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工具变量:IV、2SLS 与内生性识别。
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Machine learning the first stage in 2SLS: Practical guidance from bias decomposition and simulation

在 2SLS 第一阶段使用机器学习:来自偏差分解与模拟的实践指导

Machine learning (ML) primarily evolved to solve "prediction problems." The first stage of two-stage least squares (2SLS) is a prediction problem, suggesting potential gains from ML first-stage assistance. However, little guidance exists on when ML helps 2SLS$\unicode{x2014}$or when it hurts. We investigate the implications of inserting ML into 2SLS, decomposing the bias into three informative components. Mechanically, ML-in-2SLS procedures face issues common to prediction…

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Optimization-based Sensitivity Analysis for Unmeasured Confounding using Partial Correlations

利用偏相关的未观测混杂优化敏感性分析

Causal inference necessarily relies upon untestable assumptions; hence, it is crucial to assess the robustness of obtained results to violations of identification assumptions. However, such sensitivity analysis is only occasionally undertaken in practice, as many existing methods require analytically tractable solutions and their results are often difficult to interpret. We take a more flexible approach to sensitivity analysis and view it as a constrained stochastic…

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Sequential Treatment Effect Estimation with Unmeasured Confounders

存在未测量混杂时的序贯处理效应估计

This paper studies the cumulative causal effects of sequential treatments in the presence of unmeasured confounders. It is a critical issue in sequential decision-making scenarios where treatment decisions and outcomes dynamically evolve over time. Advanced causal methods apply transformer as a backbone to model such time sequences, which shows superiority in capturing long time dependence and periodic patterns via attention mechanism. However, even they control the observed…

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Transformers Handle Endogeneity in In-Context Linear Regression

Transformer 在上下文线性回归中处理内生性

We explore the capability of transformers to address endogeneity in in-context linear regression. Our main finding is that transformers inherently possess a mechanism to handle endogeneity effectively using instrumental variables (IV). First, we demonstrate that the transformer architecture can emulate a gradient-based bi-level optimization procedure that converges to the widely used two-stage least squares $(\textsf{2SLS})$ solution at an exponential rate. Next, we propose…

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Generalized M-Estimation in Censored Regression Model under Endogeneity

内生性下删失回归模型的广义 M 估计

We propose and study M-estimation to estimate the parameters in the censored regression model in the presence of endogeneity, i.e., the Tobit model. In the course of this study, we follow two-stage procedures: the first stage consists of applying control function procedures to address the issue of endogeneity using instrumental variables, and the second stage applies the M-estimation technique to estimate the unknown parameters involved in the model. The large sample…

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Policy Relevant Treatment Effects with Multidimensional Unobserved Heterogeneity

多维未观测异质性下的政策相关处理效应

This paper provides a unified framework for bounding policy relevant treatment effects using instrumental variables. In this framework, the treatment selection may depend on multidimensional unobserved heterogeneity. We derive bilinear constraints on the target parameter by extracting information from identifiable estimands. We apply a convex relaxation method to these bilinear constraints and provide conservative yet computationally simple bounds. Our convex-relaxation…

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Inference of high-dimensional weak instrumental variable regression models without ridge-regularization

无需岭正则化的高维弱工具变量回归推断

Inference of instrumental variable regression models with many weak instruments attracts many attentions recently. To extend the classical Anderson-Rubin test to high-dimensional setting, many procedures adopt ridge-regularization. However, we show that it is not necessary to consider ridge-regularization. Actually we propose a new quadratic-type test statistic which does not involve tuning parameters. Our quadratic-type test exhibits high power against dense alternatives.…

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Debiased Estimating Equation Method for Robust and Efficient Mendelian Randomization Using a Large Number of Correlated Weak and Invalid Instruments

使用大量相关弱工具和无效工具的稳健有效孟德尔随机化:去偏估计方程法

Mendelian randomization (MR) is a widely used tool for causal inference in the presence of unmeasured confounders, which uses single nucleotide polymorphisms (SNPs) as instrumental variables to estimate causal effects. However, SNPs often have weak effects on complex traits, leading to bias in existing MR analysis when weak instruments are included. In addition, existing MR methods often restrict analysis to independent SNPs via linkage disequilibrium clumping and result in…

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Negative Control Falsification Tests for Instrumental Variable Designs

工具变量设计的负对照证伪检验

The validity of instrumental variable (IV) designs is typically tested using two types of falsification tests. We characterize these tests as conditional independence tests between negative control variables -- proxies for unobserved variables posing a threat to the identification -- and the IV or the outcome. We describe the conditions that variables must satisfy in order to serve as negative controls. We show that these falsification tests examine not only independence and…

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Causal Q-Aggregation for CATE Model Selection

用于条件平均处理效应模型选择的因果 Q 聚合

Accurate estimation of conditional average treatment effects (CATE) is at the core of personalized decision making. While there is a plethora of models for CATE estimation, model selection is a nontrivial task, due to the fundamental problem of causal inference. Recent empirical work provides evidence in favor of proxy loss metrics with double robust properties and in favor of model ensembling. However, theoretical understanding is lacking. Direct application of prior…

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Identification and estimation of causal peer effects using instrumental variables

利用工具变量识别和估计因果同伴效应

In social science researches, causal inference regarding peer effects often faces significant challenges due to homophily bias and contextual confounding. For example, unmeasured health conditions (e.g., influenza) and psychological states (e.g., happiness, loneliness) can spread among closely connected individuals, such as couples or siblings. To address these issues, we define four effect estimands for dyadic data to characterize direct effects and spillover effects. We…

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Inference with Many Weak Instruments and Heterogeneity

大量弱工具变量与处理效应异质性下的推断

This paper considers inference in a linear instrumental variable regression model with many potentially weak instruments, in the presence of heterogeneous treatment effects. I first show that existing test procedures, including those that are robust to either weak instruments or heterogeneous treatment effects, can be arbitrarily oversized. I propose a novel and valid test based on a score statistic and a ``leave-three-out" variance estimator. In the presence of…

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Dynamic Discrete-Continuous Choice Models: Identification and Conditional Choice Probability Estimation

动态离散与连续选择模型:识别与条件选择概率估计

This paper develops a general framework for dynamic models in which individuals simultaneously make both discrete and continuous choices. The framework incorporates a wide range of unobserved heterogeneity. I show that such models are nonparametrically identified. Based on constructive identification arguments, I build a novel two-step estimation method in the lineage of Hotz and Miller (1993) and Arcidiacono and Miller (2011) but extended to simultaneous discrete-continuous…

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Estimation and inference in error-in-operator model

算子含误差模型中的估计与推断

Many statistical problems can be reduced to a linear inverse problem in which only a noisy version of the operator is available. Particular examples include random design regression, deconvolution problem, instrumental variable regression, functional data analysis, error-in-variable regression, drift estimation in stochastic diffusion, and many others. The pragmatic plug-in approach can be well justified in the classical asymptotic setup with a growing sample size. However,…

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Addressing Positivity Violations in Extending Inference to a Target Population

将推断推广至目标总体时应对正值性违背

Enhancing the external validity of trial results is essential for their applicability to real-world populations. However, violations of the positivity assumption can limit both the generalizability and transportability of findings. To address positivity violations in estimating the average treatment effect for a target population, we propose a framework that integrates characterizing the underrepresented group and performing sensitivity analysis for inference in the original…

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Semiparametric Causal Discovery and Inference with Invalid Instruments

容许无效工具变量的半参数因果发现与推断

Learning causal relationships among a set of variables, as encoded by a directed acyclic graph, from observational data is complicated by the presence of unobserved confounders. Instrumental variables (IVs) are a popular remedy for this issue, but most existing methods either assume the validity of all IVs or postulate a specific form of relationship, such as a linear model, between the primary variables and the IVs. To overcome these limitations, we introduce a partially…

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Estimating Demand with Recentered Instruments

利用再中心化工具变量估计需求

We develop a new approach to estimating flexible demand models with exogenous supply-side shocks. Our approach avoids conventional assumptions of exogenous product characteristics, putting no restrictions on product entry, despite using instrumental variables that incorporate characteristic variation. The proposed instruments are model-predicted responses of endogenous variables to the exogenous shocks, recentered to avoid bias from endogenous characteristics. We illustrate…

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Enhancing Causal Effect Estimation with Diffusion-Generated Data

利用扩散模型生成数据增强因果效应估计

Estimating causal effects from observational data is inherently challenging due to the lack of observable counterfactual outcomes and even the presence of unmeasured confounding. Traditional methods often rely on restrictive, untestable assumptions or necessitate valid instrumental variables, significantly limiting their applicability and robustness. In this paper, we introduce Augmented Causal Effect Estimation (ACEE), an innovative approach that utilizes synthetic data…

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Estimation of the complier causal hazard ratio under dependent censoring

依赖删失下服从者因果风险比的估计

In this work, we are interested in studying the causal effect of an endogenous binary treatment on a dependently censored duration outcome. By dependent censoring, it is meant that the duration time ($T$) and right censoring time ($C$) are not statistically independent of each other, even after conditioning on the measured covariates. The endogeneity issue is handled by making use of a binary instrumental variable for the treatment. To deal with the dependent censoring…

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Adding covariates to bounds: What is the question?

给识别界加入协变量:究竟要回答什么问题?

Symbolic nonparametric bounds for partial identification of causal effects now have a long history in the causal literature. Sharp bounds, bounds that use all available information to make the range of values as narrow as possible, are often the goal. For this reason, many publications have focused on deriving sharp bounds, but the concept of sharp bounds is nuanced and can be misleading. In settings with ancillary covariates, the situation becomes more complex. We provide…

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Robust Identification in Randomized Experiments with Noncompliance

存在不依从的随机实验中的稳健识别

Instrument variable (IV) methods are widely used in empirical research to identify causal effects of a policy. In the local average treatment effect (LATE) framework, the IV estimand identifies the LATE under three main assumptions: random assignment, exclusion restriction, and monotonicity. However, these assumptions are often questionable in many applications, leading some researchers to doubt the causal interpretation of the IV estimand. This paper considers a robust…

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Linear programming approach to partially identified econometric models

部分识别计量模型的线性规划方法

Sharp bounds on partially identified parameters are often given by the values of linear programs (LPs). This paper introduces a novel estimator of the LP value. Unlike existing procedures, our estimator is root-n-consistent, pointwise in the probability measure, whenever the population LP is feasible and finite. Our estimator is valid under point-identification, over-identifying constraints, and solution multiplicity. Turning to uniformity properties, we prove that the LP…

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A Doubly Robust Instrumental Variable Approach for Estimating Average Treatment Effects in Time-to-Event Data with Unmeasured Confounding: Application to Real-World Data on ICU Patients with Septic Shock

未测混杂下生存结局平均处理效应的双重稳健工具变量方法

Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE) in time-to-event data. In real-world data, IV methods are widely used for estimating causal treatment effects in the presence of unmeasured confounding, but existing approaches for time-to-event outcomes are often constrained by strong…

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BudgetIV: Optimal Partial Identification of Causal Effects with Mostly Invalid Instruments

BudgetIV:多数工具变量无效时因果效应的最优部分识别

Instrumental variables (IVs) are widely used to estimate causal effects in the presence of unobserved confounding between exposure and outcome. An IV must affect the outcome exclusively through the exposure and be unconfounded with the outcome. We present a framework for relaxing either or both of these strong assumptions with tuneable and interpretable budget constraints. Our algorithm returns a feasible set of causal effects that can be identified exactly given relevant…

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