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Bayesian hierarchical bootstrap framework for causal subgroup estimation with a time-to-event outcome

事件时间结果因果亚组估计的贝叶斯层级自助框架

Causal estimation of treatment effects within prespecified subgroups, such as biomarker-defined strata, disease phenotypes, or demographic groups are often of clinical interest. Bayesian approaches are attractive for subgroup effect estimation because flexible priors can represent complex treatment heterogeneity and propagate posterior uncertainty. Frequentist methods for prespecified causal subgroup analysis with time-to-event outcomes are also available, including…

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OT-FairBoost: Optimal Transport-Guided Gradient Boosting for Fairness Regularization on Tabular Data

OT-FairBoost:最优传输引导的梯度提升表格数据公平性正则化

Although neural-based machine learning models have received a lot of attention recently, tree-based models such as gradient boosting are competitive for tabular data and therefore remain widely used in various applications of AI. As when using other machine learning predictive models, they can however yield discriminative predictions across demographic groups, due to so-called algorithmic biases. These undesirable phenomena have motivated the emergence of new regulatory…

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Debiased Machine Learning: Identification, Estimation, and Shape Constraints

去偏机器学习:识别、估计与形状约束

We develop a general framework of identification and estimation for automatic debiased machine learning (DML) where the parameter of interest $θ_0$ is identified by a moment condition involving a nuisance $γ_0$ that may be high dimensional. We establish conditions under which the Riesz representer $α_0$, which is at the core of DML, is identified, and show that the identification occurs precisely when $α_0$ uniquely optimizes a quadratic functional. This characterization…

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Towards Best Practices for Covariate Adjustment in Regulatory Trials: From Fixed to Data-Adaptive Approaches

监管试验协变量调整的良好实践:从固定到数据自适应方法

While randomization justifies the use of unadjusted effect estimators in randomized trials, there is growing interest in covariate adjustment to improve precision. Adjusting for baseline variables that are prognostic of the outcome can reduce estimator variance, resulting in narrower confidence intervals and increased statistical power. Recent guidance by the U.S. Food and Drug Administration supports fixed adjustment for prognostic covariates using parametric regression…

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Heterogeneous Treatment Effect Estimation under Noncompliance in the Illinois Workplace Wellness Study with Bayesian Tree Ensembles

贝叶斯树集成估计不依从下的异质性效应:伊利诺伊职场健康研究

Estimating varying treatment effects in randomized trials with noncompliance is inherently challenging since variation comes from two separate sources: variation in the impact itself and variation in the compliance rate. In this setting, existing flexible machine learning methods are sensitive to the weak instruments problem and can yield unstable estimates of heterogeneity when run repeatedly with different initialization or random seeds. Our main methodological…

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On the use of cross-fitting in causal machine learning with correlated units

相关观测单位下因果机器学习的交叉拟合

In causal machine learning, the fitting and evaluation of nuisance models are often performed on separate partitions, or folds, of the observed data. This technique, called cross-fitting, eliminates bias introduced by the use of black-box predictive algorithms. When study units may be correlated, such as in spatial, clustered, or time-series data, investigators often design bespoke forms of cross-fitting to minimize correlation between folds. We prove that, perhaps contrary…

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The positivity assumption in causal mediation analyses? Checked!

因果中介分析中的正值性假设检查

Causal mediation analyses are increasingly used in psychological sciences. Among the required assumptions, positivity is unfortunately seldom mentioned, likely due to the lack of tools for checking it. Mediational positivity is more complex than positivity in standard, non-mediated exposure effect analysis, because it requires positivity for both the exposure and the mediator, and because the specific form of the positivity assumption depends on the mediation estimand of…

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MOCA: A Transformer-based Modular Causal Inference Framework with One-way Cross-attention and Cutting Feedback

MOCA:采用单向交叉注意力与反馈切断的模块化因果推断框架

Causal effect estimation from observational data requires careful adjustment for confounding. Classical estimators such as inverse probability weighting and augmented inverse probability weighting can perform well under favorable model specification but may become unstable in complex settings. Machine-learning and representation-learning methods provide greater flexibility, but joint optimization may allow outcome information to alter treatment representations and compromise…

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A Bayesian Additive Regression Tree Model for Learning Conditional Average Treatment Effects in Regression Discontinuity Designs

利用贝叶斯加性回归树估计断点回归中的条件平均处理效应

This paper develops an effective Bayesian approach to conditional average treatment effect (CATE) estimation in regression discontinuity designs (RDD), an increasingly prevalent form of quasi-experiment that facilitates causal inference. Earlier Bayesian approaches do not easily accommodate CATE estimation while recent frequentist approaches to this problem assume a known basis expansion, a steep model specification requirement that our approach avoids. The new model is a…

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Attenuated Heterogeneity in Fixed-Effects Causal Forests, and a Cross-Fitted Correction

固定效应因果森林中的异质性衰减及交叉拟合校正

Causal forests that estimate conditional average treatment effects by averaging honest leaf-level effects across trees are widely used in fixed-effects panel settings. We show that this averaging systematically attenuates the estimated heterogeneity: the raw prediction behaves like a + b*tau(x) with slope b < 1, so the spread of the CATEs is compressed toward the average effect, and the additive recentering used to report an unbiased average treatment effect does not fix it.…

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Nonlinear Boosting with Multiple Testing in High-Dimensional Generalised Linear Models with Binary Responses

高维二元响应广义线性模型中的多重检验非线性提升

This paper proposes a nonlinear boosting with multiple testing (BMT) approach to variable selection in high-dimensional generalised linear models with binary responses. At each stage of the BMT procedure, the model is updated by adding only the most significant covariate, conditional on those already selected in previous stages, while taking into account the multiple testing nature of the problem. It is shown that, under the stated conditions, the BMT procedure selects all…

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Learning Bidirectional Causal Interactions with Heteroscedastic Neural Networks

利用异方差神经网络学习双向因果交互

Estimating contemporaneous bidirectional interactions from observational data is difficult because each outcome is endogenous to the other, while flexible regressions may capture only reduced-form dependence. This paper proposes SEM-DNN, a heteroscedastic neural simultaneous-equation estimator that learns reciprocal structural interactions without external instruments. Identification exploits conditional covariance diagonalization: when structural shocks have zero…

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GAUGER: Generalized Regression Adjustment via Graph-Weighted Exposure-Level Residualization for Design-Based Inference Under Interference

GAUGER:干扰下基于图加权暴露水平残差化的回归调整

Estimating causal effects under interference is a common problem in social science and economics. However, it is challenging due to the complex dependency structure induced by network connections. In this paper, we propose GAUGER, a Generalized regression Adjustment framework via Graph-weighted Exposure-level Residualization for design-based causal inference under general interference. We first reveal a surprising mismatch between accuracy and efficiency in this setting:…

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Automatic Debiased Machine Learning for Dynamic Treatment Effects and General Nested Functionals

动态处理效应与一般嵌套泛函的自动去偏机器学习

Many canonical models in causal inference and structural econometrics have recursive identification formulas. In causal inference, recursion arises when identification requires both pre- and post-treatment covariates. For example, short-term surrogate outcomes are measured after the treatment, and serve as necessary covariates when identifying long-term effects. Post-treatment covariates are also required for identification of dynamic difference-in-differences designs,…

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A Fixed-Effects Causal Forest for Staggered Adoption, with an Application to Medicaid Expansion

用于交错实施的固定效应因果森林及其医保扩张应用

Difference-in-differences with staggered adoption identifies group-time average treatment effects ATT(g,t) by comparing each cohort to units not yet treated, which avoids the "forbidden comparisons" that bias two-way fixed-effects estimators when effects are heterogeneous. This paper studies the covariate-conditional version of that object, tau_{g,t}(x), and estimates it with a fixed-effects causal forest. Within each (g,t) comparison block, the outcome and treatment are…

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Identification and Estimation of Optimal Continuous Treatment Effects

最优连续处理效应的识别与估计

Estimating continuous treatment effects is hard because average-derivative estimators rely on an ill-posed conditional-density score. Recent work makes a bounded outcome weight the primitive, characterizing a class of weighted average derivative effects without density estimation. In this paper, we develop the identification and estimation theory for the optimally efficient estimands of this class under homoskedasticity and heteroskedasticity. On identification, we show that…

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Neural Networks of Outcome Weighted Learning for Individualized Treatment Rules

用于个体化治疗规则的结局加权学习神经网络

Individualized treatment rules (ITRs) formalize precision medicine by assigning treatments according to patient covariates, with the goal of maximizing expected clinical outcomes. Such rules are especially important when treatment effects vary across patients, as in chronic diseases where demographic, clinical, genetic, imaging, or biomarker information may modify the relative benefits of available therapies. Individualized treatment rules (ITRs) formalize precision medicine…

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Frugal, Flexible, Faithful: Causal Data Simulation via Frengression

简约、灵活、忠实:通过 Frengression 模拟因果数据

Machine learning has revitalized causal inference by combining flexible models and principled estimators, yet robust benchmarking and evaluation remain challenging with real-world data. In this work, we introduce frengression, a deep generative realization of the frugal parameterization that models the joint distribution of covariates, treatments and outcomes around the causal margin of interest. Frengression provides accurate estimation and flexible, faithful simulation of…

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Minimax Theory of Likelihood-Based Deep Learning for Speckle Regression

基于似然的深度学习斑点回归的极小极大理论

Speckle noise is a multiplicative noise commonly encountered in coherent imaging modalities such as synthetic aperture radar, optical coherence tomography, and digital holography. Although deep learning methods, in practice, have achieved state-of-the-art performance for speckle denoising, their fundamental statistical limits remain largely unexplored. Unlike additive noise models, multiplicative speckle noise makes the regression function unidentifiable from the conditional…

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Difference-in-differences with stochastic policy shifts of a continuous treatment

连续处理随机政策变动下的双重差分

Treatment effects of stochastic policy shifts quantify differences in outcomes across counterfactual scenarios with varying treatment distributions. Stochastic policy shifts may be of interest in settings where it is unrealistic or infeasible to deterministically manipulate treatments. In this paper, methods are developed to draw inference about stochastic policy effects under difference-in-differences (DiD) designs with a continuous treatment. The proposed causal estimand…

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Order-Explicit Linearization of High-Dimensional $U$-Statistics

高维 U 统计量中显式依赖阶数的线性化

We give an order-explicit large deviation bound for the difference between a high-dimensional $U$-statistic and its Hájek projection. In particular, we show that any $U$-statistic of order $b$ on $n$ observations, with a $d$-dimensional kernel whose coordinates have $ψ_1$-Orlicz norm at most $φ$, has a maximum deviation from its Hájek projection of order $O_p(φb n^{-1}\log^2(dn))$. The proof relies on the development of novel order-explicit moment inequalities for…

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High-Dimensional Interpolators Can Be Fragile: Heavy Tails and High-Dimensional Large Deviations

高维插值器可能脆弱:重尾与高维大偏差

High-dimensional interpolation is common in modern machine learning, but its tail risk is less understood than its expected prediction risk. Existing theory shows that interpolating models can perform well in expectation, yet such guarantees do not determine the probability of rare, severe errors. In operations research and stochastic decision-making applications, rare estimation errors can have disproportionate downstream effects, so tail behavior matters alongside average…

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Modeling the Dynamic Relationship Between Brent Crude Oil Prices and the Nepal Stock Exchange: An Integrated Econometric and Explainable Machine Learning Approach

布伦特原油与尼泊尔股市的动态关系:计量与可解释机器学习

This study examines the dynamic relationship between the global oil prices and Nepal Stock Exchange (NEPSE) using an integrated approach which combines traditional econometric techniques with machine learning and explainable AI techniques. For this, Daily data of International Oil prices and NEPSE index is analyzed from approximately thirteen years (June 2013 to June 2026) using Granger causality, EGARCH(1,1), and DCC-GARCH models to examine different properties like…

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Bayesian Deep Learning for Discrete Choice

离散选择的贝叶斯深度学习

Discrete choice models (DCMs) are used to analyze individual decision-making in contexts such as transportation choices, political elections, and consumer preferences. DCMs play a central role in applied econometrics by enabling inference on key economic variables, such as marginal rates of substitution, rather than focusing solely on predicting choices on new unlabeled data. However, while traditional DCMs offer high interpretability and support for point and interval…

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