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孟德尔随机化因果推断方法：估计对象、识别与推断AI 解读

Mendelian randomization (MR) has become an essential tool for causal inference in biomedical and public health research. By using genetic variants as instrumental variables, MR helps address unmeasured confounding and reverse causation, offering a quasi-experimental framework to evaluate causal effects of modifiable exposures on health outcomes. Despite its promise, MR faces substantial methodological challenges, including invalid instruments, weak instrument bias, and…

基于距离协方差的估计量AI 解读

This paper proposes an estimator that relaxes the conventional relevance condition in instrumental variable (IV) analyses. The method allows endogenous covariates to be weakly correlated, uncorrelated, or even mean-independent -- though not independent -- of the instruments, enabling the use of the maximal set of relevant instruments in a given application. Identification is attainable without exclusion restrictions and without finite-moment assumptions on the disturbance…

无需指定网络结构的同伴效应检验AI 解读

This paper proposes an Anderson-Rubin (AR) test for the presence of peer effects in panel data without the need to specify the network structure. The unrestricted model of our test is a linear panel data model of social interactions with dyad-specific peer effect coefficients for all potential peers. The proposed AR test evaluates if these peer effect coefficients are all zero. As the number of peer effect coefficients increases with the sample size, so does the number of…

存在不依从时的高效自适应实验AI 解读

We study the problem of estimating the average treatment effect (ATE) in adaptive experiments where treatment can only be encouraged -- rather than directly assigned -- via a binary instrumental variable. Building on semiparametric efficiency theory, we derive the efficiency bound for ATE estimation under arbitrary, history-dependent instrument-assignment policies, and show it is minimized by a variance-aware allocation rule that balances outcome noise and compliance…

基于分层的非线性效应工具变量分析框架AI 解读

Nonlinear causal effects are prevalent in many research scenarios involving continuous exposures, and instrumental variables (IVs) can be employed to investigate such effects, particularly in the presence of unmeasured confounders. However, common IV methods for nonlinear effect analysis, such as IV regression or the control-function method, have inherent limitations, leading to either low statistical power or potentially misleading conclusions. In this work, we propose an…

超越平均效应：不完全依从下的分布因果推断AI 解读

We study the estimation of distributional treatment effects in randomized experiments with imperfect compliance. When participants do not adhere to their assigned treatments, we leverage treatment assignment as an instrumental variable to identify the local distributional treatment effect-the difference in outcome distributions between treatment and control groups for the subpopulation of compliers. We propose a regression-adjusted estimator based on a distribution…

分位数处理效应、秩相似性与工具变量变异AI 解读

This paper develops a nonparametric framework to identify and estimate distributional treatment effects under nonseparable endogeneity. We begin by revisiting the widely adopted \emph{rank similarity} (RS) assumption and characterizing it by the relationship it imposes between observed and counterfactual potential outcome distributions. The characterization highlights the restrictiveness of RS, motivating a weaker identifying condition. Under this alternative, we construct…

空间标量对函数分位数回归模型AI 解读

This paper introduces a novel spatial scalar-on-function quantile regression model that extends classical scalar-on-function models to account for spatial dependence and heterogeneous conditional distributions. The proposed model incorporates spatial autocorrelation through a spatially lagged response and characterizes the entire conditional distribution of a scalar outcome given a functional predictor. To address the endogeneity induced by the spatial lag term, we develop…

高维工具变量与控制变量下的处理效应推断AI 解读

Obtaining valid treatment effect inference remains a challenging problem when dealing with numerous instruments and non-sparse control variables. In this paper, we propose a novel ridge regularization-based instrumental variables method for estimation and inference in the presence of both high-dimensional instrumental variables and high-dimensional control variables. These methods are applicable both with and without sparsity assumptions. To remove the estimation bias, we…

聚类工具变量模型中多工具与弱工具下的推断AI 解读

Data clustering reduces the effective sample size from the number of observations towards the number of clusters. For instrumental variable models this reduced effective sample size makes the instruments more likely to be weak, in the sense that they contain little information about the endogenous regressor, and many, in the sense that their number is large compared to the sample size. Consequently, weak and many instrument problems for estimators and tests in instrumental…

Bootstrap 诊断检验AI 解读

Violation of the assumptions underlying classical (Gaussian) limit theory often yields unreliable statistical inference. This paper shows that the bootstrap can detect such violations by delivering simple and powerful diagnostic tests that (a) induce no pre-testing bias, (b) use the same critical values across applications, and (c) are consistent against deviations from asymptotic normality. The tests compare the conditional distribution of a bootstrap statistic with the…

二元结果工具变量模型的崩溃分析AI 解读

This paper studies the partial identification of treatment effects in Instrumental Variables (IV) settings with binary outcomes under violations of independence. I derive the identified sets for the treatment parameters of interest in the setting, as well as breakdown values for conclusions regarding the true treatment effects. I derive $\sqrt{N}$-consistent nonparametric estimators for the bounds of treatment effects and for breakdown values. These results can be used to…

非随机缺失数据的乘法工具变量模型AI 解读

Instrumental variable (IV) methods offer a valuable approach to account for outcome data missing not-at-random. A valid missing data instrument is a measured factor which (i) predicts the nonresponse process and (ii) is independent of the outcome in the underlying population. For point identification, all existing IV methods for missing data including the celebrated Heckman selection model, a priori restrict the extent of selection bias on the outcome scale, therefore…

群组标签偏移下的迁移学习：半参数指数倾斜方法AI 解读

We propose a new framework for binary classification in transfer learning settings where both covariate and label distributions may shift between source and target domains. Unlike traditional covariate shift or label shift assumptions, we introduce a group-label shift assumption that accommodates subpopulation imbalance and mitigates spurious correlations, thereby improving robustness to real-world distributional changes. To model the joint distribution difference, we adopt…

弱工具变量与异方差下的过度识别检验AI 解读

Exogeneity is key for IV estimators, which can assessed via overidentification (OID) tests. We discuss the Kleibergen-Paap (KP) rank test as a heteroskedasticity-robust OID test and compare to the typical J-test. We derive the heteroskedastic weak-instrument limiting distributions for J and KP as special cases of the robust score test estimated via 2SLS and LIML respectively. Monte Carlo simulations show that KP usually performs better than J, which is prone to severe size…

不必完全排除：使用半工具变量开展因果推断AI 解读

This paper proposes semi-instrumental variables (semi-IVs) as an alternative to instrumental variables (IVs) to identify the causal effect of a binary (or discrete) endogenous treatment. A semi-IV is a less restrictive form of instrument: it affects the selection into treatment but is excluded only from one, not necessarily both, potential outcomes. Having two continuously distributed semi-IVs, one excluded from the potential outcome under treatment and the other from the…

协变量平衡与平均处理效应加权、双重稳健估计量的等价性AI 解读

How should researchers adjust for covariates? We show that if the propensity score is estimated using a specific covariate balancing approach, inverse probability weighting (IPW), augmented inverse probability weighting (AIPW), and inverse probability weighted regression adjustment (IPWRA) estimators are numerically equivalent for the average treatment effect (ATE), and likewise for the average treatment effect on the treated (ATT). The resulting weights are inherently…

稳定隐性混杂与二元结果的准工具变量方法AI 解读

Instrumental variable (IV) methods are central to causal inference from observational data, particularly when a randomized experiment is not feasible. However, of the three conventional core IV identification conditions, only one, IV relevance, is empirically verifiable; often one or both of the other conditions, exclusion restriction and IV independence from unmeasured confounders, are unmet in real-world applications. These challenges are compounded when the outcome is…

回归模型中的对数与零值问题AI 解读

The log transformation is widely used in linear regression, mainly because coefficients are interpretable as proportional effects. Yet this practice has fundamental limitations, most notably that the log is undefined at zero, creating an identification problem. We propose a new estimator, iterated OLS (iOLS), which targets the normalized average treatment effect, preserving the percentage-change interpretation while addressing these limitations. Our procedure is the…

利用工具变量处理不可忽略缺失数据的统计方法综述AI 解读

Nonignorable missing data, where the probability of missingness depends on unobserved values, presents a significant challenge in statistical analysis. Traditional methods often rely on strong parametric assumptions that are difficult to verify and may lead to biased estimates if misspecified. Recent advances have introduced the concept of a nonresponse instrument or shadow variable as a powerful tool to enhance model identifiability without requiring full parametric…

存在干扰时利用工具变量估计政策相关因果效应AI 解读

Many policy evaluations using instrumental variable (IV) methods include individuals who interact with each other, potentially violating the standard IV assumptions. This paper defines and partially identifies direct and spillover effects with a clear policy-relevant interpretation under relatively mild assumptions on interference. Our framework accommodates both spillovers from the instrument to treatment and from treatment to outcomes and allows for multiple peers. By…

利用函数型工具变量校正标量对函数回归偏差的最小二乘方法AI 解读

Instrumental variables are widely used to adjust for measurement error bias when assessing associations of health outcomes with ME prone independent variables. IV approaches addressing ME in longitudinal models are well established, but few methods exist for functional regression. We develop two methods to adjust for ME bias in scalar on function linear models. We regress a scalar outcome on an ME prone functional variable using a functional IV for model identification and…

右删失数据下半参数加速失效时间模型的两阶段最小二乘工具变量估计AI 解读

Instrumental variable (IV) analysis is widely used in fields such as economics and epidemiology to address unobserved confounding and measurement error when estimating the causal effects of intermediate covariates on outcomes. However, extending the commonly used two-stage least squares (TSLS) approach to survival settings is nontrivial due to censoring. This paper introduces a novel extension of TSLS to the semiparametric accelerated failure time (AFT) model with…

网络连边误分类下的社会网络模型估计AI 解读

We propose an adjusted 2SLS estimator for social network models when reported binary network links are misclassified (some zeros reported as ones and vice versa) due, e.g., to survey respondents' recall errors, or lapses in data input. We show misclassification adds new sources of correlation between the regressors and errors, which makes all covariates endogenous and invalidates conventional estimators. We resolve these issues by constructing a novel estimator of…