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Proximal Mediation Analysis with Unmeasured Treatment-Induced Confounding

存在未测量处理诱发混杂的近端中介分析

Mediation analysis provides a central framework for elucidating causal mechanisms, yet its application is often impeded by treatment-induced confounding, under which the widely used natural mediation effects are generally unidentifiable. Interventional effects have been proposed as an alternative when these confounders are observable; however, identifying and estimating interventional effects remains challenging when confounders are unmeasured. In this paper, we address this…

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Kernel Density Estimation by Spectral Decomposition: Data-Driven Tapering and Superposition

基于谱分解的核密度估计:数据驱动窗与叠加方法

Kernel density estimation depends largely on one choice, the smoothing bandwidth. We treat bandwidth selection and density estimation in the characteristic-function domain, where the cyclic group-averaged covariance of the binned data has the squared empirical characteristic function as its spectrum: the true characteristic function sits over a sampling-noise floor of $1/n$, and the bandwidth is the spectral cutoff where the two meet. Several methods follow. An automatic…

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A Mean Field Approach to Empirical Bayes Estimation in High-dimensional Linear Regression

高维线性回归经验贝叶斯估计的均值场方法

We study empirical Bayes estimation in high-dimensional linear regression. To facilitate computationally efficient estimation of the underlying prior, we adopt a variational empirical Bayes approach, introduced originally in Carbonetto and Stephens (2012) and Kim et al. (2022). We establish asymptotic consistency of the nonparametric maximum likelihood estimator (NPMLE) and its (computable) naive mean field variational surrogate under mild assumptions on the design and the…

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Propensity Score Propagation: A General Framework for Design-Based Inference with Unknown Propensity Scores

倾向得分传播:未知倾向得分下基于设计的推断框架

Design-based inference, also known as randomization-based or finite-population inference, provides a principled framework for trustworthy statistical inference. It attributes randomness solely to the design mechanism, such as treatment assignment, survey sampling, or missingness, without imposing super-population distributional or modeling assumptions on the outcome data. From the seminal work of Fisher and Neyman to its recent resurgence, design-based inference has played a…

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Semiparametric Efficiency in Sequential Experiments: Characterization and Design via Average Propensity

序贯实验的半参数效率:基于平均倾向得分的刻画与设计

Modern experiments, including evaluations of AI-enabled services and platform interventions, often depart from independent and identically distributed (i.i.d.) sampling because assignments may be adaptive, balanced across covariates, or subject to rollout constraints such as exposure, fairness, and budget limits. This paper studies the efficiency benchmark for estimating causal targets in such sequential experiments. We show that every non-anticipating design induces an…

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An Instrumental Variable Approach to Account for Informative Treatment Switching in Real-world Evidence

真实世界证据中信息性治疗切换的工具变量方法

Reproducible and generalizable assessment of treatment decisions requires principled handling of subsequent treatment switching that may inform expected outcomes and shift across cohorts and over time. To effectively account for informative treatment switching, we propose an instrumental variable approach that characterizes the poorly documented expected outcomes at switching as unmeasured confounding. After establishing the baseline treatment as a viable instrumental…

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A Uniform Confidence Band for the Marginal Treatment Effect Function

边际处理效应函数的一致置信带

This paper presents a method for constructing uniform confidence bands for the marginal treatment effect (MTE) function. The shape of the MTE function provides insight into how the unobserved propensity to receive treatment relates to the treatment effect. Our approach visualizes the statistical uncertainty of an estimated function, facilitating inferences about the function's shape. The proposed method is computationally inexpensive and requires only minimal information:…

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Quantile regression with measurement errors

含测量误差的分位数回归

We devise a novel estimator for a general quantile regression model with normal measurement errors in the covariates. The method is applicable to both linear and nonlinear quantile regressions and does not impose the quantile requirement on multiple quantile levels simultaneously. We circumvent the difficulties caused by discontinuity in quantile regression through kernel smoothing, and overcome the nonlinearity inherent in quantile regression via considering extension to…

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Similarity-Based Prediction for Digital Twins: Panel Data, Theory, and Applications

数字孪生的相似性预测:面板数据、理论与应用

Prediction from sequential panel data is central to digital-twin modeling, where new panels arrive over time and the predictive system is updated sequentially. Existing methods often rely on temporal proximity, which can fail when similar input-output patterns recur at nonadjacent times or when recent panels differ from the target panel. We propose State-Local Prediction (StaLoP), a nonparametric dynamic panel prediction framework that utilizes information through…

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Coarsening Bias from Variable Discretization in Causal Functionals

因果泛函中变量离散化导致的粗化偏差

Causal identification functionals often require integration over conditional densities of continuous variables, such as those arising in nonparametric identification theory of total and mediated causal effects in DAGs with hidden variables. Estimating these densities and evaluating the resulting integrals can be statistically and computationally demanding. A common workaround is to discretize the continuous variable and replace integrals with finite sums. Although…

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Censored broken adaptive ridge rank regression via induced smoothing

基于诱导平滑的删失断崖自适应岭秩回归

Broken adaptive ridge (BAR) penalty approximates $L_0$-regularization through iterative reweighting of L2 penalties. This penalty enjoys both the oracle property and the grouping effect for highly correlated covariates, making it particularly attractive for penalized regression with complex dependence among predictors. In this paper, we develop a BAR-penalized linear rank regression method for the semiparametric accelerated failure time model with right-censored data.…

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A causal modeling perspective on decision theory

从因果建模视角看决策理论

Decision theory provides a formal framework for how agents should make choices under uncertainty, drawing on ideas from philosophy, probability, and causality. Despite significant progress, the field still lacks a unified modeling language, and key concepts - such as the distinction between subjective and objective elements, or what it means for a decision theory to perform well - are often left implicit. This can make it difficult to evaluate and compare competing theories,…

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Learning Preferences from Conjoint Data: A Hybrid Structural Deep Learning Approach

从联合分析数据学习偏好:结构模型与深度学习的混合方法

Conjoint experiments randomize multidimensional profiles, yet political science applications typically report only nonparametric averages that do not recover counterfactual choices or individual tradeoffs. We develop a hybrid structural approach for recovering individual preferences from conjoint data. The estimator combines a flexible machine-learning mean preference function, via a deep netural network in our applications, with respondent-level empirical-Bayes updating in…

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Multiply Robust Causal Mediation Analysis with Continuous Treatments

连续处理下的多重稳健因果中介分析

In many applications, researchers are interested in the direct and indirect causal effects of a treatment or exposure on an outcome of interest. Mediation analysis offers a rigorous framework for identifying and estimating these causal effects. For binary treatments, efficient estimators for the direct and indirect effects are presented by Tchetgen Tchetgen and Shpitser (2012) based on the influence function of the parameter of interest. These estimators possess desirable…

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Valuation Reveals Uncertainty

估值揭示不确定性

This paper studies the recovery of uncertainty from dynamic sublinear valuation rules. A robust valuation assigns each payoff its worst-case expected value across plausible models under uncertainty and induces a dynamic sublinear valuation rule. While valuation rules are observable in practice, the underlying uncertainty structure is latent. First, we show that the latent uncertainty structure can be identified from an observed valuation rule and provide an explicit…

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Falsifying Discriminant Validity of Predictive Algorithms

预测算法区分效度的证伪检验

Empirical investigations into unintended model behavior often show that the algorithm is predicting another outcome than what was intended. These exposés highlight the need to identify when algorithms predict unintended quantities - ideally before deploying them into consequential settings. We propose a falsification framework that provides a principled statistical test for discriminant validity: the requirement that an algorithm predict intended outcomes better than…

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Uniform Estimation and Inference for Nonparametric Partitioning-Based M-Estimators

非参数分割型 M 估计的一致估计与统一推断

This paper presents uniform estimation and inference theory for a large class of nonparametric partitioning-based M-estimators. The main theoretical results include: (i) uniform consistency for convex and non-convex objective functions; (ii) rate-optimal uniform Bahadur representations; (iii) rate-optimal uniform (and mean square) convergence rates; (iv) valid strong approximations and feasible uniform inference methods; and (v) extensions to functional transformations of…

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Inferring Comprehensive Cohort Causal Effects in the Presence of Unmeasured Confounding and Missing Outcomes

未测混杂与结局缺失下的综合队列因果效应推断

This paper presents a methodological framework for estimating the comprehensive cohort causal effect (CCCE) in mixed-design clinical studies that combine randomized controlled trials (RCTs) and parallel observational study (OBS). Our approach is designed to evaluate robustness against unmeasured confounding in the OBS arm and to handle outcomes that are missing at random in either the RCT or OBS arm. By employing a semiparametric theory-based sensitivity analysis framework,…

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Spatio-temporal model via Locally Adaptive Regression Splines

基于局部自适应回归样条的时空模型

This paper focuses on the estimation of a non-parametric regression function in the presence of data with spatio-temporal dependencies. In such a context, we study Locally Adaptive Regression Splines, a nonparametric estimator introduced by Mammen and Van De Geer (1997) and Rudin et al. (1992). To the best of our knowledge, this estimator has not previously been examined in a similar context. For univariate settings, the signals we consider are assumed to have a kth weak…

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Choosing the threshold in extreme value analysis

极值分析中的阈值选择

One of the two dominant approaches for univariate extreme value analysis is to model exceedances above a large threshold, the choice of which has a large impact on inference and whose uncertainty is often subsequently ignored. In this article we review more than 40 threshold selection procedures, including semiparametric methods based on Hill's estimator, visual diagnostics, goodness-of-fit tests, and others based on extended generalized Pareto models. Starting with the…

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Tree-Embedded Bayesian Factor Models for Multidimensional Categorical Distributions

多维分类分布的树嵌入贝叶斯因子模型

Analyzing data collected from multiple observational units to estimate common and heterogeneous structures through a hierarchical model is a central task in Bayesian inference, and to this end, Bayesian factor models are one of the most widely used tools for this purpose. In this paper, we propose a novel Bayesian latent factor model for categorical distributions from grouped data, providing a parsimonious model for describing many observed distributions through…

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Robust and Scalable Sure Screening of Fixed effects in Ultrahigh-dimensional Linear Mixed Models

超高维线性混合模型中固定效应的稳健可扩展确信筛选

In modern applications of linear mixed models, the number of candidate fixed-effects covariates can grow exponentially with the sample size, while dependence induced by random effects and possible data contamination pose substantial challenges for existing variable screening methods. We propose a robust and computationally efficient sure screening procedure for identifying relevant fixed-effects covariates in ultrahigh-dimensional linear mixed models with known random…

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Semiparametric Off-Policy Inference for Optimal Policy Values under Possible Non-Uniqueness

最优策略可能不唯一时的半参数离策略价值推断

Off-policy evaluation (OPE) constructs confidence intervals for the value of a target policy using data generated under a different behavior policy. Most existing inference methods focus on fixed target policies and may fail when the target policy is estimated as optimal, particularly when the optimal policy is non-unique or nearly deterministic. We study inference for the value of optimal policies in Markov decision processes. In an auxiliary augmented transition-sampling…

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Causal Inference with the Napkin Graph

Napkin 因果图下的因果推断

Unmeasured confounding can render identification strategies based on adjustment functionals invalid. We study the "Napkin" graph, a causal structure that encapsulates features of M-bias, instrumental variables, and classical back-door and front-door settings, yet identifies the average treatment effect through a nonstandard ratio of two g-formulas. We develop influence-function-based estimators for this functional, including doubly-robust one-step and targeted minimum…

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