering High-Dimensional Longitudinal Data

用于高维纵向数据聚类的稀疏因子模型

Recent advances in engineering technologies have enabled the collection of a large number of longitudinal features. This wealth of information presents unique opportunities for researchers to investigate the complex nature of diseases and uncover underlying disease mechanisms. However, analyzing such kind of data can be difficult due to its high dimensionality, heterogeneity and computational challenges. In this paper, we propose a Bayesian nonparametric mixture model for…

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Partial Identification and Inference for Conditional Distributions of Treatment Effects

条件处理效应分布的部分识别与推断

This paper considers identification and inference for the distribution of treatment effects conditional on observable covariates. Since the conditional distribution of treatment effects is not point identified without strong assumptions, we obtain bounds on the conditional distribution of treatment effects by using the Makarov bounds. We also consider the case where the treatment is endogenous and propose two stochastic dominance assumptions to tighten the bounds. We develop…

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