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A Grid-Rate Condition for Valid Uniform Inference

有效一致推断的网格增长速率条件

Conducting uniform inference on a continuous functional F defined on a compact subset X of R^d involves specifying L_n^d nodes for estimation and the construction of confidence bands. While asymptotically valid inference requires L_n to increase with n, existing fixed-L rules of thumb and heuristic data-driven approaches lack formal justification. This paper shows that, for functions within a Donsker class, the simple grid-growth condition r_n^(1/4)/L_n -> 0, equivalently…

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Powerful Multivariate Sensitivity Analysis via Sample Splitting in an Observational Study of the Effects of Poverty on Cardiovascular Disease Risk Factors

通过样本分割增强多变量敏感性分析:贫困与心血管疾病风险因素

When assessing the causal effect of an exposure on two or more outcomes in an observational study, a linear combination of outcomes may lessen the sensitivity of a test of the global null hypothesis to potential unmeasured biases. While all linear combinations of scored outcomes can be considered using Scheffe projections or constrained variants thereof, finding the combination that minimizes sensitivity to unmeasured biases requires corrections for multiple testing, which…

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Network knockoffs: controlling false discovery in dyadic space

网络 knockoffs:在二元空间中控制错误发现

Phenomena such as epidemiological processes, hydrologic systems, social platforms, utility services, and supply chains can be represented as topological networks. A central question about these networks concerns connectivity and the permeability of edges. Dyadic regression and related approaches have been proposed to identify network features associated with pairwise node-level differences. In high-dimensional settings, it is important to control the number of spuriously…

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Estimating Effects of Longitudinal Modified Treatment Policies (LMTPs) on Rates of Change in Health Outcomes

纵向修正治疗政策对健康结局变化率的效应估计

Longitudinal data often contains outcomes measured at multiple visits, and scientific interest may lie in quantifying the effect of an intervention on an outcome's rate of change. For example, one may wish to study the progression (or trajectory) of a disease over time under different hypothetical interventions. We extend the longitudinal modified treatment policy (LMTP) methodology to estimate effects of complex, exposure-dependent interventions on rates of change in an…

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Semiparametric Inference for Causal Effects on Functional Outcomes

函数型结局因果效应的半参数推断

Difference-in-differences (DiD) is a cornerstone of causal inference, yet extending it to functional outcomes is not a routine scalar generalization; rather, it entails three fundamental challenges in identification, inference, and observation. This paper develops a comprehensive semiparametric inference framework for functional DiD with discretely observed data. First, we define the functional average treatment effect under parallel trends and derive its efficient influence…

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rd2d: Causal Inference in Boundary Discontinuity Designs

rd2d:边界断点设计中的因果推断软件

Boundary Discontinuity (BD) designs are used in empirical research to learn about causal treatment effects along a continuous assignment boundary defined by a bivariate score. These designs are also known as multi-score regression discontinuity (RD) designs, and include geographic RD designs as a prominent example. This article introduces \pkg{rd2d}, a statistical software package for \proglang{R}, \proglang{Python}, and \proglang{Stata} that implements local polynomial…

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IV regression with distribution-valued outcomes

分布值结局的工具变量回归

We develop IV Fréchet regression (IVFR), an instrumental-variable (IV) method for settings where the outcome is an entire distribution. Framing the problem as an IV regression in 2-Wasserstein space, IVFR extends global Fréchet regression to the case with endogenous covariates. IVFR projects IV-weighted quantile curves onto the space of valid distributions and then recovers the corresponding regression coefficient functions. The projection provably reduces the estimation…

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Quantile and Distribution Treatment Effects on the Treated with Possibly Non-Continuous Outcomes

可能非连续结局下处理组的分位数与分布处理效应

Applied Difference-in-Differences studies often involve outcomes that are discrete, mixed, censored, or otherwise non-continuously distributed, while policy questions frequently concern distributional effects rather than mean effects alone. This paper develops a distributional DiD framework for identifying and conducting uniform inference on distribution and quantile treatment effects on the treated in such settings under stated identifying and regularity conditions.…

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Quasi-Bayesian Local Projections: Simultaneous Inference and Extension to the Instrumental Variable Method

准贝叶斯局部投影:同时推断及工具变量扩展

Local projections (LPs) are widely used for impulse response analysis, but Bayesian methods face challenges due to the absence of a likelihood function. Existing approaches rely on pseudo-likelihoods, which often result in poorly calibrated posteriors. We propose a quasi-Bayesian method based on the Laplace-type estimator, where a quasi-likelihood is constructed using a generalized method of moments criterion. This approach avoids strict distributional assumptions, ensures…

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Controlling False Discovery in Arbitrarily Structured Hypothesis Spaces via Reproducing Kernels

用再生核控制任意结构假设空间中的错误发现

Large-scale hypothesis testing is central to modern science, where controlling the False Discovery Rate (FDR) has become the standard approach to managing false positives across many simultaneous tests. Hypotheses rarely exist in isolation; they often exhibit structure through proximity, connectivity, or hierarchy. This structure represents both a challenge and an opportunity: while classical methods treat these dependencies as obstacles requiring conservative correction,…

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Causal Discovery via Statistical Power (CDSP)

通过统计功效进行因果发现

Causal discovery methods aim to infer causal direction from observational data. Functional causal discovery approaches use structural asymmetries to identify causal directionality but rely on strong modeling assumptions and provide limited tools for uncertainty quantification. We introduce Causal Discovery via Statistical Power (CDSP), a statistical inference framework that connects causal direction estimation with statistical power and enables uncertainty quantification.…

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Informative Simultaneous Confidence Intervals for Graphical Group Sequential Test Procedures

图形化群序贯检验的信息性同时置信区间

Test procedures for multiple hypotheses in a group sequential clinical trial that control the family-wise error rate are considered. Several graphical group sequential tests suggested in the literature, which are special cases of Bonferroni-closure tests, are discussed. The focus is on the question of whether to consider at the current stage only the evidence of the current repeated p-value or the evidence over all repeated p-values from the previous stages. A new test…

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Causal inference with ordinal outcomes: copula-based identification, estimation and sensitivity analysis

有序结果的因果推断:基于 Copula 的识别、估计与敏感性分析

In causal inference with ordinal outcomes, several interpretable estimands are functions of the probability that the potential outcome under one treatment is larger than that under another treatment for the same unit. This probability depends on the joint distribution of both potential outcomes and is generally not identifiable. Existing work has focused on sharp bounds of this probability based on partial identification, but bounds are often too wide to be informative. We…

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Adaptive discovery of effect modification in matched observational studies

匹配观察研究中效应修饰的自适应发现

Understanding effect modification -- how treatment effects vary across subpopulations -- is practically important in observational studies, as it helps identify which subgroups are likely to benefit from a given treatment. In this paper, we study the discovery of effect modification in matched observational studies, where each treated unit may be matched to multiple controls. We develop a finite-sample valid procedure for identifying and selecting covariate-interpretable…

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A joint longitudinal-survival framework for dynamic treatment regimen evaluation in sequential multiple assignment randomized trials

序贯多次随机分配试验中评估动态治疗方案的纵向—生存联合框架

Sequential multiple assignment randomized trials (SMARTs) provide a systematic framework for constructing and evaluating dynamic treatment regimens (DTRs). In clinical studies, longitudinal biomarkers are routinely collected to monitor disease progression and define treatment response. However, the integration of longitudinal biomarker data into survival analysis for DTR evaluation within a SMART remains unexplored. We propose a joint longitudinal-survival framework to…

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Simultaneous Inference for Nonlinear Time Series, a Sieve M-regression Approach

非线性时间序列的同时推断:筛法 M 回归方法

This paper studies simultaneous inference of conditional distributions in nonlinear time series from a sieve M-regression perspective. Existing literature on sieve M-regression has primarily focused on pointwise asymptotics, leaving the development of uncertainty quantification over the entire predictor space unexplored. We address this gap by establishing a uniform Bahadur representation for the sieve M-estimator, accommodating dependent data and a growing number of sieve…

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High-dimensional linear regression inference via $\ell^2$ weak convergence

高维线性回归推断:基于 ℓ² 弱收敛

We prove weak convergence in a separable Hilbert space for estimators of high-dimensional regression coefficients, which yields asymptotic normality and enables direct use of standard asymptotic tools such as the continuous mapping theorem. The approach permits diverging sparsity with many small nonzero coefficients, while requiring that only finitely many have moderate magnitude. As applications, we develop a test for finitely many linear hypotheses and, via a Scheffé-type…

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Efficient Longitudinal Function-on-Function Regression

纵向函数对函数回归的高效推断

We propose a computationally efficient inferential procedure for longitudinal function-on-function regression. The method follows a marginal three-step approach: (1) fit massive pointwise longitudinal scalar-on-function regression models, (2) smooth the resulting estimates along the bivariate functional domain, and (3) compute confidence bands using either an analytic approach for Gaussian data or a cluster bootstrap for Gaussian or non-Gaussian data. Simulation studies…

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Nonparametric Testing and Variable Selection for ARCH-m(X) Model

ARCH-m(X) 模型的非参数检验与变量选择

We introduce the ARCH-m(X) model, a semiparametric extension of the ARCH-X framework in which the effect of a multivariate exogenous covariate vector X on the conditional variance is modeled through an unknown nonparametric function m(), accommodating complex nonlinear relationships between external predictors and financial volatility. Within this model, we develop a novel hypothesis test for the significance of covariates constructed with an artificial one-way ANOVA. Under…

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Consistent Variable Selection for GARCH-X Models

GARCH-X 模型的一致变量选择

In this paper we develop a consistent variable selection procedure for GARCH-X models that identifies the truly relevant exogenous covariates influencing volatility dynamics. The proposed method is based on a multiple hypothesis testing framework with Wald-type test statistics and the Benjamini-Yekutieli False Discovery Rate (FDR) procedure to control the proportion of false discoveries. We establish the consistency of the selection rule, showing that it asymptotically…

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Density-valued VAR Models with Latent Factors

含潜在因子的密度值向量自回归模型

We propose a density-valued vector autoregressive model with latent factors for multivariate time series of density functions. Motivated by weekly regional distributions of SARS-CoV-2 cycle threshold (Ct) values in Brazil, we study their distributional dynamics across regions. The Ct value is the number of amplification cycles required for the viral signal to cross a detection threshold (lower Ct values correspond to higher viral load). We estimate each regional density by a…

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Simultaneous Inference for Time Series Functional Linear Regression

时间序列函数型线性回归的同时推断

We consider the problem of joint simultaneous confidence band (JSCB) construction for regression coefficient functions of time series scalar-on-function linear regression when the regression model is estimated by roughness penalization approach with flexible choices of orthonormal basis functions. A simple and unified multiplier bootstrap methodology is proposed for the JSCB construction which is shown to achieve the correct coverage probability asymptotically. Furthermore,…

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Bi-Gaussian Mirrors for False Discovery Rate Control

双高斯镜像方法用于错误发现率控制

Effectively controlling the false discovery rate (FDR) in high-dimensional variable selection is a fundamental statistical problem that has garnered significant research interest. In this paper, we propose a novel, user-friendly, and computationally efficient method called Bi-Gaussian Mirrors (BGM), which offers a conceptually simple yet powerful approach for FDR control. Our method makes the first attempt to achieve FDR control in high-dimensional data with complex…

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Simultaneous Inference for Covariance and Precision Matrices of Long-Range Dependent Time Series

长程依赖时间序列协方差矩阵与精度矩阵的同时推断

For time series with long-range temporal dependence, inference for covariance and precision matrices is non-trivial. We propose a Berry-Esseen type Gaussian approximation result that gives a finite-sample bound for the Kolmogorov distance between the infinity norms of the estimation error of sample covariance matrix and the corresponding Gaussian approximation. The method utilizes martingale and m-dependent approximation and relies on constructing triadic blocks. We also…

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