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Application of targeted maximum likelihood estimation in public health and epidemiological studies: a systematic review

目标最大似然估计在公共卫生与流行病学中的应用:系统综述

The Targeted Maximum Likelihood Estimation (TMLE) statistical data analysis framework integrates machine learning, statistical theory, and statistical inference to provide a least biased, efficient and robust strategy for estimation and inference of a variety of statistical and causal parameters. We describe and evaluate the epidemiological applications that have benefited from recent methodological developments. We conducted a systematic literature review in PubMed for…

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Educational Inequality of Opportunity and Mobility in Europe

欧洲教育机会不平等与代际流动

Educational attainment generates labor market returns, societal gains and has intrinsic value for individuals. We study Inequality of Opportunity (IOp) and intergenerational mobility in the distribution of educational attainment. We propose to use debiased IOp estimators based on the Gini coefficient and the Mean Logarithmic Deviation (MLD) which are robust to machine learning biases. We also measure the effect of each circumstance on IOp, we provide tests to compare IOp in…

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Censored Quantile Regression with Many Controls

含大量控制变量的删失分位数回归

This paper develops estimation and inference methods for censored quantile regression models with high-dimensional controls. The methods are based on the application of double/debiased machine learning (DML) framework to the censored quantile regression estimator of Buchinsky and Hahn (1998). I provide valid inference for low-dimensional parameters of interest in the presence of high-dimensional nuisance parameters when implementing machine learning estimators. The proposed…

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Estimating Heterogeneous Causal Mediation Effects with Bayesian Decision Tree Ensembles

利用贝叶斯决策树集成估计异质性因果中介效应

The causal inference literature has increasingly recognized that explicitly targeting treatment effect heterogeneity can lead to improved scientific understanding and policy recommendations. Towards the same ends, studying the causal pathway connecting the treatment to the outcome can be also useful. This paper addresses these problems in the context of \emph{causal mediation analysis}. We introduce a varying coefficient model based on Bayesian additive regression trees to…

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On the Provable Advantage of Unsupervised Pretraining

无监督预训练优势的可证明条件

Unsupervised pretraining, which learns a useful representation using a large amount of unlabeled data to facilitate the learning of downstream tasks, is a critical component of modern large-scale machine learning systems. Despite its tremendous empirical success, the rigorous theoretical understanding of why unsupervised pretraining generally helps remains rather limited -- most existing results are restricted to particular methods or approaches for unsupervised pretraining…

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Learning high-dimensional causal effect

高维因果效应学习

The scarcity of high-dimensional causal inference datasets restricts the exploration of complex deep models. In this work, we propose a method to generate a synthetic causal dataset that is high-dimensional. The synthetic data simulates a causal effect using the MNIST dataset with Bernoulli treatment values. This provides an opportunity to study varieties of models for causal effect estimation. We experiment on this dataset using Dragonnet architecture (Shi et al. (2019))…

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Nonparametric Conditional Local Independence Testing

非参数条件局部独立性检验

Conditional local independence is an asymmetric independence relation among continuous time stochastic processes. It describes whether the evolution of one process is directly influenced by another process given the histories of additional processes, and it is important for the description and learning of causal relations among processes. We develop a model-free framework for testing the hypothesis that a counting process is conditionally locally independent of another…

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Local Gaussian process extrapolation for BART models with applications to causal inference

BART 模型的局部高斯过程外推及因果推断应用

Bayesian additive regression trees (BART) is a semi-parametric regression model offering state-of-the-art performance on out-of-sample prediction. Despite this success, standard implementations of BART typically provide inaccurate prediction and overly narrow prediction intervals at points outside the range of the training data. This paper proposes a novel extrapolation strategy that grafts Gaussian processes to the leaf nodes in BART for predicting points outside the range…

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Patient stratification in multi-arm trials: a two-stage procedure with Bayesian profile regression

多臂试验中的患者分层:贝叶斯画像回归两阶段方法

Precision medicine is an emerging field that takes into account individual heterogeneity to inform better clinical practice. In clinical trials, the evaluation of treatment effect heterogeneity is an important component, and recently, many statistical methods have been proposed for stratifying patients into different subgroups based on such heterogeneity. However, the majority of existing methods developed for this purpose focus on the case with a dichotomous treatment and…

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The DeepCAR Method: Forecasting Time-Series Data That Have Change Points

DeepCAR:含变点时间序列的预测方法

Many methods for time-series forecasting are known in classical statistics, such as autoregression, moving averages, and exponential smoothing. The DeepAR framework is a novel, recent approach for time-series forecasting based on deep learning. DeepAR has shown very promising results already. However, time series often have change points, which can degrade the DeepAR's prediction performance substantially. This paper extends the DeepAR framework by detecting and including…

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A Meta-Reinforcement Learning Algorithm for Causal Discovery

用于因果发现的元强化学习算法

Causal discovery is a major task with the utmost importance for machine learning since causal structures can enable models to go beyond pure correlation-based inference and significantly boost their performance. However, finding causal structures from data poses a significant challenge both in computational effort and accuracy, let alone its impossibility without interventions in general. In this paper, we develop a meta-reinforcement learning algorithm that performs causal…

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Estimating Causal Effects Under Image Confounding Bias with an Application to Poverty in Africa

图像混杂偏差下的因果效应估计及非洲贫困应用

Observational studies of causal effects require adjustment for confounding factors. In the tabular setting, where these factors are well-defined, separate random variables, the effect of confounding is well understood. However, in public policy, ecology, and in medicine, decisions are often made in non-tabular settings, informed by patterns or objects detected in images (e.g., maps, satellite or tomography imagery). Using such imagery for causal inference presents an…

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CUTS: Neural Causal Discovery from Irregular Time-Series Data

CUTS:从不规则时间序列中进行神经网络因果发现

Causal discovery from time-series data has been a central task in machine learning. Recently, Granger causality inference is gaining momentum due to its good explainability and high compatibility with emerging deep neural networks. However, most existing methods assume structured input data and degenerate greatly when encountering data with randomly missing entries or non-uniform sampling frequencies, which hampers their applications in real scenarios. To address this issue,…

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Deep Neural Networks for Nonparametric Interaction Models with Diverging Dimension

维度增长下非参数交互模型的深度神经网络估计

Deep neural networks have achieved tremendous success due to their representation power and adaptation to low-dimensional structures. Their potential for estimating structured regression functions has been recently established in the literature. However, most of the studies require the input dimension to be fixed and consequently ignore the effect of dimension on the rate of convergence and hamper their applications to modern big data with high dimensionality. In this paper,…

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Robust Causal Graph Representation Learning against Confounding Effects

抵御混杂影响的稳健因果图表示学习

The prevailing graph neural network models have achieved significant progress in graph representation learning. However, in this paper, we uncover an ever-overlooked phenomenon: the pre-trained graph representation learning model tested with full graphs underperforms the model tested with well-pruned graphs. This observation reveals that there exist confounders in graphs, which may interfere with the model learning semantic information, and current graph representation…

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Minimax Instrumental Variable Regression and $L_2$ Convergence Guarantees without Identification or Closedness

无需唯一识别或闭合条件的极小极大工具变量回归及 L₂ 收敛保证

In this paper, we study nonparametric estimation of instrumental variable (IV) regressions. Recently, many flexible machine learning methods have been developed for instrumental variable estimation. However, these methods have at least one of the following limitations: (1) restricting the IV regression to be uniquely identified; (2) only obtaining estimation error rates in terms of pseudometrics (\emph{e.g.,} projected norm) rather than valid metrics (\emph{e.g.,} $L_2$ norm)…

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Reevaluating the Taylor Rule with Machine Learning

用机器学习重新评估泰勒规则

This paper aims to reevaluate the Taylor Rule, through a linear and a nonlinear method, such that its estimated federal funds rates match those actually previously implemented by the Federal Reserve Bank. In the linear method, this paper uses an OLS regression model to find more accurate coefficients within the same Taylor Rule equation in which the dependent variable is the federal funds rate, and the independent variables are the inflation rate, the inflation gap, and the…

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Distribution estimation and change-point estimation for time series via DNN-based GANs

基于深度神经网络 GAN 的时间序列分布估计与变点估计

The generative adversarial networks (GANs) have recently been applied to estimating the distribution of independent and identically distributed data, and have attracted a lot of research attention. In this paper, we use the blocking technique to demonstrate the effectiveness of GANs for estimating the distribution of stationary time series. Theoretically, we derive a non-asymptotic error bound for the Deep Neural Network (DNN)-based GANs estimator for the stationary…

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The mbsts package: Multivariate Bayesian Structural Time Series Models in R

mbsts 包:R 中的多变量贝叶斯结构时间序列模型

The multivariate Bayesian structural time series (MBSTS) model is a general machine learning model that deals with inference and prediction for multiple correlated time series, where one also has the choice of using a different candidate pool of contemporaneous predictors for each target series. The MBSTS model has wide applications and is ideal for feature selection, time series forecasting, nowcasting, inferring causal impact, and others. This paper demonstrates how to use…

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A Fast Bootstrap Algorithm for Causal Inference with Large Data

大规模数据因果推断的快速自助法算法

Estimating causal effects from large experimental and observational data has become increasingly prevalent in both industry and research. The bootstrap is an intuitive and powerful technique used to construct standard errors and confidence intervals of estimators. Its application however can be prohibitively demanding in settings involving large data. In addition, modern causal inference estimators based on machine learning and optimization techniques exacerbate the…

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Augmented Learning of Heterogeneous Treatment Effects via Gradient Boosting Trees

基于梯度提升树的异质性处理效应增广学习

Heterogeneous treatment effects (HTE) based on patients' genetic or clinical factors are of significant interest to precision medicine. Simultaneously modeling HTE and corresponding main effects for randomized clinical trials with high-dimensional predictive markers is challenging. Motivated by the modified covariates approach, we propose a two-stage statistical learning procedure for estimating HTE with optimal efficiency augmentation, generalizing to arbitrary interaction…

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A Machine Learning Approach to Measuring Climate Adaptation

用机器学习测量气候适应

I measure adaptation to climate change by comparing elasticities from short-run and long-run changes in damaging weather. I propose a debiased machine learning approach to flexibly measure these elasticities in panel settings. In a simulation exercise, I show that debiased machine learning has considerable benefits relative to standard machine learning or ordinary least squares, particularly in high-dimensional settings. I then measure adaptation to damaging heat exposure in…

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Causal Effect Estimation: Recent Advances, Challenges, and Opportunities

因果效应估计:近期进展、挑战与机会

Causal inference has numerous real-world applications in many domains, such as health care, marketing, political science, and online advertising. Treatment effect estimation, a fundamental problem in causal inference, has been extensively studied in statistics for decades. However, traditional treatment effect estimation methods may not well handle large-scale and high-dimensional heterogeneous data. In recent years, an emerging research direction has attracted increasing…

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Real Estate Property Valuation using Self-Supervised Vision Transformers

利用自监督视觉 Transformer 进行房地产估值

The use of Artificial Intelligence (AI) in the real estate market has been growing in recent years. In this paper, we propose a new method for property valuation that utilizes self-supervised vision transformers, a recent breakthrough in computer vision and deep learning. Our proposed algorithm uses a combination of machine learning, computer vision and hedonic pricing models trained on real estate data to estimate the value of a given property. We collected and…

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