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Identification and estimation of causal peer effects using instrumental variables

利用工具变量识别和估计因果同伴效应

In social science researches, causal inference regarding peer effects often faces significant challenges due to homophily bias and contextual confounding. For example, unmeasured health conditions (e.g., influenza) and psychological states (e.g., happiness, loneliness) can spread among closely connected individuals, such as couples or siblings. To address these issues, we define four effect estimands for dyadic data to characterize direct effects and spillover effects. We…

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ReLU integral probability metric and its applications

ReLU 积分概率度量及其应用

We propose a parametric integral probability metric (IPM) to measure the discrepancy between two probability measures. The proposed IPM leverages a specific parametric family of discriminators, such as single-node neural networks with ReLU activation, to effectively distinguish between distributions, making it applicable in high-dimensional settings. By optimizing over the parameters of the chosen discriminator class, the proposed IPM demonstrates that its estimators have…

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Regularized Generalized Covariance (RGCov) Estimator

正则化广义协方差估计量

We introduce a regularized Generalized Covariance (RGCov) estimator as an extension of the GCov estimator to high dimensional setting that results either from high-dimensional data or a large number of nonlinear transformations used in the objective function. The approach relies on a ridge-type regularization for high-dimensional matrix inversion in the objective function of the GCov. The RGCov estimator is consistent and asymptotically normally distributed. We provide the…

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Bernstein Polynomial Processes for Continuous Time Change Detection

用于连续时间变化检测的伯恩斯坦多项式过程

There is a lack of methodological results for continuous time change detection due to the challenges of noninformative prior specification and efficient posterior inference in this setting. Most methodologies to date assume data are collected according to uniformly spaced time intervals. This assumption incurs bias in the continuous time setting where, a priori, two consecutive observations measured closely in time are less likely to change than two consecutive observations…

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Estimation and Inference for the Average Treatment Effect in a Score-Explained Heterogeneous Treatment Effect Model

分数解释型异质处理效应模型中的平均处理效应估计与推断

In many practical situations, randomly assigning treatments to subjects is uncommon due to feasibility constraints. For example, economic aid programs and merit-based scholarships are often restricted to those meeting specific income or exam score thresholds. In these scenarios, traditional approaches to estimating treatment effects typically focus solely on observations near the cutoff point, thereby excluding a significant portion of the sample and potentially leading to…

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Causal machine learning for high-dimensional mediation analysis using interventional effects mapped to a target trial

映射至目标试验的干预效应:高维中介分析中的因果机器学习

Causal mediation analysis examines causal pathways linking exposures to disease. The estimation of interventional effects, which are mediation estimands that overcome certain identifiability problems of natural effects, has been advanced through causal machine learning methods, particularly for high-dimensional mediators. Recently, it has been proposed interventional effects can be defined in each study by mapping to a target trial assessing specific hypothetical mediator…

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Benign overfitting in Fixed Dimension via Physics-Informed Learning with Smooth Inductive Bias

固定维度下带平滑归纳偏置的物理信息学习中的良性过拟合

Recent advances in machine learning have inspired a surge of research into reconstructing specific quantities of interest from measurements that comply with certain physical laws. These efforts focus on inverse problems that are governed by partial differential equations (PDEs). In this work, we develop an asymptotic Sobolev norm learning curve for kernel ridge(less) regression when addressing (elliptical) linear inverse problems. Our results show that the PDE operators in…

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How Much Weak Overlap Can Doubly Robust T-Statistics Handle?

双重稳健 t 统计量能够承受多弱的重叠?

In the presence of sufficiently weak overlap, it is known that no regular root-n-consistent estimators exist and standard estimators may fail to be asymptotically normal. This paper shows that a thresholded version of the standard doubly robust estimator is asymptotically normal with well-calibrated Wald confidence intervals even when constructed using nonparametric estimates of the propensity score and conditional mean outcome. The analysis implies a cost of weak overlap in…

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Causal Inference for Genomic Data with Multiple Heterogeneous Outcomes

具有多个异质结局的基因组数据因果推断

With the evolution of single-cell RNA sequencing techniques into a standard approach in genomics, it has become possible to conduct cohort-level causal inferences based on single-cell-level measurements. However, the individual gene expression levels of interest are not directly observable; instead, only repeated proxy measurements from each individual's cells are available, providing a derived outcome to estimate the underlying outcome for each of many genes. In this paper,…

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Efficient Testing Using Surrogate Information

利用替代指标信息进行高效检验

In modern clinical trials, there is immense pressure to use surrogate markers in place of an expensive or long-term primary outcome to make more timely decisions about treatment effectiveness. However, using a surrogate marker to test for a treatment effect can be difficult and controversial. Existing methods tend to either rely on fully parametric methods where strict assumptions are made about the relationship between the surrogate and the outcome, or assume the surrogate…

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Efficient estimation and data fusion under general semiparametric restrictions on outcome mean functions

结局均值函数一般半参数约束下的有效估计与数据融合

We provide a novel characterization of semiparametric efficiency in a generic supervised learning setting where the outcome mean function -- defined as the conditional expectation of the outcome of interest given the other observed variables -- is restricted to lie in some known semiparametric function class. The primary motivation is causal inference where a researcher running a randomized controlled trial often has access to an auxiliary observational dataset that is…

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Nonparametric mixed logit model with market-level parameters estimated from market share data

利用市场份额数据估计市场层级参数的非参数混合 Logit 模型

We propose a nonparametric mixed logit model that is estimated using market-level choice share data. The model treats each market as an agent and represents taste heterogeneity through market-specific parameters by solving a multiagent inverse utility maximization problem, addressing the limitations of existing market-level choice models with parametric estimation. A simulation study is conducted to evaluate the performance of our model in terms of estimation time,…

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A Bayesian nonparametric approach to mediation and spillover effects with multiple mediators in cluster-randomized trials

整群随机试验中多重中介与溢出效应的贝叶斯非参数方法

Cluster randomized trials (CRTs) with multiple unstructured mediators present significant methodological challenges for causal inference due to within-cluster correlation, interference among units, and the complexity introduced by multiple mediators. Existing causal mediation methods often fall short in simultaneously addressing these complexities, particularly in disentangling mediator-specific effects under interference that are central to studying complex mechanisms. To…

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Doubly Robust Inference on Causal Derivative Effects for Continuous Treatments

连续处理因果导数效应的双重稳健推断

Statistical methods for causal inference with continuous treatments mainly focus on estimating the mean potential outcome function, commonly known as the dose-response curve. However, it is often not the dose-response curve but its derivative function that signals the treatment effect. In this paper, we investigate nonparametric inference on the derivative of the dose-response curve with and without the positivity condition. Under the positivity and other regularity…

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Towards R-learner with Continuous Treatments

迈向连续处理的 R-learner

The R-learner is widely used in causal inference due to its flexibility and efficiency in estimating the conditional average treatment effect. However, extending the R-learner framework from binary to continuous treatments introduces a non-identifiability issue, as the functional zero constraint inherent to the conditional average treatment effect cannot be directly imposed in the R-loss under continuous treatments. To address this, we propose a two-step identification…

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Semiparametric Causal Discovery and Inference with Invalid Instruments

容许无效工具变量的半参数因果发现与推断

Learning causal relationships among a set of variables, as encoded by a directed acyclic graph, from observational data is complicated by the presence of unobserved confounders. Instrumental variables (IVs) are a popular remedy for this issue, but most existing methods either assume the validity of all IVs or postulate a specific form of relationship, such as a linear model, between the primary variables and the IVs. To overcome these limitations, we introduce a partially…

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A unified test for regression discontinuity designs

断点回归设计的统一诊断检验

Diagnostic tests for regression discontinuity design face a size-control problem. We document a massive over-rejection of the diagnostic restriction among empirical studies in the top five economics journals. At least one diagnostic test was rejected for 19 out of 59 studies, whereas less than 5% of the collected 787 tests rejected the null hypotheses. In other words, one-third of the studies rejected at least one of their diagnostic tests, whereas their underlying…

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Improved Convergence Rate of Nested Simulation with LSE on Sieve

基于筛最小二乘估计的嵌套模拟收敛速率改进

Nested simulation encompasses the estimation of functionals linked to conditional expectations through simulation techniques. In this paper, we treat conditional expectation as a function of the multidimensional conditioning variable and provide asymptotic analyses of general Least Squared Estimators on sieve, without imposing specific assumptions on the function's form. Our study explores scenarios in which the convergence rate surpasses that of the standard Monte Carlo…

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Bayesian analysis of regression discontinuity designs with heterogeneous treatment effects

异质处理效应断点回归设计的贝叶斯分析

Regression Discontinuity Design (RDD) is a popular framework for estimating a causal effect in settings where treatment is assigned if an observed covariate exceeds a fixed threshold. We consider estimation and inference in the common setting where the sample consists of multiple known sub-populations with potentially heterogeneous treatment effects. In the applied literature, it is common to account for heterogeneity by either fitting a parametric model or considering each…

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A Nonparametric Approach with Marginals for Modeling Consumer Choice

利用边际分布建模消费者选择的非参数方法

Given data on the choices made by consumers for different offer sets, a key challenge is to develop parsimonious models that describe and predict consumer choice behavior while being amenable to prescriptive tasks such as pricing and assortment optimization. The marginal distribution model (MDM) is one such model, which requires only the specification of marginal distributions of the random utilities. This paper aims to establish necessary and sufficient conditions for given…

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Automatic debiasing of neural networks via moment-constrained learning

通过矩约束学习实现神经网络自动去偏

Causal and nonparametric estimands in economics and biostatistics can often be viewed as the mean of a linear functional applied to an unknown outcome regression function. Naively learning the regression function and taking a sample mean of the target functional results in biased estimators, and a rich debiasing literature has developed where one additionally learns the so-called Riesz representer (RR) of the target estimand (targeted learning, double ML, automatic debiasing…

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Inverse Probability Weighting: from Survey Sampling to Evidence Estimation

逆概率加权:从调查抽样到贝叶斯证据估计

We consider the class of inverse probability weight (IPW) estimators, including the popular Horvitz-Thompson and Hajek estimators used routinely in survey sampling, causal inference and evidence estimation for Bayesian computation. We focus on the 'weak paradoxes' for these estimators due to two counterexamples by Basu [1988] and Wasserman [2004] and investigate the two natural Bayesian answers to this problem: one based on binning and smoothing : a 'Bayesian sieve' and the…

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Semiparametric Growth-Curve Modeling in Hierarchical, Longitudinal Studies

层级纵向研究中的半参数生长曲线建模

Modeling of growth (or decay) curves arises in many fields such as microbiology, epidemiology, marketing, and econometrics. Parametric forms like Logistic and Gompertz are often used for modeling such monotonic patterns. While useful for compact description, the real-life growth curves rarely follow these parametric forms perfectly. Therefore, the curve estimation methods that strike a balance between prior information in the parametric form and fidelity with the observed…

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Nonparametric efficient causal estimation of the intervention-specific expected number of recurrent events with continuous-time targeted maximum likelihood and highly adaptive lasso estimation

连续时间靶向极大似然与高度自适应 Lasso 的干预特定复发事件期望次数估计

Longitudinal settings involving outcome, competing risks and censoring events occurring and recurring in continuous time are common in medical research, but are often analyzed with methods that do not allow for taking post-baseline information into account. In this work, we define statistical and causal target parameters via the g-computation formula by carrying out interventions directly on the product integral representing the observed data distribution in a…

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