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rdhte：断点回归设计中的条件平均处理效应AI 解读

Understanding causal heterogeneous treatment effects based on pretreatment covariates is a crucial aspect of empirical work. Building on Calonico, Cattaneo, Farrell, Palomba, and Titiunik (2025), this article discusses the software package rdhte for estimation and inference of heterogeneous treatment effects in sharp regression discontinuity (RD) designs. The package includes three main commands: rdhte conducts estimation and robust bias-corrected inference for heterogeneous…

光遗传学的非参数因果推断：动态方案中的序贯偏离效应AI 解读

Optogenetics is a powerful neuroscience technique for studying how neural circuit manipulation affects behavior. Standard analysis conventions discard information and severely limit the scope of the causal questions that can be probed. To address this gap, we 1) draw connections to the causal inference literature on sequentially randomized experiments, 2) propose a non-parametric framework for analyzing "open-loop" (static regime) optogenetics behavioral experiments, 3)…

近似流形上协变量偏移的非参数极小极大速率相变AI 解读

We study nonparametric regression under covariate shift with structured data, where a small amount of labeled target data is supplemented by a large labeled source dataset. In many real-world settings, the covariates in the target domain lie near a low-dimensional manifold within the support of the source, e.g., personalized handwritten digits (target) within a large, high-dimensional image repository (source). Since density ratios may not exist in these settings, standard…

利用共单调性外推断点回归中的因果效应AI 解读

We present a novel approach for extrapolating causal effects away from the margin between treatment and non-treatment in sharp regression discontinuity designs with multiple covariates. Our methods apply both to settings in which treatment is a function of multiple observables and settings in which treatment is determined based on a single running variable. Our key identifying assumption is that conditional average treated and untreated potential outcomes are comonotonic:…

容许多个无效代理变量的强化近端因果推断AI 解读

Causal inference from observational data often relies on the assumption of no unmeasured confounding, an assumption frequently violated in practice due to unobserved or poorly measured covariates. Proximal causal inference (PCI) offers a promising framework for addressing unmeasured confounding using a pair of outcome and treatment confounding proxies. However, existing PCI methods typically assume all specified proxies are valid, which may be unrealistic and is untestable…

时变非线性时间序列回归的筛估计与同时推断AI 解读

In this paper, we investigate time-varying nonlinear time series regression for a broad class of locally stationary time series. First, we propose sieve nonparametric estimators for the time-varying regression functions that achieve uniform consistency. Second, we develop a unified simultaneous inferential theory to conduct both structural and exact form tests on these functions. Additionally, we introduce a multiplier bootstrap procedure for practical implementation. Our…

平均分位数回归：一种新的非均值回归模型与一致风险度量AI 解读

Regression models that go beyond the mean, alongside coherent risk measures, have been important tools in modern data analysis. This paper introduces the innovative concept of Average Quantile Regression (AQR), which is smooth at the quantile-like level, comonotonically additive, and explicitly accounts for the severity of tail losses relative to quantile regression. AQR serves as a versatile regression model capable of describing distributional information across all…

协变量不可忽略缺失下最优动态治疗方案的稳健估计AI 解读

Estimating optimal dynamic treatment regimes (DTRs) using observational data is often challenged by nonignorable missing covariates arsing from informative monitoring of patients in clinical practice. To address nonignorable missingness of pseudo-outcomes induced by nonignorable missing covariates, a weighted Q-learning approach using parametric Q-function models and a semiparametric missingness propensity model has recently been proposed. However, misspecification of…

连续处理下随机对象结局因果效应的双重稳健估计AI 解读

Causal inference is central to statistics and scientific discovery, enabling researchers to identify cause-and-effect relationships beyond associations. While traditionally studied within Euclidean spaces, contemporary applications increasingly involve complex, non-Euclidean data structures that reside in abstract metric spaces, known as random objects, such as images, shapes, networks, and distributions. This paper introduces a novel framework for causal inference with…

异质性下网络荟萃分析中节点的贝叶斯非参数合并与拆分AI 解读

Network meta-analysis (NMA) synthesizes evidence for multiple treatments, but decisions on node formation can have important statistical implications including bias or inflated uncertainty. Existing data-driven methods often lack flexibility or fail to fully account for node uncertainty and adjust for between-trial heterogeneity simultaneously. We introduce a Bayesian non-parametric framework using a Dirichlet process prior with a regularized horseshoe base measure. This…

暴露与混杂变量不完整时的平均因果效应估计AI 解读

Standard methods for estimating average causal effects require complete observations of the exposure and confounders. In observational studies, however, missing data are ubiquitous. Motivated by a study on the effect of prescription opioids on mortality, we propose methods for estimating average causal effects when exposures and potential confounders may be missing. We consider missingness at random and additionally propose several specific missing not at random (MNAR)…

通过条件独立关系以多项式延迟检验含隐变量的因果模型AI 解读

Testing a hypothesized causal model against observational data is a key prerequisite for many causal inference tasks. A natural approach is to test whether the conditional independence relations (CIs) assumed in the model hold in the data. While a model can assume exponentially many CIs (with respect to the number of variables), testing all of them is both impractical and unnecessary. Causal graphs, which encode these CIs in polynomial space, give rise to local Markov…

半竞争风险的贝叶斯非参数方法及心血管健康应用AI 解读

We address causal estimation in semi-competing risks settings, where a non-terminal event may be precluded by one or more terminal events. We define a principal-stratification causal estimand for treatment effects on the non-terminal event, conditional on surviving past a specified landmark time. To estimate joint event-time distributions, we employ both vine-copula constructions and Bayesian nonparametric Enriched Dirichlet-process mixtures (EDPM), enabling inference under…

未知方差高斯模型中的L2范数后验收缩AI 解读

The testing-based approach is a fundamental tool for establishing posterior contraction rates. Although the Hellinger metric is attractive owing to the existence of a desirable test function, it is not directly applicable in Gaussian models, because translating the Hellinger metric into more intuitive metrics typically requires strong boundedness conditions. When the variance is known, this issue can be addressed by directly constructing a test function relative to the $L_2$-…

密集纵向数据的动态因果中介分析AI 解读

Intensive longitudinal data, characterized by frequent measurements across numerous time points, are increasingly common due to advances in wearable devices and mobile health technologies. We consider evaluating causal mediation pathways between time-varying exposures, time-varying mediators, and a final, distal outcome using such data. Addressing mediation questions in these settings is challenging due to numerous potential exposures, complex mediation pathways, and…

结合可观测特征的单指标分位数因子模型AI 解读

We propose a characteristics-augmented quantile factor (QCF) model, where unknown factor loading functions are linked to a large set of observed individual-level (e.g., bond- or stock-specific) covariates via a single-index projection. The single-index specification offers a parsimonious, interpretable, and statistically efficient way to nonparametrically characterize the time-varying loadings, while avoiding the curse of dimensionality in flexible nonparametric models.…

异质性、不确定性与学习：半参数识别和估计AI 解读

We provide identification results for a broad class of learning models in which continuous outcomes depend on three types of unobservables: known heterogeneity, initially unknown heterogeneity that may be revealed over time, and transitory uncertainty. We consider a common environment where the researcher only has access to a short panel on choices and realized outcomes. We establish identification of the outcome equation parameters and the distribution of the unobservables,…

干扰程度：存在干扰时因果推断的一般框架AI 解读

One core assumption typically adopted for valid causal inference is that of no interference between experimental units, i.e., the outcome of an experimental unit is unaffected by the treatments assigned to other experimental units. This assumption can be violated in real-life experiments, which significantly complicates the task of causal inference. As the number of potential outcomes increases, it becomes challenging to disentangle direct treatment effects from…

利用特异性进行观察研究中的因果推断AI 解读

Hill's specificity criterion has been highly influential in biomedical and epidemiological research. However, it remains controversial and its application often relies on subjective and qualitative analysis without a comprehensive and rigorous causal theory. Focusing on unmeasured confounding adjustment with multiple treatments and multiple outcomes, this paper develops a formal and quantitative framework for leveraging specificity for causal inference in observational…

利用外部对照提高随机试验累积发生率估计的精度AI 解读

Augmenting the control arm in clinical trials with external data can improve statistical power for demonstrating treatment effects. In many time-to-event outcome trials, participants are subject to truncation by death. Direct application of methods for competing risks analysis on the joint data may introduce bias, for example, due to covariate shifts between the populations. In this work, we consider transportability of the conditional cause-specific hazard of the event of…

算子中核学习的极小极大收敛速率AI 解读

Learning kernels in operators from data lies at the intersection of inverse problems and statistical learning, providing a powerful framework for capturing non-local dependencies in function spaces and high-dimensional settings. In contrast to classical nonparametric regression, where the inverse problem is well-posed, kernel estimation involves a compact normal operator and an ill-posed deconvolution. To address these challenges, we introduce adaptive spectral Sobolev…

高效的双重差分与事件研究估计量AI 解读

This paper investigates efficient Difference-in-Differences (DiD) and Event Study (ES) estimation using short panel data sets within the heterogeneous treatment effect framework, free from parametric functional form assumptions and allowing for variation in treatment timing. We provide an equivalent characterization of the DiD potential outcome model using sequential conditional moment restrictions on observables, which shows that the DiD identification assumptions typically…

高适应Lasso隐含工作模型中的正则化目标最大似然估计AI 解读

We address the challenge of performing Targeted Maximum Likelihood Estimation (TMLE) after an initial Highly Adaptive Lasso (HAL) fit. Existing approaches that utilize the data-adaptive working model selected by HAL-such as the relaxed HAL update-can be simple and versatile but may become computationally unstable when the HAL basis expansions introduce collinearity. Undersmoothed HAL may fail to solve the efficient influence curve (EIC) at the desired level without…

结构非线性时间序列模型的脉冲响应分析AI 解读

This paper proposes a semiparametric sieve approach to estimate impulse response functions of nonlinear time series within a general class of structural autoregressive models. We prove that a two-step procedure can flexibly accommodate nonlinear specifications while avoiding the need to choose fixed parametric forms. Sieve impulse responses are proven to be consistent by deriving uniform estimation guarantees, and an iterative algorithm makes it straightforward to compute…