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A Note on Local Linear Regression for Time Series in Banach Spaces

Banach 空间值时间序列的局部线性回归札记

This work extends local linear regression to Banach space-valued time series for estimating smoothly varying means and their derivatives in non-stationary data. The asymptotic properties of both the standard and bias-reduced Jackknife estimators are analyzed under mild moment conditions, establishing their convergence rates. Simulation studies assess the finite sample performance of these estimators and compare them with the Nadaraya-Watson estimator. Additionally, the…

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Uniform Convergence Rate of the Nonparametric Estimator for Integrated Diffusion Processes

积分扩散过程非参数估计量的一致收敛速度

The nonparametric estimation of integrated diffusion processes has been extensively studied, with most existing research focusing on pointwise convergence. This paper is the first to establish uniform convergence rates for the Nadaraya-Watson estimators of their coefficients. We derive these rates over unbounded support under the assumptions of a vanishing observation interval and a long time horizon. Our findings serve as essential tools for specification testing and…

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A Unified Framework for Semiparametrically Efficient Semi-Supervised Learning

半参数有效半监督学习的统一框架

We consider statistical inference under a semi-supervised setting where we have access to both a labeled dataset consisting of pairs $\{X_i, Y_i \}_{i=1}^n$ and an unlabeled dataset $\{ X_i \}_{i=n+1}^{n+N}$. We ask the question: under what circumstances, and by how much, can incorporating the unlabeled dataset improve upon inference using the labeled data? To answer this question, we investigate semi-supervised learning through the lens of semiparametric efficiency theory.…

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Minnesota BART

Minnesota BART:面向宏观预测的稀疏与滞后收缩树先验

Vector autoregression (VAR) models are widely used for forecasting and macroeconomic analysis, yet they remain limited by their reliance on a linear parameterization. Recent research has introduced nonparametric alternatives, such as Bayesian additive regression trees (BART), which provide flexibility without strong parametric assumptions. However, existing BART-based frameworks do not account for time dependency or allow for sparse estimation in the construction of…

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Nonparametric estimation of conditional densities by generalized random forests

利用广义随机森林非参数估计条件密度

Considering a continuous random variable Y together with a continuous random vector X, I propose a nonparametric estimator f^(.|x) for the conditional density of Y given X=x. This estimator takes the form of an exponential series whose coefficients Tx = (Tx1,...,TxJ) are the solution of a system of nonlinear equations that depends on an estimator of the conditional expectation E[p(Y)|X=x], where p is a J-dimensional vector of basis functions. The distinguishing feature of…

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Debiased Nonparametric Regression for Statistical Inference and Distributionally Robustness

用于统计推断与分布稳健性的去偏非参数回归

This study proposes a debiasing method for smooth nonparametric estimators. While machine learning techniques such as random forests and neural networks have demonstrated strong predictive performance, their theoretical properties remain relatively underexplored. In particular, many modern algorithms lack guarantees of pointwise and uniform risk convergence, as well as asymptotic normality. These properties are essential for statistical inference and robust estimation and…

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fkbma: An R Package for Detecting Tailoring Variables with Free-Knot B-Splines and Bayesian Model Averaging

fkbma:以自由节点 B 样条和贝叶斯模型平均识别治疗定制变量的 R 包

Precision medicine aims to optimize treatment by identifying patient subgroups most likely to benefit from specific interventions. To support this goal, we introduce fkbma, an R package that implements a Bayesian model averaging approach with free-knot B-splines for identifying tailoring variables. The package employs a reversible jump Markov chain Monte Carlo algorithm to flexibly model treatment effect heterogeneity while accounting for uncertainty in both variable…

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A robust score test in g-computation for covariate adjustment in randomized clinical trials leveraging different variance estimators via influence functions

随机临床试验协变量调整中基于影响函数方差的稳健 g 计算得分检验

G-computation has become a widely used robust method for estimating unconditional (marginal) treatment effects with covariate adjustment in the analysis of randomized clinical trials. Statistical inference in this context typically relies on the Wald test or Wald interval, which can be easily implemented using a consistent variance estimator. However, existing literature suggests that when sample sizes are small or when parameters of interest are near boundary values,…

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H-AddiVortes: Heteroscedastic (Bayesian) Additive Voronoi Tessellations

异方差贝叶斯加性 Voronoi 镶嵌模型

This paper introduces the Heteroscedastic AddiVortes model, a Bayesian non-parametric regression framework that simultaneously models the conditional mean and variance of a response variable using adaptive Voronoi tessellations. By employing a sum-of-tessellations approach for the mean and a product-of-tessellations approach for the variance, the model provides a flexible and interpretable means to capture complex, predictor-dependent relationships and heteroscedastic…

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A Doubly Robust Instrumental Variable Approach for Estimating Average Treatment Effects in Time-to-Event Data with Unmeasured Confounding: Application to Real-World Data on ICU Patients with Septic Shock

未测混杂下生存结局平均处理效应的双重稳健工具变量方法

Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE) in time-to-event data. In real-world data, IV methods are widely used for estimating causal treatment effects in the presence of unmeasured confounding, but existing approaches for time-to-event outcomes are often constrained by strong…

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Sequential Kernel Embedding for Mediated and Time-Varying Dose Response Curves

中介与时变剂量反应曲线的序贯核嵌入

We propose simple nonparametric estimators for mediated and time-varying dose response curves based on kernel ridge regression. By embedding Pearl's mediation formula and Robins' g-formula with kernels, we allow treatments, mediators, and covariates to be continuous in general spaces, and also allow for nonlinear treatment-confounder feedback. Our key innovation is a reproducing kernel Hilbert space technique called sequential kernel embedding, which we use to construct…

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BudgetIV: Optimal Partial Identification of Causal Effects with Mostly Invalid Instruments

BudgetIV:多数工具变量无效时因果效应的最优部分识别

Instrumental variables (IVs) are widely used to estimate causal effects in the presence of unobserved confounding between exposure and outcome. An IV must affect the outcome exclusively through the exposure and be unconfounded with the outcome. We present a framework for relaxing either or both of these strong assumptions with tuneable and interpretable budget constraints. Our algorithm returns a feasible set of causal effects that can be identified exactly given relevant…

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Causal Representation Learning from Multimodal Biomedical Observations

从多模态生物医学观测中学习因果表征

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these datasets often lack interpretability and identifiability guarantees, which are essential for biomedical research. Recent advances in causal representation learning have shown promise in identifying interpretable latent causal variables with…

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Longitudinal Causal Inference with Selective Eligibility

具有选择性资格的纵向因果推断

Dropout poses a significant challenge to causal inference in longitudinal studies with time-varying treatments. However, existing research does not simultaneously address dropout and time-varying treatments. We examine selective eligibility, an important yet overlooked source of non-ignorable dropout in such settings. This problem arises when a unit's prior treatment history influences its eligibility for subsequent treatments, a common scenario in medical and other…

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Excess Mean Squared Error of Empirical Bayes Estimators

经验贝叶斯估计量的超额均方误差

Empirical Bayes estimators are based on minimizing the average risk with the hyper-parameters in the weighting function being estimated from observed data. The performance of an empirical Bayes estimator is typically evaluated by its mean squared error (MSE). However, the explicit expression for its MSE is generally unavailable for finite sample sizes. To address this issue, we define a high-order analytical criterion: the excess MSE. It quantifies the performance difference…

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Modeling complex measurement error in microbiome experiments to estimate relative abundances and detection effects

微生物组实验中复杂测量误差的建模:相对丰度与检测效应估计

Accurate estimates of microbial species abundances are needed to advance our understanding of the role that microbiomes play in human and environmental health. However, artificially constructed microbiomes demonstrate that intuitive estimators of microbial relative abundances are biased. To address this, we propose a semiparametric method to estimate relative abundances, species detection effects, and/or cross-sample contamination in microbiome experiments. We show that…

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Non-Asymptotic Analysis of Classical Spectrum Estimators with $L$-mixing Time-series Data

L-mixing 时间序列下经典谱估计量的非渐近分析

Spectral estimation is a fundamental problem for time series analysis, which is widely applied in economics, speech analysis, seismology, and control systems. The asymptotic convergence theory for classical, non-parametric estimators, is well-understood, but the non-asymptotic theory is still rather limited. Our recent work gave the first non-asymptotic error bounds on the well-known Bartlett and Welch methods, but under restrictive assumptions. In this paper, we derive…

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Self-Consistent Equation-guided Neural Networks for Censored Time-to-Event Data

自洽方程引导的神经网络用于删失时间事件数据

In survival analysis, estimating the conditional survival function given predictors is often of interest. There is a growing trend in the development of deep learning methods for analyzing censored time-to-event data, especially when dealing with high-dimensional predictors that are complexly interrelated. Many existing deep learning approaches for estimating the conditional survival functions extend the Cox regression models by replacing the linear function of predictor…

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On a new robust method of inference for general time series models

一般时间序列模型的一种稳健推断新方法

In this article, we propose a novel logistic quasi-maximum likelihood estimation (LQMLE) for general parametric time series models. Compared to the classical Gaussian QMLE and existing robust estimations, it enjoys many distinctive advantages, such as robustness in respect of distributional misspecification and heavy-tailedness of the innovation, more resiliency to outliers, smoothness and strict concavity of the log logistic quasi-likelihood function, and boundedness of the…

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Change-point regression with a smooth additive disturbance

含平滑加性扰动的变点回归

We assume a nonparametric regression model where the signal is given by the sum of a piecewise constant function and a smooth function. To detect the change-points and estimate the regression functions, we propose PCpluS, a combination of the fused Lasso and kernel smoothing. In contrast to existing approaches, it explicitly uses the additive decomposition of the signal when detecting change-points. This is motivated by several applications and by theoretical results about…

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Doubly robust omnibus sensitivity analysis of externally controlled trials with intercurrent events

存在试验期间事件的外部对照试验:双重稳健综合敏感性分析

Externally controlled trials are crucial in clinical development when randomized controlled trials are unethical or impractical. These trials consist of a full treatment arm with the experimental treatment and a full external control arm. However, they present significant challenges in learning the treatment effect due to the lack of randomization and a parallel control group. Besides baseline incomparability, outcome mean non-exchangeability, caused by differences in…

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lpcde: Estimation and Inference for Local Polynomial Conditional Density Estimators

lpcde:局部多项式条件密度估计与推断

This paper discusses the R package lpcde, which stands for local polynomial conditional density estimation. It implements the kernel-based local polynomial smoothing methods introduced in Cattaneo, Chandak, Jansson, Ma (2024) for statistical estimation and inference of conditional distributions, densities, and derivatives thereof. The package offers mean square error optimal bandwidth selection and associated point estimators, as well as uncertainty quantification based on…

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Fast Robust Kernel Regression through Sign Gradient Descent with Early Stopping

基于符号梯度下降与早停的快速稳健核回归

Kernel ridge regression, KRR, is a generalization of linear ridge regression that is non-linear in the data, but linear in the model parameters. Here, we introduce an equivalent formulation of the objective function of KRR, which opens up for replacing the ridge penalty with the $\ell_\infty$ and $\ell_1$ penalties. Using the $\ell_\infty$ and $\ell_1$ penalties, we obtain robust and sparse kernel regression, respectively. We study the similarities between explicitly…

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Fundamentals of non-parametric statistical inference for integrated quantiles

分位数积分的非参数统计推断基础

We present a general non-parametric statistical inference theory for integrals of quantiles without assuming any specific sampling design or dependence structure. Technical considerations are accompanied by examples and discussions, including those pertaining to the bias of empirical estimators. To illustrate how the general results can be adapted to specific situations, we derive - at a stroke and under minimal conditions - consistency and asymptotic normality of the…

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