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利用协变量注释信息提高 Knockoff 变量选择的功效AI 解读

Genome-wide association studies (GWAS) often find association signals between many genetic variants and traits of interest in a genomic region. Functional annotations of these variants provide valuable prior information that helps prioritize biologically relevant variants and enhances the power to detect causal variants. However, due to substantial correlations among these variants, a critical question is how to rigorously control the false discovery rate while effectively…

利用代理 p 值与 e 值的主动多重检验AI 解读

Researchers often lack the resources to test every hypothesis of interest directly or compute test statistics comprehensively, but often possess auxiliary data from which we can compute an estimate of the experimental outcome. We introduce a novel approach for selecting which hypotheses to query a statistic (e.g., run an experiment, perform expensive computation, etc.) in a hypothesis testing setup by leveraging estimates to compute proxy statistics. Our framework allows a…

二元分类与政策价值的非参数一致推断AI 解读

We develop methods for nonparametric uniform inference in cost-sensitive binary classification, a framework that encompasses maximum score estimation, predicting utility maximizing actions, and policy learning. These problems are well known for slow convergence rates and non-standard limiting behavior, even under point identified parametric frameworks. In nonparametric settings, they may further suffer from failures of identification. To address these challenges, we…

结合双重／去偏机器学习的连续处理双重差分AI 解读

This paper extends difference-in-differences to settings with continuous treatments. Specifically, the average treatment effect on the treated (ATT) at any level of treatment intensity is identified under a conditional parallel trends assumption. Estimating the ATT in this framework requires first estimating infinite-dimensional nuisance parameters, particularly the conditional density of the continuous treatment, which can introduce substantial bias. To address this…

点过程强度函数的孪生核估计：基于轨道正则性的自适应非参数方法AI 解读

We develop TwinKernel methods for nonparametric estimation of intensity functions of point processes. Building on the general TwinKernel framework and combining it with martingale techniques for counting processes, we construct estimators that adapt to orbital regularity of the intensity function. Given a point process $N$ with intensity $λ$ and a cyclic group $G = \langle\varphi\rangle$ acting on the time/space domain, we transport kernels along group orbits to create a…

打开黑箱：新加坡 GDP 增长的即时预测与可解释性AI 解读

Timely assessment of current conditions is essential especially for small, open economies such as Singapore, where external shocks transmit rapidly to domestic activity. We develop a real-time nowcasting framework for quarterly GDP growth using a high-dimensional panel of approximately 70 indicators, encompassing economic and financial indicators over 1990Q1-2023Q2. The analysis covers penalized regressions, dimensionality-reduction methods, ensemble learning algorithms, and…

乘法测量误差下的拟合优度检验AI 解读

Given observations from a positive random variable contaminated by multiplicative measurement error, we consider a nonparametric goodness-of-fit testing task for its unknown density in a non-asymptotic framework. We propose a testing procedure based on estimating a quadratic functional of the Mellin transform of the unknown density and the null. We derive non-asymptotic testing radii and testing rates over Mellin-Sobolev spaces, which naturally characterize regularity and…

宏观与金融即时预测中的可解释机器学习：面向商业与政策决策的框架AI 解读

Macroeconomic nowcasting sits at the intersection of traditional econometrics, data-rich information systems, and AI applications in business, economics, and policy. Machine learning (ML) methods are increasingly used to nowcast quarterly GDP growth, but adoption in high-stakes settings requires that predictive accuracy be matched by interpretability and robust uncertainty quantification. This article reviews recent developments in macroeconomic nowcasting and compares…

在控制错误发现率下识别分布差异AI 解读

We consider the problem of comparing a reference distribution with several other distributions. Given a sample from both the reference and the comparison groups, we aim to identify the comparison groups whose distributions differ from that of the reference group. Viewing this as a multiple testing problem, we introduce a methodology that provides exact, distribution-free control of the false discovery rate. To do so, we introduce the concept of batch conformal p-values and…

尖锐回归折点设计中局部处理效应识别与推断的统一框架AI 解读

This paper develops a unified framework for the identification, estimation, and uniform inference of local treatment effects (LTEs) in sharp regression kink designs (RKDs). These LTEs quantify the effect of a marginal change in the treatment at the kink point on various features of the outcome distribution. The identification strategy applies to Hadamard-differentiable functionals of the outcome distribution -- including means, quantiles, and inequality measures -- and…

样本量依赖核的高维U统计量高斯近似AI 解读

Motivated by small bandwidth asymptotics for kernel-based semiparametric estimators in econometrics, this paper establishes Gaussian approximation results for high-dimensional fixed-order $U$-statistics whose kernels depend on the sample size. Our results allow for a situation where the dominant component of the Hoeffding decomposition is absent or unknown, including cases with known degrees of degeneracy as special forms. The obtained error bounds for Gaussian…

引用网络的双向共因子分析AI 解读

One compelling use of citation networks is to characterize papers by their relationships to the surrounding literature. We propose a method to characterize papers by embedding them into two distinct "co-factor" spaces: one describing how papers send citations, and the other describing how papers receive citations. This approach presents several challenges. First, older documents cannot cite newer documents, and thus it is not clear that co-factors are even identifiable. We…

强化学习数据收集后的统计推断AI 解读

We study estimation and inference using data collected by reinforcement learning (RL) algorithms. These algorithms adaptively experiment by interacting with individual units over multiple stages, updating their strategies based on past outcomes. Our goal is to evaluate a counterfactual policy after data collection and estimate structural parameters, such as dynamic treatment effects, that support credit assignment and quantify the impact of early actions on final outcomes.…

超越疾病研究：用倾斜 knockoffs 控制次级表型变量选择AI 解读

Researchers in biomedical studies often work with samples that are not selected uniformly at random from the population of interest, a major example being a case-control study. While these designs are motivated by specific scientific questions, it is often of interest to use the data collected to pursue secondary lines of investigations. In these cases, ignoring the fact that observations are not sampled uniformly at random can lead to spurious results. For example, in a…

零膨胀单细胞 RNA 测序数据的共同中介统计框架AI 解读

Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of cellular heterogeneity, enabling detailed molecular profiling at the individual cell level. However, integrating high-dimensional single-cell data into causal mediation analysis remains challenging due to zero inflation and complex mediator structures. We propose a novel mediation framework leveraging zero-inflated negative binomial models to characterize cell-level mediator distributions and beta…

非可分三角模型中个体处理效应分布的推断AI 解读

In this paper, we develop inference methods for the distribution of heterogeneous individual treatment effects (ITEs) in the nonseparable triangular model with a binary endogenous treatment and a binary instrument of Vuong and Xu (2017) and Feng, Vuong, and Xu (2019). We focus on the estimation of the cumulative distribution function (CDF) of the ITE, which can be used to address a wide range of practically important questions such as inference on the proportion of…

高维门槛回归模型中的一致推断AI 解读

We develop a uniform inference theory for high-dimensional slope parameters in threshold regression models, allowing for either cross-sectional or time series data. We first establish oracle inequalities for prediction errors, and L1 estimation errors for the Lasso estimator of the slope parameters and the threshold parameter, accommodating heteroskedastic non-subgaussian error terms and non-subgaussian covariates. Next, we derive the asymptotic distribution of tests…

政策学习中最优福利的置信下界AI 解读

We study inference on the optimal welfare in a policy learning problem and propose reporting a lower confidence band (LCB). A natural approach to constructing an LCB is to invert a one-sided t-test based on an efficient estimator for the optimal welfare. However, we show that for an empirically relevant class of DGPs, such an LCB can be first-order dominated by an LCB based on a welfare estimate for a suitable suboptimal treatment policy. We show that such first-order…

通用机器学习子群识别的统计性能保证AI 解读

Across a wide array of disciplines, many researchers use machine learning (ML) algorithms to identify a subgroup of individuals who are likely to benefit from a treatment the most (``exceptional responders'') or those who are harmed by it. A common approach to this subgroup identification problem consists of two steps. First, researchers estimate the conditional average treatment effect (CATE) using an ML algorithm. Next, they use the estimated CATE to select those…

利用多重检验进行奇异谱分析分组AI 解读

A key step in separating signal from noise in time series by means of singular spectrum analysis (SSA) is grouping. We present a multiple testing method for the grouping step in SSA. As separability criterion, we utilize the weighted correlation between the signal and the noise component of the (reconstructed) time series, and we test whether this weighted correlation is equal to zero. This test has to be performed for several possible groupings, resulting in a multiple test…

复杂时间动态下单调平滑时变函数的同时推断AI 解读

We propose a new framework for the simultaneous inference of monotone and smoothly time-varying functions under complex temporal dynamics. This will be done utilizing the monotone rearrangement and the nonparametric estimation. We capitalize the Gaussian approximation for the nonparametric monotone estimator and construct the asymptotically correct simultaneous confidence bands (SCBs) using designed bootstrap methods. We investigate two general and practical scenarios. The…

函数型因子回归及其在电价曲线建模中的应用AI 解读

We propose a function-on-function linear regression model for time-dependent curve data that is consistently estimated by imposing factor structures on the regressors. An integral operator based on cross-covariances identifies two components for each functional regressor: a predictive low-dimensional component, along with associated factors that are guaranteed to be correlated with the dependent variable, and an infinite-dimensional component that has no predictive power. In…

停止时e-BH程序的任意时点有效错误发现率控制AI 解读

The recent e-Benjamini-Hochberg (e-BH) procedure for multiple hypothesis testing is known to control the false discovery rate (FDR) under arbitrary dependence between the input e-values. This paper points out an important subtlety when applying the e-BH procedure with e-processes, which are sequential generalizations of e-values (where the data are observed sequentially). Since adaptively stopped e-processes are e-values, the e-BH procedure can be repeatedly applied at every…

超越 Bonferroni：实证研究中的层级多重检验AI 解读

Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni correction, control the family-wise error rate (FWER) but tend to be overly conservative, reducing statistical power. Stepwise alternatives like the Holm and Hochberg procedures offer improved power while maintaining error control under certain…