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Detecting and Mitigating Group Bias in Heterogeneous Treatment Effects

异质性处理效应中的群体偏差检测与缓解

Heterogeneous treatment effects (HTEs) are increasingly estimated using machine learning models that produce highly personalized predictions of treatment effects. In practice, however, predicted treatment effects are rarely interpreted, reported, or audited at the individual level but, instead, are often aggregated to broader subgroups, such as demographic segments, risk strata, or markets. We show that such aggregation can induce systematic bias of the group-level causal…

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Model Selection in High-Dimensional Linear Regression using Boosting with Multiple Testing

结合提升与多重检验的高维线性回归模型选择

High-dimensional regression specification and analysis is a complex and active area of research in statistics, machine learning, and econometrics. This paper proposes a new approach, Boosting with Multiple Testing (BMT), which combines forward stepwise variable selection with the multiple testing framework of Chudik et al (2018). At each stage, the model is updated by adding only the most significant regressor conditional on those already included, while a family-wise…

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Testing Effect Homogeneity and Confounding in High-Dimensional Experimental and Observational Studies

高维实验与观察性研究中的效应同质性及混杂检验

We propose a framework for testing the homogeneity of conditional average treatment effects (CATEs) across multiple experimental and observational studies. Our approach leverages multiple randomized trials to assess whether treatment effects vary with unobserved heterogeneity that differs across trials: if CATEs are homogeneous, this indicates the absence of interactions between treatment and unobservables in the mean effect. Comparing CATEs between experimental and…

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Perturbed Double Machine Learning: Nonstandard Inference Beyond the Parametric Length

扰动双重机器学习:超越参数化长度的非标准推断

We study inference on a low-dimensional functional $β$ in the presence of infinite-dimensional nuisance parameters. Classical inferential methods are typically based on Wald intervals, whose large-sample validity rests on asymptotic negligibility of nuisance error; for example, influence-curve based estimators (Double/Debiased Machine Learning, DML) are asymptotically Gaussian when nuisance estimators converge faster than $n^{-1/4}$. Although such negligibility can hold even…

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Spatiotemporal double machine learning to estimate the impact of Cambodian land concessions on deforestation

时空双重机器学习:估计柬埔寨土地特许经营对森林砍伐的影响

Environmental policy evaluation frequently requires thoughtful consideration of space and time in causal inference. We use novel statistical methods to analyze the causal effect of land concessions on deforestation rates in Cambodia. Standard approaches, such as difference-in-differences regression, effectively address spatiotemporally-correlated treatments under some conditions, but they are limited in their ability to account for unobserved confounders affecting both…

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Information-Theoretic Causal Bounds under Unmeasured Confounding

未测混杂下的信息论因果界

We develop a data-driven information-theoretic framework for sharp partial identification of causal effects under unmeasured confounding. Existing approaches often rely on restrictive assumptions, such as bounded or discrete outcomes; require external inputs (for example, instrumental variables, proxies, or user-specified sensitivity parameters); necessitate full structural causal model specifications; or focus solely on population-level averages while neglecting…

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Concentration Inequalities for Suprema of Empirical Processes with Dependent Data via Generic Chaining with Applications to Statistical Learning

基于通用链式方法的依赖数据经验过程上确界集中不等式及统计学习应用

This paper develops a general concentration inequality for the suprema of empirical processes with dependent data. The concentration inequality is obtained by combining generic chaining with a coupling-based strategy. Our framework accommodates high-dimensional and heavy-tailed (sub-Weibull) data. We demonstrate the usefulness of our result by deriving non-asymptotic predictive performance guarantees for empirical risk minimization in regression problems with dependent data.…

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Optimal Unconstrained Self-Distillation in Ridge Regression: Strict Improvements, Precise Asymptotics, and One-Shot Tuning

岭回归中的最优无约束自蒸馏:严格改进、精确渐近与一次性调参

Self-distillation (SD) is the process of retraining a student on a mixture of ground-truth labels and the teacher's own predictions using the same architecture and training data. Although SD has been empirically shown to often improve generalization, its formal guarantees remain limited. We study SD for ridge regression in unconstrained setting in which the mixing weight $ξ$ may be outside the unit interval. Conditioned on the training data and without any distributional…

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genriesz: A Python Package for Automatic Debiased Machine Learning with Generalized Riesz Regression

genriesz:基于广义 Riesz 回归的自动去偏机器学习 Python 包

Efficient estimation of causal and structural parameters can be automated using the Riesz representation theorem and debiased machine learning (DML). We present genriesz, an open-source Python package that implements automatic DML and generalized Riesz regression, a unified framework for estimating Riesz representers by minimizing empirical Bregman divergences. This framework includes covariate balancing, nearest-neighbor matching, calibrated estimation, and density ratio…

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The super learner for time-to-event outcomes: A tutorial

事件发生时间结局的超级学习器:实践教程

Estimating risks or survival probabilities conditional on individual characteristics based on censored time-to-event data is a commonly faced task. This may be for the purpose of developing a prediction model or may be part of a wider estimation procedure, such as in causal inference. A challenge is that it is impossible to know at the outset which of a set of candidate models will provide the best risk estimates. The super learner is a powerful approach for finding the best…

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Estimating Zero-inflated Negative Binomial GAMLSS via a Balanced Gradient Boosting Approach with an Application to Antenatal Care Data from Nigeria

基于平衡梯度提升的零膨胀负二项GAMLSS估计及其在尼日利亚产前保健数据中的应用

Statistical boosting algorithms are renowned for their intrinsic variable selection and enhanced predictive performance compared to classical statistical methods, making them especially useful for complex models such as generalized additive models for location scale and shape (GAMLSS). Boosting this model class can suffer from imbalanced updates across the distribution parameters as well as long computation times. Shrunk optimal step lengths have been shown to address these…

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A Unifying Framework for Robust and Efficient Inference with Unstructured Data

非结构化数据稳健与有效推断的统一框架

To analyze unstructured data (text, images, audio, video), economists typically first extract low-dimensional structured features with a neural network. Neural networks do not make generically unbiased predictions, and biases will propagate to estimators that use their predictions. While structured variables extracted from unstructured data have traditionally been treated as proxies - implicitly accepting arbitrary measurement error - this poses various challenges in an era…

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Graph Machine Learning based Doubly Robust Estimator for Network Causal Effects

基于图机器学习的网络因果效应双重稳健估计

We address the challenge of inferring causal effects in social network data. This results in challenges due to interference -- where a unit's outcome is affected by neighbors' treatments -- and network-induced confounding factors. While there is extensive literature focusing on estimating causal effects in social network setups, a majority of them make prior assumptions about the form of network-induced confounding mechanisms. Such strong assumptions are rarely likely to…

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Proximal Causal Inference for Conditional Separable Effects

条件可分离效应的近端因果推断

Scientists regularly pose questions about treatment effects on outcomes conditional on a post-treatment event. However, causal inference in such settings requires care, even in perfectly executed randomized experiments. Recently, the conditional separable effect (CSE) was proposed as an interventionist estimand that corresponds to scientifically meaningful questions in these settings. However, existing results for the CSE require no unmeasured confounding between the outcome…

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Fixed-Horizon Self-Normalized Inference for Adaptive Experiments via Martingale AIPW/DML with Logged Propensities

记录分配概率的自适应实验:固定期限自归一化推断

Adaptive randomized experiments update treatment probabilities as data accrue, but still require an end-of-study interval for the average treatment effect (ATE) at a prespecified horizon. Under adaptive assignment, propensities can keep changing, so the predictable quadratic variation of AIPW/DML score increments may remain random. When no deterministic variance limit exists, Wald statistics normalized by a single long-run variance target can be conditionally miscalibrated…

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Nonparametric Identification and Inference for Counterfactual Distributions with Confounding

存在混杂时反事实分布的非参数识别与推断

We propose nonparametric identification and semiparametric estimation of joint potential outcome distributions in the presence of confounding. First, in settings with observed confounding, we derive tighter, covariate-informed bounds on the joint distribution by leveraging conditional copulas. To overcome the non-differentiability of bounding min/max operators, we establish the asymptotic properties for both a direct estimator with polynomial margin condition and a smooth…

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Efficient and Debiased Learning of Average Hazard Under Non-Proportional Hazards

非比例风险下平均风险率的高效去偏学习

The hazard ratio from the Cox proportional hazards model is a ubiquitous summary of treatment effect. However, when hazards are non-proportional, the hazard ratio can lose a stable causal interpretation and become study-dependent because it effectively averages time-varying effects with weights determined by follow-up and censoring. We consider the average hazard (AH) as an alternative causal estimand: a population-level person-time event rate that remains well-defined and…

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Quadruply robust methods for causal mediation analysis

因果中介分析的四重稳健方法

Estimating natural effects is a core task in causal mediation analysis. Existing triply robust (TR) frameworks (Tchetgen Tchetgen & Shpitser 2012) and their extensions have been developed to estimate the natural effects. In this work, we introduce a new quadruply robust (QR) framework that enlarges the model class for unbiased identification. We study two modeling strategies. The first is a nonparametric modeling approach, under which we propose a general QR estimator that…

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Towards Representation Learning for Weighting Problems in Design-Based Causal Inference

面向设计型因果加权问题的表征学习

Reweighting a distribution to minimize a distance to a target distribution is a powerful and flexible strategy for estimating a wide range of causal effects, but can be challenging in practice because optimal weights typically depend on knowledge of the underlying data generating process. In this paper, we focus on design-based weights, which do not incorporate outcome information; prominent examples include prospective cohort studies, survey weighting, and the weighting…

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Modern Causal Inference Approaches to Improve Power for Subgroup Analysis in Randomized Controlled Trials

利用现代因果推断提高随机对照试验亚组分析的检验力

Randomized controlled trials (RCTs) often include subgroup analyses to assess whether treatment effects vary across pre-specified patient populations. However, these analyses frequently suffer from small sample sizes which limit the power to detect heterogeneous effects. Power can be improved by leveraging predictors of the outcome -- i.e., through covariate adjustment -- as well as by borrowing external data from similar RCTs or observational studies. The benefits of…

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A Doubly Robust Machine Learning Approach for Disentangling Treatment Effect Heterogeneity with Functional Outcomes

分解函数型结局处理效应异质性的双重稳健机器学习方法

Causal inference is paramount for understanding the effects of interventions, yet extracting personalized insights from increasingly complex data remains a significant challenge for modern machine learning. This is the case, in particular, when considering functional outcomes observed over a continuous domain (e.g., time, or space). Estimation of heterogeneous treatment effects, known as CATE, has emerged as a crucial tool for personalized decision-making, but existing…

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Optimizing precision in stepped-wedge designs via machine learning and quadratic inference functions

通过机器学习与二次推断函数优化阶梯楔形设计的估计精度

Stepped-wedge designs are increasingly used in randomized experiments to accommodate logistical and ethical constraints by staggering treatment roll-out over time. Despite their popularity, existing analytical methods largely rely on parametric models with linear covariate adjustment and prespecified correlation structures, which may limit achievable precision in practice. We propose a new class of estimators for the causal average treatment effect in stepped-wedge designs…

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Generalized Prediction-Powered Inference, with Application to Binary Classifier Evaluation

广义预测驱动推断及其在二分类器评估中的应用

In the partially-observed outcome setting, a recent set of proposals known as "prediction-powered inference" (PPI) involve (i) applying a pre-trained machine learning model to predict the response, and then (ii) using these predictions to obtain an estimator of the parameter of interest with asymptotic variance no greater than that which would be obtained using only the labeled observations. While existing PPI proposals consider estimators arising from M-estimation, in this…

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Fixed Effects as Generated Regressors

作为生成回归变量的固定效应

Many economic models feature moment conditions that involve latent variables. When the latent variables are individual fixed effects in an auxiliary panel data regression, we construct orthogonal moments that eliminate first-order bias induced by estimating the fixed effects. Machine Learning methods and Empirical Bayes methods can be used to improve the estimate of the nuisance parameters in the orthogonal moments. We establish a central limit theorem based on the…

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