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Sequentially-Rerandomized Switchback Experiments

序贯重随机化切换实验

Large-scale online platforms and marketplace systems often evaluate new policies through experiments that randomize treatment across operational units (e.g., geographies, regions, or clusters) over many time periods. In these settings, standard A/B testing can be inefficient or unreliable due to a limited number of units, substantial cross-unit heterogeneity, non-stationarity, and potential carryover across periods. We propose Sequentially-Rerandomized Switchback Experiments…

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Covariate-Balanced Weighted Stacked Difference-in-Differences

协变量平衡的加权堆叠双重差分

This paper proposes Covariate-Balanced Weighted Stacked Difference-in-Differences (CBWSDID), a design-based extension of weighted stacked DID for settings in which untreated trends may be conditionally rather than unconditionally parallel. The estimator separates within-subexperiment design adjustment from across-subexperiment aggregation: matching or weighting improves treated-control comparability within each stacked subexperiment, while the corrective stacked weights of…

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Generalized Machine Learning for Fast Calibration of Agent-Based Epidemic Models

用于智能体流行病模型快速校准的机器学习方法

Agent-based models (ABMs) are widely used to study infectious disease dynamics, but their calibration is often computationally intensive, limiting their applicability in time-sensitive public health settings. We propose DeepIMC (Deep Inverse Mapping Calibration), a machine learning-based calibration framework that directly learns the inverse mapping from epidemic time series to epidemiological parameters. DeepIMC trains a bidirectional Long Short-Term Memory (BiLSTM) neural…

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Two-stage Least Squares with Clustered Data under the Local Average Treatment Effect Framework

局部平均处理效应框架下聚类数据的两阶段最小二乘

To estimate the causal effect of an endogenous treatment using clustered data, the canonical two-stage least squares (2sls) estimates a linear regression of the outcome on treatment status using an instrumental variable (IV) and conducts inference with cluster-robust standard errors. When both the treatment and the IV vary within clusters, an alternative two-stage least squares with fixed effects (2sfe) additionally includes cluster indicators in the regression, thereby…

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Measuring What Cannot Be Surveyed: LLMs as Instruments for Latent Cognitive Variables in Labor Economics

衡量无法调查的变量:大语言模型作为劳动经济学的潜在认知测量工具

This paper establishes the theoretical and practical foundations for using Large Language Models (LLMs) as measurement instruments for latent economic variables -- specifically variables that describe the cognitive content of occupational tasks at a level of granularity not achievable with existing survey instruments. I formalize four conditions under which LLM-generated scores constitute valid instruments: semantic exogeneity, construct relevance, monotonicity, and model…

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Causal K-Means Clustering

因果 K 均值聚类

Causal effects are often characterized with population summaries. These might provide an incomplete picture when there are heterogeneous treatment effects across subgroups. Since the subgroup structure is typically unknown, it is more challenging to identify and evaluate subgroup effects than population effects. We propose a new solution to this problem: \emph{Causal k-Means Clustering}, which leverages the k-means clustering algorithm to uncover the unknown subgroup…

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A new wavelet-based variational family with copula dependence structures

基于小波与Copula依赖结构的变分推断族

Variational inference (VI) has become a widely used approach for scalable Bayesian inference, but its performance strongly depends on the flexibility of the chosen variational family. In this work, we propose a novel variational family that combines wavelet-based representations for marginal posterior densities with copula functions to model dependence structures. The marginal distributions are constructed using coefficients from the discrete wavelet transform, providing a…

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When Can We Trust Cluster-Robust Inference?

何时可以信赖聚类稳健推断?

It is common when using cross-section or panel data to assign each observation to a cluster and allow for arbitrary patterns of heteroskedasticity and correlation within clusters. For regression models, there are many ways to make cluster-robust inferences. A number of different variance matrix estimators can be used. Hypothesis tests and confidence intervals can then be based on several alternative analytic or bootstrap distributions. Some methods typically perform much…

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Causal-ICM: A Data Fusion Framework For Heterogeneous Treatment Effect Estimation With Multi-Task Gaussian Processes

Causal-ICM:用多任务高斯过程融合数据估计异质处理效应

Bridging the gap between internal and external validity is crucial for heterogeneous treatment effect estimation. Randomised controlled trials (RCTs), favoured for their internal validity due to randomisation, often encounter challenges in generalising findings due to strict eligibility criteria. Observational studies, on the other hand, may provide stronger external validity through larger and more representative samples but can suffer from compromised internal validity due…

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Nonparametric estimation of the total treatment effect with multiple outcomes in the presence of terminal events

终末事件存在时多结局总处理效应的非参数估计

As standards of care advance, patients are living longer and once-fatal diseases are becoming manageable. Clinical trials increasingly focus on reducing disease burden, which can be quantified by the timing and occurrence of multiple non-fatal clinical events. Most existing methods for the analysis of multiple event-time data require stringent modeling assumptions that can be difficult to verify empirically, leading to treatment efficacy estimates that forego…

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Identifying and Estimating Causal Direct Effects Under Unmeasured Confounding

未测量混杂下因果直接效应的识别与估计

Causal mediation analysis provides techniques for defining and estimating effects that may be endowed with mechanistic interpretations. With many scientific investigations seeking to address mechanistic questions, causal direct and indirect effects have garnered much attention. The natural direct and indirect effects, the most widely used among such causal mediation estimands, are limited in their practical utility due to stringent identification requirements. Accordingly,…

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Sharp Debiasing for Smooth Functional Estimation in Banach Spaces

Banach 空间中光滑泛函估计的锐利去偏

This paper studies the estimation of smooth functionals $f(θ)$ of a mean parameter $θ= \mathbb{E}_P[W]$ for a distribution $P$ on a general Banach space. We propose a cross-fitted estimator based on a single sample splitting and establish non-asymptotic moment bounds and Berry--Esséen bounds for both $m$-smooth and infinitely smooth functionals under the finite moment assumptions. Our framework is applied to precision matrix estimation and the inference of projection…

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Adaptive Nonparametric Perturbations of Parametric Models with Generalized Bayes

通过广义贝叶斯对参数模型进行自适应非参数扰动

Parametric Bayesian modeling offers a powerful and flexible toolbox for machine learning. Yet the model, however detailed, may still be wrong, and this can make inferences untrustworthy. In this paper we introduce a new class of semiparametric corrections for parametric Bayesian models, when the target of inference is a functional of the true data distribution. Our starting point is a fully Bayesian modeling approach, which explicitly accounts for the possibility that the…

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Regularizing Attention Scores with Bootstrapping

用自助法正则化注意力分数

Vision transformers (ViT) rely on attention mechanism to weigh input features, and therefore attention scores have naturally been considered as explanations for its decision-making process. However, attention scores are almost always non-zero, resulting in noisy and diffused attention maps and limiting interpretability. Can we quantify uncertainty measures of attention scores and obtain regularized attention scores? To this end, we consider attention scores of ViT in a…

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The Digital Twin Counterfactual Framework: A Validation Architecture for Simulated Potential Outcomes

数字孪生反事实框架:模拟潜在结果的验证架构

The fundamental problem of causal inference - that the counterfactual outcome for any individual is never observed - has shaped the entire methodology of the field. Every existing approach substitutes assumptions for missing data: ignorability, parallel trends, exclusion restrictions. None produces the counterfactual itself. This paper proposes the Digital Twin Counterfactual Framework (DTCF): rather than estimating the counterfactual statistically, we simulate it using a…

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Predicted Incrementality by Experimentation (PIE) for Ad Measurement

基于实验预测广告增量效果:PIE 广告衡量方法

Randomized controlled trials (RCTs) provide the most credible estimates of advertising incrementality but are difficult to scale. We propose Predicted Incrementality by Experimentation (PIE), which reframes ad measurement as a campaign-level prediction problem. PIE uses a sample of RCTs to learn a mapping from campaign features to causal effects, then applies it to campaigns not run as RCTs. Because the RCTs identify the causal effects, PIE can incorporate post-determined…

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Estimating causal effects of continuous-time dynamic treatments with unmeasured confounders

存在未测量混杂时连续时间动态处理的因果效应估计

Modern medical research demands specialized causal inference methods evaluating complex continuous-time dynamic treatment regimens using observational data. For instance, obtaining the causal effects of intravenous administration, a continuous process involving dynamic adjustments of the treatment dose, can guide clinicians on drug use. However, the existing causal inference frameworks in longitudinal studies typically assume that time advances in discrete time steps.…

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Dynamic linear regression models for forecasting time series with semi long memory errors

具有半长记忆误差的动态线性回归预测模型

Dynamic linear regression models forecast the values of a time series based on a linear combination of a set of exogenous time series while incorporating a time series process for the error term. This error process is often assumed to follow a stationary autoregressive integrated moving average (ARIMA) model, or its seasonal variants, which are unable to capture a long-range dependence structure (long memory) of the error process. We propose a novel dynamic linear regression…

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Regularizing Extrapolation in Causal Inference

因果推断中的外推正则化

Many common estimators in machine learning and causal inference are linear smoothers, where the prediction is a weighted average of the training outcomes. Some estimators, such as ordinary least squares and kernel ridge regression, allow for arbitrarily negative weights, which improve feature imbalance but often at the cost of increased dependence on parametric modeling assumptions and higher variance. By contrast, estimators like importance weighting and random forests…

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Design Stability in Adaptive Experiments: Implications for Treatment Effect Estimation

自适应实验的设计稳定性及其对处理效应估计的影响

We study the problem of estimating the average treatment effect (ATE) under sequentially adaptive treatment assignment mechanisms. In contrast to classical completely randomized designs, we consider a setting in which the probability of assigning treatment to each experimental unit may depend on prior assignments and observed outcomes. Within the potential outcomes framework, we propose and analyze two natural estimators for the ATE: the inverse propensity weighted (IPW)…

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A generalized tetrad constraint for testing conditional independence given a latent variable

检验给定潜变量条件独立性的广义四元约束

The tetrad constraint is widely used to test whether four observed variables are conditionally independent given a latent variable, based on the fact that if four observed variables following a linear model are mutually independent after conditioning on an unobserved variable, then products of covariances of any two different pairs of these four variables are equal. It is an important tool for discovering a latent common cause or distinguishing between alternative linear…

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Constructive Instrumental Variable Identification and Inference with Many Weak Interaction Moments

利用大量弱交互矩的构造性工具变量识别与推断

Instrumental variable methods are widely used for causal inference, but identification becomes especially challenging when instruments are weak and potentially invalid. These challenges are particularly pronounced in Mendelian randomization, where genetic variants serve as instruments and violations of exclusion restriction or independence assumptions are common. We propose MAGIC, a constructive and assumption-lean framework that achieves identification even when all…

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Linear models for causal inference under network interference

网络干扰下因果推断的线性模型

In causal inference, interference occurs when the treatment of one unit may affect the outcomes of other units. The goal of this work is to serve as a guide to the use of linear outcome modeling for estimating causal effects in settings where interference may pose a challenge to identification and estimation, such as spatial and network data. We demonstrate that, under a linear model, causal effects of binary and continuous treatments can be identified in terms of regression…

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When Bayes goes bad: Weakly-regularized covariate adjustment leads to a biased estimate of prevalence

当贝叶斯方法失效:弱正则化协变量调整导致患病率估计偏倚

When estimating population prevalence from a non-random sample, it is important to adjust for differences between sample and population. However, adjustment for multiple factors requires analysis that can be difficult to understand and validate. In this manuscript, we explore an unexpected downward trend of estimates when covariates are added sequentially to a Bayesian hierarchical model for the estimation of the prevalence of SARS-CoV-2 specific antibodies in an Australian…

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