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Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments

随机实验中通用机器学习发现的异质性处理效应:统计推断

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with many covariates and small sample size. In addition, the quantification of estimation uncertainty remains a challenge. We develop a general approach to statistical inference for heterogeneous treatment effects…

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Graphical criteria for the identification of marginal causal effects in continuous-time survival and event-history analyses

连续时间生存与事件史分析中边际因果效应识别的图准则

We consider continuous-time survival or more general event-history settings, where the aim is to infer the causal effect of a time-dependent treatment process. This is formalised as the effect on the outcome event of a (possibly hypothetical) intervention on the intensity of the treatment process, i.e. a stochastic intervention. To establish whether valid inference about the interventional situation can be drawn from typical observational, i.e. non-experimental, data we…

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Extrapolation and generative algorithms for three applications in finance

外推与生成算法在三个金融问题中的应用

For three applications of central interest in finance, we demonstrate the relevance of numerical algorithms based on reproducing kernel Hilbert space (RKHS) techniques. Three use cases are investigated. First, we show that extrapolating from few pricer examples leads to sufficiently accurate and computationally efficient results so that our algorithm can serve as a pricing framework. The second use case concerns reverse stress testing, which is formulated as an inversion…

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Propensity Score Analysis with Guaranteed Subgroup Balance

保证亚组平衡的倾向得分分析

Estimating the causal treatment effects by subgroups is important in observational studies when the treatment effect heterogeneity may be present. Existing propensity score methods rely on a correctly specified propensity score model. Model misspecification results in biased treatment effect estimation and covariate imbalance. We proposed a new algorithm, the propensity score analysis with guaranteed subgroup balance (G-SBPS), to achieve covariate mean balance in all…

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Inference under partial identification with minimax test statistics

基于极小极大检验统计量的部分识别推断

We provide a means of computing and estimating the asymptotic distributions of statistics based on an outer minimization of an inner maximization. Such test statistics, which arise frequently in moment models, are of special interest in providing hypothesis tests under partial identification. Under general conditions, we provide an asymptotic characterization of such test statistics using the minimax theorem, and a means of computing critical values using the bootstrap.…

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Optimally weighted average derivative effects

最优加权平均导数效应

Weighted average derivative effects (WADEs) are nonparametric estimands with uses in economics and causal inference. Debiased WADE estimators typically require learning the conditional mean outcome as well as a Riesz representer (RR) that characterises the requisite debiasing corrections. RR estimators for WADEs often rely on kernel estimators, introducing complicated bandwidth-dependant biases. In our work we propose a new class of RRs that are isomorphic to the class of…

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Context-dependent Causality (the Non-Nonotonic Case)

情境依赖的因果关系:非单调情形

We develop a novel identification strategy as well as a new estimator for context-dependent causal inference in non-parametric triangular models with non-separable disturbances. Departing from the common practice, our analysis does not rely on the strict monotonicity assumption. Our key contribution lies in leveraging on diffusion models to formulate the structural equations as a system evolving from noise accumulation to account for the influence of the latent context…

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Principal Stratification with Continuous Post-Treatment Variables: Nonparametric Identification and Semiparametric Estimation

连续处理后变量的主层分层:非参数识别与半参数估计

Post-treatment variables often complicate causal inference. They appear in many scientific problems, including noncompliance, truncation by death, mediation, and surrogate endpoint evaluation. Principal stratification is a strategy to address these challenges by adjusting for the potential values of the post-treatment variables, defined as the principal strata. It allows for characterizing treatment effect heterogeneity across principal strata and unveiling the mechanism of…

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Semi-parametric TEnsor Factor Analysis by Iteratively Projected Singular Value Decomposition

基于迭代投影奇异值分解的半参数张量因子分析

This paper introduces a general framework of Semi-parametric TEnsor Factor Analysis (STEFA) that focuses on the methodology and theory of low-rank tensor decomposition with auxiliary covariates. Semi-parametric TEnsor Factor Analysis models extend tensor factor models by incorporating auxiliary covariates in the loading matrices. We propose an algorithm of iteratively projected singular value decomposition (IP-SVD) for the semi-parametric estimation. It iteratively projects…

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Time-Varying Matrix Factor Models

时变矩阵因子模型

Matrix-variate data of high dimensions are frequently observed in finance and economics, spanning extended time periods, such as the long-term data on international trade flows among numerous countries. To address potential structural shifts and explore the matrix structure's informational context, we propose a time-varying matrix factor model. This model accommodates changing factor loadings over time, revealing the underlying dynamic structure through nonparametric…

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Improving the Estimation of Site-Specific Effects and their Distribution in Multisite Trials

改进多地点试验中地点特定效应及其分布的估计

In multisite trials, researchers are often interested in several inferential goals: estimating treatment effects for each site, ranking these effects, and studying their distribution. This study seeks to identify optimal methods for estimating these targets. Through a comprehensive simulation study, we assess two strategies and their combined effects: semiparametric modeling of the prior distribution, and alternative posterior summary methods tailored to minimize specific…

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C-XGBoost: A tree boosting model for causal effect estimation

C-XGBoost:用于因果效应估计的树提升模型

Causal effect estimation aims at estimating the Average Treatment Effect as well as the Conditional Average Treatment Effect of a treatment to an outcome from the available data. This knowledge is important in many safety-critical domains, where it often needs to be extracted from observational data. In this work, we propose a new causal inference model, named C-XGBoost, for the prediction of potential outcomes. The motivation of our approach is to exploit the superiority of…

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"Sound and Fury": Nonlinear Functionals of Volatility Matrix in the Presence of Jump and Noise

“喧哗与骚动”:跳跃与噪声下波动率矩阵非线性泛函的推断

This paper resolves a pivotal open problem on nonparametric inference for nonlinear functionals of volatility matrix. Multiple prominent statistical tasks can be formulated as functionals of volatility matrix, yet a unified statistical theory of general nonlinear functionals based on noisy data remains challenging and elusive. Nonetheless, this paper shows it can be achieved by combining the strengths of pre-averaging, jump truncation and nonlinearity bias correction. In…

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Sensitivity analysis for principal ignorability violation in estimating complier and noncomplier average causal effects

依从者与不依从者平均因果效应中主层可忽略性违反的敏感性分析

An important strategy for identifying principal causal effects, which are often used in settings with noncompliance, is to invoke the principal ignorability (PI) assumption. As PI is untestable, it is important to gauge how sensitive effect estimates are to its violation. We focus on this task for the common one-sided noncompliance setting where there are two principal strata, compliers and noncompliers. Under PI, compliers and noncompliers share the same…

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Deconvolution from two order statistics

基于两个次序统计量的反卷积

Economic data are often contaminated by measurement errors and truncated by ranking. This paper shows that the classical measurement error model with independent and additive measurement errors is identified nonparametrically using only two order statistics of repeated measurements. The identification result confirms a hypothesis by Athey and Haile (2002) for a symmetric ascending auction model with unobserved heterogeneity. Extensions allow for heterogeneous measurement…

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A General Form of Covariate Adjustment in Randomized Clinical Trials

随机临床试验中协变量调整的一般形式

In randomized clinical trials, adjusting for baseline covariates can improve credibility and efficiency for demonstrating and quantifying treatment effects. This article studies the augmented inverse propensity weighted (AIPW) estimator, which is a general form of covariate adjustment that uses linear, generalized linear, and non-parametric or machine learning models for the conditional mean of the response given covariates. Under covariate-adaptive randomization, we…

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Resistant Inference in Instrumental Variable Models

工具变量模型中的抗污染推断

The classical tests in the instrumental variable model can behave arbitrarily if the data is contaminated. For instance, one outlying observation can be enough to change the outcome of a test. We develop a framework to construct testing procedures that are robust to weak instruments, outliers and heavy-tailed errors in the instrumental variable model. The framework is constructed upon M-estimators. By deriving the influence functions of the classical weak instrument robust…

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Single Proxy Control

单代理混杂控制

Negative control variables are sometimes used in non-experimental studies to detect the presence of confounding by hidden factors. A negative control outcome (NCO) is an outcome that is influenced by unobserved confounders of the exposure effects on the outcome in view, but is not causally impacted by the exposure. Tchetgen Tchetgen (2013) introduced the Control Outcome Calibration Approach (COCA) as a formal NCO counterfactual method to detect and correct for residual…

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Forster-Warmuth Counterfactual Regression: A Unified Learning Approach

Forster–Warmuth 反事实回归:统一学习方法

Series or orthogonal basis regression is one of the most popular non-parametric regression techniques in practice, obtained by regressing the response on features generated by evaluating the basis functions at observed covariate values. The most routinely used series estimator is based on ordinary least squares fitting, which is known to be minimax rate optimal in various settings, albeit under stringent restrictions on the basis functions and the distribution of covariates.…

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Adaptive estimation for Weakly Dependent Functional Times Series

弱依赖函数型时间序列的自适应估计

The local regularity of functional time series is studied under $L^p-m-$appro\-ximability assumptions. The sample paths are observed with error at possibly random design points. Non-asymptotic concentration bounds of the regularity estimators are derived. As an application, we build nonparametric mean and autocovariance functions estimators that adapt to the regularity and the design, which can be sparse or dense. We also derive the asymptotic normality of the mean…

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Bayesian Nonparametric Trees for Principal Causal Effects

用于主分层因果效应的贝叶斯非参数树模型

Principal stratification analysis evaluates how causal effects of a treatment on a primary outcome vary across strata of units defined by their treatment effect on some intermediate quantity. This endeavor is substantially challenged when the intermediate variable is continuously scaled and there are infinitely many basic principal strata. We employ a Bayesian nonparametric approach to flexibly evaluate treatment effects across flexibly-modeled principal strata. The approach…

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Nonparametric Identification and Estimation with Non-Classical Errors-in-Variables

非经典变量测量误差下的非参数识别与估计

This paper considers nonparametric identification and estimation of the regression function when a covariate is mismeasured. The measurement error need not be classical. Employing the small measurement error approximation, we establish nonparametric identification under weak and easy-to-interpret conditions on the instrumental variable. The paper also provides nonparametric estimators of the regression function and derives their rates of convergence.

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Survey calibration for causal inference: a simple method to balance covariate distributions

用于因果推断的调查校准:协变量分布平衡的简便方法

This paper proposes a~simple, yet powerful, method for balancing distributions of covariates for causal inference based on observational studies. The method makes it possible to balance an arbitrary number of quantiles (e.g., medians, quartiles, or deciles) together with means if necessary. The proposed approach is based on the theory of calibration estimators (Deville and Särndal 1992), in particular, calibration estimators for quantiles, proposed by Harms and Duchesne…

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Incorporating nonparametric methods for estimating causal excursion effects in mobile health with zero-inflated count outcomes

移动健康零膨胀计数结果的因果偏离效应:非参数估计方法

In mobile health, tailoring interventions for real-time delivery is of paramount importance. Micro-randomized trials have emerged as the "gold-standard" methodology for developing such interventions. Analyzing data from these trials provides insights into the efficacy of interventions and the potential moderation by specific covariates. The "causal excursion effect", a novel class of causal estimand, addresses these inquiries. Yet, existing research mainly focuses on…

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