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通过因子暴露映射对高维营养数据开展贝叶斯非参数因果推断AI 解读

Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces several challenges: (i) high-dimensional and correlated food/nutrient intake data induce massive treatment levels; (ii) nutritional studies are interested in latent dietary patterns rather than single food items; and (iii) the goal is to…

用平均导数效应参数化连续处理的影响AI 解读

The average treatment effect (ATE) is commonly used to quantify the main effect of a binary treatment on an outcome. Extensions to continuous treatments are usually based on the dose-response curve or shift interventions, but both require strong overlap conditions and the resulting curves may be difficult to summarise. We focus instead on average derivative effects (ADEs) that are scalar estimands related to infinitesimal shift interventions requiring only local overlap…

多结局整群随机试验中广义因果效应的最优估计AI 解读

Cluster-randomized trials (CRTs) are widely used to evaluate group-level interventions and increasingly collect multiple outcomes capturing complementary dimensions of benefit and risk. Investigators often seek a single global summary of treatment effect, yet existing methods largely focus on single-outcome estimands or rely on model-based procedures with unclear causal interpretation or limited robustness. We develop a unified potential outcomes framework for generalized…

稳健 X-Learner：用稳健交叉插补应对不平衡与厚尾AI 解读

Estimating Heterogeneous Treatment Effects (HTE) in industrial applications such as AdTech and healthcare presents a dual challenge: extreme class imbalance and heavy-tailed outcome distributions. While the X-Learner framework effectively addresses imbalance through cross-imputation, we demonstrate that it is fundamentally vulnerable to "Outlier Smearing" when reliant on Mean Squared Error (MSE) minimization. In this failure mode, the bias from a few extreme observations…

无岭最小二乘插值估计量的分布AI 解读

The Ridgeless minimum $\ell_2$-norm interpolator in overparametrized linear regression has attracted considerable attention in recent years in both machine learning and statistics communities. While it seems to defy conventional wisdom that overfitting leads to poor prediction, recent theoretical research on its $\ell_2$-type risks reveals that its norm minimizing property induces an `implicit regularization' that helps prediction in spite of interpolation. This paper takes…

基于组合多重子抽样的U学习：面向LASSO与神经网络的预测推断AI 解读

Epigenetic aging clocks play a pivotal role in estimating an individual's biological age through the examination of DNA methylation patterns at numerous CpG (Cytosine-phosphate-Guanine) sites within their genome. However, making valid inferences on predicted epigenetic ages, or more broadly, on predictions derived from high-dimensional inputs, presents challenges. We introduce a novel U-learning approach via combinatory multi-subsampling for making ensemble predictions and…

高维线性回归中良性过拟合的迁移学习AI 解读

Transfer learning is a key component of modern machine learning, enhancing the performance of target tasks by leveraging diverse data sources. Simultaneously, overparameterized models such as the minimum-$\ell_2$-norm interpolator (MNI) in high-dimensional linear regression have garnered significant attention for their remarkable generalization capabilities, a property known as benign overfitting. Despite their individual importance, the intersection of transfer learning and…

causalfe：带固定效应的因果森林 Python 实现AI 解读

The causalfe package provides a Python implementation of Causal Forests with Fixed Effects (CFFE) for estimating heterogeneous treatment effects in panel data settings. Standard causal forest methods struggle with panel data because unit and time fixed effects induce spurious heterogeneity in treatment effect estimates. The CFFE approach addresses this by performing node-level residualization during tree construction, removing fixed effects within each candidate split rather…

基于双重／去偏机器学习的时变连续处理双重差分AI 解读

We propose a difference-in-differences (DiD) framework designed for time-varying continuous treatments across multiple periods. Specifically, we estimate the average treatment effect on the treated (ATET) by comparing distinct non-zero treatment intensities. Identification rests on a conditional parallel trends assumption that accounts for observed covariates and past treatment histories. Our approach allows for lagged treatment effects and, in repeated cross-sectional…

样本选择模型的自动去偏机器学习与敏感性分析AI 解读

In this paper, we extend the Riesz representation framework to causal inference under sample selection, where both treatment assignment and outcome observability are non-random. Formulating the problem in terms of a Riesz representer enables stable estimation and a transparent decomposition of omitted variable bias into three interpretable components: a data-identified scale factor, outcome confounding strength, and selection confounding strength. For estimation, we employ…

协方差驱动的回归树：降低CART过拟合AI 解读

Decision trees are powerful machine learning algorithms, widely used in fields such as economics and medicine for their simplicity and interpretability. However, decision trees such as CART are prone to overfitting, especially when grown deep or the sample size is small. Conventional methods to reduce overfitting include pre-pruning and post-pruning, which constrain the growth of uninformative branches. In this paper, we propose a complementary approach by introducing a…

非参数二元选择模型的核化估计方法AI 解读

We propose a new estimator for nonparametric binary choice models that does not impose a parametric structure on either the systematic function of covariates or the distribution of the error term. A key advantage of our approach is its computational scalability in the number of covariates. For instance, even when assuming a normal error distribution as in probit models, commonly used sieves for approximating an unknown function of covariates can lead to a large-dimensional…

期望分位数周期图AI 解读

This paper introduces a novel periodogram-like function, called the expectile periodogram, for modeling spectral features of time series and detecting hidden periodicities. The expectile periodogram is constructed from trigonometric expectile regression, in which a specially designed check function is used to substitute the squared $l_2$ norm that leads to the ordinary periodogram. The expectile periodogram retains the key properties of the ordinary periodogram as a…

从分类视角利用自适应 LASSO 估计可解释的最优个体化治疗规则AI 解读

Real-world data (RWD) gains growing interests to provide a representative sample of the population for selecting the optimal treatment options. However, existing complex black box methods for estimating individualized treatment rules (ITR) from RWD have problems in interpretability and convergence. Providing an interpretable and sparse ITR can be used to overcome the limitation of existing methods. We developed an algorithm using Adaptive LASSO to predict optimal…

利用图卷积自编码器学习并检验干扰的暴露映射AI 解读

Interference or spillover effects arise when an individual's outcome (e.g., health) is influenced not only by their own treatment (e.g., vaccination) but also by the treatment of others, creating challenges for evaluating treatment effects. Exposure mappings provide a framework to study such interference by explicitly modeling how the treatment statuses of contacts within an individual's network affect their outcome. Most existing research relies on a priori exposure…

XGBoost 学习的是什么函数？AI 解读

This paper establishes a rigorous theoretical foundation for the function class implicitly learned by XGBoost, bridging the gap between its empirical success and our theoretical understanding. We introduce an infinite-dimensional function class $\mathcal{F}^{d, s}_{\infty-\text{ST}}$ that extends finite ensembles of bounded-depth regression trees, together with a complexity measure $V^{d, s}_{\infty-\text{XGB}}(\cdot)$ that generalizes the $L^1$ regularization penalty used…

随机深度学习：结构化时间数据不确定性建模的概率框架AI 解读

I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach, termed Stochastic Latent Differential Inference (SLDI), embeds an Itô SDE in the latent space of a variational autoencoder, allowing for flexible, continuous-time modeling of uncertainty while preserving a principled mathematical…

揭示实用性老年医学试验中的处理效应异质性AI 解读

Detecting heterogeneity in treatment response enriches the interpretation of gerontologic trials. In aging research, estimating the effect of the intervention on clinically meaningful outcomes faces analytical challenges when it is truncated by death. For example, in the Whole Systems Demonstrator trial, a large cluster-randomized study evaluating telecare among older adults, the overall effect of the intervention on quality of life was found to be null. However, this…

双重机器学习中病态正交得分的误差放大AI 解读

Double Machine Learning is often justified by nuisance-rate conditions, yet finite-sample reliability also depends on the conditioning of the orthogonal-score Jacobian. This conditioning is typically assumed rather than tracked. When residualized treatment variance is small, the Jacobian is ill-conditioned and small systematic nuisance errors can be amplified, so nominal confidence intervals may look precise yet systematically under-cover. Our main result is an exact…

基于强化学习的高效动态离散选择模型条件选择模拟估计AI 解读

Dynamic discrete choice (DDC) models have found widespread application in marketing. However, estimating these becomes challenging in "big data" settings with high-dimensional state-action spaces. To address this challenge, this paper develops a Reinforcement Learning (RL)-based two-step ("computationally light") Conditional Choice Simulation (CCS) estimation approach that combines the scalability of machine learning with the transparency, explainability, and…

普通病区患者安置优化：以工具变量因果森林降低死亡率AI 解读

Normal care units (NCU) placement affects health outcomes. NCUs in a hospital have different specialisations. There are patients that can potentially stay in multiple different NCUs. On a given day the NCUs are on different utilisation levels, which also affects health outcomes. Our approach uses instrumental variable causal forests, with emergency admission as an instrument, to estimate how the effect of NCU placement varies across patients and utilisation levels. The…

Although overparameterized models have achieved remarkable practical success, their theoretical properties, particularly their generalization behavior, remain incompletely understood. The well known double descents phenomenon suggests that the test error curve of neural networks decreases monotonically as model size grows and eventually converges to a non-zero constant. This work aims to explain the theoretical mechanism underlying this tail behavior and study the…

结合双重负向控制与图神经网络的双重差分：处理未观测网络混杂AI 解读

Estimating causal effects from observational network data faces dual challenges of network interference and unmeasured confounding. To address this, we propose a general Difference-in-Differences framework that integrates double negative controls (DNC) and graph neural networks (GNNs). Based on the modified parallel trends assumption and DNC, semiparametric identification of direct and indirect causal effects is established. We then propose doubly robust estimators.…

多弱工具变量下的非参数工具变量推断AI 解读

We study inference on linear functionals in the nonparametric instrumental variable (NPIV) problem with a discretely-valued instrument under a many-weak-instruments asymptotic regime, where the number of instrument values grows with the sample size. A key motivating example is estimating long-term causal effects in a new experiment with only short-term outcomes, using past experiments to instrument for the effect of short- on long-term outcomes. Here, the assignment to a…