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Principled Inference in Dense High-Dimensional Linear Models via Local Conditional Sparsity

基于局部条件稀疏性的稠密高维线性模型原则化推断

High-dimensional inference methods often rely on coefficient sparsity, an assumption that can be restrictive when signals are dense but individually weak. In such settings, valid inference may still be possible if the covariates exhibit sparse conditional dependence. Motivated by this observation, we propose Neighborhood-Localized Nested Regression (NLNR), a framework for coordinatewise inference in high-dimensional linear models with potentially dense coefficients. The…

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Average Marginal Effects in One-Step Partially Linear Instrumental Regressions

一步部分线性工具变量回归中的平均边际效应

We propose a novel procedure for estimating and conducting inference on average marginal effects in partially linear instrumental regressions using Reproducing Kernel Hilbert Space methods. Our procedure relies on a single regularization parameter. We obtain the consistency and asymptotic normality of our estimator. Since the variance of the limiting distribution has a complex analytical form, we propose a Bayesian bootstrap method to conduct inference and establish its…

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Detecting critical treatment effect bias in small subgroups

小子群中关键处理效应偏差的检测

Randomized trials are considered the gold standard for making informed decisions in medicine, yet they often lack generalizability to the patient populations in clinical practice. Observational studies, on the other hand, cover a broader patient population but are prone to various biases. Thus, before using an observational study for decision-making, it is crucial to benchmark its treatment effect estimates against those derived from a randomized trial. We propose a novel…

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Quantifying Individual Risk for Binary Outcomes

二元结果下的个体风险量化

Understanding treatment effect heterogeneity is crucial for reliable decision-making in treatment evaluation and selection. The conditional average treatment effect (CATE) is widely used to capture treatment effect heterogeneity induced by observed covariates and to design individualized treatment policies. However, it is an average metric within subpopulations, which prevents it from revealing individual risk, potentially leading to misleading results. This article fills…

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Variable-Length Markov Chains on Finite Quivers: Boundary-Window Identifiability, Exact Depth, and Local Rank Comparison

有限箭图上的变长马尔可夫链:边界窗口识别、精确深度与局部秩比较

Variable-length Markov chains on finite quivers provide a natural framework for context-dependent stochastic growth under incidence constraints. I study quiver-valued variable-length Markov chains observed through finite boundary windows and develop a first-order theory of visible-depth identifiability via stationary visible one-step transition laws and their restricted differentials on prescribed tangent blocks. For visible depth $m$, the main object is the stationary…

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Econometric Inference with Machine-Learned Proxies: Partial Identification via Data Combination

机器学习代理变量下的计量推断:通过数据组合实现部分识别

Empirical researchers increasingly use upstream machine-learning (ML) methods to construct proxies for latent target variables from complex, unstructured data. A naive plug-in use of such proxies in downstream econometric models, however, can lead to biased estimation and invalid inference. This paper develops a framework for partial identification and inference in general moment models with ML-generated proxies. Our approach does not require restrictive assumptions on the…

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Causal mediation in cluster-randomized trials with multiple mediators: spillover-aware decomposition, identification, and semiparametric efficient inference

多中介整群随机试验的因果中介分析:溢出分解、识别与有效推断

Causal mediation analysis in cluster-randomized trials (CRTs) is complicated by the presence of multiple mediators, intracluster correlation, and within-cluster interference. Existing mediation methods often fall short in accommodating these features simultaneously, and semiparametric efficient estimators that fully address them remain unavailable. We develop a unified framework that defines a class of mediation effect estimands, including exit indirect effects, exit…

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Transfer Learning for Moderate-Dimensional Ridge-Regularized Robust Linear Regression

中等维度岭正则化稳健线性回归的迁移学习

This paper studies transfer learning for ridge-regularized robust linear regression in the moderate-dimensional regime, where the number of predictors is of the same order as the sample size and the regression coefficients are not assumed to be sparse. We propose Trans-RR, which combines a robust ridge estimator from a source study with a robust ridge correction based on the target study. Under mild assumptions, we characterize the asymptotic estimation error of the proposed…

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Orthogonal machine learning for conditional odds and risk ratios

条件优势比与风险比的正交机器学习

Conditional effects are commonly used measures for understanding how treatment effects vary across different groups, and are often used to target treatments/interventions to groups who benefit most. In this work we review existing methods and propose novel ones, focusing on the odds ratio (OR) and the risk ratio (RR). While estimation of the conditional average treatment effect (ATE) has been widely studied, estimators for the OR and RR lag behind, and cutting edge…

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Estimating heterogeneous treatment effects with survival outcomes via a deep survival learner

利用深度生存学习器估计生存结局的异质性处理效应

Estimating heterogeneous treatment effects in survival settings is complicated by right censoring as well as the time-varying nature of the estimand. While the conditional average treatment effect (CATE) provides a natural target, most existing approaches focus on a single prespecified time point and do not account for the temporal trajectory, leading to instability in estimation. We propose a deep survival learner (DSL) for estimating heterogeneous treatment effects with…

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Differentially Private Estimation and Inference in High-Dimensional Regression with FDR Control

高维回归中的差分隐私估计与推断及FDR控制

This paper proposes new methodologies for conducting practical differentially private (DP) estimation and inference in high-dimensional linear regression. We first introduce a DP Bayesian Information Criterion (DP-BIC) for selecting the unknown sparsity parameter in differentially private sparse linear regression (DP-SLR), eliminating the need for prior knowledge of model sparsity, which is a requisite in the existing literature. Next, we develop the DP debiased algorithm…

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Large SVARs

大型结构向量自回归模型

We develop a new algorithm for inference in structural vector autoregressions (SVARs) identified with sign restrictions that can accommodate big data and modern identification schemes. The key innovation of our approach is to move beyond the traditional accept-reject framework commonly used in sign-identified SVARs. We show that an elliptical slice within Gibbs sampler can deliver dramatic gains in computational speed and render previously infeasible applications tractable.…

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Model-Robust Direct Effect Under Confounder-Mediator Ambiguity

混杂变量与中介角色不明时的模型稳健直接效应

Direct effect analyses usually require deciding whether a focal variable is a pre-exposure confounder or a post-exposure mediator. In observational studies, that distinction may be unclear because timing is measured coarsely or the variable reflects an evolving process. Considering the average treatment effect (ATE) and the natural direct effect (NDE) as a common notion of the direct effect when the focal variable is a confounder and a mediator, respectively, we show that,…

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Conformal Inference for Experimental Attrition in Social Science Research

社会科学实验样本流失的共形推断

Attrition in survey and field experiments presents a challenge for social science research. Common approaches to deal with this problem -- such as complete case analysis, multiple imputation, and weighting methods -- rely on strong assumptions that may not hold in practice. This paper introduces a new method that combines recent advances in statistical inference with established tools for handling missing data. The approach produces prediction intervals for treatment effects…

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Policy-Aware Design of Large-Scale Factorial Experiments

面向政策选择的大规模析因实验设计

Digital firms routinely run many online experiments on shared user populations. When product decisions are compositional, such as combinations of interface elements, flows, messages, or incentives, the number of feasible interventions grows combinatorially, while available traffic remains limited. Overlapping experiments can therefore generate interaction effects that are poorly handled by decentralized A/B testing. We study how to design large-scale factorial experiments…

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Training Neural Networks Embedded in Dynamic Discrete Choice Models

动态离散选择模型中嵌入神经网络的训练

We develop the first general-purpose estimator for infinite-horizon dynamic discrete choice models whose estimation problem, after pre-computation, is unencumbered by large systems of linear equations -- either imposed as constraints, or embedded in the objective function. Our unnested fixed point (UFXP) and optimal unnested fixed point (OUFXP) estimators exploit a dual representation of Bellman's equation to separate the utility parameters from the dynamic programming fixed…

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StationarityToolkit: Comprehensive Time Series Stationarity Analysis in Python

StationarityToolkit:Python 时间序列平稳性综合分析工具

Time-series stationarity is a property that statistical characteristics such as trend, variance, seasonality remain constant over time. It is considered fundamental to many forecasting and analysis methods. Different tests detect different types of non-stationarity: structural breaks or deterministic trends, clustered or time-dependent variance, stochastic or deterministic seasonality. A series might pass one test while failing another; single-test approaches seldom…

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Hypothesizing an effect size by considering individual variation

从个体差异出发设定效应大小假说

When designing and evaluating an experiment or observational study, it is useful to have a realistic hypothesis regarding the average treatment effect. We present an approach to conceptualizing this average by first considering a distribution of effects. We demonstrate with examples in medicine, economics, and psychology.

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Semiparametric Causal Mediation Analysis for Linear Models with Non-Gaussian Errors: Applications to Drug Treatment and Social Program Evaluation

非高斯误差线性模型的半参数因果中介分析:药物治疗与社会项目评估

\textbf{Background:} Mediation analysis is widely used to investigate how treatments and programs exert their effects, but standard ordinary least squares (OLS) inference can be unreliable when regression errors are non-Gaussian. In medical and public-health studies, this can affect whether indirect and direct effects are judged clinically or scientifically meaningful. \textbf{Methods:} We developed a semiparametric causal mediation framework for linear models allowing…

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Order-Constrained Spectral Causality for Multivariate Time Series

多变量时间序列的保序约束谱因果性

We introduce an operator-theoretic framework for analyzing directional dependence in multivariate time series based on order-constrained spectral non-invariance. Directional influence is defined as the sensitivity of second-order dependence operators to admissible, order-preserving temporal deformations of a designated source component, summarized through orthogonally invariant spectral functionals. We show that the resulting supremum--infimum dispersion functional is the…

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One-sample survival tests in the presence of non-proportional hazards in oncology clinical trials

肿瘤临床试验中非比例风险下的单样本生存检验

In oncology, conduct well-powered time-to-event randomized clinical trials may be challenging due to limited patietns number. Many designs for single-arm trials (SATs) have recently emerged as an alternative to overcome this issue. They rely on the (modified) one-sample log-rank test (OSLRT) under the proportional hazards to compare the survival curves of an experimental and an external control group. We extend Finkelstein's formulation of OSLRT as a score test by using a…

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Covariate Adjustment Cannot Hurt: Treatment Effect Estimation under Interference with Low-Order Outcome Interactions

低阶结局交互干扰下的协变量调整与处理效应估计

In randomized experiments, covariates are often used to reduce variance and improve the precision of treatment effect estimates. However, in many real-world settings, interference between units, where one unit's treatment affects another's outcome, complicates causal inference. This raises a key question: how can covariates be effectively used in the presence of interference? Addressing this challenge is nontrivial, as direct covariate adjustment, such as through regression,…

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Quantum Reservoir Computing for Realized Volatility Forecasting

用于已实现波动率预测的量子储备池计算

Recent advances in quantum computing have demonstrated its potential to significantly enhance the analysis and forecasting of complex classical data. Among these, quantum reservoir computing has emerged as a particularly powerful approach, combining quantum computation with machine learning for modeling nonlinear temporal dependencies in high-dimensional time series. As with many data-driven disciplines, quantitative finance and econometrics can hugely benefit from emerging…

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Fixed-Effects Models for Causal Inference in Longitudinal Cluster Randomized and Quasi-Experimental Trials

纵向整群随机与准实验试验中用于因果推断的固定效应模型

This article investigates the model-robustness of fixed-effects models for analyzing a broad class of longitudinal cluster trials (CTs) such as stepped-wedge, parallel-with-baseline and crossover designs, encompassing both randomized (CRTs) and quasi-experimental (CQTs) designs. We clarify a longstanding misconception in biostatistics, demonstrating that fixed-effects models, traditionally perceived as targeting only finite-sample conditional estimands, can effectively…

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