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Proximal Identification and Estimation in Front-Door Causal Structures with Unobserved Confounding of the Mediator

中介存在未观测混杂的前门因果结构:近端识别与估计

Unobserved confounding is a fundamental obstacle in causal inference problems. In the graphical modeling literature, a general theory has been developed that allows identification in the presence of hidden variables, with some limitations. In particular, Pearl's celebrated front-door criterion allows nonparametric identification in the presence of unobserved common causes of the treatment and the outcome, however it requires the presence of an unconfounded variable that…

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Semiparametric Bayesian structure learning of nonparanormal directed acyclic graphs with local--global shrinkage

采用局部—全局收缩的非正态变换有向无环图半参数贝叶斯结构学习

Bayesian structure learning of directed acyclic graphs (DAGs) is central to high-dimensional causal discovery, yet existing methods mostly assume multivariate Gaussian data, which is routinely violated by measurements displaying heavy tails, skewness, or bounded support. We address this by introducing NPN-DAG-HS, a fully Bayesian semiparametric DAG model coupling the nonparanormal family with horseshoe shrinkage on Cholesky off-diagonals via an extended-rank likelihood. This…

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Denoising Data with Measurement Error Using a Reproducing Kernel-based Diffusion Model

基于再生核扩散模型的测量误差数据去噪

The ongoing technological revolution in measurement systems enables the acquisition of high-resolution samples in fields such as engineering, biology, and medicine. However, these observations are often subject to errors from measurement devices. Motivated by this challenge, we propose a denoising framework that employs diffusion models to generate denoised data whose distribution closely approximates the unobservable, error-free data, thereby permitting standard data…

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Deep Gaussian Processes on Directed Acyclic Graphs

有向无环图上的深度高斯过程

Many real-world processes can be represented as compositions of functions along a directed acyclic graph (DAG). In causal modelling, these correspond to the underlying mechanisms; in engineering, to multiple fidelity levels; and in gene-regulatory networks, to transcription factors. These functions are partially observed across the DAG, with noisy and heterogeneously sampled measurements, posing significant challenges for reconstruction, uncertainty propagation, and…

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Local Gaussian Correlation in the Tails: A Scarcity Diagnostic, an Optimal Local Bandwidth, and the Limits of Adaptivity

尾部局部高斯相关:样本稀缺诊断、最优局部带宽与适应性的边界

Local Gaussian correlation (LGC) measures dependence locally, making it a natural tool for tail dependence and financial contagion, but its estimates degrade in the joint tails, where they are most needed. Location-adaptive bandwidths have been tried for LGC and found inferior to a single global bandwidth; we explain why, and map the regime in which adaptivity does help. First, a diagnostic: across heavy-tailed data-generating processes the parametric marginal pre-transform…

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Robust Weighted Triangulation of Causal Effects Under Model Uncertainty

模型不确定性下因果效应的稳健加权三角验证

A fundamental challenge in causal inference with observational data is correct specification of a causal model. When there is model uncertainty, analysts may seek to use estimates from multiple candidate models that rely on distinct, and possibly partially overlapping, sets of identifying assumptions to infer the causal effect, a process known as triangulation. Principled methods for triangulation, however, remain underdeveloped. Here, we develop a framework for causal…

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Model-robust standardization in stepped wedge cluster randomized trials

阶梯楔形集群随机试验中的模型稳健标准化

Stepped-wedge cluster-randomized trials (SW-CRTs) are widely used in healthcare and implementation science, enabling all clusters to receive the intervention through a staggered rollout. Traditional model-based methods, including generalized estimating equations and mixed models, yield estimates that depend on implicit weighting schemes and parametric assumptions, and therefore may target ambiguous estimands under model misspecification. In this article, we propose a…

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Multivariate Bayesian P-spline estimation of spectral density matrices, with application to LISA TDI noise

谱密度矩阵的多元贝叶斯 P 样条估计及 LISA TDI 噪声应用

We present a Bayesian P-spline method for estimating the frequency-dependent cross-spectral density matrix of stationary multivariate time series. The inverse spectral matrix is parametrised through its frequency-varying Cholesky decomposition, which guarantees Hermitian positive definiteness at every frequency. Each real log-diagonal entry and each real and imaginary off-diagonal entry is given an independent penalised B-spline prior that controls smoothness. Inference uses…

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Doubly cross-fit debiased machine learning of heterogeneous treatment effects under principal stratification

主分层下异质性处理效应的双重交叉拟合去偏机器学习

Principal stratification provides a foundational framework for causal inference with intermediate outcomes by defining causal effects within subpopulations, yet existing work has largely focused on average effects across strata rather than treatment effect heterogeneity within strata. Such within-stratum heterogeneity informs individualized treatment decisions but the associated methods are sparse. We address this gap by studying the identification and estimation of the…

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MAPLE: Mapper Based Localized Prediction with Data Driven Cover Selection for High dimensional Data

MAPLE:基于 Mapper 的局部预测与数据驱动覆盖选择

High dimensional biomedical data often exhibit nonlinear, heterogeneous, and manifold driven structures that challenge global parametric and tree-based models. We propose MAPLE (mapper-based Adaptive Prediction via Local Estimation), a localized prediction framework grounded in topological data analysis. The method is formulated as a nonparametric estimator of conditional class probabilities that adapts to the intrinsic geometry of the predictor space. Neighborhoods are…

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tsbootstrap: Distribution-Free Uncertainty Quantification and Conformal Prediction for Time Series

tsbootstrap:时间序列的分布无关不确定性量化与保形预测

Finance, sensing, and demand streams violate the exchangeability that IID conformal prediction and the IID bootstrap assume, and existing libraries implement either a general resampling engine or conformal calibration without the other. tsbootstrap provides block, residual, sieve, and wild resampling, classical bootstrap confidence intervals, and adaptive conformal calibrators (EnbPI, ACI, NexCP, AgACI) through a single typed API in which a specification object selects each…

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Embracing Spillover: Spatial Effects in Experiments

正视溢出:实验中的空间效应

Interventions delivered in space generate effects that spill over between experimental units. We develop a framework for spatial experiments in which causal estimands, inclduing direct, indirect, total, and dose--response effects, are linear functionals of a spillover kernel. Under cluster randomisation with a fixed exposure set size, the data identify the shape of the kernel but not its level: the level is aliased with the intercept and direct effect, at any sample size and…

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Statistical inference for the probability of necessity for causal attribution

因果归因中必要性概率的统计推断

To answer questions of "causes of effects", the probability of necessity was previously introduced for assessing whether an observed outcome was caused by an earlier treatment. However, statistical inference for the probability of necessity is understudied due to several difficulties, which hinder its application in practice. The evaluation of the probability of necessity involves the joint distribution of potential outcomes, and thus it is generally not point identified and…

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A Machine-Learning-Compatible Omnibus Test for Treatment Effect Heterogeneity

兼容机器学习的处理效应异质性综合检验

This study proposes a formal, computationally efficient nonparametric omnibus test for treatment-effect heterogeneity that is compatible with a broad class of estimators, including modern machine-learning methods. The test is designed for settings in which identification can rely on high-dimensional controls while heterogeneity is assessed with respect to a low-dimensional subset of covariates. We derive the test statistic's asymptotic null distribution and develop a…

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Approximate Risk Minimization Over Shrinking-Thresholding Rules in Normal Mean Estimation

正态均值估计中收缩阈值规则的近似风险最小化

We develop an approximate risk minimization framework for shrinkage-thresholding estimation in normal mean problems. In the canonical multivariate normal mean model, we introduce a general functional class of estimators that contains classical shrinkage and thresholding behavior, including James-Stein-type and lasso-type rules. We express quadratic risk as a functional over this class, derive optimality conditions for both oracle risk and data-driven approximate risk…

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Semiparametric Efficiency Theory as Differential Calculus on a Space of Probability Distributions

半参数效率理论:概率分布空间上的微分学

Semiparametric efficiency theory provides the mathematical foundation for influence-function-based estimation, including one-step estimators, targeted minimum loss estimators, and many modern inferential methods used in causal inference and missing data analysis. Despite its widespread use, the theory is often presented through a collection of technical constructions whose geometric meaning remains opaque. As a result, influence functions are often derived and applied…

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Optimal Designs with Robust Inference for Binary Treatment Effects

二元结局处理效应的最优实验设计与稳健推断

We study randomized experiments with binary outcomes under Neyman's nonparametric model, where covariate measurements are fixed but potential outcomes are random. In this setting we derive the exact variance of the difference-in-means estimator and characterize designs that minimize it. We show that any balanced design satisfying a covariate-balance condition is asymptotically optimal, and we prove that a broad class of blocking designs satisfies this condition under mild…

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Non-Asymptotic Analysis of Classical Spectrum Estimators for $L$-mixing Time-series Data with Estimated Means

均值需估计时 L-mixing 时间序列经典谱估计量的非渐近分析

Spectral estimation is an important tool in time series analysis, with applications including economics, astronomy, and climatology. The asymptotic theory for non-parametric estimation is well-known but the development of non-asymptotic theory is still ongoing. Our recent work obtained the first non-asymptotic error bounds on the Bartlett and Welch methods with restrictive assumptions. In this work, we derive non-asymptotic error bounds for both Bartlett and Welch estimators…

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Smooth Reduced Rank Regression with P-splines

基于P样条的平滑降秩回归

Linear regression is one of the core statistical tools used for analysis of data. In the era of statistical learning, linear regression has been expanded into two directions. The first is regularisation, where penalties are added to the loss function to obtain more stable or sparse solutions. The second direction is basis expansion, such as with spline or kernel functions, where the linearity assumption is dropped. In practice, empirical researchers often collect multiple…

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Uniform inference for kernel instrumental variable regression

核工具变量回归的一致推断

Instrumental variable regression is a foundational tool for causal analysis across the social and biomedical sciences. Recent advances use kernel methods to estimate nonparametric causal relationships, with general data types, while retaining a simple closed-form expression. Empirical researchers ultimately need reliable inference on causal estimates; however, uniform confidence sets for the method remain unavailable. To fill this gap, we develop valid and sharp confidence…

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Minimum Density Power Divergence Estimation for the Gamma Distribution with Applications to Robust Rainfall Modeling

伽马分布的最小密度幂散度估计及其在稳健降雨建模中的应用

Statistical modeling of rainfall amounts is of considerable importance in meteorology, hydrology, and agriculture. The gamma distribution remains one of the most popular choices for modeling rainfall data due to its flexibility and ability to capture the skewness of rainfall observations. Rainfall datasets often contain atypical observations due to measurement errors and extreme weather events, making maximum likelihood estimation (MLE) highly sensitive to contamination. In…

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Two-way Clustering Robust Variance Estimator in Quantile Regression Models

分位数回归模型中的双向聚类稳健方差估计

We study inference for linear quantile regression with two-way clustered data. Using a separately exchangeable array framework and a projection decomposition of the quantile score, we characterize regime-dependent convergence rates and establish a self-normalized Gaussian approximation. We propose a two-way cluster-robust sandwich variance estimator with a kernel-based density ``bread'' and a projection-matched ``meat'', and prove consistency and validity of inference in…

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Targeted Highly Adaptive Lasso Minimum Loss Estimation of Target Functions

目标函数的目标化高度自适应Lasso最小损失估计

We propose a Targeted Highly Adaptive Lasso for estimation of non-pathwise differentiable functional parameters such as the dose-response curve (DRC) for continuous exposure. We assume the target function lies in the $k$-th order smoothness class used to define the $k$-th order Highly Adaptive Lasso (HAL), which can be well approximated by linear spans of $k$-th order spline basis functions. We construct a projection of the true target function onto a large finite…

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Cross-Fitted Survey-Weighted TMLE with Design-Based Variance for Causal Machine Learning

具有设计型方差的交叉拟合调查加权 TMLE

Cross-fitting is not a refinement of survey-weighted causal machine learning but, once the nuisances are flexible, what restores valid inference. We study the population average treatment effect under a stratified multistage design, estimated by a survey-aware targeted maximum likelihood estimator (TMLE) whose variance is obtained by Taylor-series linearization of the influence function, treating the primary sampling unit as the replication unit. Our central result is that…

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