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Power-Dominance in Estimation Theory: A Third Pathological Axis

估计理论中的功效主导:第三条病态轴

This paper introduces a novel framework for estimation theory by introducing a second-order diagnostic for estimator design. While classical analysis focuses on the bias-variance trade-off, we present a more foundational constraint. This result is model-agnostic, domain-agnostic, and is valid for both parametric and non-parametric problems, Bayesian and frequentist frameworks. We propose to classify the estimators into three primary power regimes. We theoretically establish…

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Semiparametrics via parametrics and contiguity

通过参数模型与相邻性开展半参数推断

Inference on the parametric part of a semiparametric model is no trivial task. If one approximates the infinite dimensional part of the semiparametric model by a parametric function, one obtains a parametric model that is in some sense close to the semiparametric model and inference may proceed by the method of maximum likelihood. Under regularity conditions, the ensuing maximum likelihood estimator is asymptotically normal and efficient in the approximating parametric…

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Bayesian Semi-supervised Inference via a Debiased Modeling Approach

基于去偏建模的贝叶斯半监督推断

Inference in semi-supervised (SS) settings has gained substantial attention in recent years due to increased relevance in modern big-data problems. In a typical SS setting, there is a much larger-sized unlabeled data, containing only observations of predictors, and a moderately sized labeled data containing observations for both an outcome and the set of predictors. Such data naturally arises when the outcome, unlike the predictors, is costly or difficult to obtain. One of…

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Kernel Ridge Regression with Predicted Feature Inputs and Applications to Factor-Based Nonparametric Regression

带预测特征输入的核岭回归及其在因子型非参数回归中的应用

Kernel methods, particularly kernel ridge regression (KRR), are time-proven, powerful nonparametric regression techniques known for their rich capacity, analytical simplicity, and computational tractability. The analysis of their predictive performance has received continuous attention for more than two decades. However, in many modern regression problems where the feature inputs used in KRR cannot be directly observed and must instead be inferred from other measurements,…

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Quasi Instrumental Variable Methods for Stable Hidden Confounding and Binary Outcome

稳定隐性混杂与二元结果的准工具变量方法

Instrumental variable (IV) methods are central to causal inference from observational data, particularly when a randomized experiment is not feasible. However, of the three conventional core IV identification conditions, only one, IV relevance, is empirically verifiable; often one or both of the other conditions, exclusion restriction and IV independence from unmeasured confounders, are unmet in real-world applications. These challenges are compounded when the outcome is…

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Rate doubly robust estimation for weighted average treatment effects

加权平均处理效应的速率双重稳健估计

The weighted average treatment effect (WATE) defines a versatile class of causal estimands for populations characterized by propensity score weights, including the average treatment effect (ATE), treatment effect on the treated (ATT), on controls (ATC), and for the overlap population (ATO). WATE has broad applicability in social and medical research, as many datasets from these fields align with its framework. However, the literature lacks a systematic investigation into the…

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Semiparametric principal stratification analysis beyond monotonicity

超越单调性假设的半参数主分层分析

Intercurrent events, common in clinical trials and observational studies, affect the existence or interpretation of final outcomes. Principal stratification addresses this challenge by defining local average treatment effect estimands within subpopulations, but often relies on restrictive assumptions such as monotonicity and counterfactual intermediate independence. To overcome these limitations, we propose a semiparametric framework for principal stratification analysis…

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Inference on the Distribution of Individual Treatment Effects in Nonseparable Triangular Models

非可分三角模型中个体处理效应分布的推断

In this paper, we develop inference methods for the distribution of heterogeneous individual treatment effects (ITEs) in the nonseparable triangular model with a binary endogenous treatment and a binary instrument of Vuong and Xu (2017) and Feng, Vuong, and Xu (2019). We focus on the estimation of the cumulative distribution function (CDF) of the ITE, which can be used to address a wide range of practically important questions such as inference on the proportion of…

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A Review of Statistical Methods for Handling Nonignorable Missing Data using Instrument Approach

利用工具变量处理不可忽略缺失数据的统计方法综述

Nonignorable missing data, where the probability of missingness depends on unobserved values, presents a significant challenge in statistical analysis. Traditional methods often rely on strong parametric assumptions that are difficult to verify and may lead to biased estimates if misspecified. Recent advances have introduced the concept of a nonresponse instrument or shadow variable as a powerful tool to enhance model identifiability without requiring full parametric…

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Canonical correlation analysis of stochastic trends via functional approximation

通过函数逼近对随机趋势进行典型相关分析

This paper proposes a novel approach for semiparametric inference on the number $s$ of common trends and their loading matrix $ψ$ in $I(1)/I(0)$ systems. It combines functional approximation of limits of random walks and canonical correlations analysis, performed between the $p$ observed time series of length $T$ and the first $K$ discretized elements of an $L^2$ basis. Tests and selection criteria on $s$, and estimators and tests on $ψ$ are proposed; their properties are…

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Time-Varying Heterogeneous Treatment Effects in Event Studies

事件研究中的时变异质性处理效应

This paper examines the identification and estimation of heterogeneous treatment effects in event studies, emphasizing the importance of both lagged dependent variables and treatment effect heterogeneity. We show that omitting lagged dependent variables can induce omitted variable bias in the estimated time-varying treatment effects. We develop a novel semiparametric approach based on a short-T dynamic linear panel model with correlated random coefficients, where the…

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Variable Selection for Additive Global Fréchet Regression

加性全局Fréchet回归的变量选择

We present a novel framework for variable selection in Fréchet regression with responses in general metric spaces, a setting increasingly relevant for analyzing non-Euclidean data such as probability distributions and covariance matrices. Building on the concept of (weak) Fréchet conditional means, we develop an additive regression model that represents the metric-based discrepancy of the response as a sum of covariate-specific nonlinear functions in reproducing kernel…

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Identification and estimation of mediational effects of longitudinal modified treatment policies

纵向修正处理政策的中介效应识别与估计

We demonstrate a comprehensive semiparametric approach to causal mediation analysis, addressing the complexities inherent in settings with longitudinal and continuous treatments, confounders, and mediators. Our methodology utilizes a nonparametric structural equation model and a cross-fitted sequential regression technique based on doubly robust pseudo-outcomes, yielding an efficient, asymptotically normal estimator without relying on restrictive parametric modeling…

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Minimax optimal transfer learning for high-dimensional additive regression

高维可加回归的极小极大最优迁移学习

This paper studies high-dimensional additive regression under the transfer learning framework, where one observes samples from a target population together with auxiliary samples from different but potentially related regression models. We first introduce a target-only estimation procedure based on the smooth backfitting estimator with local linear smoothing. In contrast to previous work, we establish general error bounds under sub-Weibull($α$) noise, thereby accommodating…

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Identification of Partial-Differential-Equations-Based Models from Noisy Data via Splines

基于样条从噪声数据中识别偏微分方程模型

We propose a two-stage method called \textit{Spline Assisted Partial Differential Equation based Model Identification (SAPDEMI)} to identify partial differential equation (PDE)-based models from noisy data. In the first stage, we employ the cubic splines to estimate unobservable derivatives. The underlying PDE is based on a subset of these derivatives. This stage is computationally efficient: its computational complexity is a product of a constant with the sample size; this…

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Semiparametric Triple Difference Estimators

半参数三重差分估计量

The triple difference causal inference framework is an extension of the well-known difference-in-differences framework. It relaxes the parallel trends assumption of the difference-in-differences framework through leveraging data from an auxiliary domain. Despite being commonly applied in empirical research, the triple difference framework has received relatively limited attention in the statistics literature. Specifically, investigating the intricacies of identification and…

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Two-Stage Least Squares Instrumental Variable Estimation for Semiparametric Accelerated Failure Time Models with Right-Censored Data

右删失数据下半参数加速失效时间模型的两阶段最小二乘工具变量估计

Instrumental variable (IV) analysis is widely used in fields such as economics and epidemiology to address unobserved confounding and measurement error when estimating the causal effects of intermediate covariates on outcomes. However, extending the commonly used two-stage least squares (TSLS) approach to survival settings is nontrivial due to censoring. This paper introduces a novel extension of TSLS to the semiparametric accelerated failure time (AFT) model with…

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Regression Discontinuity Design with Spillovers

存在溢出效应的断点回归设计

This paper studies regression discontinuity designs (RDD) when linear-in-means spillovers occur between units that are close in their running variable. We show that the RDD estimand depends on the ratio of two terms: (1) the radius over which spillovers occur and (2) the choice of bandwidth used for the local linear regression. RDD estimates direct treatment effect when radius is of larger order than the bandwidth and total treatment effect when radius is of smaller order…

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Semiparametric sensitivity analysis: unmeasured confounding in observational studies

半参数敏感性分析:观察性研究中的未测量混杂

Establishing cause-effect relationships from observational data often relies on untestable assumptions. It is crucial to know whether, and to what extent, the conclusions drawn from non-experimental studies are robust to potential unmeasured confounding. In this paper, we focus on the average causal effect (ACE) as our target of inference. We generalize the sensitivity analysis approach developed by Robins et al. (2000), Franks et al. (2020), and Zhou and Yao (2023). We use…

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Network Meta-Analysis of survival outcomes with non-proportional hazards using flexible M-splines

利用灵活 M 样条处理非比例风险的生存结局网络荟萃分析

Network meta-analysis (NMA) is widely used in healthcare decision-making, where estimates of the effect of multiple treatments on outcomes are required. For time-to-event outcomes such as survival or disease progression the most common approach is to model log hazard ratios; however, this relies on the proportional hazards assumption. Novel treatments such as immunotherapies are expected to display complex hazard functions that cannot be captured by standard parametric…

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Average Causal Effect Estimation in DAGs with Hidden Variables: Beyond Back-Door and Front-Door Criteria

隐变量 DAG 中的平均因果效应估计:超越后门与前门准则

The identification theory for causal effects in directed acyclic graphs (DAGs) with hidden variables is well established, but methods for estimating and inferring functionals that extend beyond the g-formula remain underdeveloped. Previous studies have introduced semiparametric estimators for such functionals in a broad class of DAGs with hidden variables. While these estimators exhibit desirable statistical properties such as double robustness in certain cases, they also…

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Variance Estimation for Weighted Average Treatment Effects

加权平均处理效应的方差估计

Common variance estimation methods for weighted average treatment effects (WATEs) in observational studies include nonparametric bootstrap and model-based, closed-form sandwich variance estimation. However, the computational cost of bootstrap increases with the size of the data at hand. Besides, some replicates may exhibit random violations of the positivity assumption even when the original data do not. Sandwich variance estimation relies on regularity conditions that may…

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Improving the Estimation of Lifetime Effects in A/B Testing via Treatment Locality

利用处理局部性改进 A/B 测试中的终身效应估计

Utilizing randomized experiments to evaluate the effect of short-term treatments on the short-term outcomes has been well understood and become the golden standard in industrial practice. However, as service systems become increasingly dynamical and personalized, much focus is shifting toward maximizing long-term outcomes, such as customer lifetime value, through lifetime exposure to interventions. Our goal is to assess the impact of treatment and control policies on…

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Nonparametric Envelopes for Flexible Response Reduction

灵活响应降维的非参数包络方法

Envelope methods improve the estimation efficiency in multivariate linear regression by identifying and separating the material and immaterial parts of the responses or the predictors and estimating the regression coefficients using only the material part. Though envelopes have been extended to other models, such as GLMs, these extensions still largely fall under the restrictive parametric modeling framework. In this paper, we introduce a flexible, nonparametric extension of…

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