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Debiased machine learning for counterfactual survival functionals based on left-truncated right-censored data

基于左截断右删失数据的反事实生存泛函去偏机器学习

Learning causal effects of a binary exposure on time-to-event endpoints can be challenging because survival times may be partially observed due to censoring and systematically biased due to truncation. In this work, we present debiased machine learning-based nonparametric estimators of the joint distribution of a counterfactual survival time and baseline covariates for use when the observed data are subject to covariate-dependent left truncation and right censoring and when…

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Adaptive Shrinkage with a Nonparametric Bayesian Lasso

自适应收缩:非参数贝叶斯 Lasso

Modern approaches to perform Bayesian variable selection rely mostly on the use of shrinkage priors. That said, an ideal shrinkage prior should be adaptive to different signal levels, ensuring that small effects are ruled out, while keeping relatively intact the important ones. With this task in mind, we develop the nonparametric Bayesian Lasso, an adaptive and flexible shrinkage prior for Bayesian regression and variable selection, particularly useful when the number of…

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Improving randomized controlled trial analysis via data-adaptive borrowing

通过数据自适应借用外部对照改进随机试验分析

In recent years, real-world external controls have grown in popularity as a tool to empower randomized placebo-controlled trials, particularly in rare diseases or cases where balanced randomization is unethical or impractical. However, as external controls are not always comparable to the trials, direct borrowing without scrutiny may heavily bias the treatment effect estimator. Our paper proposes a data-adaptive integrative framework capable of preventing unknown biases of…

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Strong Approximations for Empirical Processes Indexed by Lipschitz Functions

由 Lipschitz 函数索引的经验过程强逼近

This paper presents new uniform Gaussian strong approximations for empirical processes indexed by classes of functions based on $d$-variate random vectors ($d\geq1$). First, a uniform Gaussian strong approximation is established for general empirical processes indexed by possibly Lipschitz functions, improving on previous results in the literature. In the setting considered by Rio (1994), and if the function class is Lipschitzian, our result improves the approximation rate $n^{-1/(2d)}$…

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Flexible Functional Treatment Effect Estimation

灵活的函数型处理效应估计

We study treatment effect estimation with functional treatments where the average potential outcome functional is a function of functions, in contrast to continuous treatment effect estimation where the target is a function of real numbers. By considering a flexible scalar-on-function marginal structural model, a weight-modified kernel ridge regression (WMKRR) is adopted for estimation. The weights are constructed by directly minimizing the uniform balancing error resulting…

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Nonparametric estimation of linear multiplier for stochastic differential equations driven by multiplicative stochastic volatility

乘性随机波动率驱动随机微分方程的线性乘子非参数估计

We study the problem of nonparametric estimation of the linear multiplier function $θ(t)$ for processes satisfying stochastic differential equations of the type $$dX_t= θ(t)X_t dt+ ε\; σ_1(t,X_t)σ_2(t,Y_t)dW_t, X_0=x_0, 0 \leq t \leq T$$ where $\{W_t, t\geq 0\}$ is a standard Brownian motion, $\{Y_t, t\geq 0\}$ is a process adapted to the filtration generated by the Brownian motion. We study the problem of estimation of the unknown function $θ(.)$ as $ε\rightarrow 0$ based…

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Nonparametric estimation of trend for stochastic differential equations driven by multiplicative stochastic volatility

乘性随机波动率驱动随机微分方程的趋势非参数估计

We discuss nonparametric estimation of the trend coefficient in models governed by a stochastic differential equation driven by a multiplicative stochastic volatility.

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Valid Credible Ellipsoids for Linear Functionals by a Renormalized Bernstein-von Mises Theorem

重归一化 Bernstein-von Mises 定理下的线性泛函有效可信椭球

We consider an infinite-dimensional Gaussian regression model, equipped with a high-dimensional Gaussian prior. We address the frequentist validity of posterior credible sets for a vector of linear functionals. We specify conditions for a 'renormalized' Bernstein-von Mises theorem (BvM), where the posterior, centered at its mean, and the posterior mean, centered at the ground truth, have the same normal approximation. This requires neither a solution to the information…

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Regularization of the ensemble Kalman filter using a non-parametric, non-stationary spatial model

用非参数非平稳空间模型正则化集合卡尔曼滤波

The sample covariance matrix of a random vector is a good estimate of the true covariance matrix if the sample size is much larger than the length of the vector. In high-dimensional problems, this condition is never met. As a result, in high dimensions the Ensemble Kalman Filter's (EnKF) ensemble does not contain enough information to specify the prior covariance matrix accurately. This necessitates the need for regularization of the analysis (observation update) problem. We…

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Statistical Agnostic Regression: a machine learning method to validate regression models

统计不可知回归:验证回归模型的机器学习方法

Regression analysis is a central topic in statistical modeling, aimed at estimating the relationships between a dependent variable, commonly referred to as the response variable, and one or more independent variables, i.e., explanatory variables. Linear regression is by far the most popular method for performing this task in various fields of research, such as data integration and predictive modeling when combining information from multiple sources. Classical methods for…

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Short-time expansion of characteristic functions in a rough volatility setting with applications

粗糙波动率下特征函数的短时展开及其应用

We derive a higher-order asymptotic expansion of the conditional characteristic function of the increment of an Itô semimartingale over a shrinking time interval. The spot characteristics of the Itô semimartingale are allowed to have dynamics of general form. In particular, their paths can be rough, that is, exhibit local behavior like that of a fractional Brownian motion, while at the same time have jumps with arbitrary degree of activity. The expansion result shows the…

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Hierarchical Regression Discontinuity Design: Pursuing Subgroup Treatment Effects

层级断点回归设计:估计子群体处理效应

Regression discontinuity design (RDD) is widely adopted for causal inference under intervention determined by a continuous variable. While one is interested in treatment effect heterogeneity by subgroups in many applications, RDD typically suffers from small subgroup-wise sample sizes, which makes the estimation results highly instable. To solve this issue, we introduce hierarchical RDD (HRDD), a hierarchical Bayes approach for pursuing treatment effect heterogeneity in RDD.…

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Adaptive, Rate-Optimal Hypothesis Testing in Nonparametric IV Models

非参数工具变量模型中的自适应最优速率假设检验

We propose a new adaptive hypothesis test for inequality (e.g., monotonicity, convexity) and equality (e.g., parametric, semiparametric) restrictions on a structural function in a nonparametric instrumental variables (NPIV) model. Our test statistic is based on a modified leave-one-out sample analog of a quadratic distance between the restricted and unrestricted sieve two-stage least squares estimators. We provide computationally simple, data-driven choices of sieve tuning…

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Mind the spikes: Benign overfitting of kernels and neural networks in fixed dimension

注意尖峰:固定维度下核方法与神经网络的有益过拟合

The success of over-parameterized neural networks trained to near-zero training error has caused great interest in the phenomenon of benign overfitting, where estimators are statistically consistent even though they interpolate noisy training data. While benign overfitting in fixed dimension has been established for some learning methods, current literature suggests that for regression with typical kernel methods and wide neural networks, benign overfitting requires a…

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Double Robust Variance Estimation with Parametric Working Models

参数工作模型下的双重稳健方差估计

Doubly robust estimators have gained popularity in the field of causal inference due to their ability to provide consistent point estimates when either an outcome or exposure model is correctly specified. However, for nonrandomized exposures the influence function based variance estimator frequently used with doubly robust estimators of the average causal effect is only consistent when both working models (i.e., outcome and exposure models) are correctly specified. Here, the…

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Modeling the restricted mean survival time using pseudo-value random forests

利用伪值随机森林建模限制平均生存时间

The restricted mean survival time (RMST) has become a popular measure to summarize event times in longitudinal studies. Defined as the area under the survival function up to a time horizon $τ$ > 0, the RMST can be interpreted as the life expectancy within the time interval [0, $τ$]. In addition to its straightforward interpretation, the RMST also allows for the definition of valid estimands for the causal analysis of treatment contrasts in medical studies. In this work, we…

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A Semiparametric Approach to Causal Inference

因果推断的半参数方法:反事实分布与密度比模型

In causal inference, an important problem is to quantify the effects of interventions or treatments. Many studies focus on estimating the mean causal effects; however, these estimands may offer limited insight since two distributions can share the same mean yet exhibit significant differences. Examining the causal effects from a distributional perspective provides a more thorough understanding. In this paper, we employ a semiparametric density ratio model (DRM) to…

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Inference in a Stationary/Nonstationary Autoregressive Time-Varying-Parameter Model

平稳与非平稳时变参数自回归模型中的推断

This paper considers nonparametric estimation and inference in first-order autoregressive (AR(1)) models with deterministically time-varying parameters. A key feature of the proposed approach is to allow for time-varying stationarity in some time periods, time-varying nonstationarity (i.e., unit root or local-to-unit root behavior) in other periods, and smooth transitions between the two. The estimation of the AR parameter at any time point is based on a local least squares…

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Estimating Broad Sense Heritability via Kernel Ridge Regression

基于核岭回归的广义遗传力估计

The broad sense genetic heritability, which quantifies the total proportion of phenotypic variation in a population due to genetic factors, is crucial for understanding trait inheritance. While many existing methods focus on estimating narrow sense heritability, which accounts only for additive genetic variation, this paper introduces a kernel ridge regression approach to estimate broad-sense heritability. We provide both upper and lower bounds for the estimator. The…

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Machine Learning Debiasing with Conditional Moment Restrictions: An Application to LATE

条件矩限制下的机器学习去偏:局部平均处理效应应用

Models with Conditional Moment Restrictions (CMRs) are popular in economics. These models involve finite and infinite dimensional parameters. The infinite dimensional components include conditional expectations, conditional choice probabilities, or policy functions, which might be flexibly estimated using Machine Learning tools. This paper presents a characterization of locally debiased moments for regular models defined by general semiparametric CMRs with possibly different…

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An Overview of Causal Inference using Kernel Embeddings

利用核嵌入开展因果推断的研究概览

Kernel embeddings have emerged as a powerful tool for representing probability measures in a variety of statistical inference problems. By mapping probability measures into a reproducing kernel Hilbert space (RKHS), kernel embeddings enable flexible representations of complex relationships between variables. They serve as a mechanism for efficiently transferring the representation of a distribution downstream to other tasks, such as hypothesis testing or causal effect…

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Inference in Partially Linear Models under Dependent Data with Deep Neural Networks

依赖数据下使用深度神经网络的部分线性模型推断

I consider inference in a partially linear regression model under stationary $β$-mixing data after first stage deep neural network (DNN) estimation. Using the DNN results of Brown (2024), I show that the estimator for the finite dimensional parameter, constructed using DNN-estimated nuisance components, achieves $\sqrt{n}$-consistency and asymptotic normality. By avoiding sample splitting, I address one of the key challenges in applying machine learning techniques to…

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Nonparametric Density Estimation for Data Scattered on Irregular Spatial Domains: A Likelihood-Based Approach Using Bivariate Penalized Spline Smoothing

不规则空间域散点数据的双变量惩罚样条非参数密度估计

Accurately estimating data density is crucial for making informed decisions and modeling in various fields. This paper presents a novel nonparametric density estimation procedure that utilizes bivariate penalized spline smoothing over triangulation for data scattered over irregular spatial domains. The approach is likelihood-based with a regularization term that addresses the roughness of the logarithm of density based on a second-order differential operator. The proposed…

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Rate-optimal estimation of mixed semimartingales

混合半鞅的速率最优估计

Consider the sum $Y=B+B(H)$ of a Brownian motion $B$ and an independent fractional Brownian motion $B(H)$ with Hurst parameter $H\in(0,1)$. Even though $B(H)$ is not a semimartingale, it was shown in [\textit{Bernoulli} \textbf{7} (2001) 913--934] that $Y$ is a semimartingale if $H>3/4$. Moreover, $Y$ is locally equivalent to $B$ in this case, so $H$ cannot be consistently estimated from local observations of $Y$. This paper pivots on another unexpected feature in this…

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