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Root-n consistent semiparametric learning with high-dimensional nuisance functions under minimal sparsity

最小稀疏性下含高维干扰函数的根号样本量一致半参数学习

Treatment effect estimation under unconfoundedness is a fundamental task in causal inference. In response to the challenge of analyzing high-dimensional datasets collected in substantive fields such as epidemiology, genetics, economics, and social sciences, various methods for treatment effect estimation with high-dimensional nuisance parameters (the outcome regression and the propensity score) have been developed in recent years. However, it is still unclear what is the…

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Factors in Fashion: Factor Analysis towards the Mode

众数因子分析:面向条件众数的高维降维方法

The modal factor model represents a new factor model for dimension reduction in high dimensional panel data. Unlike the approximate factor model that targets for the mean factors, it captures factors that influence the conditional mode of the distribution of the observables. Statistical inference is developed with the aid of mode estimation, where the modal factors and the loadings are estimated through maximizing a kernel-type objective function. An easy-to-implement…

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Propensity Score Augmentation in Matching-based Estimation of Causal Effects

匹配式因果效应估计中的倾向得分增广

When assessing the causal effect of a binary exposure using observational data, confounder imbalance across exposure arms must be addressed. Matching methods, including propensity score-based matching, can be used to deconfound the causal relationship of interest. They have been particularly popular in practice, at least in part due to their simplicity and interpretability. However, these methods can suffer from low statistical efficiency compared to many competing methods.…

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Non-parametric efficient estimation of marginal structural models with multi-valued time-varying treatments

多值时变处理下边际结构模型的非参数有效估计

Marginal structural models are a popular method for estimating causal effects in the presence of time-varying exposures. In spite of their popularity, no scalable non-parametric estimator exist for marginal structural models with multi-valued and time-varying treatments. In this paper, we use machine learning together with recent developments in semiparametric efficiency theory for longitudinal studies to propose such an estimator. The proposed estimator is based on a study…

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The mosaic permutation test: an exact and nonparametric goodness-of-fit test for factor models

马赛克置换检验:因子模型的精确非参数拟合优度检验

Financial firms often rely on fundamental factor models to explain correlations among asset returns and manage risk. Yet after major events, e.g., COVID-19, analysts may reassess whether existing risk models continue to fit well: specifically, after accounting for a set of known factor exposures, are the residuals of the asset returns independent? With this motivation, we introduce the mosaic permutation test, a nonparametric goodness-of-fit test for preexisting factor…

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Gaussian Processes for Time Series with Lead-Lag Effects with applications to biology data

具有领先—滞后效应的时间序列高斯过程及其生物数据应用

Investigating the relationship, particularly the lead-lag effect, between time series is a common question across various disciplines, especially when uncovering biological process. However, analyzing time series presents several challenges. Firstly, due to technical reasons, the time points at which observations are made are not at uniform inintervals. Secondly, some lead-lag effects are transient, necessitating time-lag estimation based on a limited number of time points.…

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Gaussian Processes for Observational Dose-Response Inference

用于观察性剂量—反应推断的高斯过程

We adapt Gaussian processes for estimating the average dose-response function in observational settings, introducing a powerful complement to treatment effect estimation for understanding heterogeneous effects. We incorporate samples from a Gaussian process posterior for the propensity score into a Gaussian process response model using Girard's approach to integrating over uncertainty in training data. We show Girard's method admits a positive-definite kernel, and provide…

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Asymptotic considerations in a Bayesian linear model with nonparametrically modelled time series innovations

创新项时间序列非参数建模下贝叶斯线性模型的渐近分析

This paper considers a semiparametric approach within the general Bayesian linear model where the innovations consist of a stationary, mean zero Gaussian time series. While a parametric prior is specified for the linear model coefficients, the autocovariance structure of the time series is modeled nonparametrically using a Bernstein-Gamma process prior for the spectral density function, the Fourier transform of the autocovariance function. When updating this joint prior with…

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An Autoregressive Model for Time Series of Random Objects

随机对象时间序列的自回归模型

Random variables in metric spaces indexed by time and observed at equally spaced time points are receiving increased attention due to their broad applicability. The absence of inherent structure in metric spaces has resulted in a literature that is predominantly non-parametric and model-free. To address this gap in models for time series of random objects, we introduce an adaptation of the classical linear autoregressive model tailored for data lying in a Hadamard space. The…

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Counterfactual Slopes and Their Applications in Social Stratification

反事实斜率及其在社会分层研究中的应用

This paper addresses two prominent theses in social stratification research, the great equalizer thesis and Mare's (1980) school transition thesis. Both theses describe the role of an intermediate educational transition in the association between socioeconomic status and an outcome variable. However, the descriptive regularities of the two theses may be driven by differential selection into the intermediate transition, which prevents the two theses from having substantive…

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Graphical tools for detection and control of selection bias with multiple exposures and samples

多暴露与多样本情形下检测和控制选择偏差的图工具

Among recent developments in definitions and analysis of selection bias is the potential outcomes approach of Kenah (Epidemiology, 2023), which allows non-parametric analysis using single-world intervention graphs, linking selection of study participants to identification of causal effects. Mohan & Pearl (JASA, 2021) provide a framework for missing data via directed acyclic graphs augmented with nodes indicating missingness for each sometimes-missing variable, which allows…

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Non-parametric Replication of Instrumental Variable Estimates Across Studies

跨研究工具变量估计的非参数复现

Replicating causal estimates across different cohorts is crucial for increasing the integrity of epidemiological studies. However, strong assumptions regarding unmeasured confounding and effect modification often hinder this goal. By employing an instrumental variable (IV) approach and targeting the local average treatment effect (LATE), these assumptions can be relaxed to some degree; however, little work has addressed the replicability of IV estimates. In this paper, we…

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Simple robust two-stage estimation and inference for generalized impulse responses and multi-horizon causality

广义脉冲响应与多期因果关系的简便稳健两阶段估计与推断

This paper introduces a novel two-stage estimation and inference procedure for generalized impulse responses (GIRs). GIRs encompass all coefficients in a multi-horizon linear projection model of future outcomes of y on lagged values (Dufour and Renault, 1998), which include the Sims' impulse response. The conventional use of Least Squares (LS) with heteroskedasticity- and autocorrelation-consistent covariance estimation is less precise and often results in unreliable finite…

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On the Comparative Analysis of Average Treatment Effects Estimation via Data Combination

数据组合下平均处理效应估计的比较分析

There is growing interest in exploring causal effects in target populations via data combination. However, most approaches are tailored to specific settings and lack comprehensive comparative analyses. In this article, we focus on a typical scenario involving a source dataset and a target dataset. We first design six settings under covariate shift and conduct a comparative analysis by deriving the semiparametric efficiency bounds for the ATE in the target population. We then…

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Theory of Low Frequency Contamination from Nonstationarity and Misspecification: Consequences for HAR Inference

非平稳与误设造成的低频污染:对异方差与自相关稳健推断的影响

We establish theoretical results about the low frequency contamination (i.e., long memory effects) induced by general nonstationarity for estimates such as the sample autocovariance and the periodogram, and deduce consequences for heteroskedasticity and autocorrelation robust (HAR) inference. We present explicit expressions for the asymptotic bias of these estimates. We distinguish cases where this contamination only occurs as a small-sample problem and cases where the…

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Group Sequential Testing of a Treatment Effect Using a Surrogate Marker

利用替代指标对处理效应进行群序贯检验

The identification of surrogate markers is motivated by their potential to make decisions sooner about a treatment effect. However, few methods have been developed to actually use a surrogate marker to test for a treatment effect in a future study. Most existing methods consider combining surrogate marker and primary outcome information to test for a treatment effect, rely on fully parametric methods where strict parametric assumptions are made about the relationship between…

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Joint spatial modeling of mean and non-homogeneous variance combining semiparametric SAR and GAMLSS models for hedonic prices

结合半参数 SAR 与 GAMLSS 的特征价格均值和异质方差空间建模

In the context of spatial econometrics, it is very useful to have methodologies that allow modeling the spatial dependence of the observed variables and obtaining more precise predictions of both the mean and the variability of the response variable, something very useful in territorial planning and public policies. This paper proposes a new methodology that jointly models the mean and the variance. Also, it allows to model the spatial dependence of the dependent variable as…

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Randomized Spline Trees for Functional Data Classification: Theory and Application to Environmental Time Series

函数型数据分类的随机样条树:理论与环境时间序列应用

Functional data analysis (FDA) and ensemble learning can be powerful tools for analyzing complex environmental time series. Recent literature has highlighted the key role of diversity in enhancing accuracy and reducing variance in ensemble methods.This paper introduces Randomized Spline Trees (RST), a novel algorithm that bridges these two approaches by incorporating randomized functional representations into the Random Forest framework. RST generates diverse functional…

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Identification and multiply robust estimation in causal mediation analysis across principal strata

主分层间因果中介分析的识别与多重稳健估计

We consider assessing causal mediation in the presence of a post-treatment event (examples include noncompliance, a clinical event, or death). We identify natural mediation effects for the entire study population and for each principal stratum characterized by the joint potential values of the post-treatment event. We derive the efficient influence function for each mediation estimand, which motivates a set of multiply robust estimators for inference. The multiply robust…

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How to achieve model-robust inference in stepped wedge trials with model-based methods?

如何用模型方法实现阶梯楔形试验的模型稳健推断?

A stepped wedge design is a unidirectional crossover design where clusters are randomized to distinct treatment sequences. While model-based analysis of stepped wedge designs is standard practice to evaluate treatment effects accounting for clustering and adjusting for covariates, their properties under misspecification have not been systematically explored. In this article, we focus on model-based methods, including linear mixed models and generalized estimating equations…

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Estimation and Inference for Causal Functions with Multiway Clustered Data

多维聚类数据下因果函数的估计与推断

This paper proposes methods of estimation and uniform inference for a general class of causal functions, such as the conditional average treatment effects and the continuous treatment effects, under multiway clustering. The causal function is identified as a conditional expectation of an adjusted (Neyman-orthogonal) signal that depends on high-dimensional nuisance parameters. We propose a two-step procedure where the first step uses machine learning to estimate the…

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Self-convolved Bootstrap for M-regression under Complex Temporal Dynamics

复杂时间动态下 M 回归的自卷积 Bootstrap

The paper considers simultaneous nonparametric inference for a wide class of M-regression models with time-varying coefficients. The covariates and errors of the regression model are tackled as a general class of nonstationary time series and are allowed to be cross-dependent. A novel and easy-to-implement self-convolved bootstrap procedure is proposed. With only one tuning parameter, the bootstrap facilitates a $\sqrt{n}$-consistent inference of the cumulative regression…

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Incorporating external data for analyzing randomized clinical trials: A transfer learning approach

利用外部数据分析随机临床试验:迁移学习方法

Randomized clinical trials are the gold standard for analyzing treatment effects, but high costs and ethical concerns can limit recruitment, potentially leading to invalid inferences. Incorporating external trial data with similar characteristics into the analysis using transfer learning appears promising for addressing these issues. In this paper, we present a formal framework for applying transfer learning to the analysis of clinical trials, considering three key…

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Safe Policy Learning under Regression Discontinuity Designs with Multiple Cutoffs

多阈值断点回归设计下的安全政策学习

The regression discontinuity (RD) design is widely used for program evaluation with observational data. The primary focus of the existing literature has been the estimation of the local average treatment effect at the existing treatment cutoff. In contrast, we consider policy learning under the RD design. Because the treatment assignment mechanism is deterministic, learning better treatment cutoffs requires extrapolation. We develop a robust optimization approach to finding…

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